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1. 发明授权

US06677150B2 Organ preservation apparatus and methods 失效
标题翻译：器官保存仪器及方法
公开(公告)号：US06677150B2
公开(公告)日：2004-01-13
申请号：US09953338
申请日：2001-09-14
申请人： Marlin L. Alford , Robert M. Dowben
发明人： Marlin L. Alford , Robert M. Dowben
IPC分类号： A01N100
CPC分类号： A01N1/0247 , A01N1/02 , A01N1/0273
摘要： This invention is a transportable organ preservation system which substantially increases the time during which the organ can be maintained viable for successful implantation into a human recipient. A chilled oxygenated nutrient solution is pumped through the vascular bed of the organ after excision of the organ from the donor and during transport. The device of the present invention uses flexible permeable tubing to oxygenate the perfusion fluid while the CO2 produced by the organ diffuses out of the perfusion fluid. One pressurized two liter “C” cylinder that contains 255 liters of oxygen at standard temperature and pressure can supply oxygen for up to 34 hours of perfusion time. The device uses a simple electric pump driven by a storage battery to circulate the perfusion fluid through the organ being transported. The vessel containing the organ to be transported is held at 4° C. by coolant blocks.
摘要翻译：本发明是一种可运输的器官保存系统，其大大增加了器官可以维持生存以便成功植入人类接受者的时间。将冷冻的含氧营养液从供体切除并在运输过程中抽出器官的血管床。本发明的装置使用柔性可渗透管来对灌注流体进行氧化，同时由器官产生的CO 2从灌注液中扩散出来。在标准温度和压力下包含255升氧气的一个加压的两升“C”气瓶可以供给氧气长达34小时的灌注时间。该装置使用由蓄电池驱动的简单的电动泵来使灌注流体循环通过被运送的器官。装有运输器官的容器由冷却剂块保持在4℃。

2. 发明授权

US07176015B2 Organ preservation apparatus and methods 有权
标题翻译：器官保存仪器及方法
公开(公告)号：US07176015B2
公开(公告)日：2007-02-13
申请号：US10692394
申请日：2003-10-23
申请人： Marlin L. Alford , Robert M. Dowben
发明人： Marlin L. Alford , Robert M. Dowben
IPC分类号： A01N1/00
CPC分类号： A01N1/0247 , A01N1/02 , A01N1/0273
摘要： This invention is a transportable organ preservation system that substantially increases the time during which the organ can be maintained viable for successful implantation into a human recipient. A chilled oxygenated nutrient solution is pumped through the vascular bed of the organ after excision of the organ from the donor and during transport. The device of the present invention uses flexible permeable tubing to oxygenate the perfusion fluid while the CO2 produced by the organ diffuses out of the perfusion fluid. One pressurized two liter “C” cylinder that contains 255 liters of oxygen at standard temperature and pressure can supply oxygen for up to 34 hours of perfusion time. The device uses a simple electric pump driven by a storage battery to circulate the perfusion fluid through the organ being transported. The vessel containing the organ to be transported is held at 4° C. by coolant blocks.
摘要翻译：本发明是一种可运输的器官保存系统，其大大增加了器官可以维持生存以便成功植入人类接受者的时间。将冷冻的含氧营养液从供体切除并在运输过程中抽出器官的血管床。本发明的装置使用柔性可渗透管将灌注液充氧，同时由器官产生的CO 2从灌注流体中扩散出来。在标准温度和压力下包含255升氧气的一个加压的两升“C”气瓶可以供给氧气长达34小时的灌注时间。该装置使用由蓄电池驱动的简单的电动泵来使灌注流体循环通过被运送的器官。装有运输器官的容器由冷却剂块保持在4℃。

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