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1. 发明授权

US4787429A Device for coupling a small tube to an apparatus adapted for fitting a syringe to a drug holding bottle 失效
标题翻译：用于将小管耦合到适于将注射器装配到药物保持瓶的装置上的装置
公开(公告)号：US4787429A
公开(公告)日：1988-11-29
申请号：US75776
申请日：1987-07-20
申请人： Luigi Valentini , Mario Coccia
发明人： Luigi Valentini , Mario Coccia
IPC分类号： A61J3/00 , A61J1/00 , A61J1/20 , A61M3/00 , A61M5/00 , A61M5/32 , A61M39/00 , A61M39/02 , A61M39/14 , B65B3/04
CPC分类号： A61J1/2096 , A61M39/14 , A61J1/201 , A61M2039/1027 , A61M2039/1033 , A61M2039/1077 , Y10S285/921
摘要： Device for easily and simply coupling to the free end of a small tube (7) mounted on a transfusion needle an apparatus of the type used for coupling a syringe to a drug holding bottle. The device comprises a hollow shaped body (1) that can be coupled to the small tube (7). An axial passageway (13) in the body (1) is closed by a plug (5). A collar (2) shaped as the mouth of a conventional drug bottle projects from the body (1). The collar (2) extends axially and a continuous annular recess (3) is formed therein. The recess (3) has a profile and arrangment sized and shaped to allow for the teeth projecting from the resilient lugs of the apparatus to which the device is to be coupled to be inserted and locked therein.

2. 发明授权

US4576211A Safety device for connection of a syringe with the mouth or opening of a bottle containing a drug or a small tube for drug delivery from the syringe 失效
标题翻译：用于将注射器与包含药物的瓶口的口或开口连接的用于从注射器药物递送的小管的安全装置
公开(公告)号：US4576211A
公开(公告)日：1986-03-18
申请号：US607502
申请日：1984-05-07
申请人： Luigi Valentini , Mario Coccia
发明人： Luigi Valentini , Mario Coccia
IPC分类号： A61J3/00 , A61J1/00 , A61J1/20 , A61M5/32 , B65B3/04 , A61M5/00
CPC分类号： A61J1/2096 , A61J1/201 , A61J1/2051 , A61J1/2055 , A61J1/2075 , A61J1/2082 , Y10S604/905
摘要： The invention relates to a device to one end of which a syringe can be connected and to the other end of which the mouth or opening of a bottle containing a drug or medicine can be connected. The device comprises a closed chamber having enclosed therein a needle which is in connection with the syringe. Members are provided by means of which the mouth or opening of the bottle is steadily connected to the device and means enabling the needle to perforate a seal plug and then a small rubber plug mounted on the bottle only when the device is blocked onto the bottle so that in any case it cannot be disconnected therefrom. Such a device can be disconnected from the bottle only after the needle has been caused to reenter the closed chamber, so as to prevent any possible dripping of the liquid outside of the device.
摘要翻译：本发明涉及一种装置，其一端可以连接注射器，并且其另一端可以连接含有药物或药物的瓶子的口或开口。该装置包括封闭的腔室，其中封闭有与注射器连接的针头。通过这些装置提供了瓶子的口或开口稳定地连接到装置上的装置，并且使装置能够使针穿孔密封塞，然后仅当装置被阻塞在瓶上时才安装在瓶上的小橡胶塞在任何情况下都不能与其断开连接。只有在针已经重新进入封闭室之后，这种装置才能从瓶中脱离，以防止液体在设备外部滴落。

3. 发明授权

US4995385A Inhaler with regular complete emptying of the capsule 失效
标题翻译：吸入器定期完全排空胶囊
公开(公告)号：US4995385A
公开(公告)日：1991-02-26
申请号：US483744
申请日：1990-02-23
申请人： Luigi Valentini , Giancarlo Ceschel
发明人： Luigi Valentini , Giancarlo Ceschel
IPC分类号： A61M15/00
CPC分类号： A61M15/0028 , A61M15/0041 , A61M2202/064
摘要： An inhaler (10) for administering medicaments in finely divided form contained in capsules comprises a nebulization chamber (42) and a device (16) for piercing the capsule. That end surface of the nebulization chamber containing the holes (48, 49, 50) for the discharge of air laden with the finely divided medicament is shaped such that the capsule, when resting on it, does not impede air passage through any of the discharge holes. The nebulization chamber, at least in that part thereof closest to said discharge holes, tapers towards that end surface of the chamber comprising the discharge holes.

4. 发明授权

US4786281A Device for connecting one end of a liquid medicament delivery cannula to an apparatus for connecting a syringe to a vial containing the medicament 失效
标题翻译：用于将液体药物输送插管的一端连接到用于将注射器连接到含有药物的小瓶的装置的装置
公开(公告)号：US4786281A
公开(公告)日：1988-11-22
申请号：US879886
申请日：1986-06-30
申请人： Luigi Valentini , Mario Coccia
发明人： Luigi Valentini , Mario Coccia
IPC分类号： A61M5/32 , A61J1/00 , A61J1/20
CPC分类号： A61J1/2089 , A61J1/201 , A61J1/2055 , Y10S604/905
摘要： In order to withdraw pharmaceutical products from sterile vials by means of a syringe, apparatus is used on one end of which a syringe possibly containing a liquid solvent is mounted and at the other end of which a seat is provided for housing the mouth of a vial. The syringe needle can puncture the rubber or similar stopper by which the vial is sealed, while the needle itself remains enclosed and protected by said apparatus. The invention relates to a device which, when the vial has been removed, can itself be housed in said apparatus seat to enable the needle to puncture a rubber stopper provided on the device, which is connected to one end of a cannula having for example mounted on its other end a needle for transfusion purposes. In this manner, the liquid can be discharged from the syringe while the needle remains enclosed and protected by the said apparatus.
摘要翻译：为了通过注射器将药物产品从无菌小瓶中取出，在其一端使用装置，其中安装有可能含有液体溶剂的注射器，并且在其另一端设有用于容纳小瓶口部的座。注射器针头可以刺穿小瓶被密封的橡胶或类似的塞子，同时针头本身保持被所述装置封闭和保护。本发明涉及一种装置，当小瓶已被移除时，其本身可以容纳在所述装置座中，以使针能够刺穿设置在装置上的橡胶塞，该橡胶塞连接到具有例如安装的插管的一端另一端用于输血目的。以这种方式，当针保持封闭并被所述装置保护时，液体可以从注射器排出。

5. 发明授权

US4785858A Device for firmly locking a syringe on a body which may be coupled thereto 失效
标题翻译：用于将注射器牢固地锁定在可以联接到其上的主体上的装置
公开(公告)号：US4785858A
公开(公告)日：1988-11-22
申请号：US75683
申请日：1987-07-20
申请人： Luigi Valentini , Mario Coccia
发明人： Luigi Valentini , Mario Coccia
IPC分类号： A61J3/00 , A61J1/00 , A61J1/20 , A61M5/32 , A61M39/02 , B65B3/02
CPC分类号： A61J1/2096 , A61J1/201 , A61J1/2055 , Y10S604/905
摘要： A body is provided with members for coupling it to one end of a bottle or the like. The body has a seat for housing the free end of a syringe, with a hole for allowing for the syringe needle to pass through. The free end of a syringe may be housed and threaded in the seat. On the side opposite surfaces of the body seat and at the syringe end provided for insertion in the seat, there are formed radially projecting longitudinal teeth and slanted resilient fins which are deflected by the teeth as the syringe is threaded to the body. The teeth abut against the fins, thereby preventing the syringe from being screwed off the body.

6. 发明授权

US4069819A Inhalation device 失效
标题翻译：吸入装置
公开(公告)号：US4069819A
公开(公告)日：1978-01-24
申请号：US711962
申请日：1976-08-05
申请人： Luigi Valentini , Michele Maiorano
发明人： Luigi Valentini , Michele Maiorano
IPC分类号： A61M15/00 , A61M15/08
CPC分类号： A61M15/0028 , A61M15/0033 , A61M2202/064 , A61M2206/16
摘要： An inhalation device of cylindrical form is disclosed for the administration of medicaments in finely divided form, having a nebulization chamber for a capsule with the medicament and in which an air passageway is formed in such manner as to set the flowing air in vortical motion. The vortical motion is obtained by means of holes suitably directed or by other means such as inclined surfaces, helicoidal parts or the like. The nebulization chamber is such as to cause the capsule, under the action of the flowing air, to make movements of rotation, precession and vibration about and along its longitudinal axis within the nebulization chamber. A series of air inlet holes may be provided in the periphery of the lower portion of the nebulization chamber, the axes of which are offset from the central axis of the nebulization chamber. One or more push button-actuated needles pierce the capsule and release the powdered medicament.
摘要翻译：公开了一种圆柱形吸入装置，用于以细碎形式施用药物，其具有用于具有药物的胶囊的雾化室，并且其中形成空气通道以使流动空气以涡旋运动的方式形成。涡旋运动是通过适当引导的孔或通过诸如倾斜表面，螺旋部分等的其它方式获得的。雾化室使得胶囊在流动的空气的作用下使其在雾化室内围绕其纵向轴线旋转，进动和振动。可以在雾化室的下部的周边设置一系列进气孔，其轴线偏离雾化室的中心轴线。一个或多个按钮致动的针刺穿胶囊并释放粉末状药物。

7. 发明授权

US5152284A Disposable inhaler with pre-pierced capsule 失效
标题翻译：可预料的吸入器与预制胶囊
公开(公告)号：US5152284A
公开(公告)日：1992-10-06
申请号：US707226
申请日：1991-05-24
申请人： Luigi Valentini , Giancarlo Ceschel
发明人： Luigi Valentini , Giancarlo Ceschel
IPC分类号： A61M15/00
CPC分类号： A61M15/0028 , A61M15/0033 , A61M2202/064
摘要： A disposable inhaler (10; 50; 60) for administering medicaments in finely divided form contained in capsules (22) comprises a body (12) enclosing a nebulization chamber (20), the capsule being inserted into the nebulization chamber during assembly of the component parts of the inhaler. The inhaler does not comprise a device for piercing the capsule. This latter is pierced before its insertion into the inhaler. A cup is provided for preventing escape of the finely divided medicament through the capsule holes (42, 44) until the moment in which the inhaler is used.

8. 发明授权

US4157086A Apparatus for providing skin cuts to a predetermined measure 失效
标题翻译：用于向预定尺寸提供皮肤切割的装置
公开(公告)号：US4157086A
公开(公告)日：1979-06-05
申请号：US865398
申请日：1977-12-29
申请人： Michele Maiorano , Luigi Valentini , Claudio Praga
发明人： Michele Maiorano , Luigi Valentini , Claudio Praga
IPC分类号： A61B5/15 , A61B17/32
CPC分类号： A61B17/32093
摘要： Improved apparatus for providing skin cuts to a predetermined measure in order to determine blood bleeding time, comprising a casing having a cutting blade accommodated therein and restrained to the casing through a pin coupling within an elongate groove. The blade is moved by a rotating spring member to cause its cutting end to project from a casing slit to a degree and travel that are exactly predetermined and repeatable.
摘要翻译：改进的用于向预定措施提供皮肤切割以确定出血时间的装置，包括具有容纳在其中的切割刀片的壳体，并且通过在细长凹槽内的销联接被约束到壳体。刀片通过旋转的弹簧构件移动，使得其切割端从壳体狭缝突出到正好预定并可重复的程度和行程。

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