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1. 发明申请

US20140254753A1 RADIOGRAPHIC APPARATUS AND METHOD FOR THE SAME 有权
标题翻译：放射性设备及其相关方法
公开(公告)号：US20140254753A1
公开(公告)日：2014-09-11
申请号：US13793986
申请日：2013-03-11
申请人： NOBORU YAMASHITA
发明人： NOBORU YAMASHITA
IPC分类号： A61B6/00
CPC分类号： A61B6/06 , A61B6/4233 , A61B6/5241
摘要： A radiographic apparatus detector and method therefore obtains an image having excellent recognition without the effect of body movement. A single composite image is generated by connecting strip images in the movement direction of a radiation emitter, which are extending in a direction orthogonal to an emitter movement direction. A flat panel detector (FPD) moves so that an incident radiation region in the FPD follows the shooting. A transmissive image with an improved visual recognition is obtained since shooting the strip image in the FPD is conducted by using an unused part.
摘要翻译：因此，射线照相设备检测器和方法获得具有良好识别的图像而不受身体运动的影响。通过沿着与发射器移动方向正交的方向延伸的辐射发射器的移动方向连接条带图像来生成单个合成图像。平板检测器（FPD）移动，使得FPD中的入射辐射区域跟随拍摄。获得具有改善的视觉识别的透射图像，因为通过使用未使用的部分来进行FPD中的条状图像的拍摄。

2. 发明申请

US20090257561A1 GENERAL IMAGING SYSTEM 失效
标题翻译：一般成像系统
公开(公告)号：US20090257561A1
公开(公告)日：2009-10-15
申请号：US12516116
申请日：2007-10-11
申请人： Tomoharu Okuno , Masahiro Kawano , Mikihiko Kato , Noboru Yamashita , Goro Hirata
发明人： Tomoharu Okuno , Masahiro Kawano , Mikihiko Kato , Noboru Yamashita , Goro Hirata
IPC分类号： H05G1/58 , H05G1/02 , A61B6/08
CPC分类号： A61B6/588 , A61B6/4233 , A61B6/4464 , A61B6/4476 , A61B6/467 , A61B6/545 , A61B6/547 , A61B2034/252
摘要： To automate positioning operation of an X-ray tube so as to reduce the inspection time. Anatomical program selection means selects a surgery method/imaging object portion so that an imaging condition stored as an anatomical program in advance is called out and set in an X-ray generation device. Here, when an operation switch is pressed, control means moves drive means built in X-ray irradiation means parallel movement holding means and X-ray irradiation means rotation holding means so as to obtain the positional relationship between an X-ray tube and an FPD stored in correspondence with the anatomical program (such as SID and incident angle). The position of the FPD should be matched with the examinee. However, since the positional relationship between the X-ray tube and the FPD is almost constant in accordance with the surgery method/imaging object portion, it is possible to reduce the time required for positioning the X-ray tube by using this configuration.
摘要翻译：自动化X射线管的定位操作，以减少检查时间。解剖程序选择装置选择手术方法/成像对象部分，使得在X射线产生装置中调出并设置作为解剖学程序预先存储的成像条件。这里，当按下操作开关时，控制装置移动内置在X射线照射装置平行移动保持装置和X射线照射装置旋转保持装置中的驱动装置，以获得X射线管和FPD之间的位置关系存储与解剖程序相对应（如SID和入射角）。 FPD的位置应与受检者相匹配。然而，由于X射线管和FPD之间的位置关系根据手术方法/成像对象部分几乎是恒定的，所以可以通过使用这种配置来减少定位X射线管所需的时间。

3. 发明申请

US20090116613A1 X-RAY FLUORESCENCE SPECTROMETER 有权
标题翻译： X射线荧光光谱仪
公开(公告)号：US20090116613A1
公开(公告)日：2009-05-07
申请号：US12296383
申请日：2006-11-24
申请人： Yoshiyuki Kataoka , Hisayuki Kohno , Noboru Yamashita , Makoto Doi
发明人： Yoshiyuki Kataoka , Hisayuki Kohno , Noboru Yamashita , Makoto Doi
IPC分类号： G01N23/223
CPC分类号： G01N23/223 , G01N2223/076
摘要： An X-ray fluorescence spectrometer for measuring the concentration of sulfur contained in a sample (S), by irradiating the sample (S) with primary X-rays from an X-ray tube (11), monochromating fluorescent X-rays emitted from the sample (S) with a spectroscopic device, and detecting monochromated fluorescent X-rays with an X-ray detector. The spectrometer includes the X-ray tube (11) having a target with an element including chromium, an X-ray filter (13) disposed on a path of travel of X-rays between the X-ray tube (11) and the sample (S) and having a predetermined transmittance for Cr—Kα line from the X-ray tube (11) and made of a material which is an element of which absorption edges do not exist between energies of S—Kα line and Cr—Kα line, and a proportional counter (18) having a detector gas containing a neon gas or a helium gas.
摘要翻译：一种X射线荧光光谱仪，用于通过从X射线管（11）照射样品（S）的初级X射线来测量样品（S）中所含的硫的浓度，所述X射线荧光光谱仪从样品（S），并用X射线检测器检测单色荧光X射线。光谱仪包括具有包含铬的元素的靶的X射线管（11），设置在X射线管（11）和样品之间的X射线行进路径上的X射线过滤器（13）（S），并且对于来自X射线管（11）的Cr-Kalpha线具有预定的透射率，并且由在S-Kalpha线和Cr-Kalpha线的能量之间不存在吸收边缘的元素的材料制成，以及具有包含氖气或氦气的检测器气体的比例计数器（18）。

4. 发明申请

US20070286898A1 Intracellular Drug Delivery Improving Liposome 审中-公开
标题翻译：细胞内药物递送改善脂质体
公开(公告)号：US20070286898A1
公开(公告)日：2007-12-13
申请号：US11661431
申请日：2005-08-30
申请人： Akira Takagi , Noboru Yamashita , Takashi Sonobe , Yasuyuki Sadzuka
发明人： Akira Takagi , Noboru Yamashita , Takashi Sonobe , Yasuyuki Sadzuka
IPC分类号： A61K9/127 , A61K47/32
CPC分类号： A61K9/1271 , A61K9/0019
摘要： [Problem] To provide a drug delivery system which is retained in the blood circulation and improves pharmacological effect of the drug in the target organ and cell. [Means for Resolution] A drug-containing liposome for use in the treatment with a liposome prepared by employing polyethylene glycol cholesteryl ether as a part of the liposome-forming agent and using said liposome-forming agent. It is possible to obtain excellent drug effect by further employing a polyethylene glycol diacylglycerol ester as a part of the liposome-forming agent.
摘要翻译： [问题]提供保留在血液循环中的药物递送系统，并且改善药物在靶器官和细胞中的药理作用。 [解决方法]使用通过使用聚乙二醇胆固醇醚作为脂质体形成剂的一部分并使用所述脂质体形成剂制备的用于用脂质体处理的药物含脂质体。通过进一步使用聚乙二醇二酰基甘油酯作为脂质体形成剂的一部分，可以获得优异的药物效果。

5. 发明申请

US20050054026A1 Lipid-peptide-polymer conjugates for long blood circulation and tumor specific drug delivery systems 有权
标题翻译：用于长血循环的脂质 - 肽 - 聚合物缀合物和肿瘤特异性药物递送系统
公开(公告)号：US20050054026A1
公开(公告)日：2005-03-10
申请号：US10754341
申请日：2004-01-09
申请人： Maeda Atsushi , Akira Takagi , Katsumi Saito , Noboru Yamashita , Tatsnobu Yoshioka
发明人： Maeda Atsushi , Akira Takagi , Katsumi Saito , Noboru Yamashita , Tatsnobu Yoshioka
IPC分类号： A61K9/127 , C07K7/06 , C12Q1/37 , C08G63/48 , C08G63/91
CPC分类号： C07K7/06 , A61K9/1271 , Y02P20/55
摘要： The present invention relates to conjugates of a lipid, substrate peptide of an enzyme secreted from the cells of mammals, including humans, and a water-soluble polymer that can be used as colloidal carriers and the like of tissue-specific drug delivery systems, methods of producing these conjugates, peptide-water-soluble polymer conjugates optionally having protective groups that are useful as the intermediates of these conjugates, colloidal carriers made from these conjugates, and tissue-specific drug delivery systems that use these colloidal carriers.
摘要翻译：本发明涉及从哺乳动物（包括人）的细胞分泌的酶的脂质，底物肽和可用作组织特异性药物递送系统的胶体载体等的水溶性聚合物的共轭物，方法制备这些缀合物的肽 - 水溶性聚合物缀合物，其任选地具有可用作这些缀合物的中间体的保护基，由这些缀合物制备的胶体载体，以及使用这些胶体载体的组织特异性药物递送系统。

6. 发明授权

US06328979B1 Sustained release medicinal compositions 失效
标题翻译：缓释药物组合物
公开(公告)号：US06328979B1
公开(公告)日：2001-12-11
申请号：US09582384
申请日：2000-06-23
申请人： Noboru Yamashita , Akira Takagi , Masataka Katsuma , Katsumi Saito , Yuuki Takaishi , Tatsuo Yasuda , Yutaka Takahashi , Mitsuo Mitomi
发明人： Noboru Yamashita , Akira Takagi , Masataka Katsuma , Katsumi Saito , Yuuki Takaishi , Tatsuo Yasuda , Yutaka Takahashi , Mitsuo Mitomi
IPC分类号： A61K900
CPC分类号： A61K9/0024 , A61K9/0019 , A61K9/06 , A61K31/557 , A61K31/5575 , A61K31/5585 , A61K47/10 , A61K47/12 , A61K47/14 , A61K47/186 , A61K47/20 , A61K47/36 , A61K47/42 , A61K47/44
摘要： The present invention relates to sustained-release pharmaceutical compositions for ionic pharmaceutically active substances (excluding ionic prostanoic acid derivatives) containing ionic compounds having opposite charges to those of the active substances and increasing hydrophobicity of the active substances. More specifically, the invention relates to sustained-release pharmaceutical compositions comprising the ionic pharmaceutically active substances and the ionic compounds having opposite charges to those of the active substances and increasing hydrophobicity of the active substances that contain hydrophobic groups in the molecule thereof. The pharmaceutical composition of the invention can exhibit excellent sustained release effect of the active substance, irrespective of water solubility possessed by the ionic pharmaceutically active substances.
摘要翻译：本发明涉及含有与活性物质具有相反电荷的离子化合物的离子药物活性物质（不含离子前列腺酸衍生物）的持续释放药物组合物，并且活性物质的疏水性增加。更具体地，本发明涉及包含离子药物活性物质和具有与活性物质相反的电荷的离子化合物的缓释药物组合物，并且其分子中含有疏水基团的活性物质的疏水性增加。本发明的药物组合物可以表现出优异的活性物质的缓释作用，而与离子药物活性物质所具有的水溶性无关。

7. 发明授权

US5114198A Synthetic resin bumper 失效
标题翻译：合成树脂保鲜膜
公开(公告)号：US5114198A
公开(公告)日：1992-05-19
申请号：US605951
申请日：1990-10-30
申请人： Noboru Yamashita , Keiji Sugiura , Kazunori Shimomaki , Toshiaki Takanishi
发明人： Noboru Yamashita , Keiji Sugiura , Kazunori Shimomaki , Toshiaki Takanishi
IPC分类号： B60R19/03 , B60R19/04 , B60R19/18 , B60R19/24
CPC分类号： B60R19/24 , B60R19/18
摘要： According to the present invention, there is provided a synthetic resin bumper formed by fitting a resin made absorber having an enclosed cross section structure which is covered with a facing of a separate body to a car body by a pair of right and left brackets disposed on a rear face side thereof, wherein a flange is provided at a front end portion of each of above-mentioned brackets, and through holes formed by a side wall which reaches from a front face to a rear face are provided at portions of the absorber located within a scope where this flange is disposed.
摘要翻译：根据本发明，提供了一种合成树脂保险杠，该合成树脂保险杠通过将具有封闭横截面结构的树脂制吸收体装配成一个由左右托架组成的一对单独的主体的面，其背面侧，其中在上述支架的前端部设置有凸缘，在从所述吸收体的位置的部分设置有从前面到后面到达的侧壁形成的通孔在该法兰被设置的范围内。

8. 发明申请

US20080121093A1 KEYBOARD MUSICAL INSTRUMENT HAVING KEYS EQUIPPED WITH BALANCERS BITING INTO KEYS AND METHOD FOR SECURING BALANCERS TO KEYS 有权
标题翻译：带平衡键的键盘键盘乐器和用于保持平衡键的方法
公开(公告)号：US20080121093A1
公开(公告)日：2008-05-29
申请号：US11942982
申请日：2007-11-20
申请人： Hitoshi Izutani , Noboru Yamashita , Satoshi Inoue
发明人： Hitoshi Izutani , Noboru Yamashita , Satoshi Inoue
IPC分类号： G10H1/34
CPC分类号： G10C3/12
摘要： Keys of an acoustic piano require balancers for cancellation of a part of self weight of the action units/hammers; however, the balancers are liable to be dropped off due to the aged deterioration of the wooden bars; in order to keep the balancers stable in the keys against the aged deterioration, the balancer is plastically deformed so as to bite into the wooden bar, the balancer, which is formed with thorns, is rotated so as to make the thorns bite into the wooden bar, the balancer is shaped into a configuration different from the holes so as to exert resilient force on the inner surface in a direction in parallel to the grain of wood, or the balancer is inserted into a constricted hole so as to strongly exert the resilient force on the inner surface, thereby being prevented from the dropping off from the keys.
摘要翻译：原声钢琴的钥匙需要平衡器来取消动作单元/锤的自重的一部分; 然而，平衡机由于木条老化而易于脱落; 为了保持平衡器在老化过程中的平衡器稳定，平衡器被塑性变形，以便咬入木条中，形成有刺的平衡器被旋转以使荆棘咬入木制平衡器成形为不同于孔的构造，以在平行于木纹的方向上在内表面上施加弹性力，或者将平衡器插入收缩孔中，以便强力地施加弹性在内表面上的力，从而防止从键脱落。

9. 发明授权

US06919372B1 Sustained release pharmaceutical compositions 失效
标题翻译：持续释放药物组合物
公开(公告)号：US06919372B1
公开(公告)日：2005-07-19
申请号：US09582404
申请日：1998-12-25
申请人： Noboru Yamashita , Akira Takagi , Masataka Katsuma , Katsumi Saito , Yuuki Takaishi , Tatsuo Yasuda , Yutaka Takahashi , Mitsuo Mitomi , Michio Hara
发明人： Noboru Yamashita , Akira Takagi , Masataka Katsuma , Katsumi Saito , Yuuki Takaishi , Tatsuo Yasuda , Yutaka Takahashi , Mitsuo Mitomi , Michio Hara
IPC分类号： A61K9/00 , A61K9/06 , A61K31/557 , A61K31/5575 , A61K31/5585 , A61K47/10 , A61K47/12 , A61K47/14 , A61K47/18 , A61K47/20 , A61K47/36 , A61K47/42 , A61K47/44 , A01N43/08 , A61K31/34
CPC分类号： A61K9/0024 , A61K9/0019 , A61K9/06 , A61K31/557 , A61K31/5575 , A61K31/5585 , A61K47/10 , A61K47/12 , A61K47/14 , A61K47/186 , A61K47/20 , A61K47/36 , A61K47/42 , A61K47/44
摘要： The present invention relates to sustained-release pharmaceutical compositions for ionic pharmaceutically active substances containing ionic compounds having opposite charges to those of ionic prostanoic acid derivatives and increasing hydrophobicity of the active substances. More specifically, the invention relates to sustained-release pharmaceutical compositions comprising the ionic prostanoic acid derivatives and the ionic compounds having opposite charges to those of the prostanoic acid derivatives and increasing hydrophobicity of these derivatives that contain hydrophobic groups in the molecule thereof.The pharmaceutical composition of the invention can exhibit excellent sustained release effect of the ionic prostanoic acid derivatives, irrespective of water solubility possessed by the ionic prostanoic acid derivatives.
摘要翻译：本发明涉及含离子化合物的离子药物活性物质的缓释药物组合物，其具有与离子前列腺酸衍生物相反的电荷并增加活性物质的疏水性。更具体地，本发明涉及包含离子前列腺酸衍生物和具有与前列腺酸衍生物相反电荷的离子化合物的缓释药物组合物，并且在其分子中含有疏水基团的这些衍生物的疏水性增加。本发明的药物组合物可以表现出优异的离子前列腺酸衍生物的缓释作用，而与离子前列腺酸衍生物具有的水溶性无关。

10. 发明授权

US06745730B2 Odd-cylinder v-type internal combustion engine 失效
标题翻译：异缸V型内燃机
公开(公告)号：US06745730B2
公开(公告)日：2004-06-08
申请号：US10204255
申请日：2002-08-19
申请人： Noboru Yamashita
发明人： Noboru Yamashita
IPC分类号： F02B7522
CPC分类号： F02B75/22 , F02B61/02 , F02B2075/025 , F02B2075/1804 , F02B2075/182 , F16F15/24 , F16F15/283
摘要： An odd-cylinder V-type internal combustion engine including 2n+1 cylinders (n is a natural number) arranged in two banks and pistons fitted in the cylinders has a crankshaft provided with n common crankpins (KC) each connected to the two paired pistons respectively belonging to the two banks, and one odd crankpin (KS) connected to the one unpaired piston. The common crankpins (KC) are disposed at the same phase. Bank angle &thgr; between the two banks meets &thgr;=cos−1(½n). The odd crankpin (KS) is disposed (180−&thgr;)° behind the common crank pins (KC) with respect to the rotating direction of the crankshaft when the unpaired piston belongs to the front bank with respect to the rotating direction of the crankshaft. Reciprocating parts including all the pistons fitted in the cylinders have the same mass (M), and the crankshaft is provided with balance weight means capable of generating a balancing force of kMr&ohgr;2 acting in a sense of (&agr;+180)°, where: k = ( 1 2 ⁢ 1 - 1 4 ⁢ n 2 ) 2 + ( n - 1 4 ⁢ n ) 2 α = sin - 1 ( 1 2 ⁢ 1 - 1 4 ⁢ n 2 k ) &agr;: Angle from the common crankpins in the rotating direction M: Mass of each reciprocating part r: Crank throw &ohgr;: Angular velocity of the crankshaft The odd-cylinder V-type internal combustion engine prevents generation of a primary vibration caused by a primary inertial force without entailing increase in weight and size.
摘要翻译：配置在两个缸体中的2n + 1个气缸（n为自然数）的奇数气缸V型内燃机，配有气缸的活塞具有设置有n个共同曲柄销的曲轴，分别属于两组的活塞和连接到一个未配套活塞的一个奇数曲柄销。常见的曲柄销布置在同一相位。两组之间的倾斜角θθ= cos（-1）（½n）。当不匹配的活塞相对于曲轴的旋转方向属于前排时，奇曲柄销相对于曲轴的旋转方向设置在公共曲柄销的后面（180度）。包括安装在气缸中的所有活塞的往复部件具有相同的质量（M），并且曲轴设置有能够产生以（α+ 180）°的方式起作用的kMromega 2的平衡力的平衡重，其中：α：旋转方向上共用曲柄销的角度M：往复运动部件的质量曲轴转速：曲轴的角速度奇数缸V型内燃机可防止主要惯性力产生的主振动，而不需要重量和尺寸增加。

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