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1. 发明申请

US20140231351A1 MAGNETICALLY RESPONSIVE MEMBRANES 有权
标题翻译：磁性反应膜
公开(公告)号：US20140231351A1
公开(公告)日：2014-08-21
申请号：US13570003
申请日：2012-08-08
申请人： Sumith Ranil WICKRAMASINGHE , Xianghong QIAN , Heath H. HIMSTEDT , Mathias ULBRICHT , Michael J. SEMMENS
发明人： Sumith Ranil WICKRAMASINGHE , Xianghong QIAN , Heath H. HIMSTEDT , Mathias ULBRICHT , Michael J. SEMMENS
IPC分类号： B01D71/02 , B01D67/00 , B01D69/14
CPC分类号： B01D67/0079 , B01D65/08 , B01D69/02 , B01D69/10 , B01D69/12 , B01D69/148 , B01D71/40 , B01D71/56 , B01D71/68 , B01D71/78 , B01D2311/2607 , B01D2321/24 , B01D2323/38 , B01D2325/36 , B01D2325/46
摘要： The invention provides permeable magnetically responsive filtration membranes that include a filtration membrane polymer base suitable for fluid filtration; hydrophilic polymers conjugated to the surface of the filtration membrane polymer; and magnetic nanoparticles affixed to the ends of a plurality of the hydrophilic polymers, wherein the hydrophilic polymers are movable with respect to the surface of the filtration membrane polymer surface in the presence of an oscillating magnetic field.
摘要翻译：本发明提供了可渗透的磁响应过滤膜，其包括适于流体过滤的过滤膜聚合物基料; 与过滤膜聚合物的表面共轭的亲水性聚合物; 和固定在多个亲水性聚合物的端部的磁性纳米颗粒，其中亲水性聚合物可以在存在振荡磁场的情况下相对于过滤膜聚合物表面的表面移动。

2. 发明申请

US20100307974A1 PREPARATION AND USE OF NOVEL POLYANILINES FOR WATER TREATMENT 审中-公开
标题翻译：用于水处理的新型聚氨酯的制备和使用
公开(公告)号：US20100307974A1
公开(公告)日：2010-12-09
申请号：US12743620
申请日：2008-11-20
申请人： Karl-Heinz Pettinger , Franz-Xaver Muller , Gerhard Illing , Mathias Ulbricht
发明人： Karl-Heinz Pettinger , Franz-Xaver Muller , Gerhard Illing , Mathias Ulbricht
IPC分类号： C08G75/04 , C08L81/00 , B32B5/02 , B32B1/00 , B32B27/00 , B05D3/02 , B01D53/22 , B03C3/40 , B01D53/02 , B01D71/76 , B01D69/08 , B01D15/04 , B03C5/02 , C02F1/44
CPC分类号： H01M8/20 , A61L9/01 , A61L9/16 , B01D69/10 , B01D71/60 , B01D2257/91 , C02F1/46109 , C02F2001/46138 , C08G73/0266 , C09D179/02 , C09J179/02 , H01M2300/0082 , Y02E60/528 , Y02P70/56 , Y10T428/1352 , Y10T442/10 , Y10T442/20
摘要： The invention relates to a polyaniline, comprising aniline units and organosulphur units, characterized in that the polyaniline is doped and has a number average degree of polymerization of approximately 5 to approximately 50. The scope of the invention also includes a process for the preparation of polyaniline, wherein aniline and at least one organosulphur unit are converted to a polyaniline derivative in an oxidative, acid-catalyzed polymerization reaction. A subject of the invention is also a coated substrate which is coated with the polyaniline according to the invention and also a process for the coating of the substrate. The scope of the invention furthermore also includes a coating composition which is suitable for the coating of the substrate. The invention thus also relates to a process for the preparation of the coating composition. A subject of the invention is also the use of polyaniline which is doped and has sulphur in the main polymer chain for water treatment and/or for the purification of air and also a purification reactor for carrying out the purification process.
摘要翻译：本发明涉及包含苯胺单元和有机硫单元的聚苯胺，其特征在于聚苯胺被掺杂并具有约5至约50的数均聚合度。本发明的范围还包括制备聚苯胺的方法其中苯胺和至少一种有机硫单元在氧化，酸催化的聚合反应中转化为聚苯胺衍生物。本发明的主题也是涂覆有根据本发明的聚苯胺的涂覆基材，以及涂布基材的方法。本发明的范围还包括适合于涂覆基材的涂料组合物。因此，本发明还涉及制备涂料组合物的方法。本发明的主题还是在主要聚合物链中掺杂并具有硫以进行水处理和/或空气纯化以及用于进行纯化过程的纯化反应器的聚苯胺的使用。

3. 发明授权

US06753396B2 Method for producing template-textured materials with high binding specificity and selectivity and utilization of said materials 失效
标题翻译：用于生产具有高结合特异性和所述材料的选择性和利用率的模板织构材料的方法
公开(公告)号：US06753396B2
公开(公告)日：2004-06-22
申请号：US10148819
申请日：2002-09-03
申请人： Mathias Ulbricht , Tatinna Sergeyeva , Heike Matuschewski , Uwe Schedler , Sergey A. Piletsky
发明人： Mathias Ulbricht , Tatinna Sergeyeva , Heike Matuschewski , Uwe Schedler , Sergey A. Piletsky
IPC分类号： C08F22046
CPC分类号： G01N30/482 , B01J20/268 , B01J20/281 , B01J20/3057 , B01J20/3204 , B01J20/321 , B01J20/3212 , B01J20/327 , B01J20/3272 , B01J20/3274 , B01J20/3276 , B01J20/3278 , B01J20/3282 , B01J20/3285 , B01J2220/54
摘要： The invention relates to a method for the production of a template-textured material by synthesis of a template-textured polymer (TTP) by performing crosslinking polymerization of functional monomers on a support in the presence of a template, which method is characterized in that a support having a thin polymer layer on the surface thereof is added with a reaction mixture consisting of polymerization initiator, template, functional monomer, crosslinker, solvent and/or buffer and, following sorption of the reaction mixture in the thin polymer layer, the polymerization is initiated and continued until the absorption capacity of the thin polymer layer for the template-textured polymer (TTP) is reached, and the template is optionally removed in a final step, the support used being selected in such a way that it cannot absorb the reaction solution. The materials of the invention are remarkable for their high binding specificity and selectivity for the template.
摘要翻译：本发明涉及一种通过在模板存在下通过在载体上进行官能单体的交联聚合来通过合成模板织构化聚合物（TTP）来生产模板织构材料的方法，该方法的特征在于，在其表面上具有薄聚合物层的载体中加入由聚合引发剂，模板，官能单体，交联剂，溶剂和/或缓冲剂组成的反应混合物，并且在聚合物层中吸附反应混合物后，聚合反应引发并持续直到达到模板 - 织构聚合物（TTP）的薄聚合物层的吸收能力，并且在最终步骤中任选地除去模板，使用的载体以不能吸收反应的方式进行选择解。本发明的材料对于模板的高结合特异性和选择性是显着的。

4. 发明授权

US06515039B1 Method for the parallel and combinatory synthesis of compounds bound to a continuous polymeric solid phase supporting material 有权
标题翻译：平行和组合合成连接聚合物固相支撑材料的化合物的方法
公开(公告)号：US06515039B1
公开(公告)日：2003-02-04
申请号：US09530457
申请日：2000-06-15
申请人： Mathias Ulbricht , Rudolf Volkmer-Engert , Lothar Germeroth , Holger Wenschuh
发明人： Mathias Ulbricht , Rudolf Volkmer-Engert , Lothar Germeroth , Holger Wenschuh
IPC分类号： C08F246
CPC分类号： C07K1/042 , B01J19/0046 , B01J2219/00585 , B01J2219/00596 , B01J2219/00605 , B01J2219/0061 , B01J2219/00612 , B01J2219/00626 , B01J2219/00637 , B01J2219/00641 , B01J2219/00659 , B01J2219/00722 , C08F255/02 , C08F259/08 , C08F291/18 , C40B40/14
摘要： The invention relates to a method for the parallel and combinatory synthesis of compounds bound to a continuous polymeric solid phase supporting material. According to the method, a continuous polymeric solid phase supporting material is prepared, the material comprising a matrix of a supporting polymeric material and graft copolymer chains covalently bound to the supporting matrix, the graft copolymer chains having reactive groups being able to react with organic compounds, thereby forming spatially defined reaction sites. The method then comprises the sequential spotting of synthesis building blocks or reagents at the various reaction sites on the continuous solid phase supporting material to yield a substrate library of compounds bound to the solid phase supporting material, whereby each reaction site on the continuous solid phase supporting material determines the composition of the synthesized compound, which is bound directly on the supporting matrix via the reactive groups of the graft polymer chain.
摘要翻译：本发明涉及平行和组合合成结合到连续聚合物固相支撑材料上的化合物的方法。根据该方法，制备连续的聚合物固相支撑材料，该材料包含支撑聚合物材料的基体和共价结合到支撑基质上的接枝共聚物链，具有反应性基团的接枝共聚物链能够与有机化合物反应，从而形成空间定义的反应位点。该方法然后包括在连续固相支持材料上的各个反应位点上的合成结构单元或试剂的顺序点样，以产生与固相支持材料结合的化合物的底物文库，由此连续固相支持的每个反应位点材料决定了合成化合物的组成，其通过接枝聚合物链的反应性基团直接结合在载体上。

5. 发明授权

US07153433B2 Use of functionalized porous membranes or matrices for purification of nucleic acids and corresponding methods 失效
标题翻译：使用官能化的多孔膜或基质来纯化核酸和相应的方法
公开(公告)号：US07153433B2
公开(公告)日：2006-12-26
申请号：US10182852
申请日：2001-02-02
申请人： Thomas Kolzau , Heinz Gerhard Köhn , Wilhelm Plüster , Mathias Ulbricht
发明人： Thomas Kolzau , Heinz Gerhard Köhn , Wilhelm Plüster , Mathias Ulbricht
IPC分类号： B01D61/00 , C07H19/04 , C12Q1/68 , B01D63/00
CPC分类号： C12N15/1017
摘要： Application of a functionalized porous membrane to purify nucleic acids, the binding properties of the membrane with respect to nucleic acids being adjustable by controlling the conditions of an ambient medium. The membrane is functionalized by deprotonated groups.
摘要翻译：应用官能化的多孔膜来净化核酸，通过控制环境介质的条件可以调节膜相对于核酸的结合特性。膜由去质子化的基团官能化。

6. 发明授权

US06545144B2 Method for isolating nucleic acids from a liquid sample containing nucleic acids 失效
标题翻译：从含有核酸的液体样品中分离核酸的方法
公开(公告)号：US06545144B2
公开(公告)日：2003-04-08
申请号：US10066509
申请日：2002-01-30
申请人： Thomas Kolzau , Wilhelm Plüster , Mathias Ulbricht
发明人： Thomas Kolzau , Wilhelm Plüster , Mathias Ulbricht
IPC分类号： C07H2100
CPC分类号： C12Q1/6806 , C12N15/1017
摘要： A method for the isolation of nucleic acids from a liquid sample, which contains nucleic acids, using a filtering device, which has pores, through which the sample is allowed to flow in the course of the isolation, the nucleic acids, and contained in the sample, being retained selectively in or at the pores, wherein the sample is mixed with a concentration of the precipitating agent for nucleic acids, which is sufficient to condense the nucleic acids and the sample is then allowed to flow through the filtering device, the pores of the filtering device used having inner wall regions with variable surface structures, which are constructed differently depending on the medium passed through the pores and by which the permeability of the pores can be adjusted between a state, in which the condensed nucleic acid molecules are retained, and a state, in which the dissolved nucleic acid molecules can pass through.
摘要翻译：使用过滤装置从包含核酸的液体样品中分离核酸的方法，所述过滤装置具有孔，允许样品在分离过程中流过其中，并且包含在样品被选择性地保留在孔中或孔中，其中样品与用于核酸的沉淀剂的浓度混合，其足以冷凝核酸，然后允许样品流过过滤装置，孔所使用的过滤装置具有可变表面结构的内壁区域，其根据通过孔的介质而不同地构造，并且可以在冷凝的核酸分子保留的状态之间调节孔的渗透性，以及溶解的核酸分子能够通过的状态。

7. 发明授权

US09132389B2 Magnetically responsive membranes 有权
标题翻译：磁响应膜
公开(公告)号：US09132389B2
公开(公告)日：2015-09-15
申请号：US13570003
申请日：2012-08-08
申请人： Sumith Ranil Wickramasinghe , Xianghong Qian , Heath H. Himstedt , Mathias Ulbricht , Michael J. Semmens
发明人： Sumith Ranil Wickramasinghe , Xianghong Qian , Heath H. Himstedt , Mathias Ulbricht , Michael J. Semmens
IPC分类号： B01D39/00 , B01D39/14 , B01D63/00 , B01D61/00 , B01D67/00 , B01D69/14 , B01D65/08 , B01D69/02 , B01D69/10 , B01D69/12 , B01D71/78 , B01D71/40 , B01D71/56 , B01D71/68
CPC分类号： B01D67/0079 , B01D65/08 , B01D69/02 , B01D69/10 , B01D69/12 , B01D69/148 , B01D71/40 , B01D71/56 , B01D71/68 , B01D71/78 , B01D2311/2607 , B01D2321/24 , B01D2323/38 , B01D2325/36 , B01D2325/46
摘要： The invention provides permeable magnetically responsive filtration membranes that include a filtration membrane polymer base suitable for fluid filtration; hydrophilic polymers conjugated to the surface of the filtration membrane polymer; and magnetic nanoparticles affixed to the ends of a plurality of the hydrophilic polymers, wherein the hydrophilic polymers are movable with respect to the surface of the filtration membrane polymer surface in the presence of an oscillating magnetic field.
摘要翻译：本发明提供了可渗透的磁响应过滤膜，其包括适于流体过滤的过滤膜聚合物基料; 与过滤膜聚合物的表面共轭的亲水性聚合物; 和固定在多个亲水性聚合物的端部的磁性纳米颗粒，其中亲水性聚合物可以在存在振荡磁场的情况下相对于过滤膜聚合物表面的表面移动。

8. 发明授权

US6159370A Solvent and acid resistant membrane on the basis of polyacrylnitrile (PAN) and a comonomer copolymerized therewith and a method of manufacturing such a membrane 有权
标题翻译：基于聚丙烯腈（PAN）和共聚合的共聚单体的溶剂和耐酸膜以及制造这种膜的方法
公开(公告)号：US6159370A
公开(公告)日：2000-12-12
申请号：US265302
申请日：1999-03-09
申请人： Hans-Georg Hicke , Ingeburg Lehmann , Margot Becker , Mathias Ulbricht , Gunter Malsch , Dieter Paul
发明人： Hans-Georg Hicke , Ingeburg Lehmann , Margot Becker , Mathias Ulbricht , Gunter Malsch , Dieter Paul
IPC分类号： C12N11/08 , B01D67/00 , B01D71/42 , C08J5/18
CPC分类号： B01D67/0093 , B01D71/76 , B01D71/40 , B01D71/42
摘要： In a method of making solvent and acid resistant membrane on the basis of polyacrylnitrile (PAN) and a comonomer copolymerized therewith wherein the membrane is formed from a solution by phase inversion, glycidylmethacrylate is used as the comonomer and the membrane formed thereby is then subjected to ammonia.
摘要翻译：在基于聚丙烯腈（PAN）和共聚合的共聚单体制备溶剂和耐酸膜的方法中，其中膜由相转变形成溶液，甲基丙烯酸缩水甘油酯用作共聚单体，然后将由此形成的膜经受氨。

9. 发明申请

US20050053642A1 Biocompatible materials 审中-公开
标题翻译：生物相容性材料
公开(公告)号：US20050053642A1
公开(公告)日：2005-03-10
申请号：US10362677
申请日：2001-08-23
申请人： Mathias Ulbricht , Volkmar Thom , Katja Jankova , George Altankov , Gunnar Jonsson
发明人： Mathias Ulbricht , Volkmar Thom , Katja Jankova , George Altankov , Gunnar Jonsson
IPC分类号： A61L27/34 , A61L27/50 , A61L33/00
CPC分类号： B82Y30/00 , A61L27/34 , A61L27/50 , B82Y5/00
摘要： The present invention teaches a novel approach of creating biocmpatible surfaces, said surfaces being capable of functionally interact with biological material. SAid biocompatible surfaces comrise at least two comonents, such as a hydrophobic substratum and a macromolecule of hydrophilic nature, which, in a cooperativity, form together the novel biocoompatible surfaces. The novel approach is ased on contacting said hydrophobic substratum with a laterally patterned monomolecular layer of said hydrophilic and flexible macromolecules, exhibiting a pronounced excluded volume. The htus formed two component surface is, in respect to polarity and morphology, a molecularly heterogeneous surface. Structural features of said macromolecular monolayer (as e.g. the layer thickness or its lateral density) are determined by: i) the structural features of the layer forming macromolecules (as e.g. their MW or their molecular architecture) and ii) the method of creating said monomolecular layer (as e.g. by physi- or chemisorbing, or by chemically binding said macromolecules). The structural features of the layer forming macromolecules(s) is in turn determined by synthesis. AMount and conformation and thus also biological activity of biological material (as e.g. polypeptides) which contact the novel biocompatible surface, is determined and maintained by the cooperative action of the underlying hydrophobic substratum and the macromolecular layer. In this way it becomes possible to maintain and control biological interactions between said contacted polypeptides and other biological compounds as e.g. cells, antibodies and the like. Consequently, the present invention aims to reduce and/or eliminate the deactivation and/or denaturation associated with the contacting of polypeptides and/or other biological material to a hydrophobic substratum surface.
摘要翻译：本发明教导了一种创建生物相容性表面的新方法，所述表面能够与生物材料进行功能相互作用。所述生物相容性表面至少包含两种共聚物，例如疏水性底物和具有亲水性质的大分子，其以协同作用形成新的生物相容性表面。该新方法是将所述疏水性底物与所述亲水和柔性大分子的横向图案化单分子层接触，表现出显着排除的体积。形成双组分表面的htus在极性和形态方面是分子异质表面。所述大分子单层的结构特征（例如层厚度或其侧向密度）通过以下方式确定：i）形成大分子的层的结构特征（例如它们的MW或其分子结构）和ii）产生所述单分子的方法层（例如通过物理或化学吸附，或通过化学结合所述大分子）。层的形成大分子的结构特征又由合成决定。通过潜在的疏水性底物和大分子层的协同作用确定并保持了与新生物相容性表面接触的生物材料（如多肽）的生物活性和生物学活性。以这种方式，可以维持和控制所述接触的多肽和其他生物化合物之间的生物相互作用，例如。细胞，抗体等。因此，本发明旨在减少和/或消除与多肽和/或其他生物材料与疏水底物表面的接触相关的失活和/或变性。

10. 发明授权

US06670427B1 Template-textured materials, methods for the production and use thereof 失效
标题翻译：模板纹理材料，生产和使用方法
公开(公告)号：US06670427B1
公开(公告)日：2003-12-30
申请号：US09762357
申请日：2001-03-26
申请人： Mathias Ulbricht , Sergiy Piletski , Uwe Schedler , Heike Matuschewski
发明人： Mathias Ulbricht , Sergiy Piletski , Uwe Schedler , Heike Matuschewski
IPC分类号： C08G6348
CPC分类号： B01J20/26 , B01J20/265 , B01J20/267 , B01J20/268 , B01J20/28016 , B01J20/28021 , B01J20/28023 , B01J20/28033 , B01J20/28078
摘要： Template-textured materials in the form of template-textured polymers (TGP) on various surfaces including membranes (i.e, template-textured membranes). Such materials are created by modifying the surface of solid carriers, which, by cross-linking polymerization of functional monomers initiated on the surface of said solid carriers in the presence of a template, leads to stable template prints that subsequently bind template molecules or template derivatives in a specific manner. The invention also relates to methods for the production of TGPs and to the use thereof for substance-specific separation of materials.
摘要翻译：在包括膜（即模板纹理的膜）的各种表面上的模板织构化聚合物（TGP）形式的模板织构材料。这样的材料是通过改变固体载体的表面产生的，其通过在模板存在下在所述固体载体的表面上引发的官能单体的交联聚合，导致稳定的模板印迹，随后结合模板分子或模板衍生物以具体方式。本发明还涉及生产TGP的方法及其用于物质特异性分离材料的用途。

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