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1. 发明授权

US06231841B1 Antiperspirant compositions 失效
标题翻译：止汗组合物
公开(公告)号：US06231841B1
公开(公告)日：2001-05-15
申请号：US09547625
申请日：2000-04-12
申请人： Kevin Ronald Franklin , Lynda Grainger , Adam Jan Kowalski
发明人： Kevin Ronald Franklin , Lynda Grainger , Adam Jan Kowalski
IPC分类号： A61K732
CPC分类号： A61Q15/00 , A61K8/26 , A61K8/28 , A61K8/44 , A61K8/585 , A61K8/63
摘要： Antiperspirant compositions herein comprise an antiperspirant active, a carrier and a structurant for the carrier which comprises an effective concentration of a combination of at least one sterol and at least one sterol ester, to form a solid or a soft solid. The compositions can be anhydrous and in the form of a suspension of antiperspirant active, or can comprise aqueous emulsions. A particularly suitable sterol comprises &bgr; sitosterol and a particularly preferred sterol ester comprises oryzanol. Preferably the mole ratio of sterol to sterol ester is in the range of 3:1 to 1:2.
摘要翻译：本发明的止汗剂组合物包含止汗剂活性物质，载体和用于载体的结构剂，其包含有效浓度的至少一种甾醇和至少一种甾醇酯的组合以形成固体或软固体。组合物可以是无水的，并且是止汗剂活性物的悬浮液的形式，或者可以包含水性乳液。特别合适的固醇包含β-谷甾醇，特别优选的甾醇酯包含谷维素。优选地，甾醇与甾醇酯的摩尔比在3:1至1:2的范围内。

2. 发明授权

US06737048B2 Antiperspirant formulations 有权
标题翻译：止汗剂配方
公开(公告)号：US06737048B2
公开(公告)日：2004-05-18
申请号：US10096808
申请日：2002-03-13
申请人： Sven Jorg Willi Max Abend , Jean-Philippe Andre Roger Courtois , Martin Peter Cropper , Neil Robert Fletcher , Lynda Grainger , Angela Mary Murphy
发明人： Sven Jorg Willi Max Abend , Jean-Philippe Andre Roger Courtois , Martin Peter Cropper , Neil Robert Fletcher , Lynda Grainger , Angela Mary Murphy
IPC分类号： A61K732
CPC分类号： A61K8/894 , A61K8/042 , A61K8/06 , A61K8/064 , A61K8/26 , A61K8/28 , A61K8/34 , A61K8/60 , A61Q15/00 , Y10S514/937 , Y10S514/938
摘要： Structured antiperspirant emulsion formulations for topical application to human skin in a cosmetic method for controlling sweat and body odor generation can suffer from problems of impaired sensory properties and impaired efficacy (sweat reduction), which are ameliorated or overcome in structured antiperspirant emulsions in which (%s by weight of the emulsion) i) the hydrophilic phase comprises 25 to 55%; ii) the hydrophilic phase contains 0 to 15% polyhydric alcohol; iii) the emulsifier comprises an alkyl dimethicone copolyol; iv) the weight ratio of the hydrophilic phase to the emulsifier is selected in the range of at least 60:1 v) the structurant comprises an acylated sugar and vi) the water-immiscible oil and the structurant are present in a weight ratio of 1.5:1 to 8.5:1.
摘要翻译：在用于控制汗水和体臭产生的美容方法中用于局部施用于人皮肤的结构化止汗剂乳液制剂可能遭受在结构化止汗剂乳液中改善或克服的功效受损（汗水减少）的受损性问题，其中（％）i）亲水相包含25至55％; ii）亲水相含有0至15％的多元醇; iii）乳化剂包含烷基聚二甲基硅氧烷共聚多元醇; iv）亲水相的重量比在至少60:1v范围内选择乳化剂）结构剂包含酰化糖，和）水不混溶油和结构剂以1.5:1至8.5:1的重量比存在。

3. 发明授权

US06241976B1 Antiperspirant compositions 有权
标题翻译：止汗组合物
公开(公告)号：US06241976B1
公开(公告)日：2001-06-05
申请号：US09547445
申请日：2000-04-12
申请人： Isabelle Claire Esser , Kevin Ronald Franklin , Lynda Grainger , Adam Jan Kowalski , Kathryn Elizabeth Rowe
发明人： Isabelle Claire Esser , Kevin Ronald Franklin , Lynda Grainger , Adam Jan Kowalski , Kathryn Elizabeth Rowe
IPC分类号： A61K732
CPC分类号： A61Q15/00 , A61K8/042 , A61K8/06
摘要： An antiperspirant composition is a structured emulsion of a continuous phase containing water-immiscible liquid carrier plus a structurant, and a disperse phase which is a solution of antiperspirant active in water or a mixture of water and water-soluble solvent. The structurant is a fully or partially esterified saccharide. The compositions give low visible residue when applied to skin or to clothing.
摘要翻译：止汗组合物是含有水不混溶性液体载体加结构剂的连续相的结构化乳液，以及作为活性成分为止汗剂的水或水和水溶性溶剂的混合物的分散相。结构剂是完全或部分酯化的糖。当施用于皮肤或衣服时，组合物给出低可见残留物。

4. 发明授权

US5939056A Underarm composition 失效
标题翻译：腋下组成
公开(公告)号：US5939056A
公开(公告)日：1999-08-17
申请号：US923598
申请日：1997-09-04
申请人： Neil Robert Fletcher , Lynda Grainger , Desmond Bernard Hagan , Nina Maria Lewkowicz , Ian Robert McMillan , John Harold Stewart Rennie
发明人： Neil Robert Fletcher , Lynda Grainger , Desmond Bernard Hagan , Nina Maria Lewkowicz , Ian Robert McMillan , John Harold Stewart Rennie
IPC分类号： A61K8/25 , A61K8/28 , A61K8/58 , A61K8/81 , A61K8/891 , A61K33/04 , A61Q15/00 , A61K7/32 , A61K7/00
CPC分类号： A61Q15/00 , A61K8/25 , A61K8/28 , A61K8/585 , A61K8/8111 , A61K8/891
摘要： A substantially anhydrous underarm cream composition suitable for topical application to the human skin, comprising an antiperspirant and/or deodorant agent, a carrier, a silica structurant and an alkyl methicone wax having the general formula:(CH.sub.3).sub.3 Si--�O--Si(R)(CH.sub.3)!.sub.x --O--Si(CH.sub.3).sub.3wherein R is a branched or unbranched alkyl group containing from 12 to 26 carbon atoms, the ratio of branched to unbranched alkyl groups is approximately from 1:5 to 1:2 and x ranges from 30 to 150.
摘要翻译：适用于局部施用于人体皮肤的基本上无水的腋下乳膏组合物，其包含止汗剂和/或除臭剂，载体，二氧化硅结构剂和具有以下通式的烷基甲基硅油：（CH 3）3 Si- [O-Si（ R）（CH3）] xO-Si（CH3）3，其中R是含有12至26个碳原子的支链或非支链烷基，支链与非支链烷基的比例约为1:5至1:2，x范围从30到150。

5. 发明授权

US06680048B2 Esters 有权
标题翻译：酯类
公开(公告)号：US06680048B2
公开(公告)日：2004-01-20
申请号：US09978954
申请日：2001-10-17
申请人： Lynda Grainger , Kathryn Elizabeth Gransden , Andrew Hopkinson , Adam Jan Kowalski , Nicholas Webb , Michael Stephen White
发明人： Lynda Grainger , Kathryn Elizabeth Gransden , Andrew Hopkinson , Adam Jan Kowalski , Nicholas Webb , Michael Stephen White
IPC分类号： A61K732
CPC分类号： A61K8/0229 , A61K8/06 , A61K8/064 , A61K8/73 , A61Q15/00 , A61Q19/00
摘要： Cellobiose esters and particularly &agr; cellobiose octanonanoate has been found able to structure water-immiscible liquids well, and in particular can produce clear structured emulsions. However, such emulsions tend to lose clarity or structural strength during storage. Deviating from &agr;-cellobiose octanonanoate can result in impaired clarity and/or impaired hardness of emulsion sticks. However, acylated cellobiose which contains acyl substituents of formula —O—CO—R in which R represents an n-octyl residue and the percentage Y of the nonanoate acyl substituent —O—CO—R at the anomeric carbon is at least 60% and the percentage A of &agr; anomer is greater than the anomer and not higher than A=74.5 +0.2Y when Y is up to 92% and not higher than A=161−0.74Y when Y is greater than 92% offers the production of sticks combining structurant stability with product clarity and hardness.
摘要翻译：已经发现纤维二糖酯和特别是α-纤维二糖辛酸钠是能够很好地结构水不混溶的液体，特别是可以产生透明的结构化乳液。然而，这种乳液在储存期间往往会失去透明度或结构强度。偏离α-纤维二糖辛酸钠会导致乳液棒的清晰度和/或硬度受损。然而，含有式-O-CO-R的酰基取代基的酰化纤维二糖在其中R代表正辛基残基，而在异头碳处的壬酸酯酰基取代基-O-CO-R的百分比Y至少为60％，当Y大于92％时，当Y大于92％时，α端基异构体的百分比A大于端基异构体，并且不高于A = 74.5±0.2Y，当Y大于92％时，提供棒结合稳定性与产品透明度和硬度相结合。

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