专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20090264427A1 3-Cyanoquinolines, Methods for Preparation and Use as Insulin-like Growth Factor Inhibitors 审中-公开
标题翻译： 3-氰基喹啉，制备和用作胰岛素样生长因子抑制剂的方法
公开(公告)号：US20090264427A1
公开(公告)日：2009-10-22
申请号：US12423096
申请日：2009-04-14
申请人： Scott Christian Mayer , Lori Michelle Miller
发明人： Scott Christian Mayer , Lori Michelle Miller
IPC分类号： A61K31/4709 , C07D401/12 , C07D413/14 , C07D401/14 , A61K31/5377 , A61K31/496 , A61P29/00 , A61P35/00
CPC分类号： C07D401/12 , C07D401/14 , C07D405/14
摘要： Imidazole-substituted 4-anilino-3-cyanoquinolines are described, which selectively inhibit IFGR kinase activity and are useful for treating disorders associated with IGFR kinases.
摘要翻译：描述了咪唑取代的4-苯胺基-3-氰基喹啉，其选择性地抑制IFGR激酶活性并且可用于治疗与IGFR激酶相关的疾病。

2. 发明授权

US08026307B2 Two component curable compositions 有权
标题翻译：两组分可固化组合物
公开(公告)号：US08026307B2
公开(公告)日：2011-09-27
申请号：US10577880
申请日：2004-11-03
申请人： Michelle Miller
发明人： Michelle Miller
IPC分类号： C08K3/18 , C08K3/34
CPC分类号： C08K3/346 , B82Y30/00 , C08K2201/011 , C08L63/00
摘要： A two component reactive composition is described. Each component, before they are mixed together, contains a filler having thin platelet structure, e.g. a nanoclay, and a further filler that interacts with the platelets. The individual components can have a filler loading that makes them flowable and therefore the components can readily be mixed together for ready dispensing. When the components are mixed thoroughly together, the resulting resin may have a viscosity higher than that of the individual components. The loading of the filler is preferably chosen so that the resulting blended resin is capable of being applied on to a vertical surface without experiencing significant slump. The viscosity of the mixed material can be up to 5 to 10 times or more than that of the individual components before mixing. The composition can be used in adhesives, modelling pastes, coatings, sealants, putties, mastics, stopping compounds, caulking materials, encapsulants and surface coatings, e.g. paints.
摘要翻译：描述了双组分反应性组合物。每个组分在它们混合在一起之前含有具有薄片状结构的填料，例如纳米粘土和与血小板相互作用的另外的填料。各个组件可以具有使其可流动的填料负载，因此组分可以容易地混合在一起以便于分配。当组分充分混合在一起时，所得树脂的粘度可以高于单独组分的粘度。优选选择填充物的加载，使得所得到的混合树脂能够施加到垂直表面上而不经历显着的坍落度。在混合前，混合材料的粘度可高达各组分的5至10倍或更多。该组合物可用于粘合剂，模型糊，涂料，密封剂，油灰，胶粘剂，止挡化合物，填缝材料，密封剂和表面涂层。油漆

3. 发明申请

US20100254942A1 HEPATITIS C ANTIVIRAL COMPOSITIONS AND METHODS 审中-公开
标题翻译： HEPATITIS C抗病毒组合物和方法
公开(公告)号：US20100254942A1
公开(公告)日：2010-10-07
申请号：US12670082
申请日：2008-08-04
申请人： Gary Dinneen Ewart , Carolyn Anne Luscombe , Michelle Miller
发明人： Gary Dinneen Ewart , Carolyn Anne Luscombe , Michelle Miller
IPC分类号： A61K38/21 , A61K31/7076 , A61K31/7068 , A61K31/4418 , A61K31/415 , A61K31/045 , A61P31/14 , A61K31/505
CPC分类号： C07C279/22 , A61K31/155 , A61K31/166 , A61K31/167 , A61K31/18 , A61K31/341 , A61K31/36 , A61K31/381 , A61K31/415 , A61K31/435 , A61K31/4418 , A61K31/7056 , A61K31/7064 , A61K31/7068 , A61K31/7076 , A61K38/21 , A61K38/212 , A61K45/06 , C07C311/08 , C07D213/69 , C07D231/12 , C07D307/54 , C07D333/24 , A61K2300/00
摘要： The present invention relates to novel compositions having anti-viral activity and in particular it relates to synergistic compositions active against Hepatitis C virus (HCV). The invention also relates to methods for retarding, reducing or otherwise inhibiting HCV growth and/or functional activity.
摘要翻译：本发明涉及具有抗病毒活性的新型组合物，特别涉及对丙型肝炎病毒（HCV）有活性的协同组合物。本发明还涉及用于延缓，减少或以其它方式抑制HCV生长和/或功能活性的方法。

4. 发明申请

US20070117966A1 Alphanubeta3 integrin-binding polypeptide monobodies and their use 有权
标题翻译： Alphanubeta3整合素结合多肽单体及其用途
公开(公告)号：US20070117966A1
公开(公告)日：2007-05-24
申请号：US10473770
申请日：2002-04-04
申请人： Shohei Koide , Stephen Dewhurst , Akiko Koide , Julie Richards , Michelle Miller
发明人： Shohei Koide , Stephen Dewhurst , Akiko Koide , Julie Richards , Michelle Miller
IPC分类号： C07K16/28
CPC分类号： C07K16/00 , A61K51/088 , A61K2039/505 , C07K14/78 , C07K16/2848 , C07K2317/34
摘要： The present invention relates to a polypeptide monobody which includes a modified acid sequence and renders the polypeptide monobody able to bind selectively to αvβ3 integrin. Fusion proteins and conjugates which include the polypeptide monobody, as well as compositions containing the polypeptide monobody, fusion proteins, or conjugates are also disclosed. Uses thereof include: treating or preventing an αvβ3 integrin-mediated disease or disorder, inhibiting αvβ3 integrin activity, treating a cancerous or precancerous condition, imaging tissues using positron emission tomography or magnetic resonance imaging, assessing the metastatic characteristics of a tumor, and delivering DNA to a cell.
摘要翻译：本发明涉及一种多肽单体，其包含经修饰的酸序列，并使得多肽单体能够选择性地结合到α-角蛋白3整联蛋白。还公开了包含多肽单体的融合蛋白和缀合物，以及含有多肽单体，融合蛋白或缀合物的组合物。其用途包括：治疗或预防alphavbeta3整联蛋白介导的疾病或病症，抑制alphavbeta3整联蛋白活性，治疗癌症或癌前病症，使用正电子发射断层扫描或磁共振成像成像组织，评估肿瘤的转移特征和递送DNA 到一个单元格

5. 发明申请

US20070072981A1 Two component curable compositions 有权
标题翻译：两组分可固化组合物
公开(公告)号：US20070072981A1
公开(公告)日：2007-03-29
申请号：US10577880
申请日：2004-11-03
申请人： Michelle Miller
发明人： Michelle Miller
IPC分类号： C08K9/04
CPC分类号： C08K3/346 , B82Y30/00 , C08K2201/011 , C08L63/00
摘要： A two component reactive composition is described. Each component, before they are mixed together, contains a filler having thin platelet structure, e.g. a nanoclay, and a further filler that interacts with the platelets. The individual components can have a filler loading that makes them flowable and therefore the components can readily be mixed together for ready dispensing. When the components are mixed thoroughly together, the resulting resin may have a viscosity higher than that of the individual components. The loading of the filler is preferably chosen so that the resulting blended resin is capable of being applied on to a vertical surface without experiencing significant slump. The viscosity of the mixed material can be up to 5 to 10 times or more than that of the individual components before mixing. The composition can be used in adhesives, modelling pastes, coatings, sealants, putties, mastics, stopping compounds, caulking materials, encapsulants and surface coatings, e.g. paints.
摘要翻译：描述了双组分反应性组合物。每个组分在它们混合在一起之前含有具有薄片状结构的填料，例如纳米粘土和与血小板相互作用的另外的填料。各个组件可以具有使其可流动的填料负载，因此组分可以容易地混合在一起以便于分配。当组分充分混合在一起时，所得树脂的粘度可以高于单独组分的粘度。优选选择填充物的加载，使得所得到的混合树脂能够施加到垂直表面上而不经历显着的坍落度。在混合前，混合材料的粘度可高达各组分的5至10倍或更多。该组合物可用于粘合剂，模型糊，涂料，密封剂，油灰，胶粘剂，止挡化合物，填缝材料，密封剂和表面涂层。油漆

6. 发明授权

US10138485B2 Neutral nanotransporters 有权
公开(公告)号：US10138485B2
公开(公告)日：2018-11-27
申请号：US13120341
申请日：2009-09-22
申请人： Anastasia Khvorova , William Salomon , Joanne Kamens , Dmitry Samarsky , Tod M. Woolf , Michelle Miller , Karen G. Bulock
发明人： Anastasia Khvorova , William Salomon , Joanne Kamens , Dmitry Samarsky , Tod M. Woolf , Michelle Miller , Karen G. Bulock
IPC分类号： C12N15/113 , C12N15/11
摘要： Neutral lipid formulations for nucleic acid delivery are provided according to the invention. The neutral lipid formulations include hydrophobically modified polynucleotides and fat mixtures. Methods of using the neutral lipid formulations are also provided.

7. 发明申请

US20110237522A1 NEUTRAL NANOTRANSPORTERS 审中-公开
标题翻译：中性NANOTRANSPORTERS
公开(公告)号：US20110237522A1
公开(公告)日：2011-09-29
申请号：US13120341
申请日：2009-09-22
申请人： Anastasia Khvorova , William Salomon , Joanne Kamens , Dmitry Samarsky , Tod M. Woolf , Michelle Miller , Karen G. Bulock
发明人： Anastasia Khvorova , William Salomon , Joanne Kamens , Dmitry Samarsky , Tod M. Woolf , Michelle Miller , Karen G. Bulock
IPC分类号： A61K38/14 , A61K31/7088 , A61K31/713 , C12N5/071 , A61P43/00
CPC分类号： C12N15/1136 , C12N15/111 , C12N15/113 , C12N15/1137 , C12N2310/14 , C12N2310/315 , C12N2310/321 , C12N2310/322 , C12N2310/3231 , C12N2310/3341 , C12N2310/3515 , C12N2310/3519 , C12N2310/3521 , C12N2320/32 , C12N2320/51 , C12N2320/53
摘要： Neutral lipid formulations for nucleic acid delivery are provided according to the invention. The neutral lipid formulations include hydrophobically modified polynucleotides and fat mixtures. Methods of using the neutral lipid formulations are also provided.
摘要翻译：根据本发明提供用于核酸递送的中性脂质制剂。中性脂质制剂包括疏水改性的多核苷酸和脂肪混合物。还提供了使用中性脂质制剂的方法。

8. 发明申请

US20060277233A1 Functionality disable and re-enable for programmable calculators 有权
公开(公告)号：US20060277233A1
公开(公告)日：2006-12-07
申请号：US11142506
申请日：2005-06-01
申请人： Michelle Miller , Douglas Feltz , Gary Vonberg
发明人： Michelle Miller , Douglas Feltz , Gary Vonberg
IPC分类号： G06F13/00
CPC分类号： G06F15/02 , G06F15/16
摘要： A handheld calculator with disable/re-enable capability. The calculator includes a keypad, a display screen, and circuitry internal to the calculator. The circuitry includes a microprocessor, a storage unit for storing data and programs for execution by the microprocessor to implement calculator functions. The storage unit has stored therein a disable/re-enable program that recognizes a first predetermined calculator event and in response thereto disables one or more programs, and that recognizes a second predetermined calculator event and in response thereto re-enables the disabled program. The invention allows Apps, programs and additional information that may be embedded within the Apps and programs in a calculator or other handheld calculating device to be rendered temporarily inaccessible within a relatively short period of time, and then to be restored to the calculator, again, in a relatively short period of time.

9. 外观设计

USD429570S Picture frame 失效
公开(公告)号：USD429570S
公开(公告)日：2000-08-22
申请号：US111095
申请日：1999-09-22
申请人： Michelle Miller
设计人： Michelle Miller

10. 发明授权

US08153042B2 Two component curable compositions 有权
标题翻译：两组分可固化组合物
公开(公告)号：US08153042B2
公开(公告)日：2012-04-10
申请号：US13211617
申请日：2011-08-17
申请人： Michelle Miller
发明人： Michelle Miller
IPC分类号： B28B11/04 , C08K3/18 , C08K3/34
CPC分类号： C08K3/346 , B82Y30/00 , C08K2201/011 , C08L63/00
摘要： A two component reactive composition is described, each component, before they are mixed together, contains a filler having thin platelet structure, e.g. a nanoclay, and a further filler that interacts with the platelets. The individual components can have a filler loading that makes them flowable and therefore the components can readily be mixed together for ready dispensing. When the components are mixed thoroughly together, the resulting resin may have a viscosity higher than that of the individual components. The loading of the filler is preferably chosen so that the resulting blended resin is capable of being applied on to a vertical surface without experiencing significant slump. The viscosity of the mixed material can be up to 5 to 10 times or more than that of the individual components before mixing. The composition can be used in adhesives, modelling pastes, coatings, sealants, putties, mastics, stopping compounds, caulking materials, encapsulants and surface coatings.
摘要翻译：描述了两组分反应性组合物，每种组分在它们混合在一起之前，含有具有薄片状结构的填料，纳米粘土和与血小板相互作用的另外的填料。各个组件可以具有使其可流动的填料负载，因此组分可以容易地混合在一起以便于分配。当组分充分混合在一起时，所得树脂的粘度可以高于单独组分的粘度。优选选择填充物的加载，使得所得到的混合树脂能够施加到垂直表面上而不经历显着的坍落度。在混合前，混合材料的粘度可高达各组分的5至10倍或更多。该组合物可用于粘合剂，造型浆料，涂料，密封剂，油灰，胶泥，停止化合物，填缝材料，密封剂和表面涂层。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式