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1. 发明授权

US06773413B2 Extracorporeal blood processing methods and apparatus 有权
标题翻译：体外血液处理方法和装置
公开(公告)号：US06773413B2
公开(公告)日：2004-08-10
申请号：US09729578
申请日：2000-12-04
申请人： Muriel Keller , Marlene Bainbridge
发明人： Muriel Keller , Marlene Bainbridge
IPC分类号： A61M3700
CPC分类号： A61M1/3693 , A61M1/30 , A61M1/303 , A61M1/308 , A61M1/3692 , A61M1/3696
摘要： An extracorporeal blood processing method includes a set-up phase establishing certain conditions in blood being processed prior to separation of the blood into components. Also, a blood processing method contemporaneously extracts selected multiple blood components from a blood processing vessel. Blood is separated into components in the blood processing vessel in a centrifugal field. Further, an extracorporeal blood processing method establishes a packing factor in the blood processing vessel prior to collecting red blood cells.
摘要翻译：体外血液处理方法包括在将血液分离成组分之前在血液中建立某些条件的建立阶段。此外，血液处理方法同时从血液处理容器中提取选择的多种血液成分。血液在离心场中分离成血液处理容器中的成分。此外，体外血液处理方法在收集红细胞之前在血液处理容器中建立包装因子。

2. 发明授权

US07354415B2 Extra-corporeal blood processing method and apparatus based on donor characteristics 有权
标题翻译：基于供体特征的体外血液处理方法和装置
公开(公告)号：US07354415B2
公开(公告)日：2008-04-08
申请号：US10709196
申请日：2004-04-20
申请人： Marlene Bainbridge , Muriel Keller , Timothy M. Gordon , Michael J. McAteer , Scott D. Butzke
发明人： Marlene Bainbridge , Muriel Keller , Timothy M. Gordon , Michael J. McAteer , Scott D. Butzke
IPC分类号： A31M37/00 , C02F1/44
CPC分类号： A61M1/3693 , A61M1/30 , A61M1/303 , A61M1/308 , A61M1/3692 , A61M1/3696 , G06F19/00
摘要： Methods and apparatus particularly involving the separation of blood into blood components and the collection of such components are disclosed. In one aspect, an extra-corporeal method for the collection of plasma and red blood cells is provided, wherein the collection of plasma and red blood cells may occur simultaneously or subsequently utilizing the same dual stage blood processing vessel. The flow of blood to the blood processing vessel and return of uncollected blood components may be provided via a single needle, wherein blood is removed from and returned to a donor/patient during alternating blood removal and blood return submodes. Platelet separation and collection options are also described. In either case, prior to red blood cell collection, a set-up phase may be carried out to set a predetermined hematocrit and AC ratio. Replacement fluid delivery may optionally also be provided either substantially continuously during any collection phase(s) and/or in a bolus mode.
摘要翻译：公开了特别涉及将血液分离成血液成分并收集这些组分的方法和装置。一方面，提供了用于收集血浆和红细胞的额外体外方法，其中血浆和红细胞的收集可以同时发生或随后使用相同的双级血液处理容器。可以经由单个针提供血液加工血液到血液处理容器的流动和未收集的血液成分的返回，其中在交替的血液清除和血液返回子模式期间从血液中取出血液并返回给供体/患者。还描述了血小板分离和收集选项。在任一种情况下，在红细胞收集之前，可以进行设置阶段以设定预定的血细胞比容和AC比。替代流体输送可以任选地在任何收集阶段和/或以推注模式中基本连续地提供。

3. 发明授权

US06945948B2 Extra-corporeal dual stage blood processing method and apparatus 有权
标题翻译：超身体双期血液处理方法和装置
公开(公告)号：US06945948B2
公开(公告)日：2005-09-20
申请号：US10709194
申请日：2004-04-20
申请人： Marlene Bainbridge , Muriel Keller , Timothy M. Gordon , Michael J. McAteer , Scott D. Butzke
发明人： Marlene Bainbridge , Muriel Keller , Timothy M. Gordon , Michael J. McAteer , Scott D. Butzke
IPC分类号： G01N33/48 , A61M1/02 , A61M1/36 , B04B5/00 , A61M37/00
CPC分类号： A61M1/3693 , A61M1/30 , A61M1/303 , A61M1/308 , A61M1/3692 , A61M1/3696 , G06F19/00
摘要： Methods and apparatus particularly involving the separation of blood into blood components and the collection of such components are disclosed. In one aspect, an extra-corporeal method for the collection of plasma and red blood cells is provided, wherein the collection of plasma and red blood cells may occur simultaneously or subsequently utilizing the same dual stage blood processing vessel. The flow of blood to the blood processing vessel and return of uncollected blood components may be provided via a single needle, wherein blood is removed from and returned to a donor/patient during alternating blood removal and blood return submodes. Platelet separation and collection options are also described. In either case, prior to red blood cell collection, a set-up phase may be carried out to set a predetermined hematocrit and AC ratio. Replacement fluid delivery may optionally also be provided either substantially continuously during any collection phase(s) and/or in a bolus mode.
摘要翻译：公开了特别涉及将血液分离成血液成分并收集这些组分的方法和装置。一方面，提供了用于收集血浆和红细胞的额外体外方法，其中血浆和红细胞的收集可以同时发生或随后使用相同的双级血液处理容器。可以经由单个针提供血液加工血液到血液处理容器的流动和未收集的血液成分的返回，其中在交替的血液清除和血液返回子模式期间从血液中取出血液并返回给供体/患者。还描述了血小板分离和收集选项。在任一种情况下，在红细胞收集之前，可以进行设置阶段以设定预定的血细胞比容和AC比。替代流体输送可以任选地在任何收集阶段和/或以推注模式中基本连续地提供。

4. 发明授权

US06730055B2 Extracorporeal blood processing methods and apparatus 有权
标题翻译：体外血液处理方法和装置
公开(公告)号：US06730055B2
公开(公告)日：2004-05-04
申请号：US09803304
申请日：2001-03-09
申请人： Marlene Bainbridge , Muriel Keller , Timothy M. Gordon , Michael J. McAteer , Scott D. Butzke
发明人： Marlene Bainbridge , Muriel Keller , Timothy M. Gordon , Michael J. McAteer , Scott D. Butzke
IPC分类号： A61M3700
CPC分类号： A61M1/3693 , A61M1/30 , A61M1/303 , A61M1/308 , A61M1/3692 , A61M1/3696 , G06F19/00
摘要： Methods and apparatus particularly involving the separation of blood into blood components and the collection of such components are disclosed. In one aspect, an extracorporeal method for the collection of plasma and red blood cells is provided, wherein the collection of plasma and red blood cells may occur simultaneously or subsequently utilizing the same dual stage blood processing vessel. The flow of blood to the blood processing vessel and return of uncollected blood components may be provided via a single needle, wherein blood is removed from and returned to a donor/patient during alternating blood removal and blood return submodes. Platelet separation and collection options are also described. In either case, prior to red blood cell collection, a set-up phase may be carried out to set a predetermined hematocrit and AC ratio. Replacement fluid delivery may optionally also be provided either substantially continuously during any collection phase(s) and/or in a bolus mode.
摘要翻译：公开了特别涉及将血液分离成血液成分并收集这些组分的方法和装置。一方面，提供了用于收集血浆和红细胞的体外方法，其中血浆和红细胞的收集可以同时发生或随后使用相同的双级血液处理容器。可以经由单个针提供血液加工血液到血液处理容器的流动和未收集的血液成分的返回，其中在交替的血液清除和血液返回子模式期间从血液中取出血液并返回给供体/患者。还描述了血小板分离和收集选项。在任一情况下，在红细胞收集之前，可以进行设置阶段以设定预定的血细胞比容和AC比。替代流体输送可以任选地在任何收集阶段和/或以推注模式中基本连续地提供。

5. 发明授权

US06200287B1 Extracorporeal blood processing methods and apparatus 失效
标题翻译：体外血液处理方法和装置
公开(公告)号：US06200287B1
公开(公告)日：2001-03-13
申请号：US08924519
申请日：1997-09-05
申请人： Muriel Keller , Marlene Bainbridge
发明人： Muriel Keller , Marlene Bainbridge
IPC分类号： A61M3700
CPC分类号： A61M1/3693 , A61M1/30 , A61M1/303 , A61M1/308 , A61M1/3692 , A61M1/3696
摘要： Improved extracorporeal blood processing methods and apparatus are disclosed. In one aspect of the invention, an extracorporeal method for the collection of platelets and red blood cells, and if desired plasma, is provided, wherein the collection of platelets and red blood cells may occur in differing time periods utilizing the same blood processing vessel. The flow of blood to the blood processing vessel and return of uncollected blood components may be provided via a single needle, wherein blood is removed and returned to a donor/patient during alternating blood removal and blood return submodes. Prior to red blood cell collection, a set-up phase may be carried out during which a predetermined hematocrit and AC ratio is established.
摘要翻译：公开了改进的体外血液处理方法和装置。在本发明的一个方面，提供了用于收集血小板和红细胞以及如果需要的血浆的体外方法，其中血小板和红细胞的收集可以在不同时间段内使用相同的血液处理容器进行。可以通过单个针提供血液加工血液到血液处理容器的流动并返回未收集的血液成分，其中在交替的血液清除和血液回流子模式期间，血液被移除并返回给供体/患者。在红细胞收集之前，可以进行建立阶段，在此期间建立预定的血细胞比容和AC比。

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