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1. 发明申请

US20090155449A1 MEDICAL DEVICE COATING APPARATUS AND METHODS OF USE 审中-公开
标题翻译：医疗装置涂装装置及其使用方法
公开(公告)号：US20090155449A1
公开(公告)日：2009-06-18
申请号：US11959325
申请日：2007-12-18
申请人： Isaac Plans , David O'Neill , Matthew Coates , Javier P. Moreno
发明人： Isaac Plans , David O'Neill , Matthew Coates , Javier P. Moreno
IPC分类号： B05B13/04 , A61L31/00
CPC分类号： B05D1/02 , B05B7/0807 , B05B13/0228 , B05B13/0442 , B05B15/55 , B05B15/68
摘要： Apparatus and methods are configured to coat a medical device, such as a stent, with a beneficial medicinal agent using one or more liquid feeds and one or more micromist nozzles. In one implementation, an agent coating rig includes a vertical adjustment means, a rotation means, and a traverse adjustment means for moving a medical device along virtually any point on an x or y axis. In additional or alternative implementations, the agent coating rig can further include a secondary horizontal adjustment means that allows adjustment along virtually any point on a z axis. Furthermore, methods and apparatus are provided for distributing the beneficial agent on the medical device, including delivering the beneficial agent efficiently over time.
摘要翻译：设备和方法被配置为使用一种或多种液体进料和一个或多个微型喷嘴将有益药剂涂覆在诸如支架的医疗装置上。在一个实施方案中，试剂涂布装置包括垂直调节装置，旋转装置和用于沿着x或y轴上的任何点移动医疗装置的横动调节装置。在附加或替代实施方案中，代理涂布装置还可以包括允许沿着z轴上的任何点进行调整的次级水平调节装置。此外，提供了将有益药剂分发到医疗装置上的方法和装置，包括有效地递送有益药剂。

2. 发明申请

US20110311713A1 SYSTEMS AND METHODS FOR ROTATING AND COATING AN IMPLANTABLE DEVICE 有权
标题翻译：用于旋转和涂覆可植入设备的系统和方法
公开(公告)号：US20110311713A1
公开(公告)日：2011-12-22
申请号：US12817544
申请日：2010-06-17
申请人： David O'Neill , Matthew Coates
发明人： David O'Neill , Matthew Coates
IPC分类号： B05D7/00 , B05C13/00
CPC分类号： A61F2/07 , A61F2/91 , B05B12/122 , B05B13/0228 , B05B17/0623 , B05D1/002 , B05D1/02 , B05D2254/02 , B05D2254/04
摘要： A method for applying a coating to an implantable device is disclosed. The method includes positioning an implantable device relative to an ultrasonic material delivery apparatus. The implantable device is rotated at a relative speed. The relative speed may be more than 120 revolutions per minute. An application material is applied to the implantable device using the ultrasonic material delivery apparatus. The relative speed may be sufficient to reduce the size of at least a portion of droplets of the application material. A system for rotating an implantable device is disclosed. The system includes an implantable device and a rotation system configured to rotate the implantable device. A longitudinal axis of the implantable device and a longitudinal axis of a rotation member of the rotation system may be offset a desired dimension. An inside diameter of the implantable device may be larger than an outside diameter of a rotation member.
摘要翻译：公开了一种将涂层施加到可植入装置的方法。该方法包括相对于超声波材料输送装置定位可植入装置。可植入装置以相对速度旋转。相对速度可能超过每分钟120转。使用超声波材料输送装置将施加材料施加到可植入装置。相对速度可能足以减小应用材料的至少一部分液滴的尺寸。公开了一种用于旋转可植入装置的系统。该系统包括可植入装置和被配置为旋转可植入装置的旋转系统。可植入装置的纵向轴线和旋转系统的旋转构件的纵向轴线可以偏离期望的尺寸。可植入装置的内径可以大于旋转构件的外径。

3. 发明申请

US20080257061A1 GRIPPING FIXTURE 有权
标题翻译：传送装置
公开(公告)号：US20080257061A1
公开(公告)日：2008-10-23
申请号：US11736447
申请日：2007-04-17
申请人： James Joseph Phelan , Matthew Coates
发明人： James Joseph Phelan , Matthew Coates
IPC分类号： G01N3/08
CPC分类号： G01N3/04 , G01N3/08 , G01N2203/0089 , G01N2203/0278 , G01N2203/028
摘要： A gripping fixture suitable for use in stent securement testing is described. The gripping fixture includes a housing having a chamber, a rigid perforated tubular member positioned within the chamber, a multiplicity of radially extending pins arranged to slide in the perforations in the tubular member, and an elastic sheath that circumscribes the outer ends of the pins and surrounds the tubular member. A pressure chamber is formed between the housing and the elastic sheath. The gripping fixture also includes a pressure controller for controlling the pressure within the pressure chamber. The pressure applied in the pressure chamber acts on the elastic sheath and may be used to cause some of the pins to engage a stent during the stent securement test to hold the stent in place relative to the gripping fixture while the tensile force required to dislodge the stent from a catheter is measured.
摘要翻译：描述适用于支架固定测试的夹具。夹持夹具包括具有腔室的壳体，定位在腔室内的刚性多孔管状构件，多个径向延伸的销，布置成在管状构件中的穿孔中滑动，以及弹性护套，其围绕销的外端; 围绕管状构件。在壳体和弹性护套之间形成压力室。夹持夹具还包括用于控制压力室内的压力的压力控制器。施加在压力室中的压力作用在弹性护套上，并且可以用于在支架固定测试期间使一些销与支架接合，以将支架相对于夹具固定在适当的位置，同时移除测量来自导管的支架。

4. 发明申请

US20130177696A1 SYSTEMS AND METHODS FOR ROTATING AND COATING AN IMPLANTABLE DEVICE 有权
标题翻译：用于旋转和涂覆可植入设备的系统和方法
公开(公告)号：US20130177696A1
公开(公告)日：2013-07-11
申请号：US13781249
申请日：2013-02-28
申请人： David O'Neill , Matthew Coates
发明人： David O'Neill , Matthew Coates
IPC分类号： A61F2/07
CPC分类号： A61F2/07 , A61F2/91 , B05B12/122 , B05B13/0228 , B05B17/0623 , B05D1/002 , B05D1/02 , B05D2254/02 , B05D2254/04
摘要： A method for applying a coating to an implantable device is disclosed. The method includes positioning an implantable device relative to an ultrasonic material delivery apparatus. The implantable device is rotated at a relative speed. The relative speed may be more than 120 revolutions per minute. An application material is applied to the implantable device using the ultrasonic material delivery apparatus. The relative speed may be sufficient to reduce the size of at least a portion of droplets of the application material. A system for rotating an implantable device is disclosed. The system includes an implantable device and a rotation system configured to rotate the implantable device. A longitudinal axis of the implantable device and a longitudinal axis of a rotation member of the rotation system may be offset a desired dimension. An inside diameter of the implantable device may be larger than an outside diameter of a rotation member.
摘要翻译：公开了一种将涂层施加到可植入装置的方法。该方法包括相对于超声波材料输送装置定位可植入装置。可植入装置以相对速度旋转。相对速度可能超过每分钟120转。使用超声波材料输送装置将施加材料施加到可植入装置。相对速度可能足以减小应用材料的至少一部分液滴的尺寸。公开了一种用于旋转可植入装置的系统。该系统包括可植入装置和被配置为旋转可植入装置的旋转系统。可植入装置的纵向轴线和旋转系统的旋转构件的纵向轴线可以偏离期望的尺寸。可植入装置的内径可以大于旋转构件的外径。

5. 发明授权

US08389041B2 Systems and methods for rotating and coating an implantable device 有权
标题翻译：用于旋转和涂覆可植入装置的系统和方法
公开(公告)号：US08389041B2
公开(公告)日：2013-03-05
申请号：US12817544
申请日：2010-06-17
申请人： David O'Neill , Matthew Coates
发明人： David O'Neill , Matthew Coates
IPC分类号： A61L33/00 , B05D3/00 , B05D7/00 , B23Q3/00
CPC分类号： A61F2/07 , A61F2/91 , B05B12/122 , B05B13/0228 , B05B17/0623 , B05D1/002 , B05D1/02 , B05D2254/02 , B05D2254/04
摘要： A method for applying a coating to an implantable device is disclosed. The method includes positioning an implantable device relative to an ultrasonic material delivery apparatus. The implantable device is rotated at a relative speed. The relative speed may be more than 120 revolutions per minute. An application material is applied to the implantable device using the ultrasonic material delivery apparatus. The relative speed may be sufficient to reduce the size of at least a portion of droplets of the application material. A system for rotating an implantable device is disclosed. The system includes an implantable device and a rotation system configured to rotate the implantable device. A longitudinal axis of the implantable device and a longitudinal axis of a rotation member of the rotation system may be offset a desired dimension. An inside diameter of the implantable device may be larger than an outside diameter of a rotation member.
摘要翻译：公开了一种将涂层施加到可植入装置的方法。该方法包括相对于超声波材料输送装置定位可植入装置。可植入装置以相对速度旋转。相对速度可能超过每分钟120转。使用超声波材料输送装置将施加材料施加到可植入装置。相对速度可能足以减小应用材料的至少一部分液滴的尺寸。公开了一种用于旋转可植入装置的系统。该系统包括可植入装置和被配置为旋转可植入装置的旋转系统。可植入装置的纵向轴线和旋转系统的旋转构件的纵向轴线可以偏离期望的尺寸。可植入装置的内径可以大于旋转构件的外径。

6. 发明申请

US20080183271A1 COMPLIANT CRIMPING SHEATH 审中-公开
标题翻译：合适的伤口
公开(公告)号：US20080183271A1
公开(公告)日：2008-07-31
申请号：US11669742
申请日：2007-01-31
申请人： Maire A. Frawley , Matthew Coates
发明人： Maire A. Frawley , Matthew Coates
IPC分类号： A61F2/84 , B21C37/06
CPC分类号： A61F2/958 , A61F2/91 , A61F2002/9522 , A61F2250/0067
摘要： The present invention provides an apparatus and methods for use in crimping a stent. In one embodiment, an arrangement is described that includes a stent delivery device. A stent having a plurality of struts is crimped onto the stent delivery device. The arrangement also includes a crimp sheath that covers at least a portion of the stent. The crimp sheath is formed at least in part from a compliant viscoelastic material. The viscoelastic portions of the crimp sheath protrude into the gaps formed between adjacent crimped struts. In this manner, the viscoelastic portions form protrusions that extend into the gaps to a sufficient depth to prevent the struts from contacting one another. By way of example, in one embodiment, the protrusions extend to a depth of at least 18 percent of the thickness of the associated adjacent struts.
摘要翻译：本发明提供一种用于卷曲支架的装置和方法。在一个实施例中，描述了包括支架输送装置的布置。将具有多个支柱的支架卷曲到支架输送装置上。该布置还包括覆盖支架的至少一部分的卷曲护套。卷曲护套至少部分地由顺应性粘弹性材料形成。卷曲护套的粘弹性部分突出到相邻的压接支柱之间形成的间隙中。以这种方式，粘弹部分形成延伸到间隙中的足够深度的突起，以防止支柱彼此接触。作为示例，在一个实施例中，突起延伸到相关联的相邻支柱的厚度的至少18％的深度。

7. 发明授权

US07552650B2 Gripping fixture 有权
标题翻译：夹具
公开(公告)号：US07552650B2
公开(公告)日：2009-06-30
申请号：US11736447
申请日：2007-04-17
申请人： James Joseph Phelan , Matthew Coates
发明人： James Joseph Phelan , Matthew Coates
IPC分类号： G01N3/02 , G01N3/08 , B66C1/46 , B66C1/54 , B66C1/42
CPC分类号： G01N3/04 , G01N3/08 , G01N2203/0089 , G01N2203/0278 , G01N2203/028
摘要： A gripping fixture suitable for use in stent securement testing is described. The gripping fixture includes a housing having a chamber, a rigid perforated tubular member positioned within the chamber, a multiplicity of radially extending pins arranged to slide in the perforations in the tubular member, and an elastic sheath that circumscribes the outer ends of the pins and surrounds the tubular member. A pressure chamber is formed between the housing and the elastic sheath. The gripping fixture also includes a pressure controller for controlling the pressure within the pressure chamber. The pressure applied in the pressure chamber acts on the elastic sheath and may be used to cause some of the pins to engage a stent during the stent securement test to hold the stent in place relative to the gripping fixture while the tensile force required to dislodge the stent from a catheter is measured.
摘要翻译：描述适用于支架固定测试的夹具。夹持夹具包括具有腔室的壳体，定位在腔室内的刚性多孔管状构件，多个径向延伸的销，布置成在管状构件中的穿孔中滑动，以及弹性护套，其围绕销的外端; 围绕管状构件。在壳体和弹性护套之间形成压力室。夹持夹具还包括用于控制压力室内的压力的压力控制器。施加在压力室中的压力作用在弹性护套上，并且可以用于在支架固定测试期间使一些销与支架接合，以将支架相对于夹具固定在适当的位置，同时移除测量来自导管的支架。

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