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    • 4. 发明授权
    • Solenoid apparatus
    • 电磁装置
    • US08344837B2
    • 2013-01-01
    • US13216662
    • 2011-08-24
    • Masami NiimiKouji KatahiraMasaki Akiyama
    • Masami NiimiKouji KatahiraMasaki Akiyama
    • H01F7/08H01H5/00
    • H01H51/065H01F5/04
    • In a solenoid apparatus, first and second cylindrical holding parts respectively have first and second opening parts. One flange part is provided with first and second notch portions. In an exciting coil, one line end portion is held by the first cylindrical holding part, and is bent immediately after the one line end portion is pulled from the first notch portion to the inside of the flange part. A line member is wound around a winding drum part toward the other side in the circumferential direction opposed to the opening direction of the first opening part and is wound a predetermined number of turns. Thereafter, the other line end portion is bent in the axial direction immediately in front of the second notch portion and is pulled out from the second notch portion to the outside of the flange part, and is then held by the second cylindrical holding part.
    • 在螺线管装置中,第一和第二圆柱形保持部分别具有第一和第二开口部分。 一个凸缘部分设置有第一和第二切口部分。 在一个励磁线圈中,一个线端部由第一圆柱形保持部分保持,并且在一个线端部从第一切口部分拉到凸缘部分的内部之后立即弯曲。 线圈构件在与第一开口部的开口方向相反的圆周方向上朝向另一侧卷绕在卷绕鼓部上,并且卷绕预定数量的匝数。 此后,另一个线端部在轴向方向上立即在第二切口部分的前方弯曲,并从第二切口部分拉出到凸缘部分的外侧,然后被第二圆柱形保持部分保持。
    • 7. 发明申请
    • Method of using adenoviral vectors with increased persistence in vivo
    • 使用体内持续性增加的腺病毒载体的方法
    • US20060140909A1
    • 2006-06-29
    • US11208405
    • 2005-08-19
    • Thomas WickhamMasaki AkiyamaJason Gall
    • Thomas WickhamMasaki AkiyamaJason Gall
    • A61K48/00C12N15/861
    • C12N15/86A61K48/00C12N2710/10322C12N2710/10343C12N2710/10345C12N2810/405C12N2810/50
    • The invention provides a method of expressing an exogenous nucleic acid in a mammal. The method comprises slowly releasing into the bloodstream a dose of replication-deficient or conditionally-replicating adenoviral vector having reduced ability to transduce mesothelial cells and hepatocytes. The normalized average bloodstream concentration of the adenovirus over 24 hours post-administration is at least about 1%. Alternatively, the normalized average bloodstream concentration over 24 hours post-administration is at least about 5-fold greater than the normalized average bloodstream concentration for an equivalent dose of a wild-type adenoviral vector. A method of destroying tumor cells in a mammal also is provided, as is a replication-deficient adenoviral vector comprising a serotype 5 or serotype 35 adenoviral genome with a serotype 41 fiber protein, wherein the replication-deficient adenoviral vector exhibits reduced native binding to integrins.
    • 本发明提供了在哺乳动物中表达外源核酸的方法。 该方法包括缓慢释放一定剂量的复制缺陷型或条件复制型腺病毒载体,其具有降低转导间皮细胞和肝细胞的能力。 给药后24小时内腺病毒的归一化平均血流浓度为至少约1%。 或者,给药后24小时内的标准化平均血流浓度比相当剂量的野生型腺病毒载体的归一化平均血流浓度高至少约5倍。 还提供了破坏哺乳动物肿瘤细胞的方法,以及包含血清型5或具有血清型41纤维蛋白的血清型35腺病毒基因组的复制缺陷型腺病毒载体,其中复制缺陷型腺病毒载体表现出降低的天然与整联蛋白结合 。
    • 8. 发明授权
    • Method for removing NOx
    • NOx去除方法
    • US06423283B1
    • 2002-07-23
    • US09623797
    • 2000-09-08
    • Masayoshi IchikiMasaki AkiyamaAtsushi Fukuju
    • Masayoshi IchikiMasaki AkiyamaAtsushi Fukuju
    • B01J800
    • B01D53/8625Y02A50/2345Y02C20/10
    • The invention provides a process for removing NOx which is free of impairment in denitration efficiency at a reaction temperature of up to 300° C. even when the component molar ratio of NOx in the gas to be treated is NO2>NO. For use in removing NOx from the gas to be treated and containing NO2 in a larger amount than NO, that is, having a (NO2)/NOx ratio in excess of 0.5, by selective reduction with use of ammonia serving as a main reducing agent in the presence of a denitration catalyst, the process of the invention for removing NOx comprises adding to the denitration reaction system a substance for removing an excess of oxygen accumulating on catalyst active sites by selectively reducing the oxygen at not higher than 300° C., for example, at 300 to 150° C., in other words, a substance which reacts with the excess of oxygen on the catalyst active sites and becomes oxidized at not higher than 300° C.
    • 本发明提供一种除去在300℃以下的反应温度下脱硝效率不受损害的NOx的方法,即使待处理气体中的NOx的成分摩尔比为NO2> NO。 用于从待处理的气体中除去NO含量大于NO的NO 2,即NO 2 / NOx比超过0.5时,通过使用氨作为主要还原剂进行选择性还原 在脱硝催化剂的存在下,本发明除去NOx的方法包括向脱硝反应体系中加入一种物质,用于通过选择性地将氧气在不高于300℃下还原,除去积聚在催化剂活性位上的过量氧, 例如,在300〜150℃,换句话说,与催化剂活性部位上的过量氧反应并在不高于300℃下氧化的物质。