专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20100113451A1 NOVEL PREVENTIVE AND/OR THERAPEUTIC AGENT FOR DIABETIC NEUROPATHY 审中-公开
标题翻译：新型预防和/或治疗糖尿病神经病变药物
公开(公告)号：US20100113451A1
公开(公告)日：2010-05-06
申请号：US12530745
申请日：2008-03-14
申请人： Toshiaki Aoki , Nobuhito Murai , Seiji Tamura , Hiroko Yamamoto , Nozomu Hamakawa
发明人： Toshiaki Aoki , Nobuhito Murai , Seiji Tamura , Hiroko Yamamoto , Nozomu Hamakawa
IPC分类号： A61K31/5375 , A61P25/00
CPC分类号： C07D265/30 , A61K31/5375
摘要： The present invention relates to an agent for preventing and/or treating diabetic neuropathy comprising a 2-[(substituted-inden-7-yloxy)methyl]morpholine of the formula (I) or a pharmaceutically acceptable salt thereof as an active ingredient. The invention is useful for providing an excellent agent for preventing and/or treating diabetic neuropathy, and particularly useful for providing an agent for preventing and/or treating diabetic motor neuropathy (such as muscle weakness disorder (such as muscle weakness disorder with inability to walk independently)), diabetic sensory neuropathy (such as paresthesia (such as vibration perception abnormality), allodynia, hypoesthesia (such as numbness of extremities or cold sensation), or pain), or diabetic autonomic neuropathy (such as stool abnormality (such as constipation or diarrhea), urination disorder, impotence, orthostatic hypotension, sudomotor dysfunction, abnormal heart rate variability, or delayed gastric emptying). Further, the invention is particularly useful for providing an agent for improving pathophysiology of diabetic neuropathy.
摘要翻译：本发明涉及用于预防和/或治疗糖尿病性神经病变的药剂，其包含式（I）的2 - [（取代 - 茚-7-基氧基）甲基]吗啉或其药学上可接受的盐作为活性成分。本发明可用于提供用于预防和/或治疗糖尿病性神经病变的优异剂，特别可用于提供用于预防和/或治疗糖尿病运动神经病变（如肌肉无力障碍（例如无力行走的肌肉无力障碍）独立）），糖尿病感觉神经病变（如感觉异常（如振动感知异常），异常性疼痛，麻醉（如四肢麻木或感冒）或疼痛）或糖尿病性自主神经病变（如便秘便秘）或腹泻），排尿障碍，阳ence，直立性低血压，苏体功能障碍，异常心率变异性或延迟胃排空）。此外，本发明特别可用于提供改善糖尿病性神经病变病理生理学的药剂。

2. 发明申请

US20130023535A1 METHOD OF PREVENTING AND/OR TREATING DIABETIC NEUROPATHY 审中-公开
标题翻译：预防和/或治疗糖尿病神经病变的方法
公开(公告)号：US20130023535A1
公开(公告)日：2013-01-24
申请号：US13592544
申请日：2012-08-23
申请人： TOSHIAKI AOKI , NOBUHITO MURAI , SEIJI TAMURA , HIROKO YAMAMOTO , NOZOMU HAMAKAWA
发明人： TOSHIAKI AOKI , NOBUHITO MURAI , SEIJI TAMURA , HIROKO YAMAMOTO , NOZOMU HAMAKAWA
IPC分类号： A61K31/5375 , A61P3/10
CPC分类号： C07D265/30 , A61K31/5375
摘要： The present invention relates to an agent for preventing and/or treating diabetic neuropathy comprising a 2-[(substituted-inden-7-yloxy)methyl]morpholine of the formula (I) or a pharmaceutically acceptable salt thereof as an active ingredient. The invention is useful for providing an excellent agent for preventing and/or treating diabetic neuropathy, and particularly useful for providing an agent for preventing and/or treating diabetic motor neuropathy (such as muscle weakness disorder (such as muscle weakness disorder with inability to walk independently)), diabetic sensory neuropathy (such as paresthesia (such as vibration perception abnormality), allodynia, hypoesthesia (such as numbness of extremities or cold sensation), or pain), or diabetic autonomic neuropathy (such as stool abnormality (such as constipation or diarrhea), urination disorder, impotence, orthostatic hypotension, sudomotor dysfunction, abnormal heart rate variability, or delayed gastric emptying). Further, the invention is particularly useful for providing an agent for improving pathophysiology of diabetic neuropathy.
摘要翻译：本发明涉及用于预防和/或治疗糖尿病性神经病变的药剂，其包含式（I）的2 - [（取代 - 茚-7-基氧基）甲基]吗啉或其药学上可接受的盐作为活性成分。本发明可用于提供用于预防和/或治疗糖尿病性神经病变的优异剂，特别可用于提供用于预防和/或治疗糖尿病运动神经病变（如肌肉无力障碍（例如无力行走的肌肉无力障碍）独立）），糖尿病感觉神经病变（如感觉异常（如振动感知异常），异常性疼痛，麻醉（如四肢麻木或感冒）或疼痛）或糖尿病性自主神经病变（如便秘便秘）或腹泻），排尿障碍，阳ence，直立性低血压，苏体功能障碍，异常心率变异性或延迟胃排空）。此外，本发明特别可用于提供改善糖尿病性神经病变病理生理学的药剂。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式