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1. 发明授权

US10550366B2 Thermoresponsive cell culture supports 有权
公开(公告)号：US10550366B2
公开(公告)日：2020-02-04
申请号：US15499964
申请日：2017-04-28
申请人： Bi-Min Newby , Nikul Patel , John Cavicchia , Ge Zhang
发明人： Bi-Min Newby , Nikul Patel , John Cavicchia , Ge Zhang
IPC分类号： C12N5/00 , C12N5/0775
摘要： The present invention relates to a cell culture support including a substrate and a thermoresponsive polymeric blend layer, wherein the polymeric blend layer includes at least one thermoresponsive polymer and at least one network forming adhesion promoter. The present invention further relates a method of making a cell culture complex including: providing a substrate; blending at least one thermoresponsive polymer and at least one network forming adhesion promoter to provide a polymeric blend; applying a thin film of said polymeric blend to the substrate to provide a polymeric blend layer on the substrate; curing the polymeric blend layer on the substrate to provide a cell culture support; and depositing cells onto said cell culture support, wherein the cells may optionally further include medium, to provide a cell culture complex.

2. 发明申请

US20170260497A1 THERMORESPONSIVE CELL CULTURE SUPPORTS 审中-公开
公开(公告)号：US20170260497A1
公开(公告)日：2017-09-14
申请号：US15499964
申请日：2017-04-28
申请人： Bi-Min Newby , Nikul Patel , John Cavicchia , Ge Zhang
发明人： Bi-Min Newby , Nikul Patel , John Cavicchia , Ge Zhang
IPC分类号： C12N5/00 , C12N5/0775
CPC分类号： C12N5/0068 , C12N5/0662 , C12N5/0663 , C12N5/0664 , C12N5/0665 , C12N5/0666 , C12N5/0667 , C12N5/0668 , C12N2533/12 , C12N2539/10
摘要： The present invention relates to a cell culture support including a substrate and a thermoresponsive polymeric blend layer, wherein the polymeric blend layer includes at least one thermoresponsive polymer and at least one network forming adhesion promoter. The present invention further relates a method of making a cell culture complex including: providing a substrate; blending at least one thermoresponsive polymer and at least one network forming adhesion promoter to provide a polymeric blend; applying a thin film of said polymeric blend to the substrate to provide a polymeric blend layer on the substrate; curing the polymeric blend layer on the substrate to provide a cell culture support; and depositing cells onto said cell culture support, wherein the cells may optionally further include medium, to provide a cell culture complex.

3. 发明授权

US07255439B1 Eye diversion assembly and method 失效
标题翻译：眼睛分流装配及方法
公开(公告)号：US07255439B1
公开(公告)日：2007-08-14
申请号：US11232144
申请日：2005-09-22
申请人： Nikul Patel
发明人： Nikul Patel
IPC分类号： A61B3/00
CPC分类号： A61H5/00 , A61B3/032
摘要： An eye diversion assembly includes a base that has a top wall, a bottom wall and a perimeter wall. A pair of supports extends upwardly from the top wall. An axle is rotatably coupled to and extends between the supports. The axle extends through a plurality of panels. The axle extends through a central area of each of the panels. At least one of the panels is fixedly coupled to the axle and at least one of the panels is rotatably coupled to the axle. Each of a plurality of magnets is attached to one of the panels. A drive assembly mounted in the base is mechanically coupled to the axle. The drive assembly is configured to selectively rotate the axle. A power supply is electrically coupled to the drive assembly. A person's eyes are diverted toward the panels when the drive assembly is turned on.
摘要翻译：眼睛转移组件包括具有顶壁，底壁和周边壁的基部。一对支撑件从顶壁向上延伸。轴可旋转地联接到支撑件之间并在支撑件之间延伸。轴延伸穿过多个面板。轴延伸穿过每个面板的中心区域。至少一个面板固定地联接到轴上，并且至少一个面板可旋转地联接到轴。多个磁体中的每一个都附接到一个面板。安装在基座中的驱动组件机械地联接到轴上。驱动组件构造成选择性地旋转轴。电源电耦合到驱动组件。当驱动器组件打开时，人的眼睛转向面板。

4. 发明授权

US09701939B2 Thermoresponsive cell culture supports 有权
公开(公告)号：US09701939B2
公开(公告)日：2017-07-11
申请号：US14110465
申请日：2012-04-06
申请人： Bi-Min Newby , Nikul Patel , John Cavicchia , Ge Zhang
发明人： Bi-Min Newby , Nikul Patel , John Cavicchia , Ge Zhang
IPC分类号： C12N5/0775 , C12N5/00
CPC分类号： C12N5/0068 , C12N5/0662 , C12N5/0663 , C12N5/0664 , C12N5/0665 , C12N5/0666 , C12N5/0667 , C12N5/0668 , C12N2533/12 , C12N2539/10
摘要： The present invention relates to a cell culture support comprising a substrate and a thermoresponsive polymeric blend layer, wherein the polymeric blend layer comprises at least one thermoresponsive polymer and at least one network forming adhesion promoter. The present invention further relates a method of making a cell culture complex comprising: providing a substrate; blending at least one thermoresponsive polymer and at least one network forming adhesion promoter to provide a polymeric blend; applying a thin film of said polymeric blend to the substrate to provide a polymeric blend layer on the substrate; curing the polymeric blend layer on the substrate to provide a cell culture support; and depositing cells onto said cell culture support, wherein the cells may optionally further comprise medium, to provide a cell culture complex.

5. 发明授权

US09183208B1 Fileshot management 有权
标题翻译：文件管理
公开(公告)号：US09183208B1
公开(公告)日：2015-11-10
申请号：US12978444
申请日：2010-12-24
申请人： Anuja Jaiswal , Nikul Patel , Devang K. Shah
发明人： Anuja Jaiswal , Nikul Patel , Devang K. Shah
IPC分类号： G06F17/30 , G06F11/14
CPC分类号： G06F11/1458 , G06F11/1446 , G06F11/1448 , G06F11/1451 , G06F17/30067 , G06F17/3007 , G06F17/30088 , G06F17/3023 , G06F2201/84
摘要： Many applications and computing environments, such as data storage systems, provide data backup and restoration features. It may be advantageous to provide file level backups that may be accessible to a user through a directory structure of a file system. Accordingly, fileshots comprising backup data of a file may be stored as metadata of the file. For example, a fileshot may be stored within a stream directory as a hidden stream linked off of the file. Fileshots may be associated within a directory interface (e.g., a command prompt or graphical user interface), which may be presented to a user. In this way, the user may access and/or manage fileshots through the directory interface (e.g., the user may create fileshots, restore files with fileshots, copy fileshots, etc.). Additionally, fileshot metadata may be maintained for fileshots. The fileshot metadata may be used to locate fileshot and/or perform fileshot commands.
摘要翻译：许多应用程序和计算环境（如数据存储系统）可提供数据备份和恢复功能。提供可以通过文件系统的目录结构对用户可访问的文件级备份可能是有利的。因此，包括文件的备份数据的文件截图可以被存储为文件的元数据。例如，文件照片可以作为从文件关联的隐藏流存储在流目录中。文件截图可以在可以呈现给用户的目录界面（例如，命令提示符或图形用户界面）中相关联。以这种方式，用户可以通过目录界面访问和/或管理文件截图（例如，用户可以创建文件截图，使用文件快照恢复文件，复制文件截图等）。此外，可以维护文件照片元数据。文件照片元数据可用于定位文件和/或执行文件照片命令。

6. 发明申请

US20140193911A1 THERMORESPONSIVE CELL CULTURE SUPPORTS 有权
标题翻译：热源细胞培养支持
公开(公告)号：US20140193911A1
公开(公告)日：2014-07-10
申请号：US14110465
申请日：2012-04-06
申请人： Bi-Min Newby , Nikul Patel , John Cavicchia , Ge Zhang
发明人： Bi-Min Newby , Nikul Patel , John Cavicchia , Ge Zhang
IPC分类号： C12N5/00 , C12N5/0775
CPC分类号： C12N5/0068 , C12N5/0662 , C12N5/0663 , C12N5/0664 , C12N5/0665 , C12N5/0666 , C12N5/0667 , C12N5/0668 , C12N2533/12 , C12N2539/10
摘要： The present invention relates to a cell culture support comprising a substrate and a thermoresponsive polymeric blend layer, wherein the polymeric blend layer comprises at least one thermoresponsive polymer and at least one network forming adhesion promoter. The present invention further relates a method of making a cell culture complex comprising: providing a substrate; blending at least one thermoresponsive polymer and at least one network forming adhesion promoter to provide a polymeric blend; applying a thin film of said polymeric blend to the substrate to provide a polymeric blend layer on the substrate; curing the polymeric blend layer on the substrate to provide a cell culture support; and depositing cells onto said cell culture support, wherein the cells may optionally further comprise medium, to provide a cell culture complex.
摘要翻译：本发明涉及一种细胞培养载体，其包括基质和热反应性聚合物共混物层，其中所述聚合共混物层包含至少一种热响应聚合物和至少一种形成网络的粘合促进剂。本发明还涉及一种制备细胞培养复合物的方法，包括：提供底物; 混合至少一种热可聚合物和至少一种形成网络的粘合促进剂以提供聚合物共混物; 将所述聚合物共混物的薄膜施加到所述基底上以在所述基底上提供聚合物共混物层; 固化基底上的聚合物共混物层以提供细胞培养支持物; 以及将细胞沉积在所述细胞培养支持物上，其中所述细胞可以任选地进一步包含培养基，以提供细胞培养物复合物。

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