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1. 发明申请

US20110105865A1 DIFFUSE REFLECTANCE SPECTROSCOPY DEVICE FOR QUANTIFYING TISSUE ABSORPTION AND SCATTERING 审中-公开
标题翻译：用于定量组织吸收和散射的折射率反射光谱装置
公开(公告)号：US20110105865A1
公开(公告)日：2011-05-05
申请号：US12989595
申请日：2009-04-24
申请人： Bing Yu , Nimala Ramanujan , Justin Y. Lo
发明人： Bing Yu , Nimala Ramanujan , Justin Y. Lo
IPC分类号： A61B5/1455
CPC分类号： A61B5/0059
摘要： A diffuse reflectance spectroscopy system for quantifying electromagnetic absorption and scattering in a tissue is provided. Also provided are optical probes and methods for imaging a tissue mass. In some embodiments, the methods include the steps of contacting a tissue mass with an optical probe, wherein the optical probe includes at least one entity for emitting light that interacts with a tissue mass and then is remitted to a collecting entity, for collecting the light that has interacted with the tissue mass, wherein the collecting entity comprises a detector comprising one or more photodiodes; measuring turbid spectral data of the tissue mass using the optical probe; converting the turbid spectral data to at least one of absorption and scattering spectral data via a Monte Carlo algorithm or a diffusion algorithm; and quantifying tissue compositions and scatterer size in a tissue mass using the at least one of absorption and scattering spectral data.
摘要翻译：提供了用于量化组织中的电磁吸收和散射的漫反射光谱系统。还提供了用于成像组织块的光学探针和方法。在一些实施例中，所述方法包括使组织块与光学探针接触的步骤，其中所述光学探针包括用于发射与组织块相互作用的光的至少一个实体，然后被传送到收集实体，用于收集光其与所述组织块相互作用，其中所述收集实体包括检测器，所述检测器包括一个或多个光电二极管; 使用光学探针测量组织块的混浊光谱数据; 通过蒙特卡罗算法或扩散算法将混浊光谱数据转换成吸收和散射光谱数据中的至少一个; 以及使用吸收和散射光谱数据中的至少一个来定量组织块中的组织组成和散射体大小。

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