专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20140046280A1 LIQUID MEDICAMENT APPLICATOR 审中-公开
标题翻译：液体药剂师
公开(公告)号：US20140046280A1
公开(公告)日：2014-02-13
申请号：US14112992
申请日：2012-04-13
申请人： Tomoko Uno , Takashi Hayashi , Yasuhiro Harada , Masahiro Tajima
发明人： Tomoko Uno , Takashi Hayashi , Yasuhiro Harada , Masahiro Tajima
IPC分类号： A61M35/00
CPC分类号： A61M35/003 , A45D34/04
摘要： The present invention provides an applicator, which holds an intended quantity of liquid medicament and applies the same to skin or mucous membrane without wasting. The applicator comprises a grip portion 10 for grasping; a neck portion 12, which can be elastically deflected, continuous from the grip portion 10; and a head portion 13, having a slit 14 for holding the liquid medicament supplied, continuous from the neck portion 12. When the head portion 13 is pressed against the skin or the mucous membrane, the liquid medicament is applied there while the neck portion 12 is elastically deflected.
摘要翻译：本发明提供了一种施用器，其保持预定量的液体药物并将其施用于皮肤或粘膜而不浪费。涂抹器包括用于抓握的握持部分10; 颈部12可从手柄部分10弹性偏转连续; 以及头部13，其具有狭缝14，用于保持从颈部12连续供应的液体药物。当头部13被压靠在皮肤或粘膜上时，液体药物被施加到颈部12 弹性偏转。

2. 发明申请

US20090298928A1 COMPOSITION AND METHOD FOR SCALP AND HAIR TREATMENT 审中-公开
标题翻译： SCALP和头发治疗的组合物和方法
公开(公告)号：US20090298928A1
公开(公告)日：2009-12-03
申请号：US12534775
申请日：2009-08-03
申请人： Masato Iino , Satoshi Yamaki , Satoshi Nakanishi , Masahiro Tajima , Ryuji Ueno
发明人： Masato Iino , Satoshi Yamaki , Satoshi Nakanishi , Masahiro Tajima , Ryuji Ueno
IPC分类号： A61K31/351 , A61P17/00
CPC分类号： C07D319/06 , A61K8/365 , A61K8/37 , A61K8/4973 , A61K8/498 , A61K9/0014 , A61K9/06 , A61K47/10 , A61Q5/006 , A61Q7/00 , C07C69/734 , C07D317/30
摘要： Provided is a composition for scalp and hair treatment, comprising a menthol derivative and a prostaglandin compound having two hetero atoms at the 15 position. The composition of the present invention is effective not only for preventing dandruff and itchy scalp but also for preventing or treating hair loss, baldness, or hair thinness.
摘要翻译：本发明提供一种用于头皮和头发处理的组合物，其包含薄荷醇衍生物和在15位具有两个杂原子的前列腺素化合物。本发明的组合物不仅有效防止头皮屑和瘙痒的头皮，而且有效地防止或治疗脱发，秃发或毛发的变细。

3. 发明授权

US07285294B2 Hair growth inhibitors and composition containing same 失效
标题翻译：毛发生长抑制剂和含有它们的组合物
公开(公告)号：US07285294B2
公开(公告)日：2007-10-23
申请号：US11105523
申请日：2005-04-14
申请人： Akihiro Ishino , Tomoko Yokoyama , Takanari Tsuda , Chika Hamada , Daigo Mizumoto , Masahiro Tajima
发明人： Akihiro Ishino , Tomoko Yokoyama , Takanari Tsuda , Chika Hamada , Daigo Mizumoto , Masahiro Tajima
IPC分类号： A01N65/00 , A61Q7/02 , A61K36/71 , A61K36/78 , A61K8/00
CPC分类号： A61K8/0212 , A61K8/97 , A61Q7/02 , A61Q19/00
摘要： A hair growth inhibitor contains, as an active ingredient, at least one herb selected from the group consisting of phellodendron bark, houttuynia, rice bran, mulberry tree bark, Japanese coptis, thyme, peach seed, nettle, calendula, wild rose and balm mint or the extract thereof and various skin external application compositions such as cosmetic compositions to be used on the outer skin is prepared by mixing these active ingredients with other aqueous phase ingredients and oil phase ingredients according to conventional-methods.
摘要翻译：毛发生长抑制剂含有至少一种选自由黄柏树皮，鱼腥草，米糠，桑树皮，日本黄连，百里香，桃子，荨麻，金盏花，野玫瑰和香草薄荷组成的组的活性成分。通过根据常规方法将这些活性成分与其它水相成分和油相成分混合来制备外皮上使用的化妆品组合物或其提取物和各种皮肤外用施用组合物如化妆品组合物。

4. 发明授权

US06204264B1 Benzimidazole derivative, hair growth promoter and external composition for skin using the same 失效
标题翻译：苯并咪唑衍生物，毛发生长促进剂和皮肤外用组合物
公开(公告)号：US06204264B1
公开(公告)日：2001-03-20
申请号：US09398200
申请日：1999-09-17
申请人： Koji Kobayashi , Hirotada Fukunishi , Kenichi Umishio , Masahiro Tajima
发明人： Koji Kobayashi , Hirotada Fukunishi , Kenichi Umishio , Masahiro Tajima
IPC分类号： A61R31535
CPC分类号： C07D235/24 , A61K8/4946 , A61Q7/00 , C07D235/08
摘要： A benzimidazole derivative or a salt thereof expressed by the following Formula (I): wherein one of A and B is a hydrocarbon group of C10-30 expressed by R1 and the other is —(CH2)n—NR2R3; R2 and R3 individually represent H, lower alkyl, phenyl or benzyl, or —NR2R3 may be a heterocycle having 3-7 members, or —CONR5—(CH2)n—NR2R3 may be the following Group (W): wherein R2 is H, lower alkyl, phenyl or benzyl and ring E is a heterocycle of 6 or 7 members; R4 is selected from the group consisting of H, halogen, cyano, trifluoromethyl, lower alkyl and etc.; R5 is H, lower alkyl, lower acyl or lower alkylcarbamoyl; m is 0 or 1; and n is an integer of 0-5. The benzimidazole derivative or the salt thereof has excellent hair growth and regrowth promoting effects, which are useful for care, improvement or prevention of hair loss in mammals and, in particular, in human.
摘要翻译：由下式（I）表示的苯并咪唑衍生物或其盐：其中A和B中的一个是由R 1表示的C 10-30的烃基，而另一个是 - （CH 2）n -NR 2 R 3; R 2和R 3各自表示H，低级烷基，苯基或苄基，或-NR 2 R 3可以是具有3-7个成员的杂环，或-CONR 5 - （CH 2）n -NR 2 R 3可以是下列基团（W）：其中R 2是H 苯基或苄基，环E是6或7个成员的杂环; R4选自H，卤素，氰基，三氟甲基，低级烷基等; R5是H，低级烷基，低级酰基或低级烷基氨基甲酰基; m为0或1; n为0-5的整数。苯并咪唑衍生物或其盐具有优异的毛发生长和再生长促进作用，其可用于哺乳动物，特别是人的护发，改善或预防脱发。

5. 发明授权

US6114325A 1,2-di-substituted benzene-carboxamide derivative, hair growth promoter and external composition for skin using the same 有权
公开(公告)号：US6114325A
公开(公告)日：2000-09-05
申请号：US176947
申请日：1998-10-22
申请人： Hirotada Fukunishi , Kenichi Umishio , Masahiro Tajima , Koji Kobayashi
发明人： Hirotada Fukunishi , Kenichi Umishio , Masahiro Tajima , Koji Kobayashi
IPC分类号： A61K8/42 , A61K8/44 , A61K8/49 , A61Q5/00 , A61Q5/02 , A61Q7/00 , A61Q19/00 , C07C235/46 , C07C235/84 , C07C237/34 , C07C271/20 , C07C275/54 , C07C281/02 , C07D233/61 , C07D243/08 , C07D295/088 , C07D295/13 , C07D295/192 , C07D295/205 , C07D295/28 , A61K31/495 , A61K31/5513 , C07D241/04
CPC分类号： C07D295/32 , A61K8/42 , A61K8/44 , A61K8/49 , A61K8/4926 , A61K8/494 , A61Q7/00 , C07C235/46 , C07C235/84 , C07C237/34 , C07C271/20 , C07C275/54 , C07C281/02 , C07D243/08 , C07D295/088 , C07D295/13 , C07D295/192 , C07D295/205 , A61Q5/02
摘要： A 1,2-di-substituted benzene-carboxamide derivative or a salt thereof expressed by the following Formula (I); ##STR1## wherein each of A and B is R.sup.1 or --(CH.sub.2)n-NR.sup.2 R.sup.3, wherein when A is R.sup.1, B is --(CH.sub.2)n-NR.sup.2 R.sup.3 and when A is --(CH.sub.2)n-NR.sup.2 R.sup.3, B is R.sup.1 ; Z is --O--, --OCO--, --OCONR.sup.6 -- or --NR.sup.6 --; R.sup.1 is a hydrocarbon group of C.sub.10-30 ; R.sup.2 and R.sup.3 individually represent a hydrogen atom, a lower alkyl group, a phenyl group or a benzyl group, or together represent a heterocyclic ring having 3-7 members; when A is --(CH.sub.2)n-NR.sup.2 R.sup.3, R.sup.2 may be a hydrogen atom, a lower alkyl group, a phenyl group or a benzyl group, and R.sup.3 and R.sup.5 together may represent a heterocyclic ring of 6 or 7 members including two nitrogen atoms; when --Z--B is --OCONR.sup.6 --(CH.sub.2)n-NR.sup.2 R.sup.3 or --NR.sup.6 --(CH.sub.2)n-NR.sup.2 R.sup.3, R.sup.2 may be a hydrogen atom, a lower alkyl group, a phenyl group or a benzyl group, and R.sup.3 and R.sup.6 together may represent a heterocyclic ring of 6 or 7 members including two nitrogen atoms; R.sup.4 is selected from the group consisting of a halogen atom, a lower alkyl group, a lower acyl group, a nitro group, a cyano group, a lower alkoxycarbonyl group, a carbamoyl group, a lower alkylcarbamoyl group, a lower alkylamino group, a lower acylamino group, a lower alkoxy group and a lower acyloxy group; R.sup.5 is a hydrogen atom, a lower alkyl group, a lower acyl group or a lower alkylcarbamoyl group, or when A is --(CH.sub.2)n-NR.sup.2 R.sup.3, R.sup.5 and R.sup.3 together may represent a heterocyclic ring of 6 or 7 members including two nitrogen atoms; R.sup.6 is a hydrogen atom, a lower alkyl group, a lower acyl group or a lower alkylcarbamoyl group, or when --Z--B is --OCONR.sup.6 --(CH.sub.2)n-NR.sup.2 R.sup.3 or --NR.sup.6 --(CH.sub.2)n-NR.sup.2 R.sup.3, R.sup.6 and R.sup.3 together may represent a heterocyclic ring of 6 or 7 members including two nitrogen atoms; l is an integer of 0-2; and n is an integer of 0-5. The 1,2-di-substituted benzene-carboxamide derivative or the salt thereof has excellent hair growth and regrowth promoting effects, which are useful for care, improvement or prevention of hair loss in mammals and, in particular, in humans.

6. 发明授权

US6017533A Peptides having specific affinity to pituitary adenylate cyclase activating polypeptide type 1 receptors 失效
标题翻译：对垂体腺苷酸环化酶活化多肽1型受体具有特异性亲和力的肽
公开(公告)号：US6017533A
公开(公告)日：2000-01-25
申请号：US637437
申请日：1996-04-25
申请人： Osamu Moro , Kawori Wakita , Manami Ohnuma , Ethan A. Lerner , Masahiro Tajima
发明人： Osamu Moro , Kawori Wakita , Manami Ohnuma , Ethan A. Lerner , Masahiro Tajima
IPC分类号： G01N33/566 , A61K38/00 , C07K14/47 , C07K14/575 , G01N33/68 , A61K39/00 , C07K2/00 , C07K5/00 , G01N33/567
CPC分类号： G01N33/6842 , C07K14/47 , C07K14/57563 , G01N33/68 , A61K38/00
摘要： This specification relates to the use of peptides having a specific affinity to pituitary adenylate cyclase activating polypeptide (PACAP) receptors, particularly MAX (67 amino acids), NSP (61 amino acids) and M65 (46 amino acids). MAX and NSP act as agonists to PACAP type 1 receptors, and M65 acts as an antagonist to PACAP type 1 receptors.
摘要翻译：本说明书涉及对垂体腺苷酸环化酶活化多肽（PACAP）受体，特别是MAX（67个氨基酸），NSP（61个氨基酸）和M65（46个氨基酸）具有特异亲和力的肽的用途。 MAX和NSP作为PACAP 1型受体的激动剂，M65作为PACAP 1型受体的拮抗剂。

7. 发明授权

US5993855A Delayed drug-releasing microspheres 失效
标题翻译：延迟药物释放微球
公开(公告)号：US5993855A
公开(公告)日：1999-11-30
申请号：US710648
申请日：1996-09-18
申请人： Takashi Yoshimoto , Masahiro Tajima , Kazuo Watabe
发明人： Takashi Yoshimoto , Masahiro Tajima , Kazuo Watabe
IPC分类号： A61K9/00 , A61K9/16 , A61K9/52 , A61K38/00 , A61K38/22 , A61K38/23 , A61K47/34 , A61P9/08 , B01J13/12 , A61K9/14
CPC分类号： A61K9/0085 , A61K38/1767 , A61K38/225 , A61K9/1647
摘要： Microspheres prepared by emulsifying an aqueous phase containing a drug and an oil phase containing a biodegradable polymer to form a W/O emulsion, and then mixing and agitating this emulsion with another aqueous phase constituting a continuous phase to form a W/O/W emulsion. These microspheres can release a major portion of the drug after a predetermined period of time has elapsed after their administration to the patient, and are especially suitable for intracerebral implantation.
摘要翻译：通过乳化包含药物的水相和含有可生物降解聚合物的油相以形成W / O乳液制备的微球，然后将该乳液与构成连续相的另一水相混合并搅拌以形成W / O / W乳液。这些微球体在给予患者之后经过预定的时间后能释放大部分药物，特别适用于脑内植入。

8. 发明申请

US20120088823A1 COMPOSITION AND METHOD FOR SCALP AND HAIR TREATMENT 审中-公开
标题翻译： SCALP和头发治疗的组合物和方法
公开(公告)号：US20120088823A1
公开(公告)日：2012-04-12
申请号：US13329639
申请日：2011-12-19
申请人： Masato IINO , Satoshi YAMAKI , Satoshi NAKANISHI , Masahiro TAJIMA , Ryuji UENO
发明人： Masato IINO , Satoshi YAMAKI , Satoshi NAKANISHI , Masahiro TAJIMA , Ryuji UENO
IPC分类号： A61K31/357 , A61P17/14 , A61K31/215
CPC分类号： C07D319/06 , A61K8/365 , A61K8/37 , A61K8/4973 , A61K8/498 , A61K9/0014 , A61K9/06 , A61K47/10 , A61Q5/006 , A61Q7/00 , C07C69/734 , C07D317/30
摘要： Provided is a composition for scalp and hair treatment, comprising a menthol derivative and a prostaglandin compound having two hetero atoms at the 15 position. The composition of the present invention is effective not only for preventing dandruff and itchy scalp but also for preventing or treating hair loss, baldness, or hair thinness.
摘要翻译：本发明提供一种用于头皮和头发处理的组合物，其包含薄荷醇衍生物和在15位具有两个杂原子的前列腺素化合物。本发明的组合物不仅对防止头皮屑和瘙痒的头皮也有效，而且对于防止或治疗脱发，秃发或毛发变薄是有效的。

9. 发明申请

US20070298134A1 Composition and Method for Scalp and Hair Treatment 审中-公开
标题翻译：头皮和头发处理的组成和方法
公开(公告)号：US20070298134A1
公开(公告)日：2007-12-27
申请号：US11794120
申请日：2005-12-28
申请人： Masato Iino , Satoshi Yamaki , Satoshi Nakanishi , Masahiro Tajima , Ryuji Ueno
发明人： Masato Iino , Satoshi Yamaki , Satoshi Nakanishi , Masahiro Tajima , Ryuji Ueno
IPC分类号： A61K36/534 , A61Q5/00 , A61Q7/00
CPC分类号： C07D319/06 , A61K8/365 , A61K8/37 , A61K8/4973 , A61K8/498 , A61K9/0014 , A61K9/06 , A61K47/10 , A61Q5/006 , A61Q7/00 , C07C69/734 , C07D317/30
摘要： Provided is a composition for scalp and hair treatment, comprising a menthol derivative and a prostaglandin compound having two hetero atoms at the 15 position. The composition of the present invention is effective not only for preventing dandruff and itchy scalp but also for preventing or treating hair loss, baldness, or hair thinness.
摘要翻译：本发明提供一种用于头皮和头发处理的组合物，其包含薄荷醇衍生物和在15位具有两个杂原子的前列腺素化合物。本发明的组合物不仅对防止头皮屑和瘙痒的头皮也有效，而且对于防止或治疗脱发，秃发或毛发变薄是有效的。

10. 发明授权

US5612454A Process for purification of polypeptide using a buchner funnel 失效
标题翻译：使用布氏漏斗纯化多肽的方法
公开(公告)号：US5612454A
公开(公告)日：1997-03-18
申请号：US776272
申请日：1991-11-29
申请人： Toshihiko Kaminuma , Toshii Iida , Masahiro Tajima
发明人： Toshihiko Kaminuma , Toshii Iida , Masahiro Tajima
IPC分类号： C07K1/16 , C07K1/36 , A61K38/00 , A61K38/02 , C07K1/00 , C07K5/00
CPC分类号： C07K1/16 , C07K1/36
摘要： An improved process for purifying a polypeptide using a packing material for reversed phase high performance liquid chromatography is provided. A process for purifying a polypeptide characterized in that an aqueous solution containing polypeptide obtained by pre-treating a polypeptide produced by a wide variety of cells to a predetermined state is adjusted to a specific pH value, to remove impurities, and is then treated with a packing material for reversed phase high performance liquid chromatography.
摘要翻译： PCT No.PCT / JP91 / 00421 Sec。 371日期：1991年11月29日 102（e）1991年11月29日PCT PCT 1991年3月29日PCT。公开号WO91 / 15502 日期1991年10月17日提供了一种使用反相高效液相色谱法的填充材料纯化多肽的改进方法。一种纯化多肽的方法，其特征在于，将通过将由多种细胞产生的多肽预处理至预定状态而获得的含有多肽的水溶液调节至特定的pH值以除去杂质，然后用用于反相高效液相色谱的包装材料。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式