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1. 发明申请

US20130316976A1 PHARMACEUTICAL PREPARATION 审中-公开
标题翻译：药物制剂
公开(公告)号：US20130316976A1
公开(公告)日：2013-11-28
申请号：US13983107
申请日：2012-03-01
申请人： Norbert Roewer , Jens Broscheit
发明人： Norbert Roewer , Jens Broscheit
IPC分类号： A61K47/48 , A61K31/05 , A61K9/00
CPC分类号： A61K47/4823 , A61K9/0019 , A61K9/19 , A61K31/05 , A61K47/61 , A61K47/6951
摘要： The invention relates to a pharmaceutical formulation that contains a complex of a propofol salt with a cyclodextrin. The invention makes it possible to provide propofol in a formulation that can be stored and that can be administered intravenously without problems.
摘要翻译：本发明涉及含有异丙酚盐与环糊精的复合物的药物制剂。本发明使得可以在可以储存的制剂中提供异丙酚并且可以静脉内施用而没有问题。

2. 发明授权

US09125953B2 Halogenated ether complex 有权
标题翻译：卤化醚络合物
公开(公告)号：US09125953B2
公开(公告)日：2015-09-08
申请号：US13522109
申请日：2011-01-14
申请人： Norbert Roewer , Jens Broscheit
发明人： Norbert Roewer , Jens Broscheit
IPC分类号： C08B30/18 , C08B37/16 , A01N43/04 , A61K31/715 , A61K47/48 , A61K9/00 , A61K31/08 , B82Y5/00 , A61K47/40
CPC分类号： A61K47/48969 , A61K9/0019 , A61K31/08 , A61K47/40 , A61K47/6951 , B82Y5/00 , C08B37/0015
摘要： The invention relates to a complex made of α-cyclodextrin and a halogenated ether, characterized by a content of the halogenated ether of at least 3 wt % of the total weight of the complex.
摘要翻译：本发明涉及由α-环糊精和卤代醚制成的络合物，其特征在于所述卤代醚的含量为所述络合物总重量的至少3重量％。

3. 发明授权

US08980882B2 Pharmaceutical preparation comprising permethylated cyclodextrin 有权
标题翻译：药物制剂，包括甲基化环糊精
公开(公告)号：US08980882B2
公开(公告)日：2015-03-17
申请号：US12936222
申请日：2009-04-01
申请人： Norbert Roewer , Jens Broscheit
发明人： Norbert Roewer , Jens Broscheit
IPC分类号： A61K31/5517 , A61K31/724 , A61K9/00 , A61K31/05 , A61K31/715
CPC分类号： A61K9/0019 , A61K9/006 , A61K31/05 , A61K31/715
摘要： The invention relates to a pharmaceutical preparation for applying a pharmaceutical agent. According to the invention, the preparation contains: a) a pharmaceutical agent which has an aromatic group or an aromatic part and the molecule of which has a maximum diameter of ≦2 nm; b) a permethylated cyclodextrin having a degree of substitution of 3 methyl groups per glucopyranose unit. The permethylated cyclodextrin and the pharmaceutical agent form a complex.
摘要翻译：本发明涉及用于施用药剂的药物制剂。根据本发明，该制剂包含：a）具有芳族基团或芳族部分并且其分子具有最大直径为＆amp; lE; 2nm的药剂; b）每个吡喃葡萄糖单元具有3个甲基取代度的全甲基化的环糊精。甲基化环糊精和药剂形成复合物。

4. 发明授权

US5718685A Stomach probe 失效
标题翻译：胃探头
公开(公告)号：US5718685A
公开(公告)日：1998-02-17
申请号：US825655
申请日：1997-04-03
申请人： Norbert Roewer , Volker Klute
发明人： Norbert Roewer , Volker Klute
IPC分类号： A61M25/00 , A61F2/958 , A61J15/00 , A61M1/00 , A61M23/00 , A61M25/02 , A61M29/00
CPC分类号： A61M25/02 , A61M25/1011 , A61J15/0003 , A61J15/0049 , A61M2025/0213 , A61M25/1002
摘要： A stomach probe has an aspiration tube (1) and a stomach balloon (7) which is to be held, by tensioning of the aspiration tube (1), in contact against the stomach wall (12) surrounding the cardiac orifice (5). The stomach balloon is connected to a pressure control device which is equipped to indicate at least two pressure stages, of which the lower one corresponds to the freely inflated state of the stomach balloon when the tube is untensioned, and the higher one corresponds to the tensioned state of the aspiration tube. The stomach balloon (7) is arranged on the aspiration tube at points which are at a short distance from each other, so that it assumes approximately a torus configuration in the inflated state. It is elastically resilient in the longitudinal direction of the tube.
摘要翻译：胃探针具有吸引管（1）和胃气囊（7），其通过吸引管（1）的张紧而与围绕心脏孔（5）的胃壁（12）接触而被保持。胃气球连接到压力控制装置，该压力控制装置被配备为指示至少两个压力级，其中下压力级对应于当未拉伸管时胃气球的自由膨胀状态，并且较高的压力级对应于张紧的抽吸管的状态。胃气囊（7）在彼此相距很短距离的点处布置在抽吸管上，使得其在充气状态下呈现大致圆环构型。它在管的纵向具有弹性弹性。

5. 发明申请

US20120296077A1 HALOGENATED ETHER COMPLEX 有权
标题翻译： HALOGENATED醚复合物
公开(公告)号：US20120296077A1
公开(公告)日：2012-11-22
申请号：US13522109
申请日：2011-01-14
申请人： Norbert Roewer , Jens Broscheit
发明人： Norbert Roewer , Jens Broscheit
IPC分类号： C08B37/16
CPC分类号： A61K47/48969 , A61K9/0019 , A61K31/08 , A61K47/40 , A61K47/6951 , B82Y5/00 , C08B37/0015
摘要： The invention relates to a complex made of α-cyclodextrin and a halogenated ether, characterized by a content of the halogenated ether of at least 3 wt % of the total weight of the complex.
摘要翻译：本发明涉及由α-环糊精和卤代醚制成的络合物，其特征在于所述卤代醚的含量为所述络合物总重量的至少3重量％。

6. 发明授权

US5462528A Stomach tube 失效
标题翻译：胃管
公开(公告)号：US5462528A
公开(公告)日：1995-10-31
申请号：US962031
申请日：1992-10-15
申请人： Norbert Roewer
发明人： Norbert Roewer
IPC分类号： A61F2/958 , A61J15/00 , A61M25/00
CPC分类号： A61J15/0003 , A61J15/0049 , A61J15/0061 , A61J15/0088 , A61M25/1009
摘要： A stomach tube having an inflatable balloon for closing the stomach opening and an indicator for indicating the balloon pressure at first and second predetermined pressure levels. After the stomach tube is inserted, the stomach balloon is inflated without the stomach tube under tension until the lower pressure level is indicated. The stomach tube is then tensioned until the higher pressure level is indicated. A nose stop is used to maintain the stomach tube tension.
摘要翻译：具有用于封闭胃口的可膨胀气囊的胃管和用于在第一和第二预定压力水平下指示球囊压力的指示器。在胃管插入后，胃气囊在没有胃管张力的情况下充气，直到指示较低的压力水平。然后将胃管张紧直到指示较高的压力水平。鼻塞用于保持胃管张力。

7. 发明授权

US09006215B2 Pharmaceutical preparation comprising propofol salt and cyclodextrin 有权
标题翻译：含有异丙酚盐和环糊精的药物制剂
公开(公告)号：US09006215B2
公开(公告)日：2015-04-14
申请号：US13983107
申请日：2012-03-01
申请人： Norbert Roewer , Jens Broscheit
发明人： Norbert Roewer , Jens Broscheit
IPC分类号： A61K47/48 , A61K31/05 , A61K47/40 , A61K9/00
CPC分类号： A61K47/4823 , A61K9/0019 , A61K9/19 , A61K31/05 , A61K47/61 , A61K47/6951
摘要： The invention relates to a pharmaceutical formulation that contains a complex of a propofol salt with a cyclodextrin. The invention makes it possible to provide propofol in a formulation that can be stored and that can be administered intravenously without problems.
摘要翻译：本发明涉及含有异丙酚盐与环糊精的复合物的药物制剂。本发明使得可以在可以储存的制剂中提供异丙酚并且可以静脉内施用而没有问题。

8. 发明申请

US20110028457A1 PHARMACEUTICAL PREPARATION COMPRISING PERMETHYLATED CYCLODEXTRIN 审中-公开
标题翻译：包含环糊精的药物制剂
公开(公告)号：US20110028457A1
公开(公告)日：2011-02-03
申请号：US12936222
申请日：2009-04-01
申请人： Norbert Roewer , Jens Broscheit
发明人： Norbert Roewer , Jens Broscheit
IPC分类号： A61K31/5517 , A61K47/40 , A61K31/05 , A61P29/00 , A61P25/00
CPC分类号： A61K9/0019 , A61K9/006 , A61K31/05 , A61K31/715
摘要： The invention relates to a pharmaceutical preparation for applying a pharmaceutical agent. According to the invention, the preparation contains: a) a pharmaceutical agent which has an aromatic group or an aromatic part and the molecule of which has a maximum diameter of ≦2 nm; b) a permethylated cyclodextrin having a degree of substitution of 3 methyl groups per glucopyranose unit. The permethylated cyclodextrin and the pharmaceutical agent form a complex.
摘要翻译：本发明涉及一种用于施用药剂的药物制剂。根据本发明，该制剂包含：a）具有芳族基团或芳族部分并且其分子具有最大直径为＆amp; lE; 2nm的药剂; b）每个吡喃葡萄糖单元具有3个甲基取代度的全甲基化的环糊精。甲基化环糊精和药剂形成复合物。

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