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    • 1. 发明授权
    • 1,2,4,5-Tetrahydro-3H-2-benzazepin-3-ones
    • 1,2,4,5-四氢-3H-2-苯并氮杂-3-酮
    • US4080449A
    • 1978-03-21
    • US819279
    • 1977-07-27
    • Paul CroisierLudovic Rodriquez
    • Paul CroisierLudovic Rodriquez
    • A61K31/395A61P25/28C07C17/14C07C17/16C07C25/02C07C57/58C07C57/60C07D223/16C07D405/12A61K31/55
    • C07D223/16C07C17/14C07C17/16C07C25/02C07C57/58C07C57/60
    • New physiologically active 1,2,4,5-tetrahydro-3H-2-benzazepin-3-ones having the general formula ##STR1## wherein R.sub.1 is hydrogen or phenyl, R.sub.2 is hydrogen, alkyl, C.sub.3 -C.sub.6 -alkenyl, C.sub.1 -C.sub.4 -acyl, hydroxyalkyl, alkoxyalkyl, mono- or dialkylaminoalkyl, cyanoalkyl, alkoxyacetyl, carbamoylalkyl, acetamido-C.sub.2 -C.sub.5 -alkyl, alkoxycarbonylalkyl or (tetrahydro-2H-pyran-2-yloxy)alkyl, the alkyl and the alkoxy radicals having 1 to 5 carbon atoms, R.sub.4 is hydrogen or C.sub.1 -C.sub.4 -alkyl, R.sub.5 is hydrogen, C.sub.1 -C.sub.4 -alkyl or phenyl, R.sub.7 is hydrogen, halogen or C.sub.1 -C.sub.4 -alkoxy and R.sub.8 is hydrogen, halogen or C.sub.1 -C.sub.4 -alkyl, at least one of the symbols R.sub.1 to R.sub.8 being other hydrogen, processes for the preparation thereof and pharmaceutical compositions containing the same. In particular, the compounds of this invention are useful in the treatment of memory disorders.
    • 具有通式“IMAGE”的新的生理活性的1,2,4,5-四氢-3H-2-苯并氮杂-3-酮,其中R 1是氢或苯基,R 2是氢,烷基,C 3 -C 6 - 烯基, C 4 - 酰基,羟基烷基,烷氧基烷基,一或二烷基氨基烷基,氰基烷基,烷氧基乙酰基,氨基甲酰基烷基,乙酰氨基-C 2 -C 5烷基,烷氧基羰基烷基或(四氢-2H-吡喃-2-基氧基)烷基,烷基和烷氧基具有1 至5个碳原子,R 4为氢或C 1 -C 4烷基,R 5为氢,C 1 -C 4 - 烷基或苯基,R 7为氢,卤素或C 1 -C 4烷氧基,R 8为氢,卤素或C 1 -C 4烷基 ,R1至R8中的至少一个为其它氢,其制备方法和含有该化合物的药物组合物。 特别地,本发明的化合物可用于记忆障碍的治疗。
    • 3. 发明授权
    • Thieno[3,4-d]pyrimidines
    • 噻吩并[8,3-d {9嘧啶
    • US3931204A
    • 1976-01-06
    • US434116
    • 1974-01-17
    • Paul Croisier
    • Paul Croisier
    • C07D333/38C07D498/04C07D239/00
    • C07D333/38
    • Thieno[3,4-d]pyrimidines of the general formula: ##SPC1##Wherein R.sub.1 is hydrogen, halogen, alkyl, alkoxy, amino, alkylamino, allylamino, hydroxy-alkylamino, cycloalkylamino, phenylamino, dialkylamino, di(hydroxyalkyl)-amino, alkyl-hydroxyalkyl-amino, pyrrolidino, piperidino, alkylpyrrolidino, alkylpiperidino, morpholino, alkyl-2-morpholino, alkyl-3-morpholino, dialkyl-3,5-morpholino, N-methylpiperazino, all said alkyl having 1 to 7 carbon atoms, said alkoxy having 1 to 5 carbon atoms and said cycloalkyl having 3 to 6 carbon atoms, R.sub.2 has the same meanings as R.sub.1 except alkyl and with the proviso that R.sub.2 is other than hydrogen or halogen, when R.sub.1 represents hydrogen or halogen and R.sub.3 is hydrogen or alkyl having 1 to 7 carbon atoms, as well as the addition salts thereof with pharmaceutically acceptable acids are, in particular, active on the cardiovascular system. Processes for their preparation are given.
    • 噻吩并[3,4-d]嘧啶,其通式如下:
    • 5. 发明授权
    • Apparatus for handling a load by arm, notably for a truck or trailer
    • 用于通过手臂处理负载的装置,特别是用于卡车或拖车
    • US5018932A
    • 1991-05-28
    • US544695
    • 1990-07-23
    • Jean-Paul Croisier
    • Jean-Paul Croisier
    • B60P1/48B60P1/64
    • B60P1/6463Y10S414/132
    • The invention is a handling apparatus for a truck, to be mounted on a truck chassis. A jib is connected to a rigid arm, a crank arm and a disengaged frame, to form the apparatus. The arms can be locked into position by a releasable locking mechanism. Three jacks are positioned in series to manipulate the jib, rigid arm, crank arm and disengaged frame. The handling apparatus is releasably secured on the truck chassis by a second releasable locking mechanism. A load can be lifted to the vertical, horizontal and dumping positions by changing the positions of the crank arm, rigid arm and jib arm.
    • 本发明是一种用于卡车的处理装置,其安装在卡车底盘上。 起重臂连接到刚性臂,曲柄臂和分离框架,以形成装置。 臂可以通过可释放的锁定机构锁定到位。 三个千斤顶串联定位以操纵起重臂,刚性臂,曲柄臂和分离架。 处理装置通过第二可释放锁定机构可释放地固定在卡车底盘上。 通过改变曲柄臂,刚性臂和起重臂的位置,可以将负载提升到垂直,水平和倾倒位置。