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    • 1. 发明申请
    • TOOTHPASTE COMPOSITION FOR DENTIN HYPERSENSITIVITY
    • 用于丹宁超敏性的牙膏组合物
    • US20140127142A1
    • 2014-05-08
    • US14126303
    • 2012-06-12
    • Noritaka TakahashiAtsushi Yamagishi
    • Noritaka TakahashiAtsushi Yamagishi
    • A61K8/58A61Q11/00
    • A61K8/58A61K6/0017A61K8/19A61K8/20A61K8/361A61K8/365A61K8/44A61K8/731A61Q11/00
    • Provided is a toothpaste composition for dentin hypersensitivity that effectively prevents pain attributed to dentin hypersensitivity, instantaneously and sufficiently seals the openings of dentinal tubules in an exposed dentinal surface, and has excellent sustainability of the effect of suppressing the pain attributed to dentin hypersensitivity. The toothpaste composition for dentin hypersensitivity comprises the following components (A), (B), and (C): (A) a powder having a sparingly water-soluble property selected from a fatty acid divalent metal salt (A-1) derived from a saturated fatty acid having from 12 to 18 carbon atoms, a fatty acid acyllysine (A-2) having an acyl group derived from a saturated fatty acid having from 12 to 18 carbon atoms, and a fatty acid acyltaurine divalent metal salt (A-3) having an acyl group derived from a saturated fatty acid having from 12 to 18 carbon atoms; (B) a desensitizing agent selected from potassium nitrate, potassium citrate, strontium chloride, and strontium acetate; and (C) water; in which a mass ratio ((A)/(B)) of the component (A) to the component (B) is from 0.02 to 0.5.
    • 提供一种用于牙质过敏的牙膏组合物,其有效地防止牙本质过敏引起的疼痛,瞬时和充分地密封暴露的牙质表面中的牙质小管的开口,并且具有抑制由牙本质过敏引起的疼痛的效果的优异的持续性。 用于牙本质过敏的牙膏组合物包括以下组分(A),(B)和(C):(A)具有少量水溶性的粉末,其选自脂肪酸二价金属盐(A-1)衍生自 具有12至18个碳原子的饱和脂肪酸,具有衍生自具有12至18个碳原子的饱和脂肪酸的酰基的脂肪酸酰基赖氨酸(A-2)和脂肪酸酰基牛磺酸二价金属盐(A- 3)具有衍生自具有12至18个碳原子的饱和脂肪酸的酰基; (B)选自硝酸钾,柠檬酸钾,氯化锶和乙酸锶的脱敏剂; 和(C)水; 其中组分(A)与组分(B)的质量比((A)/(B))为0.02至0.5。