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1. 发明申请

US20100323724A1 EXTRACORPOREAL BLOOD TREATMENT DEVICE AND METHOD FOR PREPARING BLOOD TREATMENT USING AN EXTRACORPOREAL BLOOD TREATMENT DEVICE 有权
标题翻译：超临界血液治疗装置及使用超临界血液治疗装置制备血液治疗的方法
公开(公告)号：US20100323724A1
公开(公告)日：2010-12-23
申请号：US12438775
申请日：2007-08-22
申请人： Klaus Balschat , Pascal Kopperschmidt , Reiner Spickermann
发明人： Klaus Balschat , Pascal Kopperschmidt , Reiner Spickermann
IPC分类号： H04W4/12 , H04B7/00
CPC分类号： A61M1/14 , A61M1/16 , A61M1/168 , A61M1/1682 , A61M1/34 , A61M1/3643 , A61M1/3644 , A61M2205/3553 , A61M2205/3584 , A61M2205/50 , A61M2205/502 , A61M2205/60 , A61M2205/70
摘要： The present invention relates to an extracorporeal blood treatment device comprising a treatment unit and a device for controlling the treatment unit for preparing and carrying out the blood treatment. The blood treatment device also comprises an internal communication unit for communicating with an external communication unit. In order to the prepare the device blood treatment, the patient sends an initiation code by means of an external communication unit to the internal communication device. Routines required for preparing the blood treatment are then started. One main advantage is that the patient, for example during home dialysis, does not need to be present when the device is preparing for dialysis and the dialysis preparation can be started when the patient thinks of returning home in time for the beginning of the preparation phase.
摘要翻译：本发明涉及一种体外血液处理装置，其包括处理单元和用于控制用于制备和进行血液处理的处理单元的装置。血液处理装置还包括用于与外部通信单元通信的内部通信单元。为了准备用于血液处理的装置，患者通过外部通信单元向内部通信装置发送启动代码。然后开始准备血液处理所需的程序。一个主要的优点是，例如在家庭透析期间，当设备正在进行透析时，患者不需要存在患者，并且当患者认为在准备阶段开始时及时回家时可以开始透析准备。

2. 发明授权

US08676512B2 Method and device for determining the transmembrane pressure in an extracorporeal blood treatment 有权
标题翻译：用于确定体外血液处理中跨膜压力的方法和装置
公开(公告)号：US08676512B2
公开(公告)日：2014-03-18
申请号：US12809791
申请日：2008-12-17
申请人： Klaus Balschat , Alfred Gagel , Michael Kulz , Reiner Spickermann
发明人： Klaus Balschat , Alfred Gagel , Michael Kulz , Reiner Spickermann
IPC分类号： A61M1/34 , G06F19/00 , G06F17/40
CPC分类号： A61M1/16 , A61M1/1601 , A61M1/34 , A61M1/3403 , A61M1/341 , A61M1/3413 , A61M1/36 , A61M2205/3331 , A61M2205/3334 , A61M2205/50
摘要： A method and device are provided for determining the transmembrane pressure during an extracorporeal blood treatment in which blood flows at a defined blood flow rate through an arterial blood conduit of an extracorporeal blood circuit into the inlet of a first chamber of a dialyzer, which is divided by a semipermeable membrane into the first chamber and a second chamber, and flows through a venous blood conduit from the outlet of the first chamber of the dialyzer, while dialysis liquid flows through a dialysis liquid supply conduit into the inlet of the second chamber of the dialyzer and flows through a dialaysis liquid discharge conduit from the outlet of the second chamber of the dialyzer. The method and the device for determining the transmembrane pressure are such that the pressure on the blood side and on the dialysis liquid side of the dialyzer is measured with relatively little technical outlay, specifically with fewer than four pressure sensors, and a preliminary uncorrected value is calculated for the transmembrane pressure and is thereafter corrected by a correction variable that is dependent on a variable correlating with the viscosity of the blood.
摘要翻译：提供了一种用于在体外血液处理期间确定跨膜压力的方法和装置，其中血液以限定的血液流量通过体外血液回路的动脉血管流入到透析器的第一腔室的入口中，该第一腔室被分开通过半透膜进入第一腔室和第二腔室，并且从透析器的第一腔室的出口流过静脉血液导管，同时透析液体流过透析液体供应管道进入第二腔室的入口透析器，并从透析器的第二腔室的出口流过拨号液体排出导管。用于确定跨膜压力的方法和装置使得透析器的血液侧和透析液体侧的压力以相对较少的技术支出来测量，特别是使用少于四个的压力传感器，初步未校正的值是计算跨膜压力，然后通过依赖于与血液粘度相关的变量的校正变量进行校正。

3. 发明授权

US08518258B2 Hemodialysis device, hemodiafiltration device, method for taking a sample in corresponding devices and sampling kit for use in corresponding devices and method 有权
标题翻译：血液透析装置，血液透析滤过装置，采集相应装置中的样品和用于相应装置和方法的取样试剂盒的方法
公开(公告)号：US08518258B2
公开(公告)日：2013-08-27
申请号：US12312040
申请日：2007-10-22
申请人： Klaus Balschat , Reiner Spickermann , Josef Winter
发明人： Klaus Balschat , Reiner Spickermann , Josef Winter
IPC分类号： C02F1/44 , A61M37/00
CPC分类号： A61M1/16 , A61M1/1605 , A61M1/1619 , A61M1/165 , A61M1/342 , A61M1/3441 , A61M1/3465 , A61M2205/50 , A61M2205/70
摘要： A hemodialysis machine or hemodiafiltration machine is provided that may be used directly for sampling for the connection to a hemodialyzer or for providing replacement fluid, as is required for regular microbiological testing. The machine does not require any additional components or any complex hygiene measures to prevent secondary contamination. By connecting an inventive sterile sampling set, samples can easily be taken. Closing elements and pumping mechanisms are controlled by a control unit as part of a sampling control program.
摘要翻译：提供血液透析机或血液透析滤过机，其可以直接用于取样以连接血液透析器或提供替代液体，如常规微生物测试所要求的。机器不需要任何额外的部件或任何复杂的卫生措施来防止二次污染。通过连接本发明的无菌取样装置，可以容易地取样。关闭元件和泵送机构由控制单元控制，作为采样控制程序的一部分。

4. 发明申请

US20130062265A1 MEDICAL TREATMENT ARRANGEMENT 有权
标题翻译：医疗治疗安排
公开(公告)号：US20130062265A1
公开(公告)日：2013-03-14
申请号：US13699110
申请日：2011-05-20
申请人： Klaus Balschat , Berthold Breitkopf , Klaus Sauer , Marcus Hartmann , Dejan Nikolic , Alexander Heide
发明人： Klaus Balschat , Berthold Breitkopf , Klaus Sauer , Marcus Hartmann , Dejan Nikolic , Alexander Heide
IPC分类号： A61M1/34 , A61M1/28
CPC分类号： A61M1/34 , A61M1/1656 , A61M1/1668 , A61M1/167 , A61M1/28 , A61M1/342 , A61M1/3455 , A61M2205/3569 , A61M2205/3592 , A61M2205/52 , A61M2205/6054 , A61M2205/6072 , A61M2209/084
摘要： The present invention relates to a medical treatment arrangement having at least three device parts, with the first device part being a device part which is not made for the treatment of a patient, with the second device part being made in conjunction with the third device part such that a treatment of a patient can be made with them, with the second device part being made movable relative to the first device part and relative to the third device part, and with provision furthermore being made that the first device part and the second device part and/or the second device part and the third device part being made such that energy and/or data can be unidirectionally or bidirectionally exchanged between them.
摘要翻译：本发明涉及具有至少三个装置部件的医疗处理装置，其中第一装置部分是不用于治疗患者的装置部分，其中第二装置部分与第三装置部分使得可以利用它们来对患者进行治疗，其中第二装置部分相对于第一装置部分和相对于第三装置部分可移动，并且还提供第一装置部分和第二装置部分和/或第二装置部分和第三装置部分被制成使得能量和/或数据可以在它们之间单向或双向交换。

5. 发明授权

US06595944B2 Dialysis machine and method of operating a dialysis machine 有权
公开(公告)号：US06595944B2
公开(公告)日：2003-07-22
申请号：US09882337
申请日：2001-06-15
申请人： Klaus Balschat , Michael Koch , Elmar Wolter
发明人： Klaus Balschat , Michael Koch , Elmar Wolter
IPC分类号： A61M3700
CPC分类号： B01F3/088 , A61M1/1607 , A61M1/1635 , A61M1/1654 , A61M1/1656 , A61M1/1668 , A61M2205/3396 , B01F15/00207 , B01F15/00344 , B01F15/0454 , B01F2215/0034
摘要： A machine and method for preparing dialysis fluid for a dialysis machine. Fresh water is mixed with one or more dialysis fluid concentrates. The mixture of water and concentrates is conveyed into an equalizing chamber by a proportioning unit at a predetermined flow rate independent of the dialysate flow rate. Metered addition of the concentrates is performed volumetrically and is monitored on the basis of the conductivity of the dialysis fluid, which is measured by conductivity sensors. Because the mixture of water and concentrates is always conveyed at the same flow rate, the composition of the dialysis fluid can be determined with a high accuracy and the proportioning can be performed accurately.

6. 发明授权

US08315654B2 Extracorporeal blood treatment device and method for preparing blood treatment using an extracorporeal blood treatment device 有权
标题翻译：体外血液处理装置及使用体外血液处理装置进行血液处理的方法
公开(公告)号：US08315654B2
公开(公告)日：2012-11-20
申请号：US12438775
申请日：2007-08-22
申请人： Klaus Balschat , Pascal Kopperschmidt , Reiner Spickermann
发明人： Klaus Balschat , Pascal Kopperschmidt , Reiner Spickermann
IPC分类号： H04W4/12
CPC分类号： A61M1/14 , A61M1/16 , A61M1/168 , A61M1/1682 , A61M1/34 , A61M1/3643 , A61M1/3644 , A61M2205/3553 , A61M2205/3584 , A61M2205/50 , A61M2205/502 , A61M2205/60 , A61M2205/70
摘要： The present invention relates to an extracorporeal blood treatment device comprising a treatment unit and a device for controlling the treatment unit for preparing and carrying out the blood treatment. The blood treatment device also comprises an internal communication unit for communicating with an external communication unit. In order to the prepare the device blood treatment, the patient sends an initiation code by means of an external communication unit to the internal communication device. Routines required for preparing the blood treatment are then started. One main advantage is that the patient, for example during home dialysis, does not need to be present when the device is preparing for dialysis and the dialysis preparation can be started when the patient thinks of returning home in time for the beginning of the preparation phase.
摘要翻译：本发明涉及一种体外血液处理装置，其包括处理单元和用于控制用于制备和进行血液处理的处理单元的装置。血液处理装置还包括用于与外部通信单元通信的内部通信单元。为了准备用于血液处理的装置，患者通过外部通信单元向内部通信装置发送启动代码。然后开始准备血液处理所需的程序。一个主要的优点是，例如在家庭透析期间，当设备准备透析时，患者不需要存在患者，并且当患者认为在准备阶段开始时及时回家时可以开始透析准备。

7. 发明申请

US20100130906A1 HEMODIALYSIS DEVICE, HEMODIAFILTRATION DEVICE, METHOD FOR TAKING A SAMPLE IN CORRESPONDING DEVICES AND SAMPLING KIT FOR USE IN CORRESPONDING DEVICES AND METHOD 有权
标题翻译：血液透析装置，HEMODIAFILTRATION装置，用于在相应装置中采样的样品和采样装置的方法和方法
公开(公告)号：US20100130906A1
公开(公告)日：2010-05-27
申请号：US12312040
申请日：2007-10-22
申请人： Klaus Balschat , Reiner Spickermann
发明人： Klaus Balschat , Reiner Spickermann
IPC分类号： A61M1/34
CPC分类号： A61M1/16 , A61M1/1605 , A61M1/1619 , A61M1/165 , A61M1/342 , A61M1/3441 , A61M1/3465 , A61M2205/50 , A61M2205/70
摘要： The invention relates to the field of equipment for renal replacement therapy. It is based on the observation that connections (14, 15, 101) already present in a hemodialysis machine or hemodiafiltration machine (10) may also be used directly for sampling for the connection to a hemodialyzer or for providing replacement fluid, as is required for regular microbiological testing. The invention does not require any additional components on the equipment or any complex hygiene measures to prevent secondary contamination. By connecting an inventive sterile sampling set, samples can easily be taken. On the equipment end, one need only to program the control unit (26) to implement the inventive method by means of corresponding control of the closing means (20, 21, 103) and the pumping mechanisms (17, 18) as part of a sampling control program.
摘要翻译：本发明涉及用于肾替代治疗的设备领域。基于以下观察，已经存在于血液透析机或血液透析滤器（10）中的连接（14,15,101）也可以直接用于取样连接到血液透析器或用于提供置换液体，如定期进行微生物检测。本发明不需要设备上的任何附加部件或任何复杂的卫生措施来防止二次污染。通过连接本发明的无菌取样装置，可以容易地取样。在设备端，仅需要对控制单元（26）进行编程，以通过对闭合装置（20,21,103）和泵机构（17,18）的相应控制来实现本发明的方法，作为抽样控制程序。

8. 发明授权

US09511182B2 Medical treatment arrangement 有权
标题翻译：医疗安排
公开(公告)号：US09511182B2
公开(公告)日：2016-12-06
申请号：US13699110
申请日：2011-05-20
申请人： Klaus Balschat , Berthold Breitkopf , Klaus Sauer , Marcus Hartmann , Dejan Nikolic , Alexander Heide
发明人： Klaus Balschat , Berthold Breitkopf , Klaus Sauer , Marcus Hartmann , Dejan Nikolic , Alexander Heide
IPC分类号： A61M1/14 , A61M1/34 , A61M1/16 , A61M1/28
CPC分类号： A61M1/34 , A61M1/1656 , A61M1/1668 , A61M1/167 , A61M1/28 , A61M1/342 , A61M1/3455 , A61M2205/3569 , A61M2205/3592 , A61M2205/52 , A61M2205/6054 , A61M2205/6072 , A61M2209/084
摘要： The present invention relates to a medical treatment arrangement having at least three device parts, with the first device part being a device part which is not made for the treatment of a patient, with the second device part being made in conjunction with the third device part such that a treatment of a patient can be made with them, with the second device part being made movable relative to the first device part and relative to the third device part, and with provision furthermore being made that the first device part and the second device part and/or the second device part and the third device part being made such that energy and/or data can be unidirectionally or bidirectionally exchanged between them.
摘要翻译：本发明涉及具有至少三个装置部件的医疗处理装置，其中第一装置部分是不用于治疗患者的装置部分，其中第二装置部分与第三装置部分使得可以利用它们来对患者进行治疗，其中第二装置部分相对于第一装置部分和相对于第三装置部分可移动，并且还提供第一装置部分和第二装置部分和/或第二装置部分和第三装置部分被制成使得能量和/或数据可以在它们之间单向或双向交换。

9. 发明授权

US08104348B2 Method and device for monitoring a flowing liquid for the presence of air 有权
标题翻译：用于监测流动液体以存在空气的方法和装置
公开(公告)号：US08104348B2
公开(公告)日：2012-01-31
申请号：US11921624
申请日：2006-04-15
申请人： Klaus Balschat , Tobias Fritsche , Alfred Gagel , Steffen Kirchner , Hans-Joachim Muench , Olaf Nicholas , Jochen Schneider , Reiner Spickermann , Santer Zur Host-Meyer
发明人： Klaus Balschat , Tobias Fritsche , Alfred Gagel , Steffen Kirchner , Hans-Joachim Muench , Olaf Nicholas , Jochen Schneider , Reiner Spickermann , Santer Zur Host-Meyer
IPC分类号： G01H3/12
CPC分类号： G01N29/032 , A61M1/3626 , G01N2291/02433 , G01N2291/02466 , G01N2291/02854
摘要： The present invention relates to a method and a device for monitoring a flowing medium, in particular the blood flowing in an extracorporeal blood circulation, for the presence of air, in particular micro-bubbles. A sequence of signal pulses or a continuous signal is injected into the flowing medium, and the signal pulses or continuous signal leaving the flowing medium are received. To detect micro-bubbles, a signal pattern that is characteristic of the variation over time of the received signal pulses or the continuous signal in a predetermined period of time is extracted from the signal received. The characteristic signal pattern is compared with one or more characteristic reference patterns, and the presence of air bubbles is determined if the characteristic signal pattern deviates from the characteristic reference pattern by a predetermined amount. Statistical characteristic variables, in particular the variance, are preferably determined from the signal patterns and compared with one another.
摘要翻译：本发明涉及用于监测流动介质，特别是在体外血液循环中流动的血液，用于存在空气，特别是微气泡的方法和装置。信号脉冲序列或连续信号被注入到流动介质中，并且接收离开流动介质的信号脉冲或连续信号。为了检测微气泡，从接收到的信号中提取出在接收到的信号脉冲或连续信号随时间变化的特征的信号模式。将特征信号图案与一个或多个特征参考图案进行比较，并且如果特征信号图案偏离特征参考图案预定量，则确定气泡的存在。统计特征变量，特别是方差，优选地根据信号图案确定并相互比较。

10. 发明申请

US20100280761A1 METHOD AND DEVICE FOR DETERMINING THE TRANSMEMBRANE PRESSURE IN AN EXTRACORPOREAL BLOOD TREATMENT 有权
标题翻译：用于确定超临界血液治疗中的转移压力的方法和装置
公开(公告)号：US20100280761A1
公开(公告)日：2010-11-04
申请号：US12809791
申请日：2008-12-17
申请人： Klaus Balschat , Alfred Gagel , Michael Külz , Rainer Spickermann
发明人： Klaus Balschat , Alfred Gagel , Michael Külz , Rainer Spickermann
IPC分类号： G06F19/00 , A61M1/16 , G01L7/00
CPC分类号： A61M1/16 , A61M1/1601 , A61M1/34 , A61M1/3403 , A61M1/341 , A61M1/3413 , A61M1/36 , A61M2205/3331 , A61M2205/3334 , A61M2205/50
摘要： A method and device are provided for determining the transmembrane pressure during an extracorporeal blood treatment in which blood flows at a defined blood flow rate through an arterial blood conduit of an extracorporeal blood circuit into the inlet of a first chamber of a dialyzer, which is divided by a semipermeable membrane into the first chamber and a second chamber, and flows through a venous blood conduit from the outlet of the first chamber of the dialyzer, while dialysis liquid flows through a dialysis liquid supply conduit into the inlet of the second chamber of the dialyzer and flows through a dialaysis liquid discharge conduit from the outlet of the second chamber of the dialyzer. The method and the device for determining the transmembrane pressure are such that the pressure on the blood side and on the dialysis liquid side of the dialyzer is measured with relatively little technical outlay, specifically with fewer than four pressure sensors, and a preliminary uncorrected value is calculated for the transmembrane pressure and is thereafter corrected by a correction variable that is dependent on a variable correlating with the viscosity of the blood.
摘要翻译：提供了一种用于在体外血液处理期间确定跨膜压力的方法和装置，其中血液以限定的血液流量通过体外血液回路的动脉血管流入到透析器的第一腔室的入口中，该第一腔室被分开通过半透膜进入第一腔室和第二腔室，并且从透析器的第一腔室的出口流过静脉血液导管，同时透析液体流过透析液体供应管道进入第二腔室的入口透析器，并从透析器的第二腔室的出口流过拨号液体排出导管。用于确定跨膜压力的方法和装置使得透析器的血液侧和透析液体侧的压力以相对较少的技术支出来测量，特别是使用少于四个的压力传感器，初步未校正的值是计算跨膜压力，然后通过依赖于与血液粘度相关的变量的校正变量进行校正。

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