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1. 发明授权

US6008893A Reversible-flow conduit system 有权
标题翻译：可逆流量管道系统
公开(公告)号：US6008893A
公开(公告)日：1999-12-28
申请号：US273615
申请日：1999-03-22
申请人： Hakan Roos , Kjell Magnusson
发明人： Hakan Roos , Kjell Magnusson
IPC分类号： G01N33/543 , G01N35/08 , G01N35/10 , G01N21/01
CPC分类号： G01N35/085
摘要： Systems and methods for reversibly and controllably flowing a first and second fluid adjacent to one or more discrete sensing surfaces of a biosensor are disclosed herein. The systems utilize a flow-cell conduit adapted to flow the first and second fluids in either a first or second flow direction and in a manner such that the first and second fluids separately contact the one or more discrete sensing surfaces of the biosensor. The flow-cell conduit is operatively connected to both a two-fluid conduit and a single-fluid conduit via a valveless juncture. The system also comprises a selector valve for reversing the flow direction of the fluid within the flow-cell conduit.
摘要翻译：本文公开了用于可逆地和可控地流动邻近生物传感器的一个或多个离散感测表面的第一和第二流体的系统和方法。该系统利用流动池导管，其适于使第一和第二流体沿第一或第二流动方向流动，并且使得第一和第二流体分别接触生物传感器的一个或多个离散的感测表面。流动池导管经由无阀接头可操作地连接到双流体导管和单流体导管两者。该系统还包括用于反转流动池导管内的流体的流动方向的选择阀。

2. 发明授权

US07015043B2 Flow cell method 失效
公开(公告)号：US07015043B2
公开(公告)日：2006-03-21
申请号：US10184024
申请日：2002-06-26
申请人： Håkan Roos , Kjell Magnusson , Mattias Tidare
发明人： Håkan Roos , Kjell Magnusson , Mattias Tidare
IPC分类号： G01N1/10 , G01N21/05
CPC分类号： G01N21/05 , Y10T436/118339 , Y10T436/2575
摘要： A method of operating an analytical flow cell device comprising an elongate flow cell having a first end and a second end, at least two ports at the first end and at least one port at the second end, comprises introducing a laminar flow of a first fluid at the first end of the flow cell, and a laminar counter flow of a second fluid at the second end. Each fluid flow is discharged at the first end or the second end, and the position of the interface between the first and second fluids in the longitudinal direction of the flow cell is adjusted by controlling the relative flow rates of the first and second fluids. Also disclosed are a method of analyzing a fluid sample for an analyte, a method of sensitizing a sensing surface, and a method of contacting a sensing surface with a test fluid.

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