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1. 发明授权

US09717494B2 Applier for anchoring a lining to a hollow organ 有权
公开(公告)号：US09717494B2
公开(公告)日：2017-08-01
申请号：US14364452
申请日：2011-12-13
申请人： Jason L. Harris , Alessandro Pastorelli , Michele D'Arcangelo , Mark S. Ortiz , Mark S. Zeiner
发明人： Jason L. Harris , Alessandro Pastorelli , Michele D'Arcangelo , Mark S. Ortiz , Mark S. Zeiner
IPC分类号： A61B17/04 , A61B17/11 , A61B17/30
CPC分类号： A61B17/0491 , A61B17/0469 , A61B2017/1142 , A61B2017/306
摘要： Provided herein are medical apparatuses and methods and more particularly devices and methods for positioning and anchoring a lining to a hollow body organ, such as a stomach, intestine or gastrointestinal tract. For example, in one embodiment, an endoluminal applier includes a fastening assembly configured to receive tissue and lining, a suction device configured to acquire tissue and lining, and a stitching mechanism configured to stitch into the fastening cavity and to apply a running suture to the tissue portion and lining.

2. 发明授权

US08973803B2 Surgical stapling apparatus with control features operable with one hand 有权
标题翻译：具有可手动操作的控制特征的手术吻合装置
公开(公告)号：US08973803B2
公开(公告)日：2015-03-10
申请号：US12878574
申请日：2010-09-09
申请人： Steven G. Hall , Randall J. Tanguay , Jeffrey D. Messerly , Galen C. Robertson , Andrew M. Zwolinski , Frederick E. Shelton, IV , Geoffrey C. Hueil , Mark S. Ortiz , Douglas B. Hoffman , Patrick A. Weizman , Dean B. Bruewer , Gregory B. Blair
发明人： Steven G. Hall , Randall J. Tanguay , Jeffrey D. Messerly , Galen C. Robertson , Andrew M. Zwolinski , Frederick E. Shelton, IV , Geoffrey C. Hueil , Mark S. Ortiz , Douglas B. Hoffman , Patrick A. Weizman , Dean B. Bruewer , Gregory B. Blair
IPC分类号： A61B17/068 , A61B17/072 , A61B19/02 , A61B19/00 , A61B17/00 , A61B17/29 , A61B17/32
CPC分类号： A61B17/105 , A61B17/068 , A61B17/0682 , A61B17/0686 , A61B17/072 , A61B17/07207 , A61B17/115 , A61B50/00 , A61B90/70 , A61B2017/0023 , A61B2017/00367 , A61B2017/00398 , A61B2017/00407 , A61B2017/00473 , A61B2017/00946 , A61B2017/07214 , A61B2017/07271 , A61B2017/07285 , A61B2017/2901 , A61B2017/2905 , A61B2017/2906 , A61B2017/2908 , A61B2017/291 , A61B2017/2923 , A61B2017/2925 , A61B2017/2927 , A61B2017/2929 , A61B2017/320052 , A61B2090/0813
摘要： A surgical stapling apparatus may comprise a handle assembly, a shaft, an end effector, an articulation joint, and an articulation actuator. The handle assembly comprises a first portion and a second portion moveable relative to the first portion. The end effector, connected to the shaft by the articulation joint, is configured to perform an end effector function when the second portion is actuated. The articulation actuator, which is configured to move the end effector relative to the shaft, and the second portion may be moveable in an actuation plane.
摘要翻译：外科缝合装置可以包括手柄组件，轴，端部执行器，关节运动关节和关节运动致动器。手柄组件包括可相对于第一部分移动的第一部分和第二部分。通过铰接接头连接到轴的端部执行器构造成当第二部分被致动时执行端部执行器功能。构造成使端部执行器相对于轴移动的关节运动致动器和第二部分可以在致动平面中移动。

3. 发明授权

US08636751B2 Methods and devices for the rerouting of chyme to induce intestinal brake 有权
标题翻译：用于重新路由食糜诱导肠内制动的方法和装置
公开(公告)号：US08636751B2
公开(公告)日：2014-01-28
申请号：US13104192
申请日：2011-05-10
申请人： Thomas E. Albrecht , Jeffrey L. Aldridge , Sean P. Conlon , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, Jr. , Jason L. Harris , Christopher J. Hess , Kevin L. Houser , Mario Gutierrez , Prasanna Malaviya , Amy L. Marcotte , Jeffrey D. Messerly , Anthony Nguyen , Mark S. Ortiz , Mark D. Overmyer , Alessandro Pastorelli , Galen C. Robertson , Frederick E. Shelton, IV , Michael J. Stokes , Foster B. Stulen , James W. Voegele , Lauren S. Weaner , Tamara S. Vetro Widenhouse , James A. Woodard, Jr. , Mark S. Zeiner
发明人： Thomas E. Albrecht , Jeffrey L. Aldridge , Sean P. Conlon , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, Jr. , Jason L. Harris , Christopher J. Hess , Kevin L. Houser , Mario Gutierrez , Prasanna Malaviya , Amy L. Marcotte , Jeffrey D. Messerly , Anthony Nguyen , Mark S. Ortiz , Mark D. Overmyer , Alessandro Pastorelli , Galen C. Robertson , Frederick E. Shelton, IV , Michael J. Stokes , Foster B. Stulen , James W. Voegele , Lauren S. Weaner , Tamara S. Vetro Widenhouse , James A. Woodard, Jr. , Mark S. Zeiner
IPC分类号： A61B17/10
CPC分类号： A61B17/00234 , A61B5/0031 , A61B5/036 , A61B5/073 , A61B5/076 , A61B5/1107 , A61B5/14532 , A61B5/14539 , A61B5/42 , A61B17/0469 , A61B17/1114 , A61B2017/00876 , A61B2017/1117 , A61B2017/1139 , A61B2560/0219 , A61F2/04 , A61F5/0013 , A61F2002/045
摘要： Methods and devices reroute chyme to induce intestinal brake in order to improve the effectiveness of bariatric surgical procedures and to improve comorbidity resolution. A bowel is manipulated to provide a shortened path for chyme to travel to the ileum. These methods and devices of rerouting chyme to induce intestinal brake may include one or more of a surgical procedure, an implanted device, or a combination of an implant with an improved surgical procedure.
摘要翻译：方法和装置重新路由食糜诱导肠道制动，以提高减肥手术的有效性和改善共病分解。肠道被操纵以提供用于食糜行进到回肠的缩短路径。用于诱导肠内制动器的这些重新路由食糜的方法和装置可以包括外科手术，植入装置或具有改进的外科手术的植入物的组合中的一种或多种。

4. 发明申请

US20120199632A1 ROBOTICALLY-CONTROLLED SURGICAL INSTRUMENT WITH SELECTIVELY ARTICULATABLE END EFFECTOR 有权
标题翻译：具有可选择性终止效应的机器人控制的手术仪器
公开(公告)号：US20120199632A1
公开(公告)日：2012-08-09
申请号：US13369594
申请日：2012-02-09
申请人： James T. Spivey , Mark S. Ortiz , Frederick E. Shelton, IV , Jerome R. Morgan
发明人： James T. Spivey , Mark S. Ortiz , Frederick E. Shelton, IV , Jerome R. Morgan
IPC分类号： A61B17/068 , A61B19/00
CPC分类号： A61B34/30 , A61B1/0052 , A61B1/0058 , A61B17/068 , A61B17/072 , A61B17/07207 , A61B17/115 , A61B17/320016 , A61B17/32053 , A61B34/71 , A61B50/30 , A61B50/36 , A61B90/37 , A61B2017/00057 , A61B2017/00199 , A61B2017/0023 , A61B2017/003 , A61B2017/00309 , A61B2017/00314 , A61B2017/00323 , A61B2017/00327 , A61B2017/00367 , A61B2017/0042 , A61B2017/00473 , A61B2017/00477 , A61B2017/00685 , A61B2017/00734 , A61B2017/0688 , A61B2017/07235 , A61B2017/07242 , A61B2017/07264 , A61B2017/07271 , A61B2017/07278 , A61B2017/2905 , A61B2017/291 , A61B2017/2919 , A61B2017/2923 , A61B2017/2927 , A61B2017/2933 , A61B2017/2937 , A61B2017/2946 , A61B2017/2947 , A61B2017/320052 , A61B2034/306 , A61B2090/0811 , A61B2090/372
摘要： Devices and systems are provided for controlling movement of a working end of a surgical device by means of a robotic system. In one embodiment, systems and devices are provided for moving an end effector on a distal end of a surgical fastening device. Movement can include rotational movement of the end effector about an axis of the shaft, articulation of the end effector relative to the shaft, and actuation of an end effector, e.g., closing, firing, and/or cutting.
摘要翻译：提供了用于通过机器人系统来控制手术装置的工作端的移动的装置和系统。在一个实施例中，系统和装置被提供用于移动外科紧固装置的远端上的末端执行器。运动可以包括端部执行器围绕轴的轴线的旋转运动，端部执行器相对于轴的铰接，以及端部执行器的致动，例如闭合，点火和/或切割。

5. 发明授权

US08226668B2 Tissue apposition method and device involving sheets with integrated tensioning system 失效
标题翻译：组织结合方法和装置涉及具有综合张力系统的片材
公开(公告)号：US08226668B2
公开(公告)日：2012-07-24
申请号：US12113752
申请日：2008-05-01
申请人： Mark S. Zeiner , Michael J. Stokes , Thomas E. Albrecht , Jason L. Harris , Mark S. Ortiz , Lawrence Crainich
发明人： Mark S. Zeiner , Michael J. Stokes , Thomas E. Albrecht , Jason L. Harris , Mark S. Ortiz , Lawrence Crainich
IPC分类号： A61F2/02
CPC分类号： A61F5/0083 , A61B17/0466 , A61B17/0469 , A61B17/0487 , A61B17/064 , A61B17/08 , A61B17/1114 , A61B2017/00818 , A61B2017/0475 , A61B2017/0496 , A61B2017/081 , A61B2017/086 , A61B2017/088 , A61B2017/1142
摘要： A tensioning system for restricting the available volume of a gastric cavity includes a base material that is shaped and dimensioned for surgical attachment to surfaces on or within the body. Multiple tensioning members are incorporated into the base material, each of the tensioning members including a first end and a second end, wherein pulling upon the tensioning member will cause edges of the base material to be drawn together. The method for restricting the available volume of a gastric cavity includes securing edges of a tensioning system to the gastric cavity and drawing the edges of the tissue together to create a fold in the tissue.
摘要翻译：用于限制胃腔的可用体积的张紧系统包括基体材料，该基材的形状和尺寸用于手术附接到身体上或体内的表面。多个张紧构件结合到基底材料中，每个张紧构件包括第一端和第二端，其中拉动张紧构件将使得基底材料的边缘被拉伸在一起。用于限制胃腔的可用体积的方法包括将张紧系统的边缘固定到胃腔并将组织的边缘拉到一起以在组织中产生折痕。

6. 发明申请

US20120165796A1 Pill Catchers 审中-公开
公开(公告)号：US20120165796A1
公开(公告)日：2012-06-28
申请号：US12976726
申请日：2010-12-22
申请人： Mark S. Ortiz , Christopher J. Hess , Jason L. Harris , James W. Voegele , William B. Weisenburgh, II , Mark S. Zeiner , Mark D. Overmyer
发明人： Mark S. Ortiz , Christopher J. Hess , Jason L. Harris , James W. Voegele , William B. Weisenburgh, II , Mark S. Zeiner , Mark D. Overmyer
IPC分类号： A61M31/00
CPC分类号： A61M31/002 , A61B1/041
摘要： Devices and related methods are provided for the controlled delivery of a therapeutic to a targeted location within a body. More particularly, methods and devices are provided for controlling the rate of passage of an orally administered pill through a body, as well as for controlling the delivery of a therapeutic within the pill at a specific location within the body. Various types of devices, generally referred to herein as “catchers,” are provided that can actively catch a pill as it passes through a body. The catcher can hold the pill at a specific location within the body until a predetermined event occurs, such as partial or complete administration of a therapeutic within the pill. The catcher can then release the pill upon command and/or upon the occurrence of the predetermined event to allow the pill to pass out of the body. In other embodiments, various types of pills are provided that can actively engage a catcher and remain engaged with the catcher until a predetermined event occurs.

7. 发明授权

US08114345B2 System and method of sterilizing an implantable medical device 有权
标题翻译：对可植入医疗器械进行消毒的系统和方法
公开(公告)号：US08114345B2
公开(公告)日：2012-02-14
申请号：US12028344
申请日：2008-02-08
申请人： Daniel F. Dlugos, Jr. , Mark S. Ortiz , David N. Plescia , Mark Leuenberger
发明人： Daniel F. Dlugos, Jr. , Mark S. Ortiz , David N. Plescia , Mark Leuenberger
IPC分类号： A61L2/00 , A61B17/08 , A61N1/00
CPC分类号： A61L2/081 , A61F5/005 , A61L2/082 , A61L2/087 , A61L2202/24
摘要： An implantable system having internal circuitry configured to withstand a pre-determined amount of sterilization radiation is provided. In general, the system includes an internal control module in electrical communication with an implantable medical device. The internal control module can include a circuit board configured to withstand radiation and/or any number of integrated circuits (e.g., application specific integrated circuits) wherein the circuits or at least some portion thereof are fabricated so as to withstand some amount of radiation. For example, some portion of the circuitry can be fabricated utilizing radiation compliant material(s), silicon-on-insulator technology, and/or gallium arsenide technology. Additionally, the circuitry can include various components which are inherently resistant to such radiation (e.g., components fabricated utilizing magnetic field based technology, surface acoustical wave devices, etc.). A method of sterilizing an implantable medical device via radiation is also provided.
摘要翻译：提供了具有内部电路的可植入系统，该内部电路被配置为经受预定量的灭菌辐射。通常，该系统包括与可植入医疗装置电通信的内部控制模块。内部控制模块可以包括被配置为承受辐射和/或任何数量的集成电路（例如，专用集成电路）的电路板，其中制造电路或其至少一部分以承受一定量的辐射。例如，电路的一些部分可以使用辐射兼容材料，绝缘体上硅技术和/或砷化镓技术来制造。此外，电路可以包括固有地抵抗这种辐射的各种部件（例如，使用基于磁场的技术制造的部件，表面声波装置等）。还提供了通过辐射对可植入医疗装置进行消毒的方法。

8. 发明授权

US08096459B2 Surgical stapler with an end effector support 有权
标题翻译：具有端部执行器支撑的手术吻合器
公开(公告)号：US08096459B2
公开(公告)日：2012-01-17
申请号：US11163243
申请日：2005-10-11
申请人： Mark S. Ortiz , Michael Stokes
发明人： Mark S. Ortiz , Michael Stokes
IPC分类号： A61B17/068
CPC分类号： A61B17/072 , A61B17/07207 , A61B2017/2926 , A61B2017/2933 , A61B2017/2939 , A61B2017/2941
摘要： A surgical stapler is provided having a cartridge arm for holding staples, an anvil pivotally connected thereto to deform fired staples from the cartridge arm, and a support for substantially preventing anvil deflection during staple firing to help insure proper staple formation. Some supports allow pivoting between the anvil and cartridge arm when in a first position, but prevent or hinder the pivoting action when in a second position. Supports can also be adapted to contact the anvil at a distal position relative to the pivot point between the anvil and cartridge arm. Exemplary structures of supports embodied as one or more links or as a sleeve are described. Methods of use are also discussed.
摘要翻译：提供了一种外科缝合器，其具有用于夹持钉的钉仓臂，枢转地连接到其上的砧座，以使钉臂上的钉钉变形，以及用于在短纤维烧制期间基本上防止砧座偏转的支撑件，以帮助确保适当的缝合钉形成。一些支撑件允许在处于第一位置时在砧座和钉仓臂之间枢转，但是当处于第二位置时防止或阻碍枢转动作。支撑件还可以适于在相对于砧座和钉仓臂之间的枢转点的远侧位置处接触砧座。描述了作为一个或多个链路或套筒体现的支持体的示例性结构。还讨论了使用方法。

9. 发明申请

US20110295337A1 Systems and Methods For Regulating Metabolic Hormone Producing Tissue 审中-公开
标题翻译：用于调节代谢激素生产组织的系统和方法
公开(公告)号：US20110295337A1
公开(公告)日：2011-12-01
申请号：US13105262
申请日：2011-05-11
申请人： Thomas E. Albrecht , Jeffrey L. Aldridge , Edward G. Chekan , Sean P. Conlon , Michael S. Cropper , Daniel F. Dlugos, JR. , Jason L. Harris , Christopher J. Hess , Kevin L. Houser , John V. Hunt , Gary L. Long , Prasanna Malaviya , Amy L. Marcotte , Rudolph H. Nobis , Mark S. Ortiz , Mark D. Overmyer , Alessandro Pastorelli , David N. Plescia , Galen C. Robertson , Randy J. Seeley , Frederick E. Shelton, IV , Michael J. Stokes , Foster B. Stulen , Richard W. Timm , James W. Voegele , William B. Weisenburgh, II , James A. Woodard, JR. , David C. Yates , Andrew M. Zwolinski
发明人： Thomas E. Albrecht , Jeffrey L. Aldridge , Edward G. Chekan , Sean P. Conlon , Michael S. Cropper , Daniel F. Dlugos, JR. , Jason L. Harris , Christopher J. Hess , Kevin L. Houser , John V. Hunt , Gary L. Long , Prasanna Malaviya , Amy L. Marcotte , Rudolph H. Nobis , Mark S. Ortiz , Mark D. Overmyer , Alessandro Pastorelli , David N. Plescia , Galen C. Robertson , Randy J. Seeley , Frederick E. Shelton, IV , Michael J. Stokes , Foster B. Stulen , Richard W. Timm , James W. Voegele , William B. Weisenburgh, II , James A. Woodard, JR. , David C. Yates , Andrew M. Zwolinski
IPC分类号： A61N1/36
CPC分类号： A61N1/00 , A61F5/0026 , A61N1/0509 , A61N1/327 , A61N1/36007
摘要： A method for regulating hormone production comprises placing at least one electrode in a gastrointestinal tract of a patient and recording an electrical signal during a preselected event produced by the gastrointestinal tract. The method further involves the steps of storing the electrical signal, and playing back the electrical signal by activating the electrode during the absence of the preselected event.
摘要翻译：用于调节激素产生的方法包括将至少一个电极放置在患者的胃肠道中，并在由胃肠道产生的预选事件期间记录电信号。该方法还包括存储电信号的步骤，以及在没有预选事件期间激活电极来播放电信号。

10. 发明申请

US20110295286A1 METHODS AND DEVICES FOR REGULATING THE ACTIVATION OF GHRELIN HORMONES WITHIN A STOMACH 有权
标题翻译：调节GHRELIN HORMONES在STOMACH中激活的方法和装置
公开(公告)号：US20110295286A1
公开(公告)日：2011-12-01
申请号：US13105006
申请日：2011-05-11
申请人： Jason L. Harris , Mark S. Ortiz , Mark D. Overmyer , Michael J. Stokes
发明人： Jason L. Harris , Mark S. Ortiz , Mark D. Overmyer , Michael J. Stokes
IPC分类号： A61B17/11
CPC分类号： A61F5/0076 , A61B2017/0404 , A61F5/0083
摘要： Methods and devices regulate the activation of ghrelin hormones within a stomach in order to treat weight disorders, to promote learning and memory functions, to treat stress-induced depression, and to control sleep duration. In one embodiment, a method for regulating activation of ghrelin hormones within a stomach comprises a means for isolating non-activated ghrelin hormones from food content and dietary lipids within the stomach. These means for isolating may take any number of forms and may comprise one or more of a surgical procedure, an implanted device, or an ingestible substance.
摘要翻译：方法和装置调节胃内生长素释放激素的激活，以治疗体重紊乱，促进学习和记忆功能，治疗压力诱导的抑郁症和控制睡眠持续时间。在一个实施方案中，用于调节胃内生长素释放激素激活的方法包括从胃中的食物含量和膳食脂质中分离未活化的生长素释放肽激素的方法。这些用于隔离的装置可以采取任何数量的形式，并且可以包括外科手术，植入装置或可摄取物质中的一种或多种。

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