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1. 发明授权

US08394960B2 Thiazole carboxamide derivatives and their use to treat cancer 有权
标题翻译：噻唑甲酰胺衍生物及其用于治疗癌症的用途
公开(公告)号：US08394960B2
公开(公告)日：2013-03-12
申请号：US12738532
申请日：2008-10-27
申请人： Gerald W. Shipps, Jr. , Matthew Richards , Cliff C. Cheng , Xiaohua Huang
发明人： Gerald W. Shipps, Jr. , Matthew Richards , Cliff C. Cheng , Xiaohua Huang
IPC分类号： C07D401/00 , A61K31/445
CPC分类号： C07D417/14
摘要： The present invention relates to novel Heterocyclic Ether or Thioether Derivatives, compositions comprising the Heterocyclic Ether or Thioether Derivatives, and methods for using the Heterocyclic Ether or Thioether Derivatives for treating or preventing a proliferative disorder, an anti-proliferative disorder, inflammation, arthritis, a central nervous system disorder, a cardiovascular disease, alopecia, a neuronal disease, an ischemic injury, a viral infection, a fungal infection, or a disorder related to the activity of a protein kinase.
摘要翻译：本发明涉及新颖的杂环醚或硫醚衍生物，包含杂环醚或硫代醚衍生物的组合物，以及使用杂环醚或硫代醚衍生物治疗或预防增殖性病症，抗增殖病症，炎症，关节炎，中枢神经系统疾病，心血管疾病，脱发，神经元疾病，缺血性损伤，病毒感染，真菌感染或与蛋白激酶的活性相关的病症。

2. 发明授权

US08591943B2 Pyrazolo[1,5-a]pyrimidine derivatives as mTOR inhibitors 有权
标题翻译：吡唑并[1,5-a]嘧啶衍生物，为mTOR抑制剂
公开(公告)号：US08591943B2
公开(公告)日：2013-11-26
申请号：US13263193
申请日：2010-04-08
申请人： Yongqi Deng , Binyuan Sun , Hongbo Zeng , Matthew Richards , Gerald W. Shipps, Jr. , Cliff C. Cheng , Yinyan Zhao , Andrew McRiner , Zhaoyang Meng , Yang Nan , Mehul F. Patel , Iwona E. Wrona , Panduranga Adulla Reddy , Brian M. Eklov , Shuyi Tang , Duan Liu , Amit K. Mandal , Lianyun Zhao , M. Arshad Siddiqui
发明人： Yongqi Deng , Binyuan Sun , Hongbo Zeng , Matthew Richards , Gerald W. Shipps, Jr. , Cliff C. Cheng , Yinyan Zhao , Andrew McRiner , Zhaoyang Meng , Yang Nan , Mehul F. Patel , Iwona E. Wrona , Panduranga Adulla Reddy , Brian M. Eklov , Shuyi Tang , Duan Liu , Amit K. Mandal , Lianyun Zhao , M. Arshad Siddiqui
IPC分类号： A61K9/127 , A61K39/395 , A61K31/554 , A61K31/541 , A61K31/5377 , A61K38/50 , A61K31/553 , A61K33/24 , A61K31/704 , A61K31/551 , A61K31/538 , A61K31/519
CPC分类号： C07D487/04 , C07D519/00
摘要： The present invention provides methods for inhibiting mTOR using pyrazolo[1,5-a]pyrimidine compounds and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with mTOR using such compounds.
摘要翻译：本发明提供使用吡唑并[1,5-a]嘧啶化合物抑制mTOR的方法以及使用这些化合物治疗，预防，抑制或改善与mTOR相关的一种或多种疾病的方法。

3. 发明申请

US20130052076A1 SEPARATION METHOD 审中-公开
标题翻译：分离方法
公开(公告)号：US20130052076A1
公开(公告)日：2013-02-28
申请号：US13695993
申请日：2011-05-04
申请人： Andrew Chryss , Andreas Monch , Jasbir Khosa , Matthew Richards , David Freeman
发明人： Andrew Chryss , Andreas Monch , Jasbir Khosa , Matthew Richards , David Freeman
IPC分类号： C22B34/12 , C22C27/00 , C22C14/00 , C22C16/00 , C22B34/14 , F27B17/00
CPC分类号： B01D1/24 , B01D2251/402 , C22B9/02 , C22B9/04 , C22B34/00 , C22B34/10 , C22B34/12 , C22B34/1263 , C22B34/1268 , C22B34/1272 , C22B34/129 , C22B34/1295 , C22B34/14 , Y02P10/234
摘要： A process for recovering metal from a process material comprising the metal and a component that is more volatile than the metal, which process comprises: transporting the process material in a retort provided in a furnace, the retort being operated under vacuum and at a temperature sufficient to cause sublimation of the component from the process material thereby producing purified metal; depositing the component that has been sublimed on a cool surface; removing purified metal from the retort; and removing deposited component from the cool surface.
摘要翻译：一种从包含金属和比金属更易挥发的组分的工艺材料中回收金属的方法，该方法包括：将处理材料输送到设置在炉中的蒸馏器中，蒸煮器在真空下并在足够的温度下操作以使该组分从该加工材料升华从而产生纯化的金属; 将已经升华的组分沉积在凉爽的表面上; 从蒸馏器中除去纯化的金属; 并从冷表面去除沉积的组分。

4. 发明申请

US20100130465A1 2-AMINOTHIAZOLE-4-CARBOXYLIC AMIDES AS PROTEIN KINASE INHIBITORS 有权
标题翻译：作为蛋白激酶抑制剂的2-氨基噻唑-4-羧酰胺
公开(公告)号：US20100130465A1
公开(公告)日：2010-05-27
申请号：US12447710
申请日：2007-10-29
申请人： Gerald W. Shipps, JR. , Cliff C. Cheng , Xiaohua Huang , Thierry O. Fischmann , Jose S. Duca , Matthew Richards , Hongbo Zeng , Binyuan Sun , Panduranga A. Reddy , Lianyun Zhao , Shuyi Tang , Tzu T. Wong , Praveen K. Tadikonda , Luis E. Torres , M. Arshad Siddiqui , Michael P. Dwyer , Kartik M. Keertikar , Timothy J. Guzi
发明人： Gerald W. Shipps, JR. , Cliff C. Cheng , Xiaohua Huang , Thierry O. Fischmann , Jose S. Duca , Matthew Richards , Hongbo Zeng , Binyuan Sun , Panduranga A. Reddy , Lianyun Zhao , Shuyi Tang , Tzu T. Wong , Praveen K. Tadikonda , Luis E. Torres , M. Arshad Siddiqui , Michael P. Dwyer , Kartik M. Keertikar , Timothy J. Guzi
IPC分类号： A61K31/438 , C07D417/14 , A61K31/497 , C07D471/10 , C07D413/14 , A61K31/5377 , A61K31/551
CPC分类号： C07D277/56 , A61K31/435 , A61K31/439 , A61K31/4439 , A61K31/454 , A61K31/4545 , A61K31/496 , A61K31/5377 , A61K31/551 , A61K45/06 , C07D417/04 , C07D417/12 , C07D417/14 , C07D471/04 , C07D471/10 , C07D487/04 , C07D513/04 , A61K2300/00
摘要： The present invention relates to novel Anilinopiperazine Derivatives of formula (I), compositions comprising the Anilinopiperazine Derivatives, and methods for using the Anilinopiperazine Derivatives for treating or preventing a proliferative disorder, an anti-proliferative disorder, inflammation, arthritis, a central nervous system disorder, a cardiovascular disease, alopecia, a neuronal disease, an ischemic injury, a viral disease, a fungal infection, or a disorder related to the activity of a protein kinase.
摘要翻译：本发明涉及式（I）的新型苯胺基哌嗪衍生物，包含苯胺基哌嗪衍生物的组合物，以及使用苯胺基哌嗪衍生物治疗或预防增殖性病症，抗增殖病症，炎症，关节炎，中枢神经系统疾病，心血管疾病，脱发，神经元疾病，缺血性损伤，病毒性疾病，真菌感染或与蛋白激酶活性相关的病症。

5. 发明申请

US20100055090A1 2-AMINOTHIAZOLE-4-CARBOXYLIC AMIDES AS PROTEIN KINASE INHIBITORS 有权
公开(公告)号：US20100055090A1
公开(公告)日：2010-03-04
申请号：US12447709
申请日：2007-10-29
申请人： Gerald W. Shipps, JR. , Cliff C. Cheng , Xiaohua Huang , Thierry O. Fischmann , Jose S. Duca , Matthew Richards
发明人： Gerald W. Shipps, JR. , Cliff C. Cheng , Xiaohua Huang , Thierry O. Fischmann , Jose S. Duca , Matthew Richards
IPC分类号： A61K31/496 , C07D417/12 , C07D417/14 , A61K31/454 , A61K31/506 , A61K33/24 , A61K39/395 , A61P35/00
CPC分类号： C07D277/56 , C07D417/12 , C07D417/14 , C07D471/04
摘要： The present invention relates to novel Anilinopiperazine Derivatives of formula (I), compositions comprising the Anilinopiperazine Derivatives, and methods for using the Anilinopiperazine Derivatives for treating or preventing a proliferative disorder, an anti-proliferative disorder, inflammation, arthritis, a central nervous system disorder, a cardiovascular disease, alopecia, a neuronal disease, an ischemic injury, a viral disease, a fungal infection, or a disorder related to the activity of a protein kinase.

6. 发明申请

US20090049342A1 Apparatus, System, and Method for Adjusting Trace Data Granularity 审中-公开
标题翻译：用于调整跟踪数据粒度的装置，系统和方法
公开(公告)号：US20090049342A1
公开(公告)日：2009-02-19
申请号：US12259084
申请日：2008-10-27
申请人： Gary I. Dickenson , Thomas Charles Jarvis , Paul Matthew Richards
发明人： Gary I. Dickenson , Thomas Charles Jarvis , Paul Matthew Richards
IPC分类号： G06F11/34
CPC分类号： G06F11/3636
摘要： A method is disclosed for adjusting trace data granularity. An initialization module sets a base granularity for trace data recorded for a component. A registration module registers a condition counter comprising a condition set. The threshold module sets a count threshold for the condition counter. An increment module counts each instance of the condition set. An adjustment module adjusts the granularity of trace data stored for the component to a modified granularity if the condition count exceeds the count threshold. In one embodiment, a timer module times an adjusted trace data granularity time interval. The adjustment module may set the granularity of the trace data to the base granularity when the adjusted trace data granularity time interval exceeds a specified time interval.
摘要翻译：公开了一种用于调整跟踪数据粒度的方法。初始化模块为记录的组件的跟踪数据设置基本粒度。注册模块注册包括条件集的条件计数器。阈值模块设置条件计数器的计数阈值。增量模块对条件集的每个实例进行计数。如果条件数超过计数阈值，则调整模块将存储在组件中的跟踪数据的粒度调整为修改的粒度。在一个实施例中，定时器模块对经调整的跟踪数据粒度时间间隔进行乘法。当调整的跟踪数据粒度时间间隔超过指定的时间间隔时，调整模块可以将跟踪数据的粒度设置为基本粒度。

7. 发明申请

US20110044940A1 Thiazole Carboxamide Derivatives and Their Use to Treat Cancer 有权
标题翻译：噻唑羧酰胺衍生物及其用于治疗癌症
公开(公告)号：US20110044940A1
公开(公告)日：2011-02-24
申请号：US12738532
申请日：2008-10-27
申请人： Gerald W. Shipps, JR. , Matthew Richards , Cliff C. Cheng , Xiaohua Huang
发明人： Gerald W. Shipps, JR. , Matthew Richards , Cliff C. Cheng , Xiaohua Huang
IPC分类号： A61K31/454 , C07D417/14 , C07D417/12 , A61K31/4545 , A61K39/395 , A61K38/20 , A61K38/21 , A61K33/24 , A61K31/704 , A61K31/7048 , A61K31/4375 , A61K31/513 , A61K31/519 , A61K31/675 , A61K31/7068 , A61K31/568 , A61K38/50 , A61K31/573 , A61K38/14 , A61K31/496 , A61P35/00 , A61K31/5377 , A61K31/52 , A61K31/473
CPC分类号： C07D417/14
摘要： The present invention relates to novel Heterocyclic Ether or Thioether Derivatives, compositions comprising the Heterocyclic Ether or Thioether Derivatives, and methods for using the Heterocyclic Ether or Thioether Derivatives for treating or preventing a proliferative disorder, an anti-proliferative disorder, inflammation, arthritis, a central nervous system disorder, a cardiovascular disease, alopecia, a neuronal disease, an ischemic injury, a viral infection, a fungal infection, or a disorder related to the activity of a protein kinase.
摘要翻译：本发明涉及新颖的杂环醚或硫醚衍生物，包含杂环醚或硫代醚衍生物的组合物，以及使用杂环醚或硫代醚衍生物治疗或预防增殖性病症，抗增殖性疾病，炎症，关节炎，中枢神经系统疾病，心血管疾病，脱发，神经元疾病，缺血性损伤，病毒感染，真菌感染或与蛋白激酶活性相关的病症。

8. 发明授权

US07634649B2 Device initiated mode switching 有权
标题翻译：设备启动模式切换
公开(公告)号：US07634649B2
公开(公告)日：2009-12-15
申请号：US11927447
申请日：2007-10-29
申请人： Stephen LaRoux Blinick , Paul Matthew Richards
发明人： Stephen LaRoux Blinick , Paul Matthew Richards
IPC分类号： G06F9/00 , G06F9/24 , G06F15/177
CPC分类号： G06F11/2289
摘要： Provided are a method, system, deployment and article of manufacture, wherein in one embodiment, a mode of operation may be switched to a service mode by detecting a device inserted into a connector of an input/output port of a system. In the illustrated embodiment, the device has a connector and a wire which loops a code received from the input/output port back to the input/output port. Upon detecting receipt of the transmitted code, the mode of operation may be switched to a service mode. Other embodiments are described and claimed.
摘要翻译：提供了一种方法，系统，部署和制品，其中在一个实施例中，可以通过检测插入到系统的输入/输出端口的连接器中的设备来将操作模式切换到服务模式。在所示实施例中，设备具有连接器和将从输入/输出端口接收的代码循环回输入/输出端口的线。在检测到发送的代码的接收时，可以将操作模式切换到服务模式。描述和要求保护其他实施例。

9. 发明授权

US07624336B2 Selection of status data from synchronous redundant devices 失效
标题翻译：从同步冗余设备选择状态数据
公开(公告)号：US07624336B2
公开(公告)日：2009-11-24
申请号：US10984071
申请日：2004-11-08
申请人： Timothy James Crawford , James Mathew Davison , Daniel Fernando de Araujo , Paul Matthew Richards
发明人： Timothy James Crawford , James Mathew Davison , Daniel Fernando de Araujo , Paul Matthew Richards
IPC分类号： G06F11/00
CPC分类号： G06F11/2015
摘要： Techniques are provided for selecting status data. Redundant views are obtained from multiple synchronous redundant devices. It is determined that the redundant views from the multiple synchronous redundant devices are conflicting. A redundant view score is calculated for each of the redundant views based on one or more characteristics from each of at least two characteristic types, wherein the characteristics are associated with weighted scores. One of the redundant views is selected based on the calculated redundant view score for each of the redundant views.
摘要翻译：提供技术来选择状态数据。从多个同步冗余设备获得冗余视图。确定来自多个同步冗余设备的冗余视图是冲突的。基于来自至少两种特征类型中的每一种的一个或多个特征，为每个冗余视图计算冗余视图分数，其中所述特征与加权分数相关联。基于每个冗余视图的计算冗余视图分数来选择其中一个冗余视图。

10. 发明授权

US07618482B2 Oil tank for dry sump engines 有权
标题翻译：油箱用于干式油底壳发动机
公开(公告)号：US07618482B2
公开(公告)日：2009-11-17
申请号：US11281309
申请日：2005-11-17
申请人： Matthew Richards
发明人： Matthew Richards
IPC分类号： B01D19/00
CPC分类号： F16N39/002 , F01M11/00 , F01M2013/0427
摘要： An oil tank for a dry sump engine has a housing having an upper region and a lower region in which the oil is contained. The lower region has an oil outlet to feed a pump which supplies oil to the engine. The upper region houses a swirl tube connected to an oil inlet for air to separate from the incoming oil. The upper region includes an air outlet and is provided with two dished baffle plates each shaped to form a collector area which slopes towards the swirl tube in order to reduce droplets of condensation formed in the upper region flowing into the lower region. The wall of the swirl tube is heated by the incoming oil to promote vaporization of droplets of condensation collected in the collector area.
摘要翻译：用于干式集油器发动机的油箱具有壳体，该壳体具有容纳油的上部区域和下部区域。下部区域具有出油口以供给向发动机供油的泵。上部区域容纳与油入口连接的旋流管，用于空气与进入的油分离。上部区域包括空气出口，并且设置有两个碟形挡板，每个挡板形成为形成朝向旋转管倾斜的收集器区域，以便减少在流入下部区域的上部区域中形成的冷凝液滴。旋流管的壁被进入的油加热以促进收集在收集器区域中的冷凝液滴的蒸发。

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