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    • 2. 发明授权
    • Bacteriorhodopsin-based sensors
    • 基于细菌视紫红质的传感器
    • US08551407B2
    • 2013-10-08
    • US12325718
    • 2008-12-01
    • Craig FriedrichDonald LuekingMark Griep
    • Craig FriedrichDonald LuekingMark Griep
    • G01N21/01
    • G01N21/6454G01N21/6428G01N33/54373
    • A sensor comprising a membrane containing bacteriorhodopsin. In one embodiment, the sensor comprises a layer of purple membrane between a first and a second electrode, wherein the electrodes are connected to a circuit such that a signal is produced when a charge is transferred across the membrane. In another embodiment, the sensor comprises a field effect transistor with a layer of purple membrane deposited on the gate. The layer of purple membrane may be further functionalized by adding fluorophores to the layer of purple membrane. The fluorophores may be deposited adjacent to the layer of purple membrane, or the fluorophores may be attached to the layer of purple membrane with linkages. The fluorophores or linkages between the fluorophores and the purple membrane may be functionalized with receptors to produce sensors for targeted chemical or biological species.
    • 包含含有细菌视紫红质的膜的传感器。 在一个实施例中,传感器包括在第一和第二电极之间的紫色膜层,其中电极连接到电路,使得当电荷跨越膜转移时产生信号。 在另一个实施例中,传感器包括具有沉积在栅极上的紫膜层的场效应晶体管。 可以通过向紫色膜层中加入荧光团而使紫色膜层进一步官能化。 荧光团可以沉积在紫膜附近,或者荧光团可以连接到紫色膜层上。 荧光团或荧光团与紫色膜之间的连接可用受体官能化,以产生靶向化学或生物物种的传感器。
    • 3. 发明申请
    • BACTERIORHODOPSIN-BASED SENSORS
    • 基于传感器的传感器
    • US20090142852A1
    • 2009-06-04
    • US12325718
    • 2008-12-01
    • Craig FriedrichDonald LuekingMark Griep
    • Craig FriedrichDonald LuekingMark Griep
    • G01N21/64
    • G01N21/6454G01N21/6428G01N33/54373
    • A sensor comprising a membrane containing bacteriorhodopsin. In one embodiment, the sensor comprises a layer of purple membrane between a first and a second electrode, wherein the electrodes are connected to a circuit such that a signal is produced when a charge is transferred across the membrane. In another embodiment, the sensor comprises a field effect transistor with a layer of purple membrane deposited on the gate. The layer of purple membrane may be further functionalized by adding fluorophores to the layer of purple membrane. The fluorophores may be deposited adjacent to the layer of purple membrane, or the fluorophores may be attached to the layer of purple membrane with linkages. The fluorophores or linkages between the fluorophores and the purple membrane may be functionalized with receptors to produce sensors for targeted chemical or biological species.
    • 包含含有细菌视紫红质的膜的传感器。 在一个实施例中,传感器包括在第一和第二电极之间的紫色膜层,其中电极连接到电路,使得当电荷跨越膜转移时产生信号。 在另一个实施例中,传感器包括具有沉积在栅极上的紫膜层的场效应晶体管。 可以通过向紫色膜层中加入荧光团而使紫色膜层进一步官能化。 荧光团可以沉积在紫膜附近,或者荧光团可以连接到紫色膜层上。 荧光团或荧光团与紫色膜之间的连接可用受体官能化,以产生靶向化学或生物物种的传感器。