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1. 发明授权

US09034328B2 Anti-erbB3 antibody 有权
标题翻译：抗erbB3抗体
公开(公告)号：US09034328B2
公开(公告)日：2015-05-19
申请号：US13527733
申请日：2012-06-20
申请人： Nobuaki Takahashi
发明人： Nobuaki Takahashi
IPC分类号： A61K39/395 , C07K16/32 , A61K39/00
CPC分类号： C07K16/32 , A61K39/39558 , A61K2039/505 , A61K2039/507 , C07K2317/24 , C07K2317/76
摘要： The present invention relates to an antibody or an antibody fragment thereof which recognizes an extracellular domain of erbB3 and inhibit EGF-like ligand-dependent phosphorylation of erbB3, a DNA encoding the antibody or the antibody fragment thereof, a method of producing the antibody or the antibody fragment thereof, a therapeutic drug including the antibody or the antibody fragment thereof, and therapeutic application using the antibody or the antibody fragment thereof.
摘要翻译：本发明涉及识别erbB3的细胞外结构域并抑制erbB3的EGF样配体依赖性磷酸化的抗体或其抗体片段，编码抗体或其抗体片段的DNA，制备抗体或其抗体的方法其抗体片段，包括抗体或其抗体片段的治疗药物，以及使用抗体或其抗体片段的治疗应用。

2. 发明申请

US20140097837A1 OPTICALLY PUMPED MAGNETOMETER, MAGNETOENCEPHALOGRAPHY METER, AND MRI DEVICE 审中-公开
标题翻译：光电泵，磁光计和磁共振成像装置
公开(公告)号：US20140097837A1
公开(公告)日：2014-04-10
申请号：US14003507
申请日：2011-11-16
申请人： Nobuaki Takahashi
发明人： Nobuaki Takahashi
IPC分类号： G01R33/26 , A61B5/05
CPC分类号： A61B5/05 , A61B5/04008 , G01R33/26
摘要： An optical pumping magnetometer measures a magnetic field of a measurement object using optical pumping. The optical pumping magnetometer includes a nonmagnetic cell in which at least an alkali metal is enclosed and which has optical transparency and heat resistance, a laser beam irradiation unit which radiates a laser beam to the cell and optically pumps at least the alkali metal, a detecting unit which receives a transmission laser beam transmitted through the cell and detects a detection signal related to the magnetic field, and a high frequency voltage applying unit which applies a high frequency voltage to a pair of application units provided on the cell and heats the cell by dielectric heating.
摘要翻译：光泵浦磁力计使用光泵浦测量测量对象的磁场。光泵浦磁力计包括至少包含碱金属并且具有光学透明性和耐热性的非磁性电池，将激光束照射到电池并至少泵浦至少碱金属的激光束照射单元，检测接收通过单元发送的发送激光束并检测与磁场相关的检测信号的单元，以及高频电压施加单元，其向设置在单元上的一对应用单元施加高频电压，并通过电介质加热。

3. 发明申请

US20140041096A1 NON-SLIP FINISHED GLOVE AND METHOD FOR MANUFACTURING THE SAME 审中-公开
标题翻译：非滑动整理手套及其制造方法
公开(公告)号：US20140041096A1
公开(公告)日：2014-02-13
申请号：US13988608
申请日：2011-11-22
申请人： Nobuaki Takahashi
发明人： Nobuaki Takahashi
IPC分类号： A41D19/00
CPC分类号： A41D19/0082 , A41D19/01558 , A41D2500/10 , A41D2500/54
摘要： A non-slip finished glove includes: a glove main body made of fibers for covering a wearer's hand; a plurality of protrusions made of resin or rubber, the protrusions being fixed at least to a palm region of an outer face of the glove main body; and an air permeable coating layer that is laminated at least on a region other than the protrusions in the palm region of the outer face of the glove main body, in which the protrusions protrude from an outer face of the coating layer. The plurality of protrusions allows grip of an object and, since the coating layer is provided in regions other than the protrusions not to expose fibers of the glove main body, a sufficient gripping force can be exerted to firmly grip the object.
摘要翻译：防滑成品手套包括：由用于覆盖佩戴者的手的纤维制成的手套主体; 多个由树脂或橡胶制成的突起，突起至少固定在手套主体的外表面的手掌区域上; 以及至少层叠在所述手套主体的外表面的手掌区域中的突起以外的区域上的透气性涂层，其中所述突起从所述涂层的外表面突出。多个突起允许物体的抓握，并且由于涂层设置在除了不暴露手套主体的纤维的突起之外的区域中，因此可以施加足够的夹紧力以牢固地夹持物体。

4. 发明授权

US08568725B2 Method of treating transplant rejection with an anti-CD40 antibody 有权
标题翻译：用抗CD40抗体治疗移植排斥的方法
公开(公告)号：US08568725B2
公开(公告)日：2013-10-29
申请号：US10584345
申请日：2004-12-24
申请人： Nobuaki Takahashi , Toru Miura , Yoshinori Kitagawa , Aki Hirano
发明人： Nobuaki Takahashi , Toru Miura , Yoshinori Kitagawa , Aki Hirano
IPC分类号： A61K39/395 , C07K16/28
CPC分类号： C07K16/2878 , C07K2317/34 , C07K2317/52 , C07K2317/53 , C07K2317/56 , C07K2317/73 , C07K2317/732 , C07K2317/734 , C07K2317/76
摘要： A mutant of a potentially therapeutic anti-CD40 antibody is provided which mutant has reduced ADCC and CDC activities designed to be optimized as a pharmaceutical agent. A mutant of an agonistic anti-CD40 antibody, comprising mutation and/or substitution of at least one amino acid in the constant region to reduce the ADCC and/or CDC activities therein, and a mutant of an antagonistic anti-CD40 antibody, comprising at least one mutation or substitution in the constant region to reduce the ADCC and/or CDC activities therein, both mutants having at least a hinge region derived from a human IgG2.
摘要翻译：提供潜在治疗性抗CD40抗体的突变体，其突变体具有降低的ADCC和CDC活性，被设计为作为药剂优化。激动性抗CD40抗体的突变体，其包含恒定区中至少一个氨基酸的突变和/或取代以降低其中的ADCC和/或CDC活性，以及拮抗性抗-CD40抗体的突变体，其包含在恒定区域中至少一个突变或取代以减少其中的ADCC和/或CDC活性，两个突变体具有至少一个衍生自人IgG2的铰链区。

5. 发明授权

US08495012B2 System and method for managing root file system 有权
标题翻译：管理根文件系统的系统和方法
公开(公告)号：US08495012B2
公开(公告)日：2013-07-23
申请号：US12335854
申请日：2008-12-16
申请人： Shingo Nagai , Nobuaki Takahashi , Fumitomo Ohsawa
发明人： Shingo Nagai , Nobuaki Takahashi , Fumitomo Ohsawa
IPC分类号： G06F7/00 , G06F11/00
CPC分类号： G06F11/1435 , G06F11/2074
摘要： There is provided a system including a cluster 11, a cluster 12 and an image server 20. A host 101a constituting the cluster 11 has a root file system 111a used to operate the host 101a in a local disk. The image server 20 has a root file system 221a used to operate the host 101a, and the host 101a virtually constructs a root file system 121a by mounting the root file system 221a. When the root file system 111a is varied, the host 101a synchronizes the root file system 111a with the root file system 121a. The same applies to host 102a constituting the cluster 12.
摘要翻译：提供了包括集群11，集群12和映像服务器20的系统。构成集群11的主机101a具有用于在本地磁盘中操作主机101a的根文件系统111a。图像服务器20具有用于操作主机101a的根文件系统221a，并且主机101a通过安装根文件系统221a来虚拟地构建根文件系统121a。当根文件系统111a变化时，主机101a将根文件系统111a与根文件系统121a同步。这同样适用于构成集群12的主机102a。

6. 发明授权

US08455283B2 Organic electronic element and its manufacturing method 有权
标题翻译：有机电子元件及其制造方法
公开(公告)号：US08455283B2
公开(公告)日：2013-06-04
申请号：US13254886
申请日：2010-03-03
申请人： Nobuaki Takahashi , Hiroaki Yamagishi
发明人： Nobuaki Takahashi , Hiroaki Yamagishi
IPC分类号： H01L21/00
CPC分类号： H01L51/5256 , H01L51/0059 , H01L51/0084 , H01L51/0085 , H01L51/0087 , H01L51/0088 , H01L51/0097 , Y02E10/549 , Y02P70/521
摘要： The present invention provides an organic electronic element manufacturing method which provides a low manufacturing cost and excellent performance stability, and specifically an organic electronic element manufacturing method which provides a low manufacturing cost, and minimizes emission unevenness, lowering of emission efficiency and shortening of lifetime due to deterioration of gas barrier property of sealing. The organic electronic element manufacturing method is featured in that it comprises the steps of forming an organic electronic structure composed of a first electrode, at least one organic layer and a second electrode on a flexible substrate, and applying a flexible sealing substrate to the organic electronic structure, followed by heating treatment, wherein a heating temperature, at which the heating treatment is carried out, is less than Tg (glass transition temperature) of the substrate and not less than Tg of the sealing substrate.
摘要翻译：本发明提供了一种提供低制造成本和优异的性能稳定性的有机电子元件制造方法，特别是提供低制造成本的有机电子元件制造方法，并且最小化发射不均匀性，降低发光效率和缩短寿命密封的气体阻隔性劣化。有机电子元件制造方法的特征在于，其包括以下步骤：在柔性基板上形成由第一电极，至少一个有机层和第二电极组成的有机电子结构，以及将柔性密封基板施加到有机电子结构，然后进行加热处理的加热处理，其中进行加热处理的加热温度小于基板的Tg（玻璃化转变温度），并且不小于密封基板的Tg。

7. 发明授权

US08437140B2 Electronic package, display, and electronic device 有权
标题翻译：电子封装，显示和电子设备
公开(公告)号：US08437140B2
公开(公告)日：2013-05-07
申请号：US12988990
申请日：2009-03-02
申请人： Kohei Kitagawa , Nobuaki Takahashi , Masahiro Imai , Koichi Yoshioka
发明人： Kohei Kitagawa , Nobuaki Takahashi , Masahiro Imai , Koichi Yoshioka
IPC分类号： H05K5/00
CPC分类号： H05K1/0215 , G02F1/133308 , G02F1/13452 , G02F2001/133314 , G02F2001/133317 , G02F2001/13332 , G02F2001/133322 , G02F2001/133325 , G02F2001/133334 , G02F2201/465 , H05K1/0393 , H05K2201/10393
摘要： An FPC board (1) is mounted on a front bezel (BZ1) and a rear bezel (BZ2). The outer claw (CW1) of the front bezel (BZ1) and the inner claw (CW2) of the rear bezel (BZ2) are engaged with each other while holding the ground portion (12) of the FPC board (1) therebetween.
摘要翻译： FPC板（1）安装在前挡板（BZ1）和后挡板（BZ2）上。前面板（BZ1）的外爪（CW1）和后边框（BZ2）的内爪（CW2）彼此接合，同时保持FPC基板（1）的接地部分（12）。

8. 发明申请

US20120248602A1 SEMICONDUCTOR DEVICE 有权
标题翻译：半导体器件
公开(公告)号：US20120248602A1
公开(公告)日：2012-10-04
申请号：US13494537
申请日：2012-06-12
申请人： Nobuaki TAKAHASHI , Masahiro KOMURO , Satoshi MATSUI
发明人： Nobuaki TAKAHASHI , Masahiro KOMURO , Satoshi MATSUI
IPC分类号： H01L23/48
CPC分类号： H01L23/481 , H01L21/76898 , H01L24/11 , H01L24/13 , H01L2224/05571 , H01L2224/05573 , H01L2224/05624 , H01L2224/05684 , H01L2224/13009 , H01L2224/131 , H01L2224/13562 , H01L2224/1357 , H01L2224/13644 , H01L2224/13664 , H01L2224/17181 , H01L2924/00014
摘要： In this semiconductor device, the through-hole is formed in the substrate, and is located under the conductive pattern. The insulating layer is located at the bottom surface of the through-hole. The conductive pattern is located on one surface side of the substrate. The opening pattern is formed in the insulating layer which is located between the through-hole and the conductive pattern, where the distance r3 from the circumference of the opening pattern to the central axis of the through-hole is smaller than the distance r1 in the through-hole. By providing the opening pattern, the conductive pattern is exposed at the bottom surface of the through-hole. The bump is located on the back surface side of the substrate, and is formed integrally with the through-electrode.
摘要翻译：在该半导体装置中，通孔形成在基板上，位于导电图案的下方。绝缘层位于通孔的底面。导电图案位于基板的一个表面侧。开口图案形成在位于通孔和导电图案之间的绝缘层中，其中从开口图案的周边到通孔的中心轴线的距离r3小于通孔中的距离r1 通孔。通过设置开口图案，导电图案在通孔的底面露出。凸块位于基板的背面侧，与贯通电极一体形成。

9. 发明申请

US20120229384A1 DISPLAY DEVICE WITH LOCATION DETECTION FUNCTION AND INPUT LOCATION DETECTION SYSTEM 审中-公开
标题翻译：具有位置检测功能和输入位置检测系统的显示设备
公开(公告)号：US20120229384A1
公开(公告)日：2012-09-13
申请号：US13513165
申请日：2010-11-12
申请人： Noriyuki Nakane , Nobuaki Takahashi
发明人： Noriyuki Nakane , Nobuaki Takahashi
IPC分类号： G06F3/033
CPC分类号： G06F3/0386 , G06F3/03545 , G06F3/0412 , G06F3/0416
摘要： An input position detection system (1) according to the present invention includes a laser pointer (50) that emits infrared light, and a liquid crystal display device (10) that detects a position of an input from the input pointer (50) by detecting the infrared light. The liquid crystal display device (10) includes optical sensor elements (30), a received light intensity calculation circuit (31), a coordinate extracting circuit (32), a combining and calculating circuit (33), an input signal calculation circuit (35), and the like. The combining and calculating circuit (33) calculates the intensities of received light at respective coordinate positions on the basis of the information obtained by the coordinate extracting circuit (32) and the received light intensity calculation circuit (31). The input signal calculation circuit (35) calculates a distance of the laser pointer (50) from an image display surface, and detects the three-dimensional position of the laser pointer on the basis of the received light intensity information. The input position detection system thus handles three-dimensional pointing with a higher degree of accuracy.
摘要翻译：根据本发明的输入位置检测系统（1）包括发射红外光的激光指示器（50）和液晶显示装置（10），其通过检测来自输入指针（50）的输入位置来检测红外灯。液晶显示装置（10）包括光学传感器元件（30），接收光强度计算电路（31），坐标提取电路（32），组合计算电路（33），输入信号计算电路）等。组合计算电路（33）根据坐标提取电路（32）和接收光强度计算电路（31）得到的信息，算出各坐标位置的接收光强度。输入信号计算电路（35）计算激光指示器（50）与图像显示面的距离，并且根据所接收的光强度信息检测激光指示器的三维位置。因此，输入位置检测系统以更高的准确度处理三维指向。

10. 发明申请

US20120211872A1 SEMICONDUCTOR DEVICE 失效
标题翻译：半导体器件
公开(公告)号：US20120211872A1
公开(公告)日：2012-08-23
申请号：US13461230
申请日：2012-05-01
申请人： Masaya KAWANO , Koji SOEJIMA , Nobuaki TAKAHASHI
发明人： Masaya KAWANO , Koji SOEJIMA , Nobuaki TAKAHASHI
IPC分类号： H01L23/522
CPC分类号： H01L21/76898 , H01L23/481 , H01L2224/13 , H01L2224/13025 , H01L2224/14181
摘要： A falling off of a through electrode is inhibited without decreasing a reliability of a semiconductor device including a through electrode. A semiconductor device 100 includes: a silicon substrate 101; a through electrode 129 extending through the silicon substrate 101; and a first insulating ring 130 provided in a circumference of a side surface of the through electrode 129 and extending through the semiconductor substrate 101. In addition, the semiconductor device 100 also includes a protruding portion 146, being provided at least in the vicinity of a back surface of a device-forming surface of the semiconductor substrate 101 so as to contact with the through electrode 129, and protruding in a direction along the surface of the semiconductor substrate 101 toward an interior of the through electrode 129.
摘要翻译：在不降低包括通孔的半导体器件的可靠性的情况下，抑制穿通电极的脱落。半导体器件100包括：硅衬底101; 穿过硅衬底101的通孔电极129; 以及设置在贯通电极129的侧面的周围并延伸穿过半导体基板101的第一绝缘环130.此外，半导体器件100还包括突出部分146，其设置在至少在半导体衬底101的器件形成表面的背表面与通孔129接触，并沿着半导体衬底101的表面朝向通孔129的内部突出。

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