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1. 发明申请

US20130053269A1 Primer Sequences for Amplification of Sea Otter Genes, and Methods of Use Thereof 审中-公开
标题翻译：用于扩增海獭基因的引物序列及其使用方法
公开(公告)号：US20130053269A1
公开(公告)日：2013-02-28
申请号：US13580015
申请日：2011-02-21
申请人： A. Keith Miles , Lizabeth Bowen
发明人： A. Keith Miles , Lizabeth Bowen
IPC分类号： C12Q1/68 , C40B40/06 , C40B30/04 , C07H21/04
CPC分类号： C12Q1/6883 , C12Q1/6888 , C12Q2600/158
摘要： Gene expression technologies have the exciting potential of providing methods for monitoring long-term effects of contaminants and disease on free-ranging marine wildlife species. An added benefit is that these methods may elucidate the mechanisms by which these stressors can deleteriously affect an individual over a long period, and thereby aid in the design of therapeutic and preventative strategies to treat and protect susceptible individuals and populations at risk from oil exposure. Our presentation will assess specific quantifiable genetic markers that can signify persistent pathological and physiological injury associated primarily with chronic hydrocarbon exposure. Using empirical evidence from captive animals and recent captures, we will discuss how we are developing an understanding of gene expression as it relates to the immune system of the sea otter and other marine megafauna, and the potential effects of contaminants or disease.
摘要翻译：基因表达技术具有提供监测污染物和疾病对自由海洋野生动物物种长期影响的方法的潜力。另外一个好处是，这些方法可以阐明这些应激源可以长时间有害地影响个体的机制，从而有助于设计治疗和预防策略来治疗和保护易受暴露的风险的个体和群体。我们的演讲将评估具体的可量化的遗传标记，可以表示主要与慢性碳氢化合物暴露相关的持续性病理和生理损伤。使用圈养动物的实证证据和最近的捕获，我们将讨论我们如何开发对基因表达的理解，因为它与海獭和其他海洋巨噬细胞的免疫系统以及污染物或疾病的潜在影响有关。

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