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1. 发明申请

US20140004244A1 Taste-Masking Compositions, Sweetener Compositions and Consumable Product Compositions Containing the Same 有权
标题翻译：味道掩蔽组合物，甜味剂组合物和含有其的消费品组合物
公开(公告)号：US20140004244A1
公开(公告)日：2014-01-02
申请号：US13630384
申请日：2012-09-28
申请人： NUTRINOVA NUTRITION SPECIALTIES & FOOD INGREDIENTS
发明人： Clemens M. Putter , Johann Wonschik
IPC分类号： A23L1/227 , A23L2/60 , A23L1/236 , A23C9/156
CPC分类号： A23L1/053 , A23G1/32 , A23G3/36 , A23G4/06 , A23G9/32 , A23L2/56 , A23L2/60 , A23L5/00 , A23L27/30 , A23L27/31 , A23L27/33 , A23L27/34 , A23L27/35 , A23L27/37 , A23L27/39 , A23L27/84 , A23L27/86 , A23L29/25 , A23L29/30 , A23L29/35 , A23L29/37 , A23V2002/00 , A23V2200/15 , A23V2200/16 , A23V2250/06 , A23V2250/21162 , A23V2250/24 , A23V2250/5028 , A23V2250/5114
摘要： The present invention relates to novel compositions X comprising following substances: (1) L-valine; (2) maltol; (3) naringin; (4) maltodextrine MD 14 (5) arabicgum (spraygum); (6) acetoin; (7) delta dodecalactone; (8) delta decalactone; and (9) massoia lactone.
摘要翻译：本发明涉及包含以下物质的新型组合物X：（1）L-缬氨酸; （2）麦芽糖（3）柚皮苷; （4）麦芽糊精MD 14（5）阿拉伯胶（spraygum）; （6）乙偶姻; （7）δ十二内酯; （8）三角癸内酯; 和（9）土质内酯。

2. 发明申请

US20130210046A1 SCREENING METHODS FOR COMPOUNDS THAT MODULATE THE ACTIVITY OF G-PROTEIN COUPLED RECEPTORS 审中-公开
标题翻译：调节G蛋白偶联受体活性的化合物的筛选方法
公开(公告)号：US20130210046A1
公开(公告)日：2013-08-15
申请号：US13829318
申请日：2013-03-14
申请人： Nutrinova Nutrition Specialties & Food Ingredients GmbH
发明人： Michael KROHN , Holger Zinke
IPC分类号： C12Q1/02
CPC分类号： C12Q1/025 , C12N15/79 , G01N33/566 , G01N2333/705 , G01N2500/10
摘要： The present invention relates to a screening system for modulators of GPCRs. Further it relates to recombinant vector systems for the heterologous expression of heterodimeric G-protein coupled receptors (GPCRs) in eukaryotic host cells. Preferably the functional expression of engineered GPCRs for the perception of sweet and L-amino acid taste or more preferably the use of these receptors for the identification of functional ligands is also encompassed.
摘要翻译：本发明涉及一种用于GPCR调制器的筛选系统。此外，它涉及异源二聚体G蛋白偶联受体（GPCR）在真核宿主细胞中异源表达的重组载体系统。优选地，还包括用于感知甜和L-氨基酸味道的工程化GPCR的功能性表达或更优选地使用这些受体用于鉴定功能性配体。

3. 发明授权

US09024016B2 Process for producing acesulfame potassium 有权
标题翻译：生产乙酰磺胺酸钾的方法
公开(公告)号：US09024016B2
公开(公告)日：2015-05-05
申请号：US13901735
申请日：2013-05-24
申请人： Nutrinova Nutrition Specialties & Food Ingredients GmbH
发明人： Michael J. Bayer , Stephan Brietzke , Peter Groer , Christoph Mollenkopf
IPC分类号： C07D291/06 , C07D307/02 , A23L1/236 , C07C307/02
CPC分类号： A23L1/236 , A23L27/30 , C07C307/02 , C07D291/06
摘要： In one embodiment, the invention relates to processes for producing acesulfame potassium. In one embodiment, the process comprises the step of reacting a first reaction mixture to form an amidosulfamic acid salt such as a trialkyl ammonium amidosulfamic acid salt. The first reaction mixture comprises sulfamic acid, an amine, and smaller amounts, if any, acetic acid, e.g., less than 1 wt % (10000 wppm). In terms of ranges, the first reaction mixture may comprise from 1 wppm to 1 wt % acetic acid. The process further comprises the step of reacting the amidosulfamic acid salt with diketene to form an acetoacetamide salt. In preferred embodiments, the amidosulfamic acid salt formation reaction is conducted at pH levels from 5.5 to 7.0. The process further comprises the step of deriving the acesulfame-K from the acetoacetamide salt.
摘要翻译：在一个实施方案中，本发明涉及生产乙酰磺胺酸钾的方法。在一个实施方案中，该方法包括使第一反应混合物反应形成氨基磺酰胺酸盐如氨基磺酰胺酸三烷基铵盐的步骤。第一反应混合物包含氨基磺酸，胺和少量（如果有的话）乙酸，例如小于1重量％（10000wppm））。就范围而言，第一反应混合物可以包含1wppm至1wt％的乙酸。该方法还包括使氨基磺酰胺酸盐与双烯酮反应形成乙酰乙酰胺盐的步骤。在优选的实施方案中，氨基磺酰胺酸盐形成反应在5.5至7.0的pH水平下进行。该方法还包括从乙酰乙酰胺盐衍生乙酰磺胺酸K的步骤。

4. 发明授权

US09138011B2 Taste-masking compositions, sweetener compositions and consumable product compositions containing the same 有权
标题翻译：味道掩蔽组合物，甜味剂组合物和含有它们的消费品组合物
公开(公告)号：US09138011B2
公开(公告)日：2015-09-22
申请号：US13630384
申请日：2012-09-28
申请人： Nutrinova Nutrition Specialties & Food Ingredients GmbH
发明人： Clemens M. Putter , Johann Wonschik
IPC分类号： A23L1/227 , A23L1/053 , A23L2/56 , A23L2/60 , A23L1/22 , A23L1/236 , A23L1/09 , A23G1/32 , A23G3/36 , A23G4/06 , A23G9/32
CPC分类号： A23L1/053 , A23G1/32 , A23G3/36 , A23G4/06 , A23G9/32 , A23L2/56 , A23L2/60 , A23L5/00 , A23L27/30 , A23L27/31 , A23L27/33 , A23L27/34 , A23L27/35 , A23L27/37 , A23L27/39 , A23L27/84 , A23L27/86 , A23L29/25 , A23L29/30 , A23L29/35 , A23L29/37 , A23V2002/00 , A23V2200/15 , A23V2200/16 , A23V2250/06 , A23V2250/21162 , A23V2250/24 , A23V2250/5028 , A23V2250/5114
摘要： The present invention relates to novel compositions X comprising following substances: (1) L-valine; (2) maltol; (3) naringin; (4) maltodextrine MD 14 (5) arabicgum (spraygum); (6) acetoin; (7) delta dodecalactone; (8) delta decalactone; and (9) massoia lactone.
摘要翻译：本发明涉及包含以下物质的新型组合物X：（1）L-缬氨酸; （2）麦芽糖（3）柚皮苷; （4）麦芽糊精MD 14（5）阿拉伯胶（spraygum）; （6）乙偶姻; （7）δ十二内酯; （8）三角癸内酯; 和（9）土质内酯。

5. 发明申请

US20130136839A1 Taste-Masking Compositions, Sweetener Compositions and Consumable Product Compositions Containing the Same 审中-公开
标题翻译：味道掩蔽组合物，甜味剂组合物和含有其的消费品组合物
公开(公告)号：US20130136839A1
公开(公告)日：2013-05-30
申请号：US13630341
申请日：2012-09-28
申请人： Nutrinova Nutrition Specialties & Food Ingredients
发明人： Clemens M. Putter , Johann Wonschik
IPC分类号： A23L1/236
CPC分类号： A23L29/30 , A23L5/00 , A23L7/00 , A23L9/00 , A23L21/00 , A23L27/30 , A23L27/31 , A23L27/37 , A23L27/84 , A23L27/86 , A23L29/35 , A23L29/37 , A23L33/125
摘要： In one embodiment, the present invention relates to a sweetener composition comprising: a sweetener and at least one flavoring. The at least one flavoring is suitable for modifying, masking, reducing and/or suppressing an unpleasant off-taste of the sweetener in a consumable product composition formed by adding the sweetener composition to a consumable product. A weight ratio of the at least one flavoring to the sweetener in the consumable product composition is such that the sweetness of the sweetener is detectable by taste in the consumable product composition and the flavor of the at least one flavoring is not detectable by taste in the consumable product composition.
摘要翻译：在一个实施方案中，本发明涉及甜味剂组合物，其包含甜味剂和至少一种调味剂。所述至少一种调味剂适合于通过将甜味剂组合物添加到消费品中而形成的消费产品组合物中，改善，掩蔽，还原和/或抑制甜味剂不愉快的味道。可消费产品组合物中的至少一种调味剂与甜味剂的重量比使得甜味剂的甜度可通过消费产品组合物中的味道检测，并且至少一种调味剂的风味在消耗品组成。

6. 发明申请

US20130136836A1 Taste-Masking Compositions, Sweetener Compositions and Consumable Product Compositions Containing the Same 审中-公开
标题翻译：味道掩蔽组合物，甜味剂组合物和含有其的消费品组合物
公开(公告)号：US20130136836A1
公开(公告)日：2013-05-30
申请号：US13630254
申请日：2012-09-28
申请人： Nutrinova Nutrition Specialties & Food Ingredients
发明人： Clemens M. Putter , Johann Wonschik
IPC分类号： A23L1/22 , A23C9/156 , A23L2/60 , A23L1/236
CPC分类号： A23L29/30 , A23L5/00 , A23L7/00 , A23L9/00 , A23L21/00 , A23L27/30 , A23L27/31 , A23L27/37 , A23L27/84 , A23L27/86 , A23L29/35 , A23L29/37 , A23L33/125
摘要： The present invention in one aspect, relates to a composition X comprising the following substances: at least one bitter blocking agent; at least one carbonyl compound; and at least one lactone.
摘要翻译：本发明一方面涉及包含以下物质的组合物X：至少一种苦味剂; 至少一种羰基化合物; 和至少一种内酯。

7. 发明申请

US20150104557A1 METHOD FOR THE CULTIVATION OF MICROORGANISMS OF THE GENUS THRAUSTOCHYTRIALES BY USING AN OPTIMIZED LOW SALT MEDIUM 审中-公开
标题翻译：通过使用优化的低盐培养基来培养基因组织微生物的方法
公开(公告)号：US20150104557A1
公开(公告)日：2015-04-16
申请号：US14525315
申请日：2014-10-28
申请人： Nutrinova Nutrition Specialties & Food Ingredients GMBH
发明人： Matthias Rusing , Markus Luy
IPC分类号： C12P7/64 , A23K1/14 , A23L1/30
CPC分类号： C12P7/6427 , A23K10/37 , A23L33/12 , A23V2002/00 , C12N1/12 , C12P7/6472
摘要： The invention relates to an optimized method for cultivating microorganisms of the genus Thraustochytriales, according to which the microorganisms are cultivated in a low salt medium without adding sodium salts and chloride salts, the total salt content being less than 3.5 g/L (corresponding to less than 10 percent of sea water salt content), whereupon the PUFAs are isolated from the microorganisms and/or the medium. The invention especially relates to novel optimized media having a substantially reduced total salt content, above all a particularly reduced NaCl content. The production of PUFAs can be substantially improved and significantly simplified by using a novel combination of different salts as a media composition in which the overall weight ratios of ions do not exceed 1.75 g/L. Furthermore, said medium preferably contains no added sodium salt and chloride salt at all, which helps prevent environmental damages caused by wastewaters containing salt.
摘要翻译：本发明涉及一种用于培养破囊壶菌属微生物的优化方法，根据该方法，微生物在低盐培养基中培养而不添加钠盐和氯化物盐，总盐含量小于3.5g / L（相当于少于超过10％的海水盐含量），由此从微生物和/或介质中分离PUFA。本发明特别涉及具有显着降低的总盐含量，特别是特别降低的NaCl含量的新型优化的介质。通过使用不同盐的新型组合作为其中离子的总重量比不超过1.75g / L的介质组合物，可以显着改善和显着地简化PUFA的生产。此外，所述介质优选根本不含有添加的钠盐和氯化物盐，这有助于防止由含有盐的废水引起的环境损害。

8. 发明申请

US20130331565A1 Process for Producing Acesulfame Potassium 有权
标题翻译：生产醋磺酰钾的方法
公开(公告)号：US20130331565A1
公开(公告)日：2013-12-12
申请号：US13901735
申请日：2013-05-24
申请人： Nutrinova Nutrition Specialties & Food Ingredients
发明人： Michael J. Bayer , Stephan Brietzke , Peter Groer , Christoph Mollenkopf
IPC分类号： A23L1/236 , C07C307/02
CPC分类号： A23L1/236 , A23L27/30 , C07C307/02 , C07D291/06
摘要： In one embodiment, the invention relates to processes for producing acesulfame potassium. In one embodiment, the process comprises the step of reacting a first reaction mixture to form an amidosulfamic acid salt such as a trialkyl ammonium amidosulfamic acid salt. The first reaction mixture comprises sulfamic acid, an amine, and smaller amounts, if any, acetic acid, e.g., less than 1 wt % (10000 wppm). In terms of ranges, the first reaction mixture may comprise from 1 wppm to 1 wt % acetic acid. The process further comprises the step of reacting the amidosulfamic acid salt with diketene to form an acetoacetamide salt. In preferred embodiments, the amidosulfamic acid salt formation reaction is conducted at pH levels from 5.5 to 7.0. The process further comprises the step of deriving the acesulfame-K from the acetoacetamide salt.
摘要翻译：在一个实施方案中，本发明涉及生产乙酰磺胺酸钾的方法。在一个实施方案中，该方法包括使第一反应混合物反应形成氨基磺酰胺酸盐如氨基磺酰胺酸三烷基铵盐的步骤。第一反应混合物包含氨基磺酸，胺和少量（如果有的话）乙酸，例如小于1重量％（10000wppm））。就范围而言，第一反应混合物可以包含1wppm至1wt％的乙酸。该方法还包括使氨基磺酰胺酸盐与双烯酮反应形成乙酰乙酰胺盐的步骤。在优选的实施方案中，氨基磺酰胺酸盐形成反应在5.5至7.0的pH水平下进行。该方法还包括从乙酰乙酰胺盐衍生乙酰磺胺酸K的步骤。

9. 发明申请

US20030219869A1 Expression of recombinant human proteins in Tetrahymena 有权
标题翻译：重组人蛋白在四膜虫中的表达
公开(公告)号：US20030219869A1
公开(公告)日：2003-11-27
申请号：US10395433
申请日：2003-03-24
申请人： NUTRINOVA Nutrition Specialties & Food Ingredients GmbH
发明人： Thomas Kiy , Matthias Rusing
IPC分类号： C12P021/02 , C12N001/10 , C12N015/74
CPC分类号： C07K14/765 , C12N15/79
摘要： The present invention concerns a method for production of recombinant human proteins, in which Tetrahymena cells are transformed with recombinant DNA containing at least one functional gene that codes for a human protein, the recombinant Tetrahymena cells are cultured, in which the gene that codes for a human protein is expressed and the proteins are then isolated. The present invention also concerns a corresponding method, in which the gene that codes for a human protein contains a human leader sequence that leads to secretion of the expressed protein.
摘要翻译：本发明涉及重组人蛋白质的制备方法，其中用包含编码人蛋白质的至少一个功能基因的重组DNA转化四膜虫细胞，培养重组四膜虫细胞，其中编码表达人蛋白质，然后分离蛋白质。本发明还涉及一种相应的方法，其中编码人蛋白质的基因含有导致表达的蛋白质分泌的人前导序列。

10. 发明申请

US20010016220A1 Encapsulated multifunctional biologically active food component, process for its production and its use 失效
标题翻译：封装的多功能生物活性食品成分，其生产和使用过程
公开(公告)号：US20010016220A1
公开(公告)日：2001-08-23
申请号：US09747850
申请日：2000-12-21
申请人： Nutrinova Nutrition Specialties & Food Ingredients GmbH
发明人： Martin Jager , Bernd Haber , Benno Kunz , Stephanie Strater , Jenny Weissbrodt , Hartmut Bollinger , Hans-Georg Brendle , Georg Bache
IPC分类号： A23L001/00
CPC分类号： A23L33/22 , A23L29/065 , A23L33/21 , A23P10/30 , Y02P60/877 , Y10S426/807
摘要： The invention relates to a multifunctional encapsulated biologically active food component consisting of a core which comprises at least one dietary fiber, which core is surrounded by at least one biologically active substance, in which the core and the biologically active substance(s) is (are) surrounded by one or more shell-forming substance(s).
摘要翻译：本发明涉及由核心组成的多功能包封的生物活性食品成分，其包含至少一种膳食纤维，该核心被至少一种生物活性物质包围，其中核心和生物活性物质是）被一种或多种成壳物质包围。

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