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    • 5. 发明申请
    • LIPOPROTEIN SURFACTANT
    • LIPOPROTEIN表面活性剂
    • US20100330596A1
    • 2010-12-30
    • US12636320
    • 2009-12-11
    • Lindy Jane Murphy
    • Lindy Jane Murphy
    • C12Q1/61C12M1/40C12Q1/60
    • C12Q1/004C12Q1/60C12Q1/61
    • Surfactants are provided which are particularly useful for carrying out cholesterol and triglyceride tests. These surfactants have particularly fast kinetics of response to cholesterol, cholesterol ester and triglyceride in all lipoprotein particles. Cholesterol or triglyceride sensors incorporating these surfactants therefore provide reliable measurements of the total cholesterol or triglyceride content of a sample in a short period of time. Also provided are a sensor comprising the subject surfactants for determining the amount of triglyceride and/or cholesterol in a sample, as well as methods for determining the amount of cholesterol and/or triglyceride in a sample, the method comprising: contacting the sample with a surfactant as defined above; and determining the amount of cholesterol and/or triglyceride present.
    • 提供了对进行胆固醇和甘油三酯测试特别有用的表面活性剂。 这些表面活性剂对所有脂蛋白颗粒中的胆固醇,胆固醇酯和甘油三酯都具有特别快的反应动力学。 因此,结合这些表面活性剂的胆固醇或甘油三酸酯传感器可以在短时间内对样品的总胆固醇或甘油三酯含量进行可靠的测量。 还提供了包含用于测定样品中甘油三酯和/或胆固醇的量的受试表面活性剂的传感器,以及用于测定样品中胆固醇和/或甘油三酯的量的方法,所述方法包括:将样品与 表面活性剂; 并确定存在的胆固醇和/或甘油三酯的量。