专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US5693792A .beta.-lactam and cephem compounds and processes for their production 失效
标题翻译： β-内酰胺和头孢烯化合物及其生产方法
公开(公告)号：US5693792A
公开(公告)日：1997-12-02
申请号：US515166
申请日：1995-08-15
申请人： Shigeru Torii , Hideo Tanaka , Mitio Sasaoka , Takashi Shiroi , Yutaka Kameyama
发明人： Shigeru Torii , Hideo Tanaka , Mitio Sasaoka , Takashi Shiroi , Yutaka Kameyama
IPC分类号： C07D205/09 , C07D205/095 , C07D501/00 , C07D501/04 , C07D501/14 , C07D501/18 , C07D501/20 , C07D501/22 , C07D501/57 , C07D501/60 , C07D501/02
CPC分类号： C07D205/09 , C07D205/095 , C07D501/00 , Y02P20/55
摘要： The object of the invention is to provide a .beta.-lactam compound and a 2-substituted methyl-3-cephem compound, both of which are of value as intermediates for the synthesis of cephem antibiotics. The .beta.-lactam compound of the invention may be represented by the general formula ##STR1## wherein R.sup.1 represents a protected amino group, for instance; R.sup.2 represents hydrogen, for instance; R.sup.3 represents hydrogen or a carboxy-protecting group; R.sup.4 represents an aryl group which may be substituted; R.sup.5 represents an alkenyl group which may be substituted, for instance. The 2-substituted methyl-3-cephem compound of the invention may be represented by the general formula ##STR2## wherein R.sup.1, R.sup.2 and R.sup.3 are as defined above; R.sup.6 represents an aryl group which may be substituted.
摘要翻译：本发明的目的是提供β-内酰胺化合物和2-取代的甲基-3-头孢烯化合物，它们都作为合成头孢类抗生素的中间体。本发明的β-内酰胺化合物可以由通式为“IMAGE”表示，其中R 1表示被保护的氨基; R2表示氢，例如 R3表示氢或羧基保护基; R4代表可被取代的芳基; R5表示例如可被取代的烯基。本发明的2-取代的甲基-3-头孢烯化合物可以由通式（IMAGE）表示，其中R 1，R 2和R 3如上定义; R6表示可以被取代的芳基。

2. 发明授权

US5599925A Penam derivatives 失效
标题翻译： Penam衍生物
公开(公告)号：US5599925A
公开(公告)日：1997-02-04
申请号：US314307
申请日：1994-09-30
申请人： Shigeru Torii , Hideo Tanaka , Masatoshi Taniguchi , Mitio Sasaoka , Takashi Shiroi , Yutaka Kameyama
发明人： Shigeru Torii , Hideo Tanaka , Masatoshi Taniguchi , Mitio Sasaoka , Takashi Shiroi , Yutaka Kameyama
IPC分类号： C07D499/00 , C07D499/86 , C07D499/87 , C07D499/897
CPC分类号： C07D499/00 , Y02P20/55
摘要： A penam derivative of the general formula ##STR1## wherein R.sup.1 means hydrogen, halogen, amino or protected amino; R.sup.2 means hydrogen, halogen, lower alkoxy, lower acyl, lower alkyl, hydroxy- or protected hydroxy-substituted lower alkyl, hydroxy or protected hydroxy, or R.sup.1 and R.sup.2 may jointly represent oxo; R.sup.3 means hydrogen or a carboxy-protecting group; R.sup.4 means hydrogen; R.sup.5 means a group of the formula --CH.sub.2 Y where Y means halogen, --N.sub.3, --ONO.sub.2, --OR.sup.6, --OCOR.sup.6, --SCSOR.sup.6, --SCSN(R.sup.6).sub.2, --SR.sup.6, --SO.sub.2 R.sup.6, --NHR.sup.6, --N(R.sup.6).sub.2 or a substituted or unsubstituted nitrogen-containing heterocyclic group having a free valence on nitrogen; R.sup.6 means a lower alkyl, aryl or heterocyclic group which is substituted or unsubstituted; or R.sup.4 and R.sup.5 may jointly represent .dbd.CH.sub.2 ; n means 0, 1 or 2; provided, however, that where R.sup.4 and R.sup.5 jointly represent .dbd.CH.sub.2, n is not equal to 0.
摘要翻译：其中R 1表示氢，卤素，氨基或被保护的氨基; R 2表示氢，卤素，低级烷氧基，低级酰基，低级烷基，羟基或保护的羟基取代的低级烷基，羟基或保护的羟基，或者R 1和R 2可以共同表示氧代; R3表示氢或羧基保护基; R4表示氢; R5表示式-CH2Y的基团，其中Y表示卤素，-N3，-ONO2，-OR6，-OCOR6，-SCSOR6，-SCSN（R6）2，-SR6，-SO2R6，-NHR6，-N（R6） 2或在氮上具有游离价的取代或未取代的含氮杂环基; R6表示取代或未取代的低级烷基，芳基或杂环基; 或者R4和R5可以共同表示= CH2; n表示0,1或2; 但是，如果R4和R5共同表示= CH2，则n不等于0。

3. 发明授权

US5470972A Process for preparing examethylenecephem compounds 失效
标题翻译：制备二亚甲基化合物的方法
公开(公告)号：US5470972A
公开(公告)日：1995-11-28
申请号：US129130
申请日：1993-10-14
申请人： Shigeru Torii , Hideo Tanaka , Mitio Sasaoka , Takashi Shiroi , Yutaka Kameyama
发明人： Shigeru Torii , Hideo Tanaka , Mitio Sasaoka , Takashi Shiroi , Yutaka Kameyama
IPC分类号： C07D205/09 , C07D205/095 , C07D501/00 , C07D501/04 , C07D501/14 , C07D501/18 , C07D501/20 , C07D501/22 , C07D501/57 , C07D501/60 , A61K31/545
CPC分类号： C07D205/09 , C07D205/095 , C07D501/00 , Y02P20/55
摘要： The object of the invention is to provide a .beta.-lactam compound and a 2-substituted methyl-3-cephem compound, both of which are of value as intermediates for the synthesis of cephem antibiotics.The .beta.-lactam compound of the invention may be represented by the general formula ##STR1## wherein R.sup.1 represents a protected amino group, for instance; R.sup.2 represents hydrogen for instance; R.sup.3 represents hydrogen or a carboxy-protecting group; R.sup.4 represents an aryl group which may be substituted; R.sup.5 represents an alkenyl group which may be substituted, for instance. The 2-substituted methyl-3-cephem compound of the invention may be represented by the general formula ##STR2## wherein R.sup.1, R.sup.2 and R.sup.3 are as defined above; R.sup.6 represents an aryl group which may be substituted.
摘要翻译：本发明的目的是提供β-内酰胺化合物和2-取代的甲基-3-头孢烯化合物，它们都作为合成头孢类抗生素的中间体。本发明的β-内酰胺化合物可以由通式为“IMAGE”表示，其中R 1表示被保护的氨基; R2代表氢; R3表示氢或羧基保护基; R4代表可被取代的芳基; R5表示例如可被取代的烯基。本发明的2-取代的甲基-3-头孢烯化合物可以由通式（IMAGE）表示，其中R 1，R 2和R 3如上定义; R6表示可以被取代的芳基。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式