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1. 发明申请

US20130158625A1 Respiratory Rectification 有权
标题翻译：呼吸整形
公开(公告)号：US20130158625A1
公开(公告)日：2013-06-20
申请号：US13529770
申请日：2012-06-21
申请人： Mark Gelfand , Kristofer J. James , Randy W. Westlund , Antonis Panteleon , Todd P. Goblish , Mark C. Lynn
发明人： Mark Gelfand , Kristofer J. James , Randy W. Westlund , Antonis Panteleon , Todd P. Goblish , Mark C. Lynn
IPC分类号： A61N1/36
CPC分类号： A61N1/3601 , A61N1/3611 , A61N1/36171
摘要： A means for treating breathing disorders by stimulating respiratory muscles or nerves to entrain respiratory systems while leaving respiratory drive intact. Embodiments of the invention employ frequency analysis to determine if appropriate stimulation energy is being applied.
摘要翻译：一种通过刺激呼吸肌或神经夹带呼吸系统同时使呼吸驱动完好无损来治疗呼吸障碍的手段。本发明的实施例采用频率分析来确定是否正在施加适当的刺激能量。

2. 发明申请

US20090306753A1 LEAD ASSEMBLY AND RELATED METHODS 有权
标题翻译：铅装配及相关方法
公开(公告)号：US20090306753A1
公开(公告)日：2009-12-10
申请号：US12437470
申请日：2009-05-07
申请人： Mark C. Lynn , Luis J. Morales Cardona , Peter Hall
发明人： Mark C. Lynn , Luis J. Morales Cardona , Peter Hall
IPC分类号： A61N1/05 , H01R43/00
CPC分类号： A61N1/0563 , A61N2001/0578 , Y10T29/49174 , Y10T29/49224
摘要： Defibrillator lead designs and methods for manufacturing a lead having a fibrosis-limiting material covering, a shocking coil electrode, and an implantable lead body are disclosed herein. The shocking coil electrode includes at least one laser welded portion.
摘要翻译：本文公开了除颤器引线设计和用于制造具有纤维化限制材料覆盖物的引线的方法，冲击线圈电极和可植入引线体。冲击线圈电极包括至少一个激光焊接部分。

3. 发明申请

US20090287286A1 LEAD ASSEMBLY AND RELATED METHODS 有权
标题翻译：铅装配及相关方法
公开(公告)号：US20090287286A1
公开(公告)日：2009-11-19
申请号：US12437504
申请日：2009-05-07
申请人： Mark C. Lynn
发明人： Mark C. Lynn
IPC分类号： A61N1/05
CPC分类号： A61N1/0563
摘要： Defibrillator lead designs and methods for manufacturing a lead including attachment between a fibrosis-limiting material covering, a shocking coil electrode, and an implantable lead body are disclosed herein. The shocking coil electrode includes at least one treated portion. The fibrosis limiting material includes a selectively modified portion that is disposed over the at least one treated portion.
摘要翻译：本文公开了除颤器引线设计和用于制造包括纤维化限制材料覆盖物，冲击性线圈电极和可植入引线体之间的连接的引线的方法。冲击线圈电极包括至少一个处理部分。纤维化限制材料包括设置在至少一个处理部分上的选择性改性部分。

4. 发明授权

US09999768B2 Respiratory rectification 有权
公开(公告)号：US09999768B2
公开(公告)日：2018-06-19
申请号：US13529770
申请日：2012-06-21
申请人： Mark Gelfand , Kristofer J. James , Randy W. Westlund , Antonis Panteleon , Todd P. Goblish , Mark C. Lynn
发明人： Mark Gelfand , Kristofer J. James , Randy W. Westlund , Antonis Panteleon , Todd P. Goblish , Mark C. Lynn
IPC分类号： A61N1/36
CPC分类号： A61N1/3601 , A61N1/3611 , A61N1/36171
摘要： A means for treating breathing disorders by stimulating respiratory muscles or nerves to entrain respiratory systems while leaving respiratory drive intact. Embodiments of the invention employ frequency analysis to determine if appropriate stimulation energy is being applied.

5. 发明申请

US20120209284A1 Medical Lead and Implantation 有权
标题翻译：医疗铅和植入
公开(公告)号：US20120209284A1
公开(公告)日：2012-08-16
申请号：US13049520
申请日：2011-03-16
申请人： Randy W. Westlund , Mark C. Lynn
发明人： Randy W. Westlund , Mark C. Lynn
IPC分类号： A61N1/05 , A61B19/00
CPC分类号： A61N1/056 , A61M25/0041 , A61M25/0054 , A61M25/0068 , A61M25/0662 , A61M25/0668 , A61M29/00 , A61M2025/0081
摘要： A lead for navigating small vessels and a catheter system for implantation of leads into small vessels. Veins that return blood to the heart against the force of gravity often have valves in them to prevent backflow of deoxygenated blood. Leads and catheter systems in accordance with embodiments of the invention allow cannulation and lead implantation in small, tortuous, obstructed, and difficult to access veins enabling a range of stimulation and sensing applications.
摘要翻译：用于导航小容器的导线和用于将引线植入小容器的导管系统。血液通过重力往血液中返回心脏通常会有阀门，以防止脱氧血液回流。根据本发明的实施例的引线和导管系统允许插管和引线植入在小的，曲折的，阻塞的和难以访问的静脉中，从而实现一系列的刺激和感测应用。

6. 发明授权

US08233987B2 Respiratory rectification 有权
标题翻译：呼吸整治
公开(公告)号：US08233987B2
公开(公告)日：2012-07-31
申请号：US12557084
申请日：2009-09-10
申请人： Mark Gelfand , Kristofer J. James , Randy W. Westlund , Antonis Panteleon , Todd P. Goblish , Mark C. Lynn
发明人： Mark Gelfand , Kristofer J. James , Randy W. Westlund , Antonis Panteleon , Todd P. Goblish , Mark C. Lynn
IPC分类号： A61N1/36
CPC分类号： A61N1/3601 , A61N1/3611 , A61N1/36171
摘要： A means for treating breathing disorders by stimulating respiratory muscles or nerves to entrain respiratory systems while leaving respiratory drive intact. Embodiments of the invention employ frequency analysis to determine if appropriate stimulation energy is being applied.
摘要翻译：一种通过刺激呼吸肌或神经夹带呼吸系统同时使呼吸驱动完好无损来治疗呼吸障碍的手段。本发明的实施例采用频率分析来确定是否正在施加适当的刺激能量。

7. 发明授权

US09468755B2 Medical lead with preformed bias 有权
标题翻译：医用铅带有预制偏差
公开(公告)号：US09468755B2
公开(公告)日：2016-10-18
申请号：US12571103
申请日：2009-09-30
申请人： Randy W. Westlund , Mark C. Lynn
发明人： Randy W. Westlund , Mark C. Lynn
IPC分类号： A61N1/05
CPC分类号： A61N1/0558 , A61N1/056 , A61N1/057
摘要： A medical electrical lead and methods of implanting medical electrical leads in lumens. Leads in accordance with the invention employ preformed biases to stabilize the lead within a lumen and to orient electrodes in a preferred orientation.
摘要翻译：一种医用电导线，以及以流明植入医用电线的方法。根据本发明的引线采用预先形成的偏压，以使引线在管腔内稳定并且以优选取向定向电极。

8. 发明授权

US08401669B2 Lead assembly and related methods 有权
标题翻译：铅装配及相关方法
公开(公告)号：US08401669B2
公开(公告)日：2013-03-19
申请号：US12437504
申请日：2009-05-07
申请人： Mark C Lynn
发明人： Mark C Lynn
IPC分类号： A61N1/00
CPC分类号： A61N1/0563
摘要： Defibrillator lead designs and methods for manufacturing a lead including attachment between a fibrosis-limiting material covering, a shocking coil electrode, and an implantable lead body are disclosed herein. The shocking coil electrode includes at least one treated portion. The fibrosis limiting material includes a selectively modified portion that is disposed over the at least one treated portion.
摘要翻译：本文公开了除颤器引线设计和用于制造包括纤维化限制材料覆盖物，冲击性线圈电极和可植入引线体之间的连接的引线的方法。冲击线圈电极包括至少一个处理部分。纤维化限制材料包括设置在至少一个处理部分上的选择性改性部分。

9. 发明申请

US20100125321A1 EPTFE FILL OF COIL FILAR GAPS 审中-公开
标题翻译： EPTFE填充线圈盖
公开(公告)号：US20100125321A1
公开(公告)日：2010-05-20
申请号：US12576706
申请日：2009-10-09
申请人： Mark C. LYNN , Shrojalkumar Desai
发明人： Mark C. LYNN , Shrojalkumar Desai
IPC分类号： A61N1/05 , H01B13/00
CPC分类号： A61N1/0563 , A61N1/056 , Y10T29/49117
摘要： A medical electrical lead includes a coiled electrode. In one example, the coiled electrode includes two conductive filars wound in parallel to define a plurality of turns and a gap between each turn. A polymeric filling is disposed in at least some of the gaps existing between each of the turns. The polymeric filling can include multiple layers of a thin polymeric film or a non-conductive, polymeric filar. The coiled electrode also includes a polymeric covering disposed over the outer surface of the electrode. The polymeric covering is bonded to the polymeric filling disposed in the gaps. The polymeric film includes a non-expanded polymer and the polymeric cover includes an expanded polymer. In some examples the non-expanded polymer is polytetrafluoroethylene (PTFE) and the non-expanded polymer is expanded polytetrafluoroethylene (ePTFE).
摘要翻译：医用电线包括线圈电极。在一个示例中，线圈电极包括平行缠绕的两个导电丝，以限定多个匝数和每匝之间的间隙。聚合物填充物设置在每个匝之间存在的至少一些间隙中。聚合物填充物可以包括多层薄聚合物膜或非导电聚合物丝。线圈电极还包括设置在电极的外表面上的聚合物覆盖物。聚合物覆盖物结合到设置在间隙中的聚合物填充物。聚合物膜包括非发泡聚合物，聚合物覆盖物包括发泡聚合物。在一些实例中，非发泡聚合物是聚四氟乙烯（PTFE），非发泡聚合物是膨胀聚四氟乙烯（ePTFE）。

10. 发明授权

US09744349B2 Medical lead and implantation 有权
公开(公告)号：US09744349B2
公开(公告)日：2017-08-29
申请号：US13049520
申请日：2011-03-16
申请人： Randy W. Westlund , Mark C. Lynn
发明人： Randy W. Westlund , Mark C. Lynn
IPC分类号： A61B19/00 , A61N1/05 , A61M25/00 , A61M25/06 , A61M29/00
CPC分类号： A61N1/056 , A61M25/0041 , A61M25/0054 , A61M25/0068 , A61M25/0662 , A61M25/0668 , A61M29/00 , A61M2025/0081
摘要： A lead for navigating small vessels and a catheter system for implantation of leads into small vessels. Veins that return blood to the heart against the force of gravity often have valves in them to prevent backflow of deoxygenated blood. Leads and catheter systems in accordance with embodiments of the invention allow cannulation and lead implantation in small, tortuous, obstructed, and difficult to access veins enabling a range of stimulation and sensing applications.

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