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    • 1. 发明授权
    • Palatable suspending vehicle for pharmaceutical ingredients
    • 药物成分的可口悬挂车
    • US08021682B2
    • 2011-09-20
    • US11203520
    • 2005-08-12
    • Joshua RadkeMichael JonesMartin Erickson
    • Joshua RadkeMichael JonesMartin Erickson
    • A61K47/00
    • A61K47/36A61K9/0095A61K9/10A61K31/166A61K31/192A61K31/197A61K31/277A61K31/325A61K47/12A61K47/26A61K47/34
    • The invention relates to a liquid vehicle that can be used to create suspensions and/or solutions of liquid or powdered medications. The vehicle is thixotropic and has improved stability and rheologic characteristics. Vehicles of the invention include an aqueous medium and a suspending agent comprising a polysaccharide having at least 50% glucose repeating saccharide units and at least 90% alpha linkages. The polysaccharide can be a starch, modified starch, or glycogen. The aqueous medium and individual components of the vehicle provide a palatable and easily ingested drug preparation. The invention also provides a vehicle containing an aqueous medium, suspending agent comprising a polysaccharide having at least 50% glucose repeating saccharide units and at least 90% alpha linkages, buffer, and artificial sweetener, the combined suspending vehicle having a pH of about 3 to about 10 and an osmolality of 300 mOmsol or less.
    • 本发明涉及一种液体载体,其可用于产生液体或粉末状药物的悬浮液和/或溶液。 车辆具有触变性,并具有改善的稳定性和流变特性。 本发明的载体包括水性介质和悬浮剂,其包含具有至少50%葡萄糖重复糖单元和至少90%α键的多糖。 多糖可以是淀粉,改性淀粉或糖原。 载体的水性介质和各个组分提供了可口的且容易摄取的药物制剂。 本发明还提供含有水性介质的载体,悬浮剂,其包含具有至少50%葡萄糖重复糖单元和至少90%α键的缓冲剂和人造甜味剂的多糖,所述组合悬浮载体的pH为约3至 约10和重量摩尔渗透压浓度为300mOmsol以下。
    • 5. 发明申请
    • Palatable Suspending Vehicle for Pharmaceutical Ingredients
    • 药物成分的可口悬挂车
    • US20120129951A1
    • 2012-05-24
    • US13207849
    • 2011-08-11
    • Joshua RadkeMichael JonesMartin Erickson
    • Joshua RadkeMichael JonesMartin Erickson
    • A61K47/36A61K47/02
    • A61K47/36A61K9/0095A61K9/10A61K31/166A61K31/192A61K31/197A61K31/277A61K31/325A61K47/12A61K47/26A61K47/34
    • The invention relates to a liquid vehicle that can be used to create suspensions and/or solutions of liquid or powdered medications. The vehicle is thixotropic and has improved stability and rheologic characteristics. Vehicles of the invention include an aqueous medium and a suspending agent comprising a polysaccharide having at least 50% glucose repeating saccharide units and at least 90% alpha linkages. The polysaccharide can be a starch, modified starch, or glycogen. The aqueous medium and individual components of the vehicle provide a palatable and easily ingested drug preparation. The invention also provides a vehicle containing an aqueous medium, suspending agent comprising a polysaccharide having at least 50% glucose repeating saccharide units and at least 90% alpha linkages, buffer, and artificial sweetener, the combined suspending vehicle having a pH of about 3 to about 10 and an osmolality of 300 mOmsol or less.
    • 本发明涉及一种液体载体,其可用于产生液体或粉末状药物的悬浮液和/或溶液。 车辆具有触变性,并具有改善的稳定性和流变特性。 本发明的载体包括水性介质和悬浮剂,其包含具有至少50%葡萄糖重复糖单元和至少90%α键的多糖。 多糖可以是淀粉,改性淀粉或糖原。 载体的水性介质和各个组分提供了可口的且容易摄取的药物制剂。 本发明还提供含有水性介质的载体,悬浮剂,其包含具有至少50%葡萄糖重复糖单元和至少90%α键的缓冲剂和人造甜味剂的多糖,所述组合悬浮载体的pH为约3至 约10和重量摩尔渗透压浓度为300mOmsol以下。
    • 7. 发明申请
    • IMPLEMENTATION OF LIGHT SOURCES WITH ELECTOCAUTERY UNITS
    • 光源采用电子单位实施
    • US20100312241A1
    • 2010-12-09
    • US12769857
    • 2010-04-29
    • Jerry Martin Erickson, JR.
    • Jerry Martin Erickson, JR.
    • A61B18/14
    • A61B18/1402A61B90/30A61B2218/007A61B2218/008
    • An electrocautery unit includes a light source that may be molded to the electrocautery tip during the manufacturing process. The light source may be chosen by the manufacturer that will work with the electrical system used to power the electrocautery. The light source may be monopolor (on demand lighting when the user initiates the electrocautery), bipolar with constant illumination, or separately wired from the electrocautery device and using its own power supply and on and off switch. The shape and/or angle of the light source may be determined by the function desired by the user. A broad angled light source could be used for large areas needing homeostasis. A narrow light could be used to direct illumination directly ahead of the electrocautery unit. The light source may be a light emitting diode (LED), as such a light source may be reusable through gas sterilization or a single use disposable item.
    • 电灼单元包括在制造过程中可以模制到电灼尖端的光源。 光源可以由制造商选择,其将与用于为电灼功率供电的电气系统一起工作。 光源可以是单色的(当用户启动电灼时按要求照明),具有恒定照明的双极,或者与电烙术单独接线并使用其自身的电源和开关。 光源的形状和/或角度可以由用户期望的功能确定。 宽角度光源可用于需要稳态的大面积。 可以使用窄光直接照射直接在电灼单元之前。 光源可以是发光二极管(LED),因为这样的光源可以通过气体灭菌或单次使用的一次性物品可重复使用。
    • 9. 发明申请
    • Palatable suspending vehicle for pharmaceutical ingredients
    • 药物成分的可口悬挂车
    • US20060034873A1
    • 2006-02-16
    • US11203520
    • 2005-08-12
    • Joshua RadkeMichael JonesMartin Erickson
    • Joshua RadkeMichael JonesMartin Erickson
    • A61K9/00
    • A61K47/36A61K9/0095A61K9/10A61K31/166A61K31/192A61K31/197A61K31/277A61K31/325A61K47/12A61K47/26A61K47/34
    • The invention relates to a liquid vehicle that can be used to create suspensions and/or solutions of liquid or powdered medications. The vehicle is thixotropic and has improved stability and rheologic characteristics. Vehicles of the invention include an aqueous medium and a suspending agent comprising a polysaccharide having at least 50% glucose repeating saccharide units and at least 90% beta linkages. The polysaccharide can be a starch, modified starch, or glycogen. The aqueous medium and individual components of the vehicle provide a palatable and easily ingested drug preparation. The invention also provides a vehicle containing an aqueous medium, suspending agent comprising a polysaccharide having at least 50% glucose repeating saccharide units and at least 90% beta linkages, buffer, and artificial sweetener, the combined suspending vehicle having a pH of about 3 to about 10 and an osmolality of 300 mOmsol or less.
    • 本发明涉及一种液体载体,其可用于产生液体或粉末状药物的悬浮液和/或溶液。 车辆具有触变性,并具有改善的稳定性和流变特性。 本发明的载体包括水性介质和悬浮剂,其包含具有至少50%葡萄糖重复糖单元和至少90%β键的多糖。 多糖可以是淀粉,改性淀粉或糖原。 载体的水性介质和各个组分提供了可口的且容易摄取的药物制剂。 本发明还提供含有水性介质的载体,悬浮剂,其包含具有至少50%葡萄糖重复糖单元和至少90%β键的多糖,缓冲剂和人造甜味剂,所述组合悬浮载体的pH为约3至 约10和重量摩尔渗透压浓度为300mOmsol以下。