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1. 发明申请

US20070148731A9 Efficient protein expression system 失效
标题翻译：高效蛋白表达系统
公开(公告)号：US20070148731A9
公开(公告)日：2007-06-28
申请号：US11209589
申请日：2005-08-22
申请人： Mary Hu
发明人： Mary Hu
IPC分类号： C12Q1/68 , C07H21/04 , C12N1/21 , C07K14/24 , C12N15/74
CPC分类号： C12N15/70 , A61K39/00 , A61K2039/505 , C07K14/315 , C07K2319/00 , Y10S530/806 , Y10S530/825
摘要： Nucleic acid expression control sequence cassettes and vectors containing the same are provided for use in making abundant quantities of recombinant polypeptides of interest. The modified transcriptional control sequences, which include a T5 promoter sequence, are highly stable and can be used in a variety of vectors, such as plasmids.
摘要翻译：提供了核酸表达控制序列盒和含有其的载体，用于制备大量感兴趣的重组多肽。包括T5启动子序列的修饰的转录控制序列是高度稳定的并且可以用于多种载体，例如质粒。

2. 发明申请

US20060286124A1 Vaccine compositions and methods of treating coronavirus infection 审中-公开
标题翻译：疫苗组合物和治疗冠状病毒感染的方法
公开(公告)号：US20060286124A1
公开(公告)日：2006-12-21
申请号：US11173793
申请日：2005-06-30
申请人： David Burt , Mark Reddish , Mary Hu , George Lowell , David Jones
发明人： David Burt , Mark Reddish , Mary Hu , George Lowell , David Jones
IPC分类号： A61K39/215 , C12Q1/70 , C07H21/04 , C12P21/06 , C12N15/86 , C07K14/165
CPC分类号： A61K39/215 , A61K39/12 , A61K2039/543 , A61K2039/55511 , A61K2039/55516 , A61K2039/55572 , A61K2039/57 , C07K14/005 , C12N2770/20022 , C12N2770/20034
摘要： The present disclosure relates to compositions and methods for treating or preventing coronavirus infections. For example, compositions are provided that comprise a coronavirus S protein or N protein, fragment, or variant thereof, capable of eliciting a protective humoral and/or cell-mediated immune response, which compositions are useful for treating or preventing infection by coronavirus, such as the causative agent of SARS. Also, coronavirus S protein and N protein immunogen compositions are provided that include an adjuvant, such as Proteosome or Protollin, which may be used for treating or preventing infection caused by a coronavirus, such as a SARS coronavirus.
摘要翻译：本公开涉及用于治疗或预防冠状病毒感染的组合物和方法。例如，提供了包含能够引发保护性体液和/或细胞介导的免疫应答的冠状病毒S蛋白或N蛋白，片段或变体的组合物，该组合物可用于治疗或预防冠状病毒感染，例如作为SARS的病因。此外，提供冠状病毒S蛋白和N蛋白免疫原组合物，其包括佐剂，例如Proteosome或Protollin，其可用于治疗或预防冠状病毒如SARS冠状病毒引起的感染。

3. 发明申请

US20050287642A1 Efficient protein expression system 失效
公开(公告)号：US20050287642A1
公开(公告)日：2005-12-29
申请号：US11209589
申请日：2005-08-22
申请人： Mary Hu
发明人： Mary Hu
IPC分类号： C12N15/09 , A61K38/00 , A61K39/00 , A61K39/395 , A61P31/04 , A61P37/02 , C07K14/185 , C07K14/315 , C07K16/12 , C07K19/00 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/70 , C12P21/02 , C12Q1/68 , C07H21/04 , C07K14/24 , C12N15/74
CPC分类号： C12N15/70 , A61K39/00 , A61K2039/505 , C07K14/315 , C07K2319/00 , Y10S530/806 , Y10S530/825
摘要： Nucleic acid expression control sequence cassettes and vectors containing the same are provided for use in making abundant quantities of recombinant polypeptides of interest. The modified transcriptional control sequences, which include a T5 promoter sequence, are highly stable and can be used in a variety of vectors, such as plasmids.

4. 发明申请

US20050201970A1 Bed sore medicine cream 审中-公开
标题翻译：床胃酸霜
公开(公告)号：US20050201970A1
公开(公告)日：2005-09-15
申请号：US10959630
申请日：2004-10-05
申请人： Mary Hu
发明人： Mary Hu
IPC分类号： A61K36/328 , A61K35/78 , A61K7/06
CPC分类号： A61K36/324 , A61K9/0014 , A61K36/634 , A61K2300/00
摘要： A skin condition relieving medication, which can be directly applied onto a skin condition prone area of a user, is provided for preventing infection and reducing inflammation and swelling, while allowing air to reach the skin condition prone area in order to dry the skin condition and eventually healing the skin condition, wherein the skin condition relieving medication includes a predetermined amount of primary herb mixture including one or more herbs chosen from forsythia, frankincense, myrrh, cuttlefish bone, honeysuckle, turmeric and garden angelica, provided for the treating of the skin conditions, a predetermined amount of catalyst including vitamin E, and a predetermined amount of binding agent, which most suitably is Vaseline containing the primary herb mixture and the catalyst, and binding the primary herb mixture to the skin condition prone area of the user.
摘要翻译：提供可直接施用于使用者的皮肤状况容易区域的皮肤状态缓解药物，用于防止感染并减少炎症和肿胀，同时允许空气到达皮肤状况容易区域以干燥皮肤状况和最终愈合皮肤状况，其中，皮肤状况缓解药物包括预定量的初级草药混合物，包括选自连翘，乳香，没药，乌贼骨，金银花，姜黄和当归的一种或多种草药，用于治疗皮肤条件，预定量的催化剂（包括维生素E）和预定量的粘合剂，其中最合适的是含有初级草本混合物和催化剂的凡士林，并将初级草本混合物结合到使用者的皮肤状况容易区域。

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