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1. 发明授权

US5412975A Universal inlet for airborne-particle size-selective sampling 失效
标题翻译：用于空气粒子尺寸选择性取样的通用入口
公开(公告)号：US5412975A
公开(公告)日：1995-05-09
申请号：US152461
申请日：1993-11-12
申请人： Otto G. Raabe , Stephen V. Teague
发明人： Otto G. Raabe , Stephen V. Teague
IPC分类号： B01D45/04 , G01N1/22 , G01N1/02
CPC分类号： G01N1/2208 , B01D45/04 , G01N2001/2223
摘要： A universal airborne-particle size-selective inlet (10) for separating particles (82) larger than a cut size from particles (84) smaller than the cut size is disclosed. The larger particles (82) are separated by inertial collection as they are drawn into the apparatus (10) in an air stream (78) which exits jet orifices (46) aligned with collector holes (34) leading to closed stagnation chambers (24). The larger particles (82) pass through the collector holes (34) and into the stagnation chambers (24) where they remain. The smaller particles (84) are carried by the flowing airstream (78) that turns at, and passes by, the collector holes (34) to an external downstream small particle collection device. The apparatus (10) can be used for any flow rate or cut size based on aerodynamic conditions and dimensional ratios that relate the jet orifice (46) sizes to the sampling flow rate, the throat depth of the jet orifices (46), and the distance from the internal exit of the jet orifices ( 46) to the entrance of the collector holes (34).
摘要翻译：公开了一种用于从小于切割尺寸的颗粒（84）分离大于切割尺寸的颗粒（82）的通用气载粒度选择性入口（10）。当空气流（78）离开与通向闭合停滞室（24）的收集器孔（34）对齐的喷射孔（46））的空气流中时，较大的颗粒（82）被惯性收集分离，。较大的颗粒（82）通过收集器孔（34）并进入滞留室（24），在那里它们保留。较小的颗粒（84）由流动的空气流（78）承载，该空气流通过收集器孔（34）转过并流过外部的下游小颗粒收集装置。基于空气动力学条件和尺寸比率，装置（10）可用于任何流量或切割尺寸，所述空气动力学条件和尺寸比将射流孔（46）尺寸与采样流速，喷射孔（46）的喉部深度和从喷射孔（46）的内部出口到收集器孔（34）的入口的距离。

2. 发明授权

US5322057A Intermittent signal actuated nebulizer synchronized to operate in the exhalation phase, and its method of use 失效
标题翻译：间歇信号启动雾化器同步运行在呼气阶段及其使用方法
公开(公告)号：US5322057A
公开(公告)日：1994-06-21
申请号：US645579
申请日：1991-01-24
申请人： Otto G. Raabe , James I. C. Lee , James C. Hathaway
发明人： Otto G. Raabe , James I. C. Lee , James C. Hathaway
IPC分类号： A61M13/00 , A61M11/06 , A61M15/00 , A61M16/00 , A61M16/16 , A62B7/04 , B05B17/06 , F16K31/26
CPC分类号： A61M16/14 , A61M11/042 , A61M15/00 , A61M15/0018 , A61M16/1065 , A61M16/16 , A61M11/06 , A61M2016/0024 , A61M2205/707
摘要： A self-contained, high capacity nebulizer, having automatic mixing and temperature control features is provided, and its method of use. The nebulizer is designed for use in conjunction with mechanical respirators, ventilators, or breathing machines, and for this purpose will use electrical signals generated by or received from the respirator to automatically control and synchronize the nebulizing and mixing functions such that nebulization occurs only during the exhalation phase of the respiratory function to load the gas passageway of the respirator to the patient with a standardized dose of medicinal aerosol. Upon commencement of the inhalation phase, the aerosol in the gas passageway is ventilated into the lungs of the patient to which it is attached.
摘要翻译：提供具有自动混合和温度控制功能的独立，高容量雾化器及其使用方法。喷雾器设计用于与机械呼吸器，呼吸机或呼吸机一起使用，为此，将使用由呼吸器产生或接收的电气信号来自动控制和同步雾化和混合功能，使雾化仅在呼吸功能的呼气阶段，以标准剂量的药用气雾剂将呼吸器的气体通道装载到病人身上。在吸入阶段开始时，气体通道中的气溶胶通气进入与其连接的患者的肺部。

3. 发明授权

US5287849A Medicinal aerosol delivery system and method of use 失效
标题翻译：药用气雾剂输送系统及使用方法
公开(公告)号：US5287849A
公开(公告)日：1994-02-22
申请号：US919585
申请日：1992-07-24
申请人： Samuel D. Piper , David A. Blackney , Lysa S. Kinoshita , Russell T. Reid , Otto G. Raabe , James I. C. Lee
发明人： Samuel D. Piper , David A. Blackney , Lysa S. Kinoshita , Russell T. Reid , Otto G. Raabe , James I. C. Lee
IPC分类号： A61M15/00 , A61M16/08 , A62M16/10
CPC分类号： A61M16/08 , A61M15/0086 , Y10S128/912
摘要： A method and apparatus for administering medicinal aerosol to a patient's lungs through an endotracheal tube (22) connected to a ventilator (100) or other respiratory apparatus, in which a charging volume (26) connected to a nebulizer (102) for generating medicinal aerosol is inserted between the ventilator (100) and the endotracheal tube (22), such that the charging volume (26) is filled with medicinal aerosol during patient exhalation, and the medicinal aerosol in the charging volume (26) is delivered into the endotracheal tube during patient inhalation. Additional amounts of medicinal aerosol are delivered into the endotracheal tube (22) during patient inhalation through hose (24) between the charging volume (26) and the nebulizer (102).
摘要翻译：一种用于通过连接到通气机（100）或其它呼吸装置的气管插管（22）向患者的肺部施用药用气溶胶的方法和装置，其中连接到用于产生药用气雾剂的喷雾器（102）的充电容积（26）插入到呼吸机（100）和气管内管（22）之间，使得充气体积（26）在患者呼气期间被填充有药物气溶胶，并且将充电体积（26）中的药物气溶胶输送到气管内管在患者吸入期间。在患者通过充电容积（26）和喷雾器（102）之间的软管（24）吸入时，额外量的药用气溶胶被输送到气管内管（22）中。

4. 发明授权

US5080093A Intermittant signal actuated nebulizer 失效
标题翻译：间歇信号启动雾化器
公开(公告)号：US5080093A
公开(公告)日：1992-01-14
申请号：US585616
申请日：1990-09-20
申请人： Otto G. Raabe , James I. C. Lee
发明人： Otto G. Raabe , James I. C. Lee
IPC分类号： A61M11/06 , A61M15/00 , A61M16/00 , A61M16/16
CPC分类号： A61M15/00 , A61M15/0018 , A61M16/1065 , A61M16/16 , A61M11/06 , A61M2016/0024
摘要： A self-contained, high capacity nebulizer, having automatic mixing and temperature control features is provided. The nebulizer may be adapted for use in conjunction with mechanical respirators, ventilators, or breathing machines, and for this purpose will use electrical signals generated by or received from the respirator to automatically control the nebulizing and mixing functions such that nebulization occurs intermittently, that is, only during the inhalation phase of the respiratory function. The nebulizer may also be adapted for manual and/or continuous use by providing an external electrical signal generator to manually control the nebulization and mixing functions.
摘要翻译：提供独立，高容量的雾化器，具有自动混合和温度控制功能。喷雾器可以适用于机械呼吸器，呼吸机或呼吸机，并且为此目的将使用由呼吸器产生的或从呼吸器接收的电信号来自动控制雾化和混合功能，使得喷雾间歇性发生，即，仅在呼吸功能的吸入阶段。喷雾器还可以通过提供外部电信号发生器手动控制雾化和混合功能而适于手动和/或连续使用。

5. 发明授权

US4832012A Intermittent signal actuated nebulizer 失效
标题翻译：间歇信号启动雾化器
公开(公告)号：US4832012A
公开(公告)日：1989-05-23
申请号：US71202
申请日：1987-07-08
申请人： Otto G. Raabe , James I. C. Lee
发明人： Otto G. Raabe , James I. C. Lee
IPC分类号： A61M16/00 , A61M15/00 , A61M16/16
CPC分类号： A61M16/16 , A61M15/0018
摘要： A self-contained, high capacity nebulizer, having automatic mixing and temperature control features is provided. The nebulizer may be adapted for use in conjunction with mechanical respirators, ventilators, or breathing machines, and for this purpose will use electrical signals generated by or received from the respirator to automatically control the nebulizing and mixing functions such that nebulization occurs intermittently, that is, only during the inhalation phase of the respiratory function. The nebulizer may also be adapted for manual and/or continuous use by providing an external electrical signal generator to manually control the nebulization and mixing functions.

6. 发明授权

US5287847A Universal nebulizer 失效
标题翻译：通用雾化器
公开(公告)号：US5287847A
公开(公告)日：1994-02-22
申请号：US919810
申请日：1992-07-24
申请人： Samuel D. Piper , Otto G. Raabe , James I. C. Lee , Gordon A. Wong
发明人： Samuel D. Piper , Otto G. Raabe , James I. C. Lee , Gordon A. Wong
IPC分类号： A61M11/06 , B05B7/00 , A61M16/00
CPC分类号： B05B7/0012 , A61M11/06
摘要： A nebulizer (10) for generating high concentrations of inhalable medicinal aerosols over a wide range of flow rates and mass outputs for medical inhalation therapy applications. A primary orifice (26), secondary orifice (44), inter-orifice gap (54), stagnation baffle (60), and spray gap (66) are scalable within defined parameters to provide any desired flow rate or mass output. The nebulizer is ideally suited for inhalation therapy of infants and children and can provide aerosols with flow rates ranging from less than 1 liter per minute to approximately 3 liters per minute at normal compressed gas pressures. The design parameters can also be scaled within defined limits to produce greater flows for treatment of adults or for use in other applications requiring high volumetric flow rates.
摘要翻译：用于在医疗吸入治疗应用的广泛流量和质量输出范围内产生高浓度可吸入药用气溶胶的雾化器（10）。主要孔口（26），次级孔口（44），孔间间隙（54），停滞挡板（60）和喷射间隙（66）在规定的参数内可伸缩以提供任何所需的流速或质量输出。雾化器非常适用于婴儿和儿童的吸入治疗，并且可以在正常的压缩气体压力下提供流量范围从小于1升/分钟到约3升/分钟的气溶胶。设计参数也可以在限定的范围内缩放，以产生更大的流量用于治疗大人或用于需要高体积流量的其他应用。

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