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1. 发明授权

US07297536B2 Inducible protein expression system 失效
标题翻译：诱导蛋白表达系统
公开(公告)号：US07297536B2
公开(公告)日：2007-11-20
申请号：US10763976
申请日：2004-01-23
申请人： Jerome S. Harms , Gary A. Splitter , Kurt A. Eakle , Robert D. Bremel
发明人： Jerome S. Harms , Gary A. Splitter , Kurt A. Eakle , Robert D. Bremel
IPC分类号： C12N15/85 , C12N15/864 , C12N15/861 , C12N15/867 , C12N15/48 , C12N15/49 , A61K48/00
CPC分类号： C12N15/86 , C12N2740/14043 , C12N2830/00 , C12N2830/50 , C12N2830/60
摘要： Inducible gene expression systems and a method thereof. A first inducible gene expression system includes a first vector comprising at least one retroviral promoter and at least one factor to induce the retroviral promoter. At least one gene product is expressed in proportion to retroviral promoter induction. The method includes providing a first vector comprising at least one retroviral promoter and providing at least one factor corresponding to the retroviral promoter. The retroviral promoter is induced with the at least one factor. At least one protein is expressed based on the induction of the retroviral promoter. A second inducing expression system includes a first vector comprising at least one retroviral promoter, an inducer for the retroviral promoter, and at least one protein expressed in proportion to retroviral promoter induction.
摘要翻译：诱导型基因表达系统及其方法。第一诱导型基因表达系统包括第一载体，其包含至少一个逆转录病毒启动子和至少一个诱导逆转录病毒启动子的因子。至少一种基因产物与逆转录病毒启动子诱导成比例地表达。该方法包括提供包含至少一个逆转录病毒启动子并提供至少一个与逆转录病毒启动子相对应的因子的第一载体。用至少一个因子诱导逆转录病毒启动子。基于逆转录病毒启动子的诱导表达至少一种蛋白质。第二诱导表达系统包括第一载体，其包含至少一个逆转录病毒启动子，用于逆转录病毒启动子的诱导子，和至少一种与逆转录病毒启动子诱导成比例的蛋白质。

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