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1. 发明授权

US09736515B1 Converting digital publications into a format for sending to a user device 有权
公开(公告)号：US09736515B1
公开(公告)日：2017-08-15
申请号：US13535193
申请日：2012-06-27
申请人： Lokesh Joshi , Garett Nell
发明人： Lokesh Joshi , Garett Nell
IPC分类号： H04N21/262 , G06F12/00
CPC分类号： H04N21/262 , G06F12/00 , H04N21/234336 , H04N21/23439 , H04N21/25825 , H04N21/47202
摘要： A computing device receives an electronic publication. The computing device determines a layout for the electronic publication based on a display format in which the electronic publication is to be presented. The computing device converts the electronic publication into a streamable format based on the layout. The computing device receives a request to access the electronic publication from a user device. The computing device transmits contents for one or more pages of the converted electronic publication to the user device.

2. 发明申请

US20130330755A1 ENDO Tv, A NOVEL HIGH MANNOSE-SPECIFIC ENDO-beta-N-ACETYLGLUCOSAMINIDASE FROM TRICHODERMA VIRIDE 审中-公开
标题翻译： ENDO Tv，一种来自TRICHODERMA VIRIDE的新型高含量特异性内切-β-N-乙酰胆碱磷酸酶
公开(公告)号：US20130330755A1
公开(公告)日：2013-12-12
申请号：US13980783
申请日：2012-01-24
申请人： Lokesh Joshi , Jared Gerlach , Michelle Kilcoyne , Mark Farrell
发明人： Lokesh Joshi , Jared Gerlach , Michelle Kilcoyne , Mark Farrell
IPC分类号： C12N9/24
CPC分类号： C12N9/2402 , C12N9/2442 , C12Q1/34 , C12Y302/01096 , G01N2333/942
摘要： The invention relates to an endo-β-N-acetylglucosaminidase enzyme isolatable from the fungus Trichoderma virde and to methods of producing the enzyme and uses of said enzyme.
摘要翻译：本发明涉及可从真菌木霉分离的内切-β-N-乙酰氨基葡糖苷酶，以及生产该酶的方法和所述酶的用途。

3. 发明授权

US08542235B2 System and method for displaying complex scripts with a cloud computing architecture 有权
公开(公告)号：US08542235B2
公开(公告)日：2013-09-24
申请号：US12903703
申请日：2010-10-13
申请人： Lokesh Joshi , Himanshu Joshi
发明人： Lokesh Joshi , Himanshu Joshi
IPC分类号： G06T11/00
CPC分类号： G06T11/00 , G06F17/214 , G06F17/2223 , H04L67/02
摘要： A system and method for displaying complex scripts with a cloud computing architecture may include a client device and a cloud computing server. The client device accesses a web application via the internet and transmits a request containing complex scripts to the cloud computing server. The cloud computing server parses the text and breaks the text down to a sequence of characters of a particular script, and maps the Unicode of each character to a particular glyph to obtain a glyph ID for each character making a one to one relationship. The cloud computing server analyzes each character, assigns, and applies specific font related operations to each glyph. The cloud computing server optimizes and compresses the glyph ID and positioning data, and transmit the compressed data back to the client device to be rendered on the display of the client device.

4. 发明申请

US20120092345A1 SYSTEM AND METHOD FOR DISPLAYING COMPLEX SCRIPTS WITH A CLOUD COMPUTING ARCHITECTURE 有权
标题翻译：使用云计算架构显示复杂脚本的系统和方法
公开(公告)号：US20120092345A1
公开(公告)日：2012-04-19
申请号：US12903703
申请日：2010-10-13
申请人： Lokesh Joshi , Himanshu Joshi
发明人： Lokesh Joshi , Himanshu Joshi
IPC分类号： G06T11/00 , G06F15/16
CPC分类号： G06T11/00 , G06F17/214 , G06F17/2223 , H04L67/02
摘要： A system and method for displaying complex scripts with a cloud computing architecture may include a client device and a cloud computing server. The client device accesses a web application via the internet and transmits a request containing complex scripts to the cloud computing server. The cloud computing server parses the text and breaks the text down to a sequence of characters of a particular script, and maps the Unicode of each character to a particular glyph to obtain a glyph ID for each character making a one to one relationship. The cloud computing server analyzes each character, assigns, and applies specific font related operations to each glyph. The cloud computing server optimizes and compresses the glyph ID and positioning data, and transmit the compressed data back to the client device to be rendered on the display of the client device.
摘要翻译：用于使用云计算架构显示复杂脚本的系统和方法可以包括客户端设备和云计算服务器。客户端设备通过互联网访问Web应用，并将包含复杂脚本的请求发送到云计算服务器。云计算服务器解析文本并将文本分解为特定脚本的一系列字符，并将每个字符的Unicode映射到特定的字形，以获得与一对一关系相关的每个字符的字形ID。云计算服务器分析每个字符，分配和应用与每个字形相关的特定字体相关操作。云计算服务器优化和压缩字形ID和定位数据，并将压缩数据发送回客户端设备，以呈现在客户端设备的显示器上。

5. 发明授权

US08129332B2 Reagents and methods for smooth muscle therapies 失效
标题翻译：用于平滑肌疗法的试剂和方法
公开(公告)号：US08129332B2
公开(公告)日：2012-03-06
申请号：US12101691
申请日：2008-04-11
申请人： Colleen Brophy , Alyssa Panitch , Padmini Komalavilas , Brandon Seal , Lokesh Joshi
发明人： Colleen Brophy , Alyssa Panitch , Padmini Komalavilas , Brandon Seal , Lokesh Joshi
IPC分类号： A61K38/02 , A61K38/16
CPC分类号： C07K5/0819 , A61K38/00 , C07K5/0806 , C07K5/0808 , C07K5/1024 , C07K7/06 , C07K7/08 , C07K14/47
摘要： The present invention provides novel polypeptides comprising heat shock protein 20 (HSP20)-derived polypeptides to treat or inhibit smooth muscle vasospasm, as well to treat and inhibit smooth muscle cell proliferation and migration.
摘要翻译：本发明提供了包含用于治疗或抑制平滑肌血管痉挛的热休克蛋白20（HSP20）衍生多肽的新型多肽，以及治疗和抑制平滑肌细胞增殖和迁移。

6. 发明申请

US20060218669A1 Sialylation of glycoproteins in plants 审中-公开
标题翻译：植物中糖蛋白的唾液酸化
公开(公告)号：US20060218669A1
公开(公告)日：2006-09-28
申请号：US10545252
申请日：2004-02-11
申请人： Lokesh Joshi , Miti Shah
发明人： Lokesh Joshi , Miti Shah
IPC分类号： A01H1/00 , C07K14/415 , C12Q1/68 , C12N15/82 , C12N5/04 , A01H5/00
CPC分类号： C12N15/8257 , C07K14/415 , C12N9/1048 , C12N15/8242 , C12N15/8245 , C12N15/8258 , C12Q1/527
摘要： The presence of sialic acids (SAs) at the non-reducing terminal of various glycoconjugates plays important roles in the function and half-life of glycoproteins in mammals and many species of microorganisms. It has been previously unknown that plant cells have the capacity to sialylate glycoproteins. The present invention discloses the presence of sialylated glycoconjugates and identifies N-acetylneuranminic acid (Neu5Ac) and N-glycolylneuraminic (Neu5Gc) on glycoproteins in suspension-cultured cells of plants, for example, Arabidopsis thaliana (A. thaliana), Nicotiana tabacum (tobacco), and Medicago sativa (alfalfa), extending the complexity of glycan structures known in the plant kingdom. This invention further discloses methods for engineering plants to produce recombinant glcyoproteins.
摘要翻译：在各种糖缀合物的非还原末端存在唾液酸（SA）在哺乳动物和许多种微生物中的糖蛋白的功能和半衰期中起重要作用。以前不知道植物细胞具有唾液酸化糖蛋白的能力。本发明公开了唾液酸化糖缀合物的存在，并鉴定了植物的悬浮培养细胞中的N-乙酰神经元酸（Neu5Ac）和N-羟乙酰神经氨酸（Neu5Gc）在糖蛋白上，例如拟南芥（拟南芥），烟草（烟草））和苜蓿（Medicago sativa）（苜蓿），延长了植物界知道的聚糖结构的复杂性。本发明进一步公开了用于工程植物生产重组蛋白的方法。

7. 发明授权

US09081529B1 Generation of electronic books 有权
标题翻译：一代电子书
公开(公告)号：US09081529B1
公开(公告)日：2015-07-14
申请号：US13530616
申请日：2012-06-22
申请人： Lokesh Joshi , Eric A. Menninga
发明人： Lokesh Joshi , Eric A. Menninga
IPC分类号： G06F3/12 , G06F17/21
CPC分类号： G06F3/1239 , G06F3/1225 , G06F17/211 , G06F17/214
摘要： Described herein are systems and methods for modifying electronic books (“eBooks”). A server processes eBook data to determine portions of one or more source fonts comprising various glyphs used in presenting the eBook. An embedded font is generated which includes those portions of the one or more fonts which are used in the particular eBook data. Because the unused portions of the one or more fonts are omitted, the overall size of the embedded fonts may be less than those of the source fonts. A custom character map may be generated as part of the embedded font which provides for increased document security.
摘要翻译：这里描述了用于修改电子书（“电子书”）的系统和方法。服务器处理电子书数据以确定包括用于呈现电子书的各种字形的一个或多个源字体的部分。生成包括在特定电子书数据中使用的一个或多个字体的那些部分的嵌入字体。因为省略了一个或多个字体的未使用部分，所以嵌入字体的总体尺寸可能小于源字体的大小。可以生成自定义字符映射作为嵌入字体的一部分，其提供增加的文档安全性。

8. 发明授权

US09323726B1 Optimizing a glyph-based file 有权
标题翻译：优化基于字形的文件
公开(公告)号：US09323726B1
公开(公告)日：2016-04-26
申请号：US13535175
申请日：2012-06-27
申请人： Lokesh Joshi , Satishkumar Kothandapani Shanmugasundaram , Nadia C. Payet , Viswanath Sankaranarayanan
发明人： Lokesh Joshi , Satishkumar Kothandapani Shanmugasundaram , Nadia C. Payet , Viswanath Sankaranarayanan
IPC分类号： G09G5/00 , G06F17/22 , G06K9/46 , G06K9/48 , G06T11/20
CPC分类号： G06F17/2223 , G06F17/214 , G06F17/2863 , G06K9/342 , G06K9/4671 , G06K9/481 , G06K9/6814 , G06K2209/01 , G06K2209/013 , G06T11/203
摘要： Systems and methods are provided for optimizing a glyph-based file. Individual components may be identified within glyphs of a file. Each identified component within a glyph may be a portion of the glyph, and may be a joint component or disjoint component. Groupings of components may then be determined, where the groupings are determined based at least in part by identifying similarly shaped components. A representative component may then be selected from each grouping. Composite glyphs may be generated and stored in an optimized file, where each composite glyph includes a reference to at least one representative component.
摘要翻译：提供了系统和方法来优化基于字形的文件。可以在文件的字形内识别各个组件。字形中的每个识别的组件可以是字形的一部分，并且可以是联合组件或不相交组件。然后可以确定组件的组合，其中至少部分地通过识别类似形状的组件来确定分组。然后可以从每个分组中选择代表性组件。可以生成复合字形并将其存储在优化的文件中，其中每个复合字形包括对至少一个代表组件的引用。

9. 发明授权

US08044018B2 Reagents and methods for smooth muscle therapies 失效
标题翻译：用于平滑肌疗法的试剂和方法
公开(公告)号：US08044018B2
公开(公告)日：2011-10-25
申请号：US12101710
申请日：2008-04-11
申请人： Colleen Brophy , Alyssa Panitch , Padmini Komalavilas , Brandon Seal , Lokesh Joshi
发明人： Colleen Brophy , Alyssa Panitch , Padmini Komalavilas , Brandon Seal , Lokesh Joshi
IPC分类号： A61K38/03
CPC分类号： C07K5/0819 , A61K38/00 , C07K5/0806 , C07K5/0808 , C07K5/1024 , C07K7/06 , C07K7/08 , C07K14/47
摘要： The present invention provides novel polypeptides comprising heat shock protein 20 (HSP20)-derived polypeptides to treat or inhibit smooth muscle vasospasm, as well to treat and inhibit smooth muscle cell proliferation and migration.
摘要翻译：本发明提供了包含用于治疗或抑制平滑肌血管痉挛的热休克蛋白20（HSP20）衍生多肽的新型多肽，以及治疗和抑制平滑肌细胞增殖和迁移。

10. 发明申请

US20060035814A1 Reagents and methods for smooth muscle therapies 失效
公开(公告)号：US20060035814A1
公开(公告)日：2006-02-16
申请号：US11078256
申请日：2005-03-11
申请人： Colleen Brophy , Padmini Komalavilas , Alyssa Panitch , Brandon Seal , Lokesh Joshi
发明人： Colleen Brophy , Padmini Komalavilas , Alyssa Panitch , Brandon Seal , Lokesh Joshi
IPC分类号： A61K38/08
CPC分类号： C07K5/0819 , A61K38/00 , C07K5/0806 , C07K5/0808 , C07K5/1024 , C07K7/06 , C07K7/08 , C07K14/47
摘要： The present invention provides novel polypeptides comprising heat shock protein 20 (HSP20)-derived polypeptides to treat or inhibit smooth muscle vasospasm, as well to treat and inhibit smooth muscle cell proliferation and migration.

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