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1. 发明授权

US07274829B2 Measuring method and instrument comprising image sensor 有权
标题翻译：包括图像传感器的测量方法和仪器
公开(公告)号：US07274829B2
公开(公告)日：2007-09-25
申请号：US10415986
申请日：2001-11-09
申请人： Atsusi Wada , Kouji Egawa
发明人： Atsusi Wada , Kouji Egawa
IPC分类号： G06K9/40
CPC分类号： G01N21/5907 , G01J1/124 , G01J1/1626 , G01N21/274 , G01N2021/5949 , G01N2021/5957
摘要： A linearizing correction unit (104) carries out a linearizing correction process on the output of an image sensor (8) based upon linearizing correction data stored in a linearizing correction data holding unit (102), and a light-irregularity correction unit (108) carries out a light-irregularity correction process on the image sensor output that has been subjected to the linearizing correction process based upon light-irregularity correction data stored in a light-irregularity correction data holding unit (106). A refection factor calculation unit (110) calculates an integral value of the in-plane reflection factor of a test piece by using the output that has been subjected to the linearizing correction and light-irregularity correction with respect to pixel outputs of the image sensor (8) obtained when the test piece having in-plane density irregularities is measured. A quantifying unit (114) applies calibration curve data of a calibration-curve-data holding unit (112) to the integrated reflection factor obtained by the reflection factor calculation unit so that a sample density of the test piece is calculated.
摘要翻译：线性化校正单元（104）基于线性化校正数据保存单元（102）中存储的校正数据和光不规则校正单元（108），对图像传感器（8）的输出执行线性化校正处理，对已经经过线性化校正处理的图像传感器输出，基于存储在光不规则校正数据保持单元（106）中的光不规则校正数据执行光不规则校正处理。反射因子计算单元（110）通过使用对图像传感器的像素输出进行线性化校正和光不规则校正的输出来计算测试片的面内反射系数的积分值（测量具有面内密度不均匀的试验片时获得的图8所示的结果。量化单元（114）将校准曲线数据保持单元（112）的校准曲线数据应用于由反射因子计算单元获得的积分反射系数，从而计算出测试样本的样本密度。

2. 发明申请

US20080014610A1 Container for Nucleic Acid Extraction, Method of Cleaning Solid Matrix and Relevant Cleaning Mechanism, and Method of Purifying Nucleic Acid 审中-公开
标题翻译：用于核酸提取的容器，固体基质的清洗方法和相关的清洁机理以及纯化核酸的方法
公开(公告)号：US20080014610A1
公开(公告)日：2008-01-17
申请号：US11597970
申请日：2005-06-01
申请人： Tatsuo Kamata , Shinichi Ohta , Kouji Egawa
发明人： Tatsuo Kamata , Shinichi Ohta , Kouji Egawa
IPC分类号： C12N15/09 , C12M1/00 , G01N1/34 , C12M1/34
CPC分类号： B01L3/5085 , B01L3/502 , B01L2200/0631 , B01L2300/0609 , G01N1/34 , G01N1/405
摘要： The present invention relates to a nucleic acid extraction container (2) which includes a nucleic acid extraction element (20) for extracting a target nucleic acid from a sample and supporting the extracted nucleic acid, and a container main body formed as a separate member from the nucleic acid extraction element and having a having a housing vessel (27) for storing the nucleic acid extraction element (20). The nucleic acid extraction element (20) includes, for example, a solid matrix (23) for supporting the target nucleic acid, and a holding member (20) for holding the solid matrix (23). Preferably, the solid matrix (23) is held as tilted with respect to a vertical axis of the holding member (20).
摘要翻译：本发明涉及一种核酸提取容器（2），其包括用于从样品中提取目标核酸并支持所提取的核酸的核酸提取元件（20），以及形成为独立构件的容器主体所述核酸提取元件具有用于储存所述核酸提取元件（20）的容纳容器（27）。核酸提取元件（20）包括例如用于支撑靶核酸的固体基质（23）和用于保持固体基质（23）的保持构件（20）。优选地，固体基质（23）相对于保持构件（20）的垂直轴线保持倾斜。

3. 发明授权

US06455865B2 Test piece analyzing apparatus 有权
标题翻译：试片分析装置
公开(公告)号：US06455865B2
公开(公告)日：2002-09-24
申请号：US09845895
申请日：2001-04-30
申请人： Kouji Egawa
发明人： Kouji Egawa
IPC分类号： G01N2186
CPC分类号： G01N35/00029 , G01N1/2813 , G01N2035/00128
摘要： A test piece analyzing apparatus is provided which includes a releasably fixed absorbent member, a horizontally reciprocative pinching mechanism for simultaneously transferring a plurality of test pieces in a transfer direction, and an optical analyzing assembly provided with a primary illuminator and a secondary illuminator. The second illuminator serves to illuminate the bottom surface of the test piece.
摘要翻译：提供了一种试片分析装置，其包括可释放地固定的吸收构件，用于沿传送方向同时传送多个测试件的水平往复夹持机构，以及设置有主照明器和次照明器的光学分析组件。第二个照明器用于照亮测试片的底面。

4. 发明授权

US07110901B2 Correction method for sensor output 有权
标题翻译：传感器输出校正方法
公开(公告)号：US07110901B2
公开(公告)日：2006-09-19
申请号：US10415991
申请日：2001-11-09
申请人： Atsusi Wada , Kouji Egawa
发明人： Atsusi Wada , Kouji Egawa
IPC分类号： G01D18/00 , G11B7/00
CPC分类号： G01J1/1626 , G01J1/124 , G01N21/4738 , G01N21/59 , G01N2021/5949 , G01N2021/5957
摘要： Above a measuring object (2), an LEDs (4) for use in light irradiation and a CMOS area sensor (8) with an image-forming lens (6) interpolated in between are installed. In order to detect the quantity of light from the LEDs (4), a photodetector (10) is further placed. A personal computer (28) carries out a linearizing process which, upon variation of the quantity of light, corrects the output of the area sensor (8) so as to make the output from the area sensor (8) proportional to the output of the photodetector (10), and a light-irregularity correction process which, when a flat plate having even in-plane density is measured as the measuring object (2), corrects the resulting output of each pixel in the area sensor (8) that has been corrected by the linearizing process to have in-plane evenness. It becomes possible to achieve a convenient two-dimensional reflection factor measuring method which does not need any mechanical driving system.
摘要翻译：在测量对象（2）上方安装用于光照射的LED（4）和内置有图像形成透镜（6）的CMOS区域传感器（8）。为了检测来自LED（4）的光量，进一步放置光电检测器（10）。个人计算机（28）执行线性化处理，其在光量变化时校正区域传感器（8）的输出，以使区域传感器（8）的输出与光检测器（10）和光不均匀性校正处理，当测量具有平面密度的平板作为测量对象（2）时，校正已经具有的区域传感器（8）中的每个像素的所得输出通过线性化处理被校正为具有平面内均匀性。可以实现不需要任何机械驱动系统的方便的二维反射因子测量方法。

5. 发明申请

US20060140818A1 Tool for analyzing specimen 审中-公开
标题翻译：分析标本的工具
公开(公告)号：US20060140818A1
公开(公告)日：2006-06-29
申请号：US10545722
申请日：2004-10-19
申请人： Hisashi Sakamoto , Takeshi Matsuda , Kouji Egawa , Tetsuaki Saiji
发明人： Hisashi Sakamoto , Takeshi Matsuda , Kouji Egawa , Tetsuaki Saiji
IPC分类号： G01N31/22
CPC分类号： G01N33/523
摘要： The present invention provides a sample analysis tool that can provide a sufficient amount of information accurately and allows an analyzer to read out the information without using any special mechanism. In a sample analysis tool 1 including a reagent layer 11 and an information recording layer 12 formed on a substrate 13, the information recording layer is composed of one region or divided into a plurality of regions, and each region is colored with a single color. Information is recorded using at least one of a combination of color intensities over the plurality of regions and an area of each region.
摘要翻译：本发明提供一种能够准确地提供足够数量的信息并允许分析器读出信息而不使用任何特殊机制的样本分析工具。在包括形成在基板13上的试剂层11和信息记录层12的样本分析工具1中，信息记录层由一个区域或分成多个区域组成，并且每个区域用单一颜色着色。使用多个区域上的颜色强度的组合和每个区域的区域中的至少一个来记录信息。

6. 发明授权

US06337490B1 Test piece analyzing apparatus having an excessive portion removal 有权
标题翻译：具有过度部分去除的试件分析装置
公开(公告)号：US06337490B1
公开(公告)日：2002-01-08
申请号：US09364929
申请日：1999-08-02
申请人： Noriaki Furusato , Atsushi Murakami , Ken Kishimoto , Kouji Egawa
发明人： Noriaki Furusato , Atsushi Murakami , Ken Kishimoto , Kouji Egawa
IPC分类号： G01N2186
CPC分类号： G01N35/00029 , G01N1/2813 , G01N2035/00128
摘要： A test piece analyzing apparatus is provided which includes a releasably fixed absorbent member, a horizontally reciprocative pinching mechanism for simultaneously transferring a plurality of test pieces in a transfer direction, and an optical analyzing assembly provided with a primary illuminator and a secondary illuminator. The second illuminator serves to illuminate the bottom surface of the test piece.
摘要翻译：提供了一种试片分析装置，其包括可释放地固定的吸收构件，用于沿传送方向同时传送多个测试件的水平往复夹持机构，以及设置有主照明器和次照明器的光学分析组件。第二个照明器用于照亮测试片的底面。

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