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1. 发明申请

US20090293633A1 Uniform Shear Application System and Methods Relating Thereto 有权
标题翻译：均匀剪切应用系统及其相关方法
公开(公告)号：US20090293633A1
公开(公告)日：2009-12-03
申请号：US12536594
申请日：2009-08-06
申请人： Fernando J. Muzzio , Lev Tsygan , Semen Dukler
发明人： Fernando J. Muzzio , Lev Tsygan , Semen Dukler
IPC分类号： G01N3/24
CPC分类号： G01N3/24 , G01N33/15 , G01N2033/0091
摘要： Disclosed herein is a shear application system for applying substantially uniform amounts of shear throughout a powder sample. The shear application system preferably includes a cylinder assembly having an inner cylinder, a housing, an inner set of lugs, and an outer set of lugs. The inner cylinder has an external cylindrical surface and the housing has an internal cylindrical surface concentric with said external cylindrical surface. The internal and external cylindrical surfaces form an annular chamber therebetween. Each one of the lugs of the inner set extend radially outward from the external cylindrical surface, and each one of the lugs of the outer set extend radially inward from the internal cylindrical surface and are substantially uniformly spaced. The shear application system preferably includes drive means mechanically connected to the inner cylinder and control means electrically connected to the drive means.
摘要翻译：本文公开了一种用于在整个粉末样品中施加基本均匀量的剪切的剪切施加系统。剪切施加系统优选地包括具有内筒，壳体，内套件和外套件的圆柱体组件。内筒具有外圆柱形表面，并且壳体具有与所述外圆柱表面同心的内圆柱表面。内部和外部圆柱形表面在它们之间形成环形室。内部组件的每个凸耳从外部圆柱形表面径向向外延伸，并且外部组件的每个凸耳从内部圆柱形表面径向向内延伸并且基本均匀地间隔开。剪切施加系统优选地包括机械地连接到内筒的驱动装置和电连接到驱动装置的控制装置。

2. 发明授权

US07571871B2 Uniform shear application system and methods relating thereto 有权
标题翻译：均匀剪切应用系统及其相关方法
公开(公告)号：US07571871B2
公开(公告)日：2009-08-11
申请号：US11267039
申请日：2005-11-04
申请人： Fernando J. Muzzio , Lev Tsygan , Semen Dukler
发明人： Fernando J. Muzzio , Lev Tsygan , Semen Dukler
IPC分类号： B02C17/00 , B02C23/02
CPC分类号： G01N3/24 , G01N33/15 , G01N2033/0091
摘要： Disclosed herein is a shear application system for applying substantially uniform amounts of shear throughout a powder sample. The shear application system preferably includes a cylinder assembly having an inner cylinder, a housing, an inner set of lugs, and an outer set of lugs. The inner cylinder has an external cylindrical surface and the housing has an internal cylindrical surface concentric with said external cylindrical surface. The internal and external cylindrical surfaces form an annular chamber therebetween. Each one of the lugs of the inner set extend radially outward from the external cylindrical surface, and each one of the lugs of the outer set extend radially inward from the internal cylindrical surface and are substantially uniformly spaced. The shear application system preferably includes drive means mechanically connected to the inner cylinder and control means electrically connected to the drive means.
摘要翻译：本文公开了一种用于在整个粉末样品中施加基本均匀量的剪切的剪切施加系统。剪切施加系统优选地包括具有内筒，壳体，内套件和外套件的圆柱体组件。内筒具有外圆柱形表面，并且壳体具有与所述外圆柱表面同心的内圆柱表面。内部和外部圆柱形表面在它们之间形成环形室。内部组件的每个凸耳从外部圆柱形表面径向向外延伸，并且外部组件的每个凸耳从内部圆柱形表面径向向内延伸并且基本均匀地间隔开。剪切施加系统优选地包括机械地连接到内筒的驱动装置和电连接到驱动装置的控制装置。

3. 发明申请

US20090115090A1 SYSTEM AND METHOD FOR OPTIMIZING TABLET FORMATION BY A ROTARY PRESS MACHINE 失效
标题翻译：旋转式压片机优化板片形成系统及方法
公开(公告)号：US20090115090A1
公开(公告)日：2009-05-07
申请号：US11934488
申请日：2007-11-02
申请人： Semen Dukler , Lev Tsygan , Michael Levin
发明人： Semen Dukler , Lev Tsygan , Michael Levin
IPC分类号： B30B15/30 , B30B11/00 , B30B11/08
CPC分类号： B30B11/08
摘要： Rotary press machine including dies, pairs of upper and lower punches with a part of each lower punch being movable in a respective die to selectively enable formation of a cavity in the die, a feeding system for feeding powder material into the cavities, when present, in a feeding stage, a pressing system for pressing the upper and lower punches together in a pressing stage and a tablet ejection system for ejecting formed tablets from the dies in a tablet ejection stage. The upper and lower punches are rotated sequentially through the feeding stage, the pressing stage and the tablet ejection stage to thereby enable formation of tablets if powder material is feed into the cavities in the dies. To enable selective formation of tablets and thereby optimize production thereof, an adjustment mechanism is provided and enables selective formation of the cavities in the dies.
摘要翻译：包括模具的旋转压力机成对的上下冲头，每个下冲头的一部分可在相应的模具中移动，以选择性地在模具中形成空腔，用于将粉料输送到空腔中的进料系统，在进料阶段，用于在压制阶段中将上冲头和下冲头压在一起的压制系统和用于在片剂喷射阶段从模具中排出成形片剂的片剂排出系统。上冲头和下冲头依次通过进料阶段，加压阶段和片剂喷射阶段旋转，从而如果粉末材料进入模具中的空腔，则能够形成片剂。为了能够选择性地形成片剂并由此优化其生产，提供了调节机构，并且能够选择性地形成模具中的空腔。

4. 发明授权

US06482338B1 Press simulation apparatus and methods 失效
标题翻译：模拟装置和方法
公开(公告)号：US06482338B1
公开(公告)日：2002-11-19
申请号：US09604711
申请日：2000-06-27
申请人： Michael Levin , Lev Tsygan , Semen Dukler
发明人： Michael Levin , Lev Tsygan , Semen Dukler
IPC分类号： B29C4304
CPC分类号： B30B11/14 , B30B11/08
摘要： This disclosure concerns an apparatus and methods for reproducing compaction and ejection events in a plurality of press machines. Each press machine has at least one die opening wherein a compound is placed to be compressed at least once between upper and lower punches sliding inside the said die whereupon the compressed compound is ejected from the die cavity. The apparatus and methods ensure that the plurality of compression and ejection events have the same exact speed, profile curvature, and pressure or force as on any pre-specified press machine by matching the timing and geometrical path of the punch movements as well as the depth of fill of the die. The linear speed of the punches is matched by a computer controlling the programmable motor of the die carrier. The path protiles of the punches are matched mechanically by means of interchangeable rollers and cams with the predefined geometry. The pressure or forces of the matching events are controlled and adjusted by means of the positioning of the lower punch in the die.
摘要翻译：本公开涉及用于在多台冲压机中再现压缩和喷射事件的装置和方法。每个压力机具有至少一个模具开口，其中化合物被放置为在上模和下冲头之间至少压缩一次，在所述模具内滑动，从而压缩的化合物从模腔中排出。该设备和方法确保了多个压缩和喷射事件具有与任何预先指定的压力机上相同的精确速度，轮廓曲率以及压力或力，通过匹配冲头运动的时间和几何路径以及深度填充模具。冲头的线速度通过控制模具载体的可编程马达的计算机进行匹配。冲孔的路径通过可互换的滚子和具有预定几何形状的凸轮进行机械匹配。匹配事件的压力或力通过下冲头在模具中的定位来控制和调整。

5. 发明申请

US20110024937A1 Tablet Formation System for Fully-Loaded Presses 审中-公开
标题翻译：全压机压片机组成系统
公开(公告)号：US20110024937A1
公开(公告)日：2011-02-03
申请号：US12512718
申请日：2009-07-30
申请人： Semen Dukler , Lev Tsygan , Michael Levin
发明人： Semen Dukler , Lev Tsygan , Michael Levin
IPC分类号： B29C43/34 , B29C43/58
CPC分类号： B30B11/08 , B29C43/08 , B29C43/58 , B29C2043/3283 , B29C2043/3618 , B29C2043/5833 , B29C2043/5883
摘要： Rotary press machine including dies, pairs of upper and lower punches with a part of each lower punch being movable in a respective die to selectively enable formation of a cavity in the die, a feeding system for feeding powder material into the cavities, when present, in a feeding stage, a pressing system for pressing the upper and lower punches together in a pressing stage and a tablet ejection system for ejecting formed tablets from the dies in a tablet ejection stage. The upper and lower punches are rotated sequentially through the feeding stage, the pressing stage, and the tablet ejection stage to thereby enable formation of tablets if powder material is feed into the cavities in the dies. To enable selective formation of tablets and thereby optimize production thereof, an adjustment mechanism is provided and enables selective formation of the cavities in the dies. The adjustment mechanism may comprise removeable rings attached to at least one, or to a plurality of lower punches, which rings are selectively engaged by the adjustment mechanism.
摘要翻译：包括模具的旋转压力机成对的上下冲头，每个下冲头的一部分可在相应的模具中移动，以选择性地在模具中形成空腔，用于将粉料输送到空腔中的进料系统，在进料阶段，用于在压制阶段中将上冲头和下冲头压在一起的压制系统和用于在片剂喷射阶段从模具中排出成形片剂的片剂排出系统。上冲头和下冲头依次通过进料阶段，加压阶段和片剂喷射阶段旋转，从而如果将粉末材料进料到模具中的空腔中，则能够形成片剂。为了能够选择性地形成片剂并由此优化其生产，提供了调节机构，并且能够选择性地形成模具中的空腔。调节机构可以包括附接到至少一个或多个下冲头的可移除环，该多个下冲头通过调节机构选择性地接合该环。

6. 发明授权

US07553436B2 System and method for optimizing tablet formation by a rotary press machine 失效
标题翻译：通过旋转压力机优化片剂形成的系统和方法
公开(公告)号：US07553436B2
公开(公告)日：2009-06-30
申请号：US11934488
申请日：2007-11-02
申请人： Semen Dukler , Lev Tsygan , Michael Levin
发明人： Semen Dukler , Lev Tsygan , Michael Levin
IPC分类号： B29C43/08
CPC分类号： B30B11/08
摘要： Rotary press machine including dies, pairs of upper and lower punches with a part of each lower punch being movable in a respective die to selectively enable formation of a cavity in the die, a feeding system for feeding powder material into the cavities, when present, in a feeding stage, a pressing system for pressing the upper and lower punches together in a pressing stage and a tablet ejection system for ejecting formed tablets from the dies in a tablet ejection stage. The upper and lower punches are rotated sequentially through the feeding stage, the pressing stage and the tablet ejection stage to thereby enable formation of tablets if powder material is feed into the cavities in the dies. To enable selective formation of tablets and thereby optimize production thereof, an adjustment mechanism is provided and enables selective formation of the cavities in the dies.
摘要翻译：包括模具的旋转压力机成对的上下冲头，每个下冲头的一部分可在相应的模具中移动，以选择性地在模具中形成空腔，用于将粉料输送到空腔中的进料系统，在进料阶段，用于在压制阶段中将上冲头和下冲头压在一起的压制系统和用于在片剂喷射阶段从模具中排出成形片剂的片剂排出系统。上冲头和下冲头依次通过进料阶段，加压阶段和片剂喷射阶段旋转，从而如果粉末材料进入模具中的空腔，则能够形成片剂。为了能够选择性地形成片剂并由此优化其生产，提供了调节机构，并且能够选择性地形成模具中的空腔。

7. 发明申请

US20070113673A1 Uniform shear application system and methods relating thereto 有权
标题翻译：均匀剪切应用系统及其相关方法
公开(公告)号：US20070113673A1
公开(公告)日：2007-05-24
申请号：US11267039
申请日：2005-11-04
申请人： Fernando Muzzio , Lev Tsygan , Semen Dukler
发明人： Fernando Muzzio , Lev Tsygan , Semen Dukler
IPC分类号： G01N3/24
CPC分类号： G01N3/24 , G01N33/15 , G01N2033/0091
摘要： Disclosed herein is a shear application system for applying substantially uniform amounts of shear throughout a powder sample. The shear application system preferably includes a cylinder assembly having an inner cylinder, a housing, an inner set of lugs, and an outer set of lugs. The inner cylinder has an external cylindrical surface and the housing has an internal cylindrical surface concentric with said external cylindrical surface. The internal and external cylindrical surfaces form an annular chamber therebetween. Each one of the lugs of the inner set extend radially outward from the external cylindrical surface, and each one of the lugs of the outer set extend radially inward from the internal cylindrical surface and are substantially uniformly spaced. The shear application system preferably includes drive means mechanically connected to the inner cylinder and control means electrically connected to the drive means.
摘要翻译：本文公开了一种用于在整个粉末样品中施加基本均匀量的剪切的剪切施加系统。剪切施加系统优选地包括具有内筒，壳体，内套件和外套件的圆柱体组件。内筒具有外圆柱形表面，并且壳体具有与所述外圆柱表面同心的内圆柱表面。内部和外部圆柱形表面在它们之间形成环形室。内部组件的每个凸耳从外部圆柱形表面径向向外延伸，并且外部组件的每个凸耳从内部圆柱形表面径向向内延伸并且基本均匀地间隔开。剪切施加系统优选地包括机械地连接到内筒的驱动装置和电连接到驱动装置的控制装置。

8. 发明授权

US6106262A Press simulation apparatus 失效
标题翻译：按模拟装置
公开(公告)号：US6106262A
公开(公告)日：2000-08-22
申请号：US998536
申请日：1997-12-25
申请人： Michael Levin , Lev Tsygan , Semen Dukler
发明人： Michael Levin , Lev Tsygan , Semen Dukler
IPC分类号： B30B11/08 , B30B11/14 , B29C43/24
CPC分类号： B30B11/14 , B30B11/08
摘要： An apparatus for reproducing compaction and ejection events in a plurality of press machines is disclosed. Each press machine has at least one die opening wherein a compound is placed to be compressed at least once between upper and lower punches sliding inside the said die whereupon the compressed compound is ejected from the die cavity. The apparatus and methods ensure that the plurality of compression and ejection events have the same exact speed, profile curvature, and pressure or force as on any pre-specified press machine by matching the timing and geometrical path of the punch movements as well as the depth of fill of the die. The linear speed of the punches is matched by a computer controlling the programmable motor of the die carrier. The path profiles of the punches are matched mechanically by means of interchangeable rollers and cams with the predefined geometry. The pressure or forces of the matching events are controlled and adjusted by means of the positioning of the lower punch in the die.
摘要翻译：公开了一种用于在多台压力机中再现压实和喷射事件的装置。每个压力机具有至少一个模具开口，其中化合物被放置为在上模和下冲头之间至少压缩一次，在所述模具内滑动，从而压缩的化合物从模腔中排出。该设备和方法确保了多个压缩和喷射事件具有与任何预先指定的压力机上相同的精确速度，轮廓曲率以及压力或力，通过匹配冲头运动的时间和几何路径以及深度填充模具。冲头的线速度通过控制模具载体的可编程马达的计算机进行匹配。冲孔的路径轮廓通过可互换的滚子和凸轮与预定义的几何形状进行机械匹配。匹配事件的压力或力通过下冲头在模具中的定位来控制和调整。

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