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    • 1. 发明授权
    • Silicone-containing polymers, compositions and improved oxygen permeable
hydrophilic contact lenses
    • 含硅氧烷的聚合物,组合物和改进的透氧亲水性隐形眼镜
    • US5314961A
    • 1994-05-24
    • US867825
    • 1992-04-09
    • Waifong L. AntonHenry D. ColemanMohammed I. AliLester Weintraub
    • Waifong L. AntonHenry D. ColemanMohammed I. AliLester Weintraub
    • C08F287/00C08F293/00G02B1/04C08F271/02C08F275/00
    • G02B1/043C08F287/00C08F293/00
    • The present invention relates to novel copolymers and contact lenses made from these copolymers comprising preformed silicone-containing acrylic star polymers, graft copolymers and macromonomers, preparation of these contact lenses and a therapeutic method for treating patients with visual impairment.Described is a composition comprising at least about 10% by weight of a preformed silicone-containing acrylic copolymer and no more than about 90% by weight of a matrix formed from the random polymerization of a mixture of monomers. The mixture of monomers comprises at least one hydrophilic monomer and at least about 5% by weight of a polysiloxanylalkylester of an alpha, beta unsaturated acid and optionally, monomers selected from the group consisting of esters of alpha, beta-unsaturated acids and crosslinking monomers. The preformed silicone-containing acrylic copolymer is preferably copolymerized throughout the matrix. The final compositions are hydrated to a final water content of at least about 10% by weight.
    • 本发明涉及由这些共聚物制成的新型共聚物和隐形眼镜,包括预先形成的含硅酮的丙烯酸类星形聚合物,接枝共聚物和大分子单体,这些隐形眼镜的制备以及用于治疗视力障碍的患者的治疗方法。 描述了包含至少约10重量%的预成型含硅氧烷的丙烯酸共聚物和不超过约90重量%的由单体混合物的无规聚合形成的基体的组合物。 单体的混合物包含至少一种亲水单体和至少约5重量%的α,β不饱和酸的聚硅氧烷基烷基酯和任选的选自α,β-不饱和酸和交联单体的酯的单体。 预制的含有机硅的丙烯酸共聚物优选在整个基质中共聚。 将最终组合物水合至至少约10重量%的最终含水量。