专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US07018640B2 In ovo vaccination against coccidiosis 失效
公开(公告)号：US07018640B2
公开(公告)日：2006-03-28
申请号：US10094436
申请日：2002-03-08
申请人： Nigel A. Evans , Robert Craig Findly , Frederick H. Weber
发明人： Nigel A. Evans , Robert Craig Findly , Frederick H. Weber
IPC分类号： A61K39/00 , A61K39/38 , A61K39/012 , A61K39/002 , A61K39/008
CPC分类号： A61K39/012 , A61K2039/51 , A61K2039/522 , A61K2039/55
摘要： The invention relates to a method of vaccinating a domesticated bird against coccidiosis comprising administering in ovo an effective immnunizing dose of live Eimeria sporozoites or merozoites, or a mixture thereof. In a preferred embodiment, the domesticated bird that is vaccinated is a chicken or turkey.

2. 发明授权

US06608033B1 Treatment or prevention of coccidiosis 失效
标题翻译：治疗或预防球虫病
公开(公告)号：US06608033B1
公开(公告)日：2003-08-19
申请号：US09630045
申请日：2000-08-01
申请人： Peter C. Canning , Renee L. Hassfurther , Nigel A. Evans
发明人： Peter C. Canning , Renee L. Hassfurther , Nigel A. Evans
IPC分类号： A61K3170
CPC分类号： A61K31/7052 , A61K31/70
摘要： Coccidiosis in a bovine animal is prevented by administration of an effective amount of a macrolide antibiotic.
摘要翻译：通过施用有效量的大环内酯类抗生素来防止牛动物中的球虫病。

3. 发明授权

US06506785B2 Treating or preventing the early stages of degeneration of articular cartilage or subchondral bone in mammals using carprofen and derivatives 失效
公开(公告)号：US06506785B2
公开(公告)日：2003-01-14
申请号：US09283993
申请日：1999-04-01
申请人： Nigel A. Evans , Carolyn R. Kilroy , Kristin M. Lundy , Jean-Pierre Pelletier , Anthony P. Ricketts
发明人： Nigel A. Evans , Carolyn R. Kilroy , Kristin M. Lundy , Jean-Pierre Pelletier , Anthony P. Ricketts
IPC分类号： A61K3140
CPC分类号： A61K31/405
摘要： Treating or preventing the early stages of degeneration of articular cartilage or subchondral bone in the affected joint of a mammal is accomplished by administering a chondroprotective compound of Formula (I): where A is hydroxy, (C1-C4)alkoxy, amino, hydroxy-amino, mono-(C1-C2)alkylamino, di-(C1-C2)alkylamino; X and Y are independently H or (C1-C2)alkyl; and n is 1 or 2; R6 is halogen, (C1-C3)alkyl, trifluoromethyl, or nitro; R9 is H; (C1-C2)alkyl; phenyl or phenyl-(C1-C2)alkyl, where phenyl is optionally mono-substituted by fluoro or chloro; —C(═O)—R, where R is (C1-C2)alkyl or phenyl, optionally mono-substituted by fluoro or chloro; or —C(═O)—O—R′, where R1 is (C1-C2)alkyl. This treatment ameliorates, diminishes, actively treats, reverses or prevents any injury, damage or loss of articular cartilage or subchondral bone subsequent to said early stage of said degeneration. Whether or not a mammal needs such treatment is determined by whether or not it exhibits a statistically significant deviation from normal standard values in synovial fluid or membrane from the affected joint, with respect to at least five of the following substances: increased interleukin-1 beta (IL-1&bgr;); increased tumor necrosis factor alpha (TNF&agr;); increased ratio of IL-1&bgr; to IL-1 receptor antagonist protein (IRAP); increased expression of p55 TNF receptors (p55 TNF-R); increased interleukin-6 (IL-6); increased leukemia inhibitory factor (LIF); decreased insulin-like growth factor-1 (IGF-1); decreased transforming growth factor beta (TGF&bgr;); decreased platelet-derived growth factor (PDGF); decreased basic fibroblast growth factor (b-FGF); increased keratan sulfate; increased stromelysin; increased ratio of stromelysin to tissue inhibitor of metalloproteases (TIMP); increased osteocalcin; increased alkaline phosphatase; increased cAMP responsive to hormone challenge; increased urokinase plasminogen activator (uPA); increased cartilage oligomeric matrix protein; and increased collagenase.

4. 发明授权

US06500438B2 In ovo vaccination against coccidiosis 失效
标题翻译：卵巢疫苗接种抗球虫病
公开(公告)号：US06500438B2
公开(公告)日：2002-12-31
申请号：US08973133
申请日：1997-12-01
申请人： Nigel A. Evans , Robert Craig Findly , Frederick H. Weber
发明人： Nigel A. Evans , Robert Craig Findly , Frederick H. Weber
IPC分类号： A61K39012
CPC分类号： A61K39/012 , A61K2039/51 , A61K2039/522 , A61K2039/55
摘要： The invention relates to a method of vaccinating a domesticated bird against coccidiosis comprising administering in ovo an effective immunizing dose of live Eimeria sporozoites or merozoites, or a mixture thereof. In a preferred embodiment, the domesticated bird that is vaccinated is a chicken or turkey.
摘要翻译：本发明涉及一种针对球虫病接种家禽的方法，其中包括以卵内施用有效免疫剂量的活艾美球虫子孢子或裂殖子或其混合物。在优选的实施方案中，被接种的驯养的鸟是鸡或火鸡。

5. 发明授权

US06495146B1 In ovo vaccination against coccidiosis 失效
公开(公告)号：US06495146B1
公开(公告)日：2002-12-17
申请号：US08973151
申请日：1997-12-01
申请人： Nigel A. Evans , Robert Craig Findly , Frederick H. Weber
发明人： Nigel A. Evans , Robert Craig Findly , Frederick H. Weber
IPC分类号： A61K3900
CPC分类号： A61K39/012
摘要： The invention relates to a method of vaccinating a domesticated bird against coccidiosis comprising administering in ovo an effective immunizing dose of live Eimeria sporocysts or oocysts, or a mixture thereof.

6. 发明授权

US06627205B2 Ovo vaccination against coccidiosis 有权
标题翻译： Ovo接种抗球虫病
公开(公告)号：US06627205B2
公开(公告)日：2003-09-30
申请号：US10094087
申请日：2002-03-08
申请人： Nigel A. Evans , Robert Craig Findly , Frederick H. Weber
发明人： Nigel A. Evans , Robert Craig Findly , Frederick H. Weber
IPC分类号： A61K39012
CPC分类号： A61K39/012 , A61K2039/52 , A61K2039/54
摘要： The invention relates to a method of vaccinating a domesticated bird against coccidiosis comprising administering in ovo an effective immunizing dose of live Eimeria sporocysts or oocysts, or a mixture thereof.
摘要翻译：本发明涉及一种针对球虫病接种驯养的禽类的方法，其包括在卵内施用有效免疫剂量的活艾美球虫孢子囊或卵囊或其混合物。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式