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1. 发明授权

US10002501B2 Electronic device 有权
公开(公告)号：US10002501B2
公开(公告)日：2018-06-19
申请号：US13996434
申请日：2011-12-22
申请人： Masatsugu Nakamura , Yasuhiro Ueno
发明人： Masatsugu Nakamura , Yasuhiro Ueno
IPC分类号： G06F3/01 , G08B6/00 , G06F3/041 , G06F3/0488
CPC分类号： G08B6/00 , G06F3/016 , G06F3/0416 , G06F3/0488
摘要： An electronic device includes a display unit 13, a panel 11, a tactile sensation providing unit 12 configured to vibrate a touch face of the panel 11, and a control unit 16 configured, when detecting contact to a tactile sensation providing area of the touch face corresponding to a predetermined word displayed on the display unit 13, to drive the tactile sensation providing unit 12 based on tactile sensation providing information associated with the predetermined word, such that a tactile sensation is provided to a contact object in contact with the tactile sensation providing area.

2. 发明授权

US08865654B2 Eye drops 有权
标题翻译：眼药水
公开(公告)号：US08865654B2
公开(公告)日：2014-10-21
申请号：US13394194
申请日：2010-09-24
申请人： Takahiro Nakamura , Yuichiro Nakada , Takashi Nagano , Masatsugu Nakamura
发明人： Takahiro Nakamura , Yuichiro Nakada , Takashi Nagano , Masatsugu Nakamura
IPC分类号： A61K38/00 , A61P9/10 , A61P27/02 , A61K38/07 , A61K9/00 , C07K5/107 , C07K5/103
CPC分类号： A61K38/07 , A61K9/0048 , C07K5/1013 , C07K5/1016 , A61K2300/00
摘要： An eyedrop containing a peptide having an amino acid sequence represented by Ser-Ser-Ser-Arg (“SSSR”), or a pharmacologically acceptable salt thereof; and a peptide having an amino acid sequence represented by Phe-Gly-Leu-Met-NH2 (“FGLM”), or a pharmacologically acceptable salt thereof. The concentration ratio between SSSR or a pharmacologically acceptable salt thereof and FGLM or a pharmacologically acceptable salt thereof is between 1/15 and 1/50. The concentration of SSSR or a pharmacologically acceptable salt thereof is between 0.001% and 0.3% (w/v) and the concentration of FGLM or a pharmacologically acceptable salt thereof is between 0.015% and 1.5% (w/V). The pH of the eye drop is maintained between 2.5 and 6.5.
摘要翻译：含有具有由Ser-Ser-Ser-Arg（“SSSR”）表示的氨基酸序列的肽或其药理学上可接受的盐的滴眼剂; 和具有由Phe-Gly-Leu-Met-NH 2（“FGLM”）表示的氨基酸序列的肽或其药理学上可接受的盐。 SSSR或其药理学上可接受的盐与FGLM或其药理学上可接受的盐之间的浓度比为1/15至1/50。 SSSR或其药理学上可接受的盐的浓度为0.001％至0.3％（w / v），并且FGLM或其药理学上可接受的盐的浓度为0.015％至1.5％（w / V）。滴眼液的pH值保持在2.5至6.5之间。

3. 发明授权

US08536207B2 Method for treating a keratoconjunctival disorder 失效
标题翻译：治疗角膜结膜疾病的方法
公开(公告)号：US08536207B2
公开(公告)日：2013-09-17
申请号：US13479485
申请日：2012-05-24
申请人： Atsushi Yoshida , Shinichirou Hirai , Masatsugu Nakamura
发明人： Atsushi Yoshida , Shinichirou Hirai , Masatsugu Nakamura
IPC分类号： A61K31/42
CPC分类号： A61K9/0048 , A61K9/06 , A61K9/08 , A61K9/2018 , A61K31/095 , A61K31/26 , Y10S514/912
摘要： A method for treating a keratoconjunctival disorder, wherein the keratoconjunctival disorder comprises at least one disorder selected from the group consisting of a superficial punctate keratopathy, a corneal epithelial defect, corneal erosion, a corneal ulcer, a conjunctival epithelial defect, keratoconjunctivitis sicca, superior limbic keratoconjunctivitis, filamentary keratoconjunctivitis, keratitis and conjunctivitis, and wherein the method comprises orally administering from 3 mg/kg to 30 mg/kg per day of 2-phenyl-1,2-benzisoselenazol-3(2H)-one or a salt thereof to a patient in need thereof.
摘要翻译：一种治疗角膜结膜疾病的方法，其中所述角膜结膜疾病包括至少一种选自浅表性点状角膜病，角膜上皮缺损，角膜侵蚀，角膜溃疡，结膜上皮缺损，圆锥形结膜炎，上颌骨角结膜炎，角膜结膜炎，角膜炎和结膜炎，并且其中所述方法包括将每日3mg / kg至30mg / kg的2-苯基-1,2-苯并异硒唑（3H）酮或其盐口服给予有需要的患者。

4. 发明授权

US07676167B2 Apparatus and method for forming an image with variable processing speed or variable developer mixing speed 有权
标题翻译：用于形成具有可变处理速度或可变显影剂混合速度的图像的装置和方法
公开(公告)号：US07676167B2
公开(公告)日：2010-03-09
申请号：US11783488
申请日：2007-04-10
申请人： Tohru Yoshioka , Shuichi Morikuni , Syohji Tomita , Masatsugu Nakamura
发明人： Tohru Yoshioka , Shuichi Morikuni , Syohji Tomita , Masatsugu Nakamura
IPC分类号： G03G15/08 , G03G15/00
CPC分类号： G03G15/0806 , G03G15/5062
摘要： An apparatus for forming an image according to the present invention includes a coverage rate finder, a developing unit, and a control unit. The coverage rate finder finds the coverage rate of the image. The developing unit holds developer in it and includes a stirring means for stirring the held developer at a stirring speed. The developing unit supplies the stirred developer to a surface of an image carrier. When the apparatus forms the image consecutively on sheets of paper, the control unit changes the stirring speed in proportion to the coverage rate. When the apparatus forms an image with a higher coverage rate consecutively on sheets of paper, the control unit makes the stirring speed higher.
摘要翻译：根据本发明的用于形成图像的装置包括覆盖率检索器，显影单元和控制单元。覆盖率查找器找到图像的覆盖率。显影单元保持其中的显影剂，并且包括用于以搅拌速度搅拌保持的显影剂的搅拌装置。显影单元将搅拌的显影剂供应到图像载体的表面。当设备在纸张上连续地形成图像时，控制单元以与覆盖率成比例地改变搅拌速度。当设备在纸张上连续形成具有较高覆盖率的图像时，控制单元使搅拌速度更高。

5. 发明申请

US20090270474A1 Therapeutic Agent for Keratoconjunctival Disorder 审中-公开
标题翻译：角结膜疾病治疗剂
公开(公告)号：US20090270474A1
公开(公告)日：2009-10-29
申请号：US12085214
申请日：2006-12-06
申请人： Keiichi Shibagaki , Shin-ichiro Hirai , Masatsugu Nakamura
发明人： Keiichi Shibagaki , Shin-ichiro Hirai , Masatsugu Nakamura
IPC分类号： A61K31/4164 , A61P27/02
CPC分类号： A61K9/0048 , A61K31/4178 , C07D409/06
摘要： An object of the present invention is to discover a new use of eprosartan or a salt thereof. Eprosartan or a salt thereof exhibits an excellent improving effect in a corneal disorder model, and therefore is useful as a therapeutic agent for a keratoconjunctival disorder such as dry eyes, corneal ulcer, keratitis, conjunctivitis, superficial punctate keratopathy, corneal epithelial defects, conjunctival epithelial defects, keratoconjunctivitis sicca, superior limbic keratoconjunctivitis and filamentary keratitis.
摘要翻译：本发明的目的是发现依普罗沙坦或其盐的新用途。依普罗沙坦或其盐在角膜障碍模型中表现出优异的改善效果，因此可用作角膜结膜疾病如干眼症，角膜溃疡，角膜炎，结膜炎，浅表点状角膜病，角膜上皮缺损，结膜上皮的治疗剂缺陷，结膜炎角膜结膜炎，上限角膜结膜炎和丝状角膜炎。

6. 发明申请

US20090005317A1 Methods for treating a corneal disorder and promoting skin wound healing 有权
标题翻译：治疗角膜障碍并促进皮肤伤口愈合的方法
公开(公告)号：US20090005317A1
公开(公告)日：2009-01-01
申请号：US11725761
申请日：2007-03-20
申请人： Teruo Nishida , Makoto Inui , Masatsugu Nakamura
发明人： Teruo Nishida , Makoto Inui , Masatsugu Nakamura
IPC分类号： A61K38/08 , A61K38/07 , A61K38/10 , A61P17/00 , A61P27/02
CPC分类号： A61K38/30 , A61K9/0048 , C07K5/1013 , C07K5/1016 , C07K14/65
摘要： A method for treating a corneal disorder or for promoting skin wound healing comprising administering to a patient in need thereof a composition containing pharmaceutically effective amounts of (i) a first peptide comprising an amino acid sequence containing the following consecutive amino acids: Ser-Ser-Ser-Arg (SEQ ID NO: 1), or an analog thereof or a pharmaceutically acceptable salt thereof and (ii) a second peptide comprising an amino acid sequence containing the following consecutive amino acids with a terminal —NH2 group: Phe-Gly-Leu-Met-NH2 (SEQ ID NO: 2), or an analog thereof or a pharmaceutically acceptable salt thereof, together with a pharmaceutically acceptable carrier.
摘要翻译：一种治疗角膜病症或促进皮肤伤口愈合的方法，包括向有需要的患者施用含有药学有效量的组合物（i）包含含有以下连续氨基酸的氨基酸序列的第一肽：Ser-Ser- Ser-Arg（SEQ ID NO：1）或其类似物或其药学上可接受的盐，和（ii）包含具有末端-NH 2基团的下列连续氨基酸的氨基酸序列的第二肽：Phe-Gly- Leu-Met-NH 2（SEQ ID NO：2）或其类似物或其药学上可接受的盐以及药学上可接受的载体。

7. 发明授权

US07348329B2 Therapeutic agent for keratoconjunctival disorder 失效
标题翻译：角膜结膜疾病治疗剂
公开(公告)号：US07348329B2
公开(公告)日：2008-03-25
申请号：US10576402
申请日：2004-10-29
申请人： Masatsugu Nakamura , Shin-ichiro Hirai
发明人： Masatsugu Nakamura , Shin-ichiro Hirai
IPC分类号： A61K31/425 , A61K31/505
CPC分类号： A61K31/517 , A61K9/0048 , A61K31/421
摘要： An object of the present invention is to discover a new medicinal use of 5-[4-[[3-methyl-4-oxo-3,4-dihydro-2-quinazolinyl]methoxy]phenylmethyl]thiazolidine-2,4-dione and N-[(4-methoxyphenoxy)carbonyl]-N-[[4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]phenyl]methyl]glycine. Both of the compounds exert an excellent improving effect on corneal disorder models and is useful as a therapeutic agent for a keratoconjunctival disorder such as dry eyes, corneal ulcer, keratitis, conjunctivitis, superficial punctate keratopathy, corneal epithelial defects, conjunctive epithelial defects, keratoconjunctivitis sicca, superior limbic keratoconjunctivitis and filamentary keratitis.
摘要翻译：本发明的目的是发现5- [4 - [[3-甲基-4-氧代-3,4-二氢-2-喹唑啉基]甲氧基]苯甲基]噻唑烷-2,4-二酮的新药用途和N - [（4-甲氧基苯氧基）羰基] -N - [[4- [2-（5-甲基-2-苯基-4-恶唑基）乙氧基]苯基]甲基]甘氨酸。这两种化合物对角膜障碍模型具有极好的改善作用，可用作干眼症，角膜溃疡，角膜炎，结膜炎，浅表性点状角膜病，角膜上皮缺损，结膜上皮缺损，结膜炎角膜结膜炎等角膜结膜疾病的治疗剂，上限角膜结膜炎和丝状角膜炎。

8. 发明授权

US06965696B1 Image processing device for image region discrimination 失效
标题翻译：用于图像区域识别的图像处理装置
公开(公告)号：US06965696B1
公开(公告)日：2005-11-15
申请号：US09684122
申请日：2000-10-06
申请人： Mitsuru Tokuyama , Masatsugu Nakamura , Mihoko Tanimura , Masaaki Ohtsuki , Norihide Yasuoka
发明人： Mitsuru Tokuyama , Masatsugu Nakamura , Mihoko Tanimura , Masaaki Ohtsuki , Norihide Yasuoka
IPC分类号： H04N1/40 , G06T5/00 , G06T5/20 , G06T7/00 , G06T7/40 , G06T7/60
CPC分类号： H04N1/40062 , G06K9/00456 , G06T7/12 , G06T2207/10008
摘要： An image processing device of the present invention is provided with four kinds of sub masks in total including two kinds in a main scanning direction and two kinds in a sub scanning direction, in a main mask constituted by a plurality of pixels including a target pixel. In the image display device, when determining a target pixel of an inputted image data, a difference in a total density of the two kinds of sub masks in a main scanning direction is added to a normalized difference in total density of the two kinds of sub masks in a sub scanning direction, and a resultant value is compared with a threshold value so as to determine if the target pixel is an edge area or not.
摘要翻译：在由包括目标像素的多个像素构成的主掩模中，本发明的图像处理装置设置有总共包括主扫描方向两种和副扫描方向两种的副掩模。在图像显示装置中，当确定输入的图像数据的目标像素时，将主扫描方向上的两种子掩模的总密度差加到两种子像素的总密度的归一化差掩模，并将结果值与阈值进行比较，以确定目标像素是否为边缘区域。

9. 发明授权

US06266156B1 Area judging apparatus 失效
标题翻译：区域判断装置
公开(公告)号：US06266156B1
公开(公告)日：2001-07-24
申请号：US09136226
申请日：1998-08-19
申请人： Mihoko Tanimura , Mitsuru Tokuyama , Masatsugu Nakamura , Masaaki Ohtsuki
发明人： Mihoko Tanimura , Mitsuru Tokuyama , Masatsugu Nakamura , Masaaki Ohtsuki
IPC分类号： G06K1502
CPC分类号： H04N1/40062
摘要： The read out image data is stored in the mask memory in a predetermined mask unit, and binarized into binary value with a predetermined threshold in the binarizing circuit. The binarized image data is output to the main scanning direction-black pixel counting circuit and the sub scanning direction-black pixel counting circuit, respectively, to count black pixels in the main scanning direction and in the sub scanning direction, respectively. The largest value is determined by the comparator, and designated as the linkage degree. With the judging circuit, the area judgement of the character area, the photograph area and the dot area is performed based on the linkage degree.
摘要翻译：读出的图像数据以预定的掩模单位存储在掩模存储器中，并且在二值化电路中被二值化为具有预定阈值的二进制值。将二值化图像数据分别输出到主扫描方向黑色像素计数电路和副扫描方向黑色像素计数电路，以分别对主扫描方向和副扫描方向上的黑色像素进行计数。最大值由比较器确定，并被指定为联动度。利用判断电路，基于连动度进行字符区域，照片区域和点区域的区域判断。

10. 发明授权

US5748794A Image processing device 失效
标题翻译：图像处理装置
公开(公告)号：US5748794A
公开(公告)日：1998-05-05
申请号：US449542
申请日：1995-05-24
申请人： Hiroshi Maeda , Tatsuya Itoh , Masatsugu Nakamura
发明人： Hiroshi Maeda , Tatsuya Itoh , Masatsugu Nakamura
IPC分类号： H04N1/40 , H04N1/409
CPC分类号： H04N1/4092 , H04N1/40087
摘要： An image processing apparatus and method which can be selectively used in a variable mode and a fixed mode. In the variable mode, the quantizing values and thresholds for converting high valued image gradation into low valued image gradation can be changed so as to vary the surface gray levels of a printable image at a fixed laser gradation value. In the fixed mode, constant thresholds and quantizing values are used. The use of selectable operation modes enables easy printing operation with increased quality. Also, constant quality of printable images despite environmental changes may be realized by sensing and comparing currently read reference data with initially stored reference data and subsequently correcting quantizing values and thresholds in accordance with the compared result.
摘要翻译：可以选择性地以可变模式和固定模式使用的图像处理装置和方法。在可变模式中，可以改变用于将高值图像灰度转换为低值图像灰度的量化值和阈值，以便以固定的激光灰度值改变可打印图像的表面灰度级。在固定模式下，使用恒定阈值和量化值。使用可选择的操作模式可以轻松实现打印操作，提高质量。此外，尽管环境变化，可以通过感测和比较当前读取的参考数据与最初存储的参考数据并随后根据比较的结果校正量化值和阈值来实现可打印图像的恒定质量。

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