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1. 发明授权

US07034116B2 Methyltransferase gene and enzyme 有权
公开(公告)号：US07034116B2
公开(公告)日：2006-04-25
申请号：US10273769
申请日：2002-10-18
申请人： Michael P. Kladde , Robert T. Simpson , Mai Xu
发明人： Michael P. Kladde , Robert T. Simpson , Mai Xu
IPC分类号： C07K1/00 , C07H21/02 , C07H21/04 , A01N63/00
CPC分类号： C12N9/1007
摘要： A novel cytosine-5 DNA methyltransferase, isolated from Chlorella virus NYs-1, and its encoded enzyme are disclosed. The methyltransferase recognizes a GpC dinucleotide in DNA. Methods of using the novel methyltransferase in high resolution chromatin mapping and related techniques are also disclosed.

2. 发明授权

US06492168B1 Methyltransferase gene and enzyme 有权
标题翻译：甲基转移酶基因和酶
公开(公告)号：US06492168B1
公开(公告)日：2002-12-10
申请号：US09296840
申请日：1999-04-22
申请人： Michael P. Kladde , Robert T. Simpson , Mai Xu
发明人： Michael P. Kladde , Robert T. Simpson , Mai Xu
IPC分类号： C12N500
CPC分类号： C12N9/1007
摘要： A novel cytosine-5 DNA methyltransferase, isolated from Chlorella virus NYs-1, and its encoded enzyme are disclosed. The methyltransferase recognizes a GpC dinucleotide in DNA. Methods of using the novel methyltransferase in high resolution chromatin mapping and related techniques are also disclosed.
摘要翻译：公开了从小球藻病毒NYs-1分离的新型胞嘧啶-5 DNA甲基转移酶及其编码的酶。甲基转移酶识别DNA中的GpC二核苷酸。还公开了在高分辨率染色质定位和相关技术中使用新型甲基转移酶的方法。

3. 发明申请

US20230110470A1 Sorbent-based oxygen separation 有权
公开(公告)号：US20230110470A1
公开(公告)日：2023-04-13
申请号：US17901537
申请日：2022-09-01
申请人： Ellen B. Stechel , Ivan Ermanoski , Shuguang Deng , Mai Xu
发明人： Ellen B. Stechel , Ivan Ermanoski , Shuguang Deng , Mai Xu
IPC分类号： B01D53/04 , B01J20/04 , B01J20/02
摘要： Separating oxygen from a gas includes contacting an oxygen-selective sorbent with a gas stream, adsorbing oxygen in the gas stream with the sorbent, heating the sorbent to greater than 400° C., and desorbing a majority of the oxygen. The sorbent is selective for oxygen, and adsorbing occurs at a temperature between 275-325° C. An oxygen separation system includes a sorption bed, a heater configured to heat the sorption bed, an oxygen analyzer, a first conduit configured provide an input gas to the sorption bed, a second conduit configured to provide processed input gas from the sorption bed to the oxygen analyzer, a third conduit configured to provide a purge gas to the sorption bed, and a fourth conduit configured to provide processed purge gas to the oxygen analyzer. The first and third conduits are configured to flow the input gas and the purge gas flow in opposite directions through the sorption bed.

4. 发明申请

US20050136434A1 Isolated heat-inducible cell surface protein and hyperthermia-based tumor immunotargeting therapy 审中-公开
标题翻译：分离的热诱导细胞表面蛋白和基于热疗的肿瘤免疫靶向治疗
公开(公告)号：US20050136434A1
公开(公告)日：2005-06-23
申请号：US10916923
申请日：2004-08-12
申请人： Mai Xu
发明人： Mai Xu
IPC分类号： C07K14/705 , C07K16/30 , G09G3/34 , G09G3/36 , H04M1/22 , H04M1/73 , C12Q1/68 , C07H21/04 , G01N33/574
CPC分类号： C07K16/30 , C07K14/705
摘要： An isolated, purified and characterized gene comprising a polynucleotide having a sequence shown in Seq. Id. No. 1. An isolated, purified and characterized protein comprising a polypeptide having a sequence shown in Seq. Id. Nos. 2 & 4-12, respectively. In an aspect, a method of activating a gene or inducing the gene encoded protein comprises intentionally applying finite heat for a time and in an amount effective to living cells, tissues, organs or a whole body to cause and thereby causing activation of a gene comprising a polynucleotide having a sequence shown in Seq. Id. No. 1 and production of an encoded protein comprising a polypeptide having a sequence shown in Seq. Id. Nos. 2 & 4-12, respectively. In an aspect, a method of stress including hyperthermia-based tumor immunotargeting therapy for the treatment of neoplasm and pre-cancerous lesions.
摘要翻译：一种分离，纯化和表征的基因，其包含具有Seq。 ID。一种分离的，纯化和表征的蛋白质，其包含具有Seq。 ID。第2和4-12号。一方面，激活基因或诱导基因编码的蛋白质的方法包括有意地施加有限热量一段时间并且以有效量的活细胞，组织，器官或全身的量来引起和从而引起基因的激活，所述基因包含具有Seq。 ID。编码蛋白质的制备，其包含具有Seq。所示序列的多肽。 ID。第2和4-12号。一方面，应用包括基于热疗的肿瘤免疫靶向治疗用于治疗肿瘤和癌前病变的应激方法。

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