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1. 发明授权

US08852218B2 Apparatus and methods for occluding an anatomical structure 有权
标题翻译：用于闭塞解剖结构的装置和方法
公开(公告)号：US08852218B2
公开(公告)日：2014-10-07
申请号：US13010509
申请日：2011-01-20
申请人： James David Hughett, Sr. , Salvatore Privitera , Michael D. Hooven
发明人： James David Hughett, Sr. , Salvatore Privitera , Michael D. Hooven
IPC分类号： A61B17/122
CPC分类号： A61B17/12022 , A61B17/08 , A61B17/1227 , A61B17/1285 , A61B2017/1205
摘要： Apparatus and methods are disclosed for occluding an anatomical structure including an occlusion apparatus having first and second beams and at least one connector for connecting the respective ends of the beams together. The occlusion apparatus may be adapted for use in a deployment device having a pair of jaws and optionally having a respective pair of shuttle bodies for releasably connecting an occlusion apparatus to the jaws while in an open position and for releasing the occlusion device from the jaws while in a closed position. A system for occluding an anatomical structure is also disclosed that includes an occlusion apparatus and a deployment device for holding the occlusion apparatus in an open position for locating the occlusion device adjacent the anatomical structure to be occluded and then moving the occlusion apparatus to a closed position and locking the occlusion apparatus in the closed position.
摘要翻译：公开了用于闭塞解剖结构的装置和方法，所述解剖结构包括具有第一和第二梁的闭塞装置和用于将梁的相应端部连接在一起的至少一个连接器。闭塞装置可以适用于具有一对钳口的展开装置，并且可选地具有相应的一对梭体，用于在处于打开位置时将闭塞装置可释放地连接到钳口，并且用于将咬合装置从夹爪释放，同时处于关闭状态。还公开了一种用于闭塞解剖结构的系统，其包括闭塞装置和用于将闭塞装置保持在打开位置的展开装置，用于将闭塞装置邻近待闭塞的解剖结构定位，然后将闭塞装置移动到闭合位置并将闭塞装置锁定在关闭位置。

2. 发明授权

US08114075B2 Method and apparatus for ablating cardiac tissue with guide facility 有权
标题翻译：用引导装置消融心脏组织的方法和装置
公开(公告)号：US08114075B2
公开(公告)日：2012-02-14
申请号：US11841146
申请日：2007-08-20
申请人： Michael D. Hooven
发明人： Michael D. Hooven
IPC分类号： A61B18/14
CPC分类号： A61B17/00234 , A61B18/1445 , A61B18/1492 , A61B90/11 , A61B2017/00243 , A61B2017/00278 , A61B2017/2945 , A61B2018/00351 , A61B2018/00577 , A61B2018/1432 , A61M2025/09175
摘要： A method and apparatus for ablation of cardiac tissue at a selected cardiac location is achieved by providing at least one flexible elongated guide facility having a first end, a second end, and an intermediate portion extending between the first and second ends and by providing an ablation instrument which includes at least a pair of relatively moveable clamping jaws being disposed to engage and ablate the selected cardiac location. Each guide facility is adapted for introduction into a patient's chest through an opening and for advancement to the selected cardiac location such that the intermediate portion engages the selected cardiac location and the guide facility is withdrawn through the instrument receiving passage. At least one jaw of the ablation instrument engages with the guide facility and is guided to the selected cardiac location with the aid of the guide facility to ablate the selected cardiac location.
摘要翻译：通过提供至少一个具有第一端，第二端和第二端以及在第一和第二端之间延伸的中间部分的柔性细长引导装置，并且通过提供消融来实现在选定心脏位置处消融心脏组织的方法和装置所述仪器包括至少一对可相对移动的夹爪，所述夹钳设置成啮合并消融所选择的心脏位置。每个引导装置适于通过开口引入病人的胸部并且进入所选择的心脏位置，使得中间部分接合所选择的心脏位置，并且引导装置通过器械接收通道被抽出。消融器具的至少一个钳口与引导设备接合并且借助于引导设备被引导到选定的心脏位置以消融所选择的心脏位置。

3. 发明申请

US20100305562A1 Ablation Device With Cooled Electrodes And Methods of Use 有权
标题翻译：具有冷却电极的消融装置和使用方法
公开(公告)号：US20100305562A1
公开(公告)日：2010-12-02
申请号：US12767122
申请日：2010-04-26
申请人： Matthew J. Winkler , Peter F. Staats , Warren P. Williamson, IV , Jason Iain Gilthero , Michael D. Hooven , David J. Drachman
发明人： Matthew J. Winkler , Peter F. Staats , Warren P. Williamson, IV , Jason Iain Gilthero , Michael D. Hooven , David J. Drachman
IPC分类号： A61B18/14 , A61B18/18
CPC分类号： A61B18/1482 , A61B2017/00084 , A61B2018/00023 , A61B2018/1475
摘要： An electrosurgical end effector for ablating tissue is provided that comprises at least one electrically-conductive ablation member adapted to be connected to a source of RF energy, with the ablation member having a tissue engaging surface and an internal fluid passageway. Preferably, the end effector includes two electrically conductive ablation members that are electrically isolated from one another.
摘要翻译：提供了用于烧蚀组织的电外科末端执行器，其包括适于连接到RF能量源的至少一个导电消融部件，消融部件具有组织接合表面和内部流体通道。优选地，端部执行器包括彼此电隔离的两个导电消融构件。

4. 发明授权

US07543589B2 Method for ablating cardiac tissue 有权
标题翻译：消融心脏组织的方法
公开(公告)号：US07543589B2
公开(公告)日：2009-06-09
申请号：US11675195
申请日：2007-02-15
申请人： Michael D. Hooven
发明人： Michael D. Hooven
IPC分类号： A61B18/18 , A61B18/14
CPC分类号： A61B18/1445 , A61B18/14 , A61B2017/00026 , A61B2017/00243 , A61B2017/2945 , A61B2018/00023 , A61B2018/00363 , A61B2018/00642 , A61B2018/00738 , A61B2018/00755 , A61B2018/00875 , A61B2018/0212 , A61B2018/0225 , A61B2018/0262 , A61B2018/1432 , A61B2018/145
摘要： A method and apparatus for transmural ablation using an instrument containing two electrodes or cryogenic probes. A clamping force is exerted on the two electrodes or probes such that the tissue of the hollow organ is clamped therebetween. Bipolar RF energy is then applied between the two electrodes, or the probes are cryogenically cooled, thus ablating the tissue therebetween. The method provides for ablating cardiac tissue of a patient utilizing a sub-xyphoid approach and identifying cardiac tissue prior to ablation.
摘要翻译：使用包含两个电极或低温探针的仪器进行透壁消融的方法和装置。夹紧力施加在两个电极或探针上，使得中空器官的组织夹在其间。然后将双极RF能量施加在两个电极之间，或者探针被低温冷却，从而烧蚀它们之间的组织。该方法提供了消融患者的心脏组织，利用次级假体方法并在消融前识别心脏组织。

5. 发明授权

US07530980B2 Bipolar transmural ablation method and apparatus 有权
标题翻译：双极透壁消融法及装置
公开(公告)号：US07530980B2
公开(公告)日：2009-05-12
申请号：US11104725
申请日：2005-04-13
申请人： Michael D. Hooven
发明人： Michael D. Hooven
IPC分类号： A61B18/04
CPC分类号： A61B18/1492 , A61B18/1482 , A61B2018/00351 , A61B2018/00839 , A61B2018/1435
摘要： A method and apparatus for creating transmural ablations in heart tissue, for example, may include two or more electrodes adapted to be connected to opposite poles of a bipolar RF generator so as to energize the electrodes to ablate cardiac tissue between the electrodes. A first electrode may be inserted into cardiac tissue at a first location and a second electrode may be inserted into cardiac tissue at a second location which is spaced from the first location. At least one of the electrodes may be adapted to provide a sufficiently low current density in the vicinity of the electrode to avoid substantial tissue desiccation when energized. Alternatively, the apparatus may include at least one bipolar ablation electrode which comprises an elongated conductive member of spiral shape having a pitch sufficiently small to provide sufficient surface area to avoid substantial desiccation of tissue when energized by a bipolar RF generator.
摘要翻译：例如，用于在心脏组织中产生透壁性消融的方法和装置可以包括适于连接到双极RF发生器的相反极的两个或更多个电极，以激励电极以消除电极之间的心脏组织。第一电极可以在第一位置处插入心脏组织中，并且第二电极可以在与第一位置间隔开的第二位置处插入心脏组织中。电极中的至少一个可以适于在电极附近提供足够低的电流密度，以在通电时避免实质的组织干燥。或者，该装置可以包括至少一个双极消融电极，其包括具有足够小间距的螺旋形状的细长导电构件，以提供足够的表面积，以避免由双极RF发生器激励时组织的实质性干燥。

6. 发明申请

US20080065066A1 METHOD AND APPARATUS FOR ABLATING CARDIAC TISSUE WITH GUIDE FACILITY 有权
标题翻译：用指南设备排除心脏组织的方法和装置
公开(公告)号：US20080065066A1
公开(公告)日：2008-03-13
申请号：US11841146
申请日：2007-08-20
申请人： Michael D. Hooven
发明人： Michael D. Hooven
IPC分类号： A61B18/14
CPC分类号： A61B17/00234 , A61B18/1445 , A61B18/1492 , A61B90/11 , A61B2017/00243 , A61B2017/00278 , A61B2017/2945 , A61B2018/00351 , A61B2018/00577 , A61B2018/1432 , A61M2025/09175
摘要： A method and apparatus for ablation of cardiac tissue at a selected cardiac location is achieved by providing at least one flexible elongated guide facility having a first end, a second end, and an intermediate portion extending between the first and second ends and by providing an ablation instrument which includes at least a pair of relatively moveable clamping jaws being disposed to engage and ablate the selected cardiac location. Each guide facility is adapted for introduction into a patient's chest through an opening and for advancement to the selected cardiac location such that the intermediate portion engages the selected cardiac location and the guide facility is withdrawn through the instrument receiving passage. At least one jaw of the ablation instrument engages with the guide facility and is guided to the selected cardiac location with the aid of the guide facility to ablate the selected cardiac location.
摘要翻译：通过提供至少一个具有第一端，第二端和第二端以及在第一和第二端之间延伸的中间部分的柔性细长引导装置，并且通过提供消融来实现在选定心脏位置处消融心脏组织的方法和装置所述仪器包括至少一对可相对移动的夹爪，所述夹钳设置成啮合并消融所选择的心脏位置。每个引导装置适于通过开口引入病人的胸部并且进入所选择的心脏位置，使得中间部分接合所选择的心脏位置，并且引导装置通过器械接收通道被抽出。消融器具的至少一个钳口与引导设备接合并且借助于引导设备被引导到选定的心脏位置以消融所选择的心脏位置。

7. 发明授权

US07288092B2 Method and apparatus for ablating cardiac tissue with guide facility 有权
标题翻译：用引导装置消融心脏组织的方法和装置
公开(公告)号：US07288092B2
公开(公告)日：2007-10-30
申请号：US10829701
申请日：2004-04-22
申请人： Michael D. Hooven
发明人： Michael D. Hooven
IPC分类号： A61B18/14 , A61B18/18
CPC分类号： A61B17/00234 , A61B18/1445 , A61B18/1492 , A61B90/11 , A61B2017/00243 , A61B2017/00278 , A61B2017/2945 , A61B2018/00351 , A61B2018/00577 , A61B2018/1432 , A61M2025/09175
摘要： A method and apparatus for ablation of cardiac tissue at a selected cardiac location is achieved by providing at least one flexible elongated guide facility having a first end, a second end, and an intermediate portion extending between the first and second ends and by providing an ablation instrument which includes at least a pair of relatively moveable clamping jaws being disposed to engage and ablate the selected cardiac location. Each guide facility is adapted for introduction into a patient's chest through an opening and for advancement to the selected cardiac location such that the intermediate portion engages the selected cardiac location and the guide facility is withdrawn through the instrument receiving passage. At least one jaw of the ablation instrument engages with the guide facility and is guided to the selected cardiac location with the aid of the guide facility to ablate the selected cardiac location.
摘要翻译：通过提供至少一个具有第一端，第二端和第二端以及在第一和第二端之间延伸的中间部分的柔性细长引导装置，并且通过提供消融来实现在选定心脏位置处消融心脏组织的方法和装置所述仪器包括至少一对可相对移动的夹爪，所述夹钳设置成啮合并消融所选择的心脏位置。每个引导装置适于通过开口引入病人的胸部并且进入所选择的心脏位置，使得中间部分接合所选择的心脏位置，并且引导装置通过器械接收通道被抽出。消融器具的至少一个钳口与引导设备接合并且借助于引导设备被引导到选定的心脏位置以消融所选择的心脏位置。

8. 发明申请

US20070185477A1 Removable Cryogenic Probe Appliance 审中-公开
标题翻译：可移动低温探针设备
公开(公告)号：US20070185477A1
公开(公告)日：2007-08-09
申请号：US11672328
申请日：2007-02-07
申请人： Michael D. Hooven
发明人： Michael D. Hooven
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B2017/00243 , A61B2017/0046 , A61B2018/00095 , A61B2018/0262
摘要： A removable cryogenic probe appliance is disclosed comprising a proximal portion and a distal portion, the proximal portion being releasably attachable to a cryogenic probe. The appliance further comprises a material having high thermal conductivity for conducting heat between said proximal and distal portions. A cryogenic probe system and methods of forming and using a cryogenic probe of selected shape are also disclosed, comprising providing a plurality of removable cryogenic probe appliances of differing shapes, selecting one of said appliances of the desired shape, and attaching the proximal portion of such selected appliance to a cryogenic probe.
摘要翻译：公开了一种可移除的低温探针装置，其包括近端部分和远端部分，近端部分可释放地附接到低温探针。该器具还包括具有高热导率的材料，用于在所述近端部分和远端部分之间传导热量。还公开了低温探针系统以及形成和使用所选形状的低温探针的方法，包括提供多种具有不同形状的可移除的低温探针器具，选择所需形状的所述器具之一，以及将其中的近端部分选择的设备到低温探针。

9. 发明授权

US06905498B2 Transmural ablation device with EKG sensor and pacing electrode 有权
标题翻译：具有EKG传感器和起搏电极的透壁消融装置
公开(公告)号：US06905498B2
公开(公告)日：2005-06-14
申请号：US10158985
申请日：2002-05-31
申请人： Michael D. Hooven
发明人： Michael D. Hooven
IPC分类号： A61B17/00 , A61B18/14 , A61B18/18
CPC分类号： A61B18/1445 , A61B2017/00026 , A61B2017/00243 , A61B2017/2945 , A61B2018/00363 , A61B2018/00642 , A61B2018/00755 , A61B2018/00875 , A61B2018/1432 , A61B2018/145
摘要： An apparatus for transmural ablation using an instrument containing two electrodes. The electrodes extend along the surfaces of mating jaw members which are moveable between open and clamped positions. The electrodes are connected to an RF energy source so that, when activated, they are of opposite polarity. An EKG sensor is located on one of the jaw members and spaced from the electrode so that, when the electrodes are activated to form a line of ablation, the EKG sensor contacts the tissue outside the line of ablation. A pacing electrode is located on one of the jaw members so as to be on the opposite side of the line of ablation from the EKG sensor. Thus, if the line of ablation is not transmural, the EKG sensor will be able to detect signals generated by the pacing electrode.
摘要翻译：一种使用包含两个电极的仪器进行透壁消融的装置。电极沿着可在打开位置和夹紧位置之间移动的配合钳口构件的表面延伸。电极连接到RF能量源，使得当被激活时，它们具有相反的极性。 EKG传感器位于一个钳口构件上并与电极间隔开，使得当电极被激活以形成消融线时，EKG传感器接触消融线以外的组织。起搏电极位于一个钳口构件上，以便与EKG传感器在消融线的相反侧。因此，如果消融线不是透壁的，则EKG传感器将能够检测由起搏电极产生的信号。

10. 发明授权

US06896673B2 Method for transmural ablation 有权
标题翻译：透壁消融方法
公开(公告)号：US06896673B2
公开(公告)日：2005-05-24
申请号：US10327831
申请日：2002-12-23
申请人： Michael D. Hooven
发明人： Michael D. Hooven
IPC分类号： A61B18/12 , A61B17/00 , A61B18/14 , A61B18/18
CPC分类号： A61B18/1445 , A61B5/01 , A61B5/053 , A61B2017/00026 , A61B2017/00243 , A61B2017/2945 , A61B2018/00363 , A61B2018/00642 , A61B2018/00755 , A61B2018/00875 , A61B2018/1432 , A61B2018/145
摘要： A method for transmural ablation using an instrument containing two electrodes or cryogenic probes. A clamping force is exerted on the two electrodes or probes such that the tissue of the hollow organ is clamped therebetween. Bipolar RF energy is then applied between the two electrodes, or the probes are cryogenically cooled, thus ablating the tissue therebetween. A monitoring device measures a suitable parameter, such as impedance or temperature, and indicates when the tissue between the electrodes has been fully ablated.
摘要翻译：一种使用包含两个电极或低温探针的仪器进行透壁消融的方法。夹紧力施加在两个电极或探针上，使得中空器官的组织夹在其间。然后将双极RF能量施加在两个电极之间，或者探针被低温冷却，从而烧蚀它们之间的组织。监测装置测量合适的参数，例如阻抗或温度，并指示电极之间的组织何时完全消融。

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