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1. 发明授权

US08669080B2 Mutated D-aminotransferase and method for producing optically active glutamic acid derivatives using the same 失效
标题翻译：突变的D-氨基转移酶及其制备使用其的光学活性谷氨酸衍生物的方法
公开(公告)号：US08669080B2
公开(公告)日：2014-03-11
申请号：US12055605
申请日：2008-03-26
申请人： Masakazu Sugiyama , Kunihiko Watanabe , Tatsuki Kashiwagi , Ei-ichiro Suzuki
发明人： Masakazu Sugiyama , Kunihiko Watanabe , Tatsuki Kashiwagi , Ei-ichiro Suzuki
IPC分类号： C12P13/14 , C12P21/06 , C12N1/21 , C07H21/04
CPC分类号： C12N9/1096 , C12P17/10
摘要： A D-aminotransferase can be modified so as to efficiently produce (2R,4R)-monatin having high sweetness intensity from 4-(indol-3-ylmethyl)-4-hydroxy-2-oxoglutaric acid by mutating the amino acid sequence of a wild-type D-aminotransferase represented in SEQ ID NO:4.
摘要翻译：可以修饰D-氨基转移酶，以便通过将氨基酸序列的突变来有效地从4-（吲哚-3-基甲基）-4-羟基-2-氧代戊二酸生成具有高甜度强度的（2R，4R） SEQ ID NO：4所示的野生型D-氨基转移酶。

2. 发明申请

US20130084610A1 NOVEL OXIDASE GENE AND METHOD FOR PRODUCING 3-INDOLE-PYRUVIC ACID BY UTILIZING THE GENE 有权
标题翻译：新型氧化酶基因及利用该基因生产3-吲哚酸的方法
公开(公告)号：US20130084610A1
公开(公告)日：2013-04-04
申请号：US13684888
申请日：2012-11-26
申请人： Yasuaki TAKAURA , Seiichi Hara , Toshiki Taba , Shunichi Suzuki , Masakazu Sugiyama , Kunihiko Watanabe , Kenzo Yokozeki
发明人： Yasuaki TAKAURA , Seiichi Hara , Toshiki Taba , Shunichi Suzuki , Masakazu Sugiyama , Kunihiko Watanabe , Kenzo Yokozeki
IPC分类号： C12P17/10 , C12N9/00
CPC分类号： C12P17/10 , C12N9/0022
摘要： It is an object of the present invention to provide a procedure for realizing inexpensive and simple production of 3-indole-pyruvic acid. A transformant is made using a polynucleotide having a specific nucleotide sequence encoding a protein having an oxidase activity, and oxidase is generated by culturing the transformant in a medium to accumulate the oxidase in the medium and/or the transformant. Further, tryptophan is converted into 3-indole-pyruvic acid in the presence of the transformant and/or a culture thereof to produce 3-indole-pyruvic acid.
摘要翻译：本发明的目的是提供一种实现廉价且简单的3-吲哚 - 丙酮酸生产的方法。使用具有编码具有氧化酶活性的蛋白质的特异性核苷酸序列的多核苷酸制备转化体，通过在培养基中培养转化体以在培养基和/或转化体中积累氧化酶而产生氧化酶。此外，在转化体和/或其培养物存在下，将色氨酸转化为3-吲哚 - 丙酮酸，生成3-吲哚 - 丙酮酸。

3. 发明申请

US20120040416A1 NOVEL ALDOLASE AND PRODUCTION PROCESS OF SUBSTITUTED ALPHA-KETO ACIDS 失效
标题翻译：新型ALDOLASE和替代ALPHA-KETO酸的生产方法
公开(公告)号：US20120040416A1
公开(公告)日：2012-02-16
申请号：US13250359
申请日：2011-09-30
申请人： Masakazu SUGIYAMA , Kunihiko Watanabe , Shigeru Kawahara
发明人： Masakazu SUGIYAMA , Kunihiko Watanabe , Shigeru Kawahara
IPC分类号： C12P17/10 , C12P7/42 , C12P7/50
CPC分类号： C12N9/88 , C12P7/42 , C12P7/50 , C12P13/04 , C12P17/10
摘要： 4-(Indol-3-ylmethyl)-4-hydroxy-2-oxoglutarate, which is useful as an intermediate in the synthesis of monatin, may be synthesized from indole pyruvic acid and pyruvic acid (and/or oxaloacetic acid) by using a novel aldolase derived from the genus Pseudomonas, Erwinia, Flavobacterium, or Xanthomonas.
摘要翻译：可用作合成莫纳甜的中间体的4-（吲哚-3-基甲基）-4-羟基-2-氧戊二酸，可以由吲哚丙酮酸和丙酮酸（和/或草酰乙酸）通过使用衍生自假单胞菌属，欧文氏菌属，黄杆菌属或黄单胞菌属的新型醛缩酶。

4. 发明授权

US08048647B2 Aldolase, and method for producing optically active IHOG and monatin 失效
标题翻译：醛缩酶，以及用于制备光学活性的IHOG和莫纳甜的方法
公开(公告)号：US08048647B2
公开(公告)日：2011-11-01
申请号：US12635994
申请日：2009-12-11
申请人： Masakazu Sugiyama , Kunihiko Watanabe , Kenichi Mori , Hiroyuki Nozaki
发明人： Masakazu Sugiyama , Kunihiko Watanabe , Kenichi Mori , Hiroyuki Nozaki
IPC分类号： C12P13/04 , C12P17/10 , C12N9/10 , C12N1/21
CPC分类号： C12P17/10 , C12N9/88
摘要： The present invention relates to a method for producing optically active IHOG, which can in turn be used for the production of monatin. The present invention further relates to a method for producing optically active monatin, and aldolase used for these methods. As such, the present invention enables the synthesis of 4-(Indole-3-ylmethyl)-4-hydroxy-2-oxoglutaric acid with high optical purity, which is useful as an intermediate in the synthesis of optically active monatin, from indole pyruvic acid and pyruvic acid (or oxaloacetic acid).
摘要翻译：本发明涉及一种用于制备光学活性的IHOG的方法，其可以用于制备莫纳甜。本发明还涉及用于制备光学活性莫纳甜的方法和用于这些方法的醛缩酶。因此，本发明能够合成具有高光学纯度的4-（吲哚-3-基甲基）-4-羟基-2-氧代戊二酸，其可用作在光学活性莫纳甜的合成中的吲哚丙酮酸的中间体酸和丙酮酸（或草酰乙酸）。

5. 发明授权

US08013249B2 Shield conductor and shield conductor manufacturing method 失效
标题翻译：屏蔽导体和屏蔽导体制造方法
公开(公告)号：US08013249B2
公开(公告)日：2011-09-06
申请号：US12312466
申请日：2007-11-23
申请人： Kunihiko Watanabe , Hideo Miyaki , Katsutoshi Izawa
发明人： Kunihiko Watanabe , Hideo Miyaki , Katsutoshi Izawa
IPC分类号： H01R9/05
CPC分类号： H01B7/426 , H01B7/16 , H01B7/17 , H01B13/2633 , Y10T29/49117
摘要： A shield conductor Wa comprises: a metallic pipe 20, a wire 10 to be inserted into the pipe 20, and a groove-like fitting member 22 provided in the pipe 20 as extending along the direction of axis of the wire 10, and at the same time, attached tightly to the circumference of the wire. With the inner surface of the groove-like fitting member 22 in the pipe 20 attached tightly to the circumference of the wire 10, the heat generated in the wire 10 is transmitted directly to the pipe 20, and then released to the air from the circumference of the pipe 20. This improves radiation performance of the shield conductor Wa.
摘要翻译：屏蔽导体Wa包括：金属管20，插入管20中的线10和设置在管20中的沿着线10的轴线方向延伸的槽状配合构件22，并且在同时，紧紧贴在电线的圆周上。由于配管20内的槽状配合构件22的内表面与电线10的圆周紧密地配合，所以在电线10中产生的热量直接传递给配管20，从而从周围排出空气这改善了屏蔽导体Wa的辐射性能。

6. 发明申请

US20100327287A1 Display Device And Manufacturing Method Of The Same 有权
标题翻译：显示器件及其制造方法
公开(公告)号：US20100327287A1
公开(公告)日：2010-12-30
申请号：US12881560
申请日：2010-09-14
申请人： Miyo Ishii , Junichi Uehara , Kunihiko Watanabe
发明人： Miyo Ishii , Junichi Uehara , Kunihiko Watanabe
IPC分类号： H01L33/08
CPC分类号： H01L29/41733 , H01L27/124 , H01L27/1288
摘要： A display device includes a sequentially stacked body formed of a gate signal line, an insulation film, a semiconductor layer and a conductor layer on a substrate. The conductive layer forms a drain electrode and a source electrode of a thin film transistor which are arranged with a channel region of the semiconductor layer therebetween, and one of the drain and source electrode is formed in an approximately U shape having an open-ended one end side and a connecting portion on another end side so that the one electrode surrounds a distal end portion of another electrode as viewed in a plan view, and a projecting portion is formed on a side of the connecting portion opposite to the another electrode.
摘要翻译：显示装置包括在基板上由栅极信号线，绝缘膜，半导体层和导体层形成的顺序层叠体。导电层形成漏极电极和薄膜晶体管的源电极，其间设置有半导体层的沟道区域，漏极和源极之一形成为具有开口端的大致U形端部侧和另一端侧的连接部分，使得一个电极围绕另一个电极的远端部分，如在平面图中所示，并且突出部分形成在与另一个电极相对的连接部分的一侧上。

7. 发明授权

US07700879B2 Shield conductor and method of producing thereof 失效
标题翻译：屏蔽导体及其制造方法
公开(公告)号：US07700879B2
公开(公告)日：2010-04-20
申请号：US11793333
申请日：2006-04-04
申请人： Kunihiko Watanabe
发明人： Kunihiko Watanabe
IPC分类号： H01B7/00
CPC分类号： H01B7/16 , H01B7/428 , Y10T29/53243
摘要： An improved shield connector and a method of making the same include an electric wire having a conductor with an insulation coating and a metallic pipe. The electric wire is positioned in the metallic pipe. A filler is located inside the pipe, between the electric wire and the pipe, and the filler has a heat conductivity higher than that of air.
摘要翻译：改进的屏蔽连接器及其制造方法包括具有绝缘涂层和金属管的导体的电线。电线位于金属管中。填料位于管内，电线和管之间，填料的导热系数高于空气。

8. 发明申请

US20100093411A1 Portable Wireless Device 有权
标题翻译：便携式无线设备
公开(公告)号：US20100093411A1
公开(公告)日：2010-04-15
申请号：US12513144
申请日：2007-10-29
申请人： Kenji Waku , Kunihiko Watanabe , Katsuji Morishita , Yasuhiro Abe , Junichi Kondo , Mitsuhiro Nishizono , Tadashi Koyama
发明人： Kenji Waku , Kunihiko Watanabe , Katsuji Morishita , Yasuhiro Abe , Junichi Kondo , Mitsuhiro Nishizono , Tadashi Koyama
IPC分类号： H04M1/00 , H04W88/02
CPC分类号： H04M1/0277 , H01Q1/243 , H01Q1/38 , H04M1/0214
摘要： The present invention has an object of attaining further miniaturization and reducing the thickness of a portable wireless device with a built-in antenna. The cellular telephone device 1 according to the one embodiment of the present invention includes a case body 60 having a first case portion 62 which is arranged so as to cover the electronic components, along with being electrically conductive to the reference potential pattern, and a nonconductive second case portion 64 arranged to be continuous to the first case portion 62 along with being arranged in the outer periphery of the circuit substrate 70. In the portion that is arranged to be layered in the second case portion 64 in a flexible wiring substrate 50, an antenna element 66 is arranged.
摘要翻译：本发明的目的是通过内置天线进一步小型化和减小便携式无线装置的厚度。根据本发明的一个实施例的蜂窝电话设备1包括壳体60，壳体60具有第一壳体部分62，其布置成覆盖电子部件，以及与参考电位图案导电，以及非导电第二壳体部分64布置成与电路基板70的外周一起布置成与第一壳体部分62连续。在柔性布线基板50中布置成层叠在第二壳体部分64中的部分中，布置天线元件66。

9. 发明申请

US20100085532A1 Display device and manufacturing method of the same 有权
标题翻译：显示装置及其制造方法相同
公开(公告)号：US20100085532A1
公开(公告)日：2010-04-08
申请号：US12591874
申请日：2009-12-03
申请人： Yoshiyuki Kiya , Kunihiko Watanabe , Toshikazu Horii , Takao Takano
发明人： Yoshiyuki Kiya , Kunihiko Watanabe , Toshikazu Horii , Takao Takano
IPC分类号： G02F1/13
CPC分类号： G02F1/136259
摘要： Even when a protective film, an insulation film or the like is present above a film to be corrected, only a defect of the film to be corrected which is arranged below such an upper-layer film is corrected without damaging the upper-layer film. In a display device forming a display region where a plurality of films including an insulation film, a semiconductor film and a conductive film are patterned in a given pattern and stacked on a substrate, at a point of time that at least one correction portion out of a correction portion which separates a short-circuit defect, a correction portion which connects an opening defect, a correction portion which removes a standard deviation defect, and a correction portion which separates a standard deviation defect of the pattern is corrected, at least one upper-layer film is present above a film to be corrected at the correction portion and the correction is applied to the film to be corrected while leaving the upper-layer film as it is.
摘要翻译：即使在要校正的膜上存在保护膜，绝缘膜等的情况下，也可以在不损害上层膜的情况下校正布置在该上层膜下方的被校正膜的缺陷。在形成显示区域的显示装置中，其中包括绝缘膜，半导体膜和导电膜的多个膜以给定图案被图案化并堆叠在基板上，在至少一个校正部分从校正分离短路缺陷的校正部分，连接开口缺陷的校正部分，去除标准偏差缺陷的校正部分和分离图案的标准偏差缺陷的校正部分被校正;至少一个上部在校正部分上存在要校正的膜上方的膜层，并且在离开上层膜的同时对要校正的膜进行校正。

10. 发明申请

US20090308632A1 Shielded conductor 审中-公开
标题翻译：屏蔽导体
公开(公告)号：US20090308632A1
公开(公告)日：2009-12-17
申请号：US11919252
申请日：2006-07-05
申请人： Kunihiko Watanabe
发明人： Kunihiko Watanabe
IPC分类号： H01B9/02
CPC分类号： H01B7/20 , H01R9/032
摘要： A shielded conductor A comprising a shield pipe 10 made of metal; a flexible shield member 20 which is made of metal and is connected to an end portion of the shield pipe 10; and an electric wire 30 which is shielded by being inserted into the shield pipe 10 and the flexible shield member 20, wherein the shield pipe 10 and the flexible shield member 20 are formed of a metal having a standard electrode potential difference of 1.50 V or less between the shield pipe and the flexible shield member. Preferably, the shield pipe 10 is made of stainless steel, copper or a copper alloy. Preferably, the flexible shield member 20 is made of stainless steel, copper or a copper alloy. Preferably, this shielded conductor A is used in a power circuit of an electric vehicle.
摘要翻译：一种屏蔽导体A，包括由金属制成的屏蔽管10; 柔性屏蔽件20，其由金属制成并连接到屏蔽管10的端部; 以及通过插入屏蔽管10和柔性屏蔽部件20而屏蔽的电线30，其中屏蔽管10和柔性屏蔽部件20由标准电极电位差为1.50V以下的金属形成在屏蔽管和柔性屏蔽构件之间。优选地，屏蔽管10由不锈钢，铜或铜合金制成。优选地，柔性屏蔽构件20由不锈钢，铜或铜合金制成。优选地，该屏蔽导体A用于电动车辆的电力回路中。

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