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    • 2. 发明授权
    • Purification and production methods of 1-aminocyclopropanecarboxylic acid
    • 1-氨基环丙烷羧酸的纯化和制备方法
    • US07476760B2
    • 2009-01-13
    • US11183858
    • 2005-07-19
    • Ryota HamasakiMitsuru Ohno
    • Ryota HamasakiMitsuru Ohno
    • C07C62/00
    • C07C227/42C07C227/40C07C2601/02C07C229/48
    • A method purifies 1-aminocyclopropanecarboxylic acid by subjecting a crude 1-aminocyclopropanecarboxylic acid to crystallization with a solvent mixture containing an organic acid having one to five carbon atoms and a poor solvent for 1-aminocyclopropanecarboxylic acid, which poor solvent is miscible with the organic acid. In the method, the solvent mixture may further contain water. Purification may be carried out by mixing the crude 1-aminocyclopropanecarboxylic acid with the organic acid having one to five carbon atoms, removing insoluble matter by filtration, and adding the poor solvent with or without water to the filtrate to thereby crystallize 1-aminocyclopropanecarboxylic acid.
    • 通过使粗制的1-氨基环丙烷羧酸与含有1-5个碳原子的有机酸的溶剂混合物和1-氨基环丙烷羧酸的不良溶剂进行结晶来纯化1-氨基环丙烷羧酸,该溶剂与有机酸混溶 。 在该方法中,溶剂混合物可以进一步含有水。 纯化可以通过将粗制的1-氨基环丙烷羧酸与具有1-5个碳原子的有机酸混合,通过过滤除去不溶物,并将不合适的溶剂加入或不加入水中,由此使1-氨基环丙烷羧酸结晶。