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1. 发明授权

US06660032B2 Expandable coil endoluminal prosthesis 有权
标题翻译：可扩展线圈腔内假体
公开(公告)号：US06660032B2
公开(公告)日：2003-12-09
申请号：US09834145
申请日：2001-04-12
申请人： Katherine J. Klumb , Thomas J. Fogarty , Kirti P. Kamdar , Bradley B. Hill
发明人： Katherine J. Klumb , Thomas J. Fogarty , Kirti P. Kamdar , Bradley B. Hill
IPC分类号： A61F206
CPC分类号： A61F2/958 , A61F2/07 , A61F2/88 , A61F2/954 , A61F2002/065 , A61F2002/067 , A61F2002/075 , A61F2002/9511 , A61F2002/9517 , A61F2220/005 , A61F2220/0058 , A61F2220/0075 , A61F2250/0018 , A61F2250/0039
摘要： A coiled stent (196) has a coiled stent body with a main body portion (106) and end portions (108). The end portions may be substantially less stiff than the body portion to help prevent tissue trauma. A graft material (124) may be used to cover at least the main body portion to create a coiled stent graft (122) in which adjacent turns (128) have gaps defined therebetween to create a generally helical gap (130). The coiled stent may have side elements (10) separated by connector elements (112) and be placeable in a contracted, reduced diameter state and in a relaxed, expanded diameter state. The connector elements are preferably generally parallel to the stent axis when placed in the contracted, reduced-diameter state, typically tightly wrapped around a placement catheter (136).
摘要翻译：螺旋支架（196）具有带有主体部分（106）和端部（108）的盘绕支架主体。端部可以比主体部分基本上更加硬，以帮助防止组织创伤。移植材料（124）可用于至少覆盖主体部分以形成卷绕的支架移植物（122），其中相邻的匝（128）之间具有间隙以形成大致螺旋的间隙（130）。卷绕的支架可以具有由连接器元件（112）分开的侧部元件（10），并且可以以收缩的直径减小的状态并且处于松弛的扩径的状态。当连接器元件处于收缩的缩径状态时，优选地大致平行于支架轴线，通常紧密地缠绕在放置导管（136）周围。

2. 发明授权

US6102907A Apparatus and device for use therein and method for ablation of tissue 失效
标题翻译：用于其中的装置和装置及其组织消融方法
公开(公告)号：US6102907A
公开(公告)日：2000-08-15
申请号：US912273
申请日：1997-08-15
申请人： Rick T. Smethers , James A. Filice , Kirti P. Kamdar , Peter H. Muller
发明人： Rick T. Smethers , James A. Filice , Kirti P. Kamdar , Peter H. Muller
IPC分类号： A61B17/24 , A61B18/12 , A61B18/14 , A61B18/18
CPC分类号： A61B18/1477 , A61B2018/00755 , A61B2018/00821 , A61B2018/00875 , A61B2018/1253 , A61B2018/1475
摘要： A device for the ablation of tissue for use with the human hand and a radio frequency power supply and controller providing a source of radio frequency energy and a control for controlling the application of radio frequency energy to the device. The device includes a handle sized so that is adapted to be grasped by the human hand and has proximal and distal extremities. A needle formed of a conducting material has proximal and distal extremities. The proximal extremity of the needle is mounted on the distal extremity of the handle so that it is insulated from the handle. Conductors are carried by the handle and are connected to the needle and extend from the handle and are coupled to the radio frequency power supply and controller for supplying radio frequency energy to the needle. A temperature sensor is carried by the handle and is adapted to be coupled to the radio frequency power supply and controller for sensing the application of radio frequency energy to the tissue for controlling the application of radio frequency energy to the needle.
摘要翻译：用于消除用于人手的组织的装置和提供射频能量源的射频电源和控制器以及用于控制将射频能量应用于该装置的控制。该装置包括尺寸适于被人的手抓住并具有近端和远端的手柄。由导电材料形成的针头具有近端和远端。针的近端被安装在手柄的远端上，使得其与手柄绝缘。导体由手柄承载并连接到针上并从手柄延伸并且耦合到射频电源和控制器以向针提供射频能量。温度传感器由手柄承载，并且适于耦合到射频电源和控制器，用于感测向组织施加射频能量，以控制向针施加射频能量。

3. 发明授权

US06409652B1 Device and method for delivery of uniform and controlled radiation dose to blood vessels 失效
标题翻译：用于将均匀和受控的辐射剂量递送到血管的装置和方法
公开(公告)号：US06409652B1
公开(公告)日：2002-06-25
申请号：US09665729
申请日：2000-09-20
申请人： Kirti P. Kamdar , Majid Leonard Riaziat , William K. Wheeler , Raisa Pavlyuchkova
发明人： Kirti P. Kamdar , Majid Leonard Riaziat , William K. Wheeler , Raisa Pavlyuchkova
IPC分类号： A61N500
CPC分类号： A61N5/1002 , A61M2025/1047 , A61N2005/1003
摘要： The present invention provides a device, system and method for uniformly delivering a radiation dose over the surface area of a stenosed vessel during or after a percutaneous transluminal angioplasty procedure. A helical balloon is inflated in the region to be treated, preferably in contact with the vessel wall, and a radiation source is drawn through the helical coils of the balloon to provide a uniform dosage. Alternatively, the helical balloon is disposed within a cylindrical balloon and the helical balloon containing a radiation source with at least one coil is drawn through the cylindrical balloon.
摘要翻译：本发明提供了一种用于在经皮腔内血管成形术过程中或之后均匀地递送在狭窄血管的表面区域上的辐射剂量的装置，系统和方法。在待处理的区域中，优选地与血管壁接触，螺旋状的气囊被膨胀，并且辐射源被吸入气球的螺旋线圈以提供均匀的剂量。或者，螺旋形气球设置在圆柱形球囊内，并且包含具有至少一个线圈的辐射源的螺旋形气球被抽吸通过圆柱形球囊。

4. 发明授权

US06238430B1 Catheter assembly with controlled release endoluminal prosthesis and method for placing 失效
标题翻译：具有控制释放腔内假体的导管组件和放置方法
公开(公告)号：US06238430B1
公开(公告)日：2001-05-29
申请号：US09400952
申请日：1999-09-22
申请人： Katherine J. Klumb , Thomas J. Fogarty , Kirti P. Kamdar , Bradley B. Hill
发明人： Katherine J. Klumb , Thomas J. Fogarty , Kirti P. Kamdar , Bradley B. Hill
IPC分类号： A61F206
CPC分类号： A61F2/958 , A61F2/07 , A61F2/88 , A61F2/954 , A61F2002/065 , A61F2002/067 , A61F2002/075 , A61F2002/9511 , A61F2002/9517 , A61F2220/005 , A61F2220/0058 , A61F2220/0075 , A61F2250/0018 , A61F2250/0039
摘要： A catheter assembly includes a coiled endoluminal prosthesis (122, 190, 198) and a catheter (136) having at least first and second telescoping shafts (138, 140, 142). The prosthesis is releasably engaged to the distal ends (144, 146, 148) of the telescoping shafts. The prosthesis is capable of assuming a second, expanded diameter state from a first, reduced diameter state. The length and number of turns (128) of the coiled prosthesis can be changed by the relative translation and rotation of the shafts. The catheter assembly is especially useful for placing a coiled stent graft (122), in which one turn (132, 134) of the prosthesis has a greater pitch than the adjacent turns, at the intersection (184) of a bifurcation within a blood vessel (182). Remotely viewable marker elements (188, 190, 191, 192, 193, 195, 197) may be used and include a marker element (193, 190A, 197) configured to indicate orientation as well as axial position of the prosthesis. The ends of the prosthesis may be substantially less stiff than the remainder of the prosthesis and/or shaped to help prevent tissue trauma.
摘要翻译：导管组件包括螺旋的腔内假体（122,190,198）和具有至少第一和第二伸缩轴（138,140,142）的导管（136）。假体可释放地接合到伸缩轴的远端（144,146,148）。该假体能够从第一直径减小状态来呈现第二扩张直径状态。线圈假体的长度和匝数（128）可以通过轴的相对平移和旋转来改变。所述导管组件特别适用于放置卷绕的支架移植物（122），其中所述假体的一匝（132,134）在相对于匝内的分叉处的距离（184）处具有比相邻匝更大的间距（182）。远程可见的标记元件（188,190,191,192,193,195,197）可以被使用并且包括构造成指示假体的取向以及轴向位置的标记元件（193,190A，197）。假体的端部可能比假体的其余部分基本上较硬，和/或成形为有助于防止组织损伤。

5. 发明授权

US06645237B2 Expandable coiled endoluminal prosthesis 有权
标题翻译：可扩展卷曲腔内假体
公开(公告)号：US06645237B2
公开(公告)日：2003-11-11
申请号：US09400955
申请日：1999-09-22
申请人： Katherine J. Klumb , Thomas J. Fogarty , Kirti P. Kamdar , Bradley B. Hill
发明人： Katherine J. Klumb , Thomas J. Fogarty , Kirti P. Kamdar , Bradley B. Hill
IPC分类号： A61F206
CPC分类号： A61F2/958 , A61F2/07 , A61F2/88 , A61F2/954 , A61F2002/065 , A61F2002/067 , A61F2002/075 , A61F2002/9511 , A61F2002/9517 , A61F2220/005 , A61F2220/0058 , A61F2220/0075 , A61F2250/0018 , A61F2250/0039
摘要： A coiled stent (196) has a coiled stent body with a main body portion (106) and end portions (108). The end portions may be substantially less stiff than the body portion to help prevent tissue trauma. A graft material (124) may be used to cover at least the main body portion to create a coiled stent graft (122) in which adjacent turns (128) have gaps defined therebetween to create a generally helical gap (130). The coiled stent may have side elements (10) separated by connector elements (112) and be placeable in a contracted, reduced diameter state and in a relaxed, expanded diameter state. The connector elements are preferably generally parallel to the stent axis when placed in the contracted, reduced-diameter state, typically tightly wrapped around a placement catheter (136).
摘要翻译：螺旋支架（196）具有带有主体部分（106）和端部（108）的盘绕支架主体。端部可以比主体部分基本上更加硬，以帮助防止组织创伤。移植材料（124）可用于至少覆盖主体部分以形成卷绕的支架移植物（122），其中相邻的匝（128）之间具有间隙以形成大致螺旋的间隙（130）。卷绕的支架可以具有由连接器元件（112）分开的侧部元件（10），并且可以以收缩的直径减小的状态并且处于松弛的扩径的状态。当连接器元件处于收缩的缩径状态时，优选地大致平行于支架轴线，通常紧密地缠绕在放置导管（136）周围。

6. 发明授权

US06488700B2 Endoluminal prosthesis placing method 失效
标题翻译：腔内假体放置法
公开(公告)号：US06488700B2
公开(公告)日：2002-12-03
申请号：US09826204
申请日：2001-04-04
申请人： Katherine J. Klumb , Thomas J. Fogarty , Kirti P. Kamdar , Bradley B. Hill
发明人： Katherine J. Klumb , Thomas J. Fogarty , Kirti P. Kamdar , Bradley B. Hill
IPC分类号： A61F206
CPC分类号： A61F2/958 , A61F2/07 , A61F2/88 , A61F2/954 , A61F2002/065 , A61F2002/067 , A61F2002/075 , A61F2002/9511 , A61F2220/005 , A61F2220/0058 , A61F2250/0018 , A61F2250/0039
摘要： A catheter assembly includes a coiled endoluminal prosthesis (122, 190, 198) and a catheter (136) having at least first and second telescoping shafts (138, 140, 142). The prosthesis is releasably engaged to the distal ends (144, 146, 148) of the telescoping shafts. The prosthesis is capable of assuming a second, expanded diameter state from a first, reduced diameter state. The length and number of turns (128) of the coiled prosthesis can be changed by the relative translation and rotation of the shafts. The catheter assembly is especially useful for placing a coiled stent graft (122), in which one turn (132, 134) of the prosthesis has a greater pitch than the adjacent turns, at the intersection (184) of a bifurcation within a blood vessel (182). Remotely viewable marker elements (188, 190, 191, 192, 193, 195, 197) may be used and include a marker element (193, 190A, 197) configured to indicate orientation as well as axial position of the prosthesis. The ends of the prosthesis may be substantially less stiff than the remainder of the prosthesis and/or shaped to help prevent tissue trauma.
摘要翻译：导管组件包括螺旋的腔内假体（122,190,198）和具有至少第一和第二伸缩轴（138,140,142）的导管（136）。假体可释放地接合到伸缩轴的远端（144,146,148）。该假体能够从第一直径减小状态来呈现第二扩张直径状态。线圈假体的长度和匝数（128）可以通过轴的相对平移和旋转来改变。所述导管组件特别适用于放置卷绕的支架移植物（122），其中所述假体的一匝（132,134）在相对于匝内的分叉处的距离（184）处具有比相邻匝更大的间距（182）。远程可见的标记元件（188,190,191,192,193,195,197）可以被使用并且包括构造成指示假体的取向以及轴向位置的标记元件（193,190A，197）。假体的端部可能比假体的其余部分基本上较硬，和/或成形为有助于防止组织损伤。

7. 发明授权

US06248122B1 Catheter with controlled release endoluminal prosthesis 失效
标题翻译：导管与控制释放内腔假体
公开(公告)号：US06248122B1
公开(公告)日：2001-06-19
申请号：US09258542
申请日：1999-02-26
申请人： Katherine J. Klumb , Thomas J. Fogarty , Kirti P. Kamdar
发明人： Katherine J. Klumb , Thomas J. Fogarty , Kirti P. Kamdar
IPC分类号： A61M2902
CPC分类号： A61F2/958 , A61F2/07 , A61F2/88 , A61F2/954 , A61F2002/065 , A61F2002/067 , A61F2002/075 , A61F2002/9511 , A61F2002/9517 , A61F2220/005 , A61F2220/0058 , A61F2220/0075 , A61F2250/0018 , A61F2250/0039
摘要： A catheter (4) includes a hollow catheter shaft (18), an inflatable balloon (36) surrounding the catheter shaft distal portion, and an expandable endoluminal prosthesis, such as a stent graft (38, 40), surrounding the balloon. The stent is typically a coiled stent having distal ends (58, 48) slidably housed within stent end holders (56, 50) on the catheter shaft. The first stent end is released from its holder by inflating the balloon. The second stent end is selectively released from its holder by other than inflating the balloon, typically by a push wire (30) pushing the second stent end out of its holder. A sheath (8) is moveable between a first position surrounding the stent and a second position spaced-apart from the stent. The stent is prevented from assuming its expanded-diameter state by (1) the engagement of the stent ends with the catheter shaft through the stent end holders, and (2) the sheath being in its first position during the introducing step. The stent may be a straight stent (3 8) or a bifurcated stent (38D).
摘要翻译：导管（4）包括中空的导管轴（18），围绕导管轴远端部分的可膨胀气囊（36）和围绕气囊的可扩张的腔内假体，例如支架移植物（38,40）。支架通常是具有可滑动地容纳在导管轴上的支架端部保持器（56,50）内的远端（58,48）的盘绕支架。通过使气囊膨胀，第一个支架端从其支架释放。通常通过将第二支架端部推出其保持器的推动线（30）来使第二支架端部从其保持器选择性地释放，除了使气囊膨胀。护套（8）可以在围绕支架的第一位置和与支架间隔开的第二位置之间移动。通过（1）支架端部与导管轴通过支架端部保持器接合，防止支架呈现其扩径状态，以及（2）在引入步骤期间护套处于其第一位置。支架可以是直支架（38）或分叉支架（38D）。

8. 发明授权

US06921414B2 Endoluminal prosthesis and tissue separation condition treatment method 失效
标题翻译：腔内假体和组织分离条件治疗方法
公开(公告)号：US06921414B2
公开(公告)日：2005-07-26
申请号：US10308574
申请日：2002-12-03
申请人： Katherine J. Klumb , Thomas J. Fogarty , Kirti P. Kamdar , Bradley B. Hill
发明人： Katherine J. Klumb , Thomas J. Fogarty , Kirti P. Kamdar , Bradley B. Hill
IPC分类号： A61F2/06 , A61F2/84 , A61F2/88
CPC分类号： A61F2/88 , A61F2/91 , A61F2/95 , A61F2002/9511
摘要： An endoluminal prosthesis includes a coiled body and a graft material covering at least part of the coiled body to create a coiled stent graft. The average stent graft diameter to turns width ratio may be about 0.8 to 1 to about 2.4 to 1 when expanded.
摘要翻译：腔内假体包括螺旋体和覆盖线圈体的至少一部分的移植材料，以产生盘绕的支架移植物。当扩张时，平均支架移植物直径与匝间宽度比可以为约0.8至1至约2.4至1。

9. 发明授权

US06572648B1 Endoluminal prosthesis and tissue separation condition treatment method 失效
公开(公告)号：US06572648B1
公开(公告)日：2003-06-03
申请号：US09608281
申请日：2000-06-30
申请人： Katherine J. Klumb , Thomas J. Fogarty , Kirti P. Kamdar , Bradley B. Hill
发明人： Katherine J. Klumb , Thomas J. Fogarty , Kirti P. Kamdar , Bradley B. Hill
IPC分类号： A61F206
CPC分类号： A61F2/88 , A61F2/91 , A61F2/95 , A61F2002/9511
摘要： An endoluminal prosthesis includes a coiled body and a graft material covering at least part of the coiled body to create a coiled stent graft. The average stent graft diameter to turns width ratio may be about 0.8 to 1 to about 2.4 to 1 when expanded.

10. 发明授权

US6165173A Memory for regulating device utilization and behavior 失效
标题翻译：用于调节设备利用率和行为的内存
公开(公告)号：US6165173A
公开(公告)日：2000-12-26
申请号：US167222
申请日：1998-10-06
申请人： Kirti P. Kamdar , Robin Bek
发明人： Kirti P. Kamdar , Robin Bek
IPC分类号： A61B18/00 , A61B18/12 , A61B18/14
CPC分类号： A61B18/14 , A61B18/1206 , A61B18/1402 , A61B2017/00482 , A61B2018/00178 , A61B2018/00642 , A61B2018/00702 , A61B2018/0075 , A61B2018/00779 , A61B2018/00791 , A61B2018/00827 , A61B2018/00875 , A61B2018/00892 , A61B2018/00988 , A61B2018/1273 , Y10S128/923
摘要： A cell necrosis apparatus is described. The cell necrosis apparatus includes an identification and usage device capable of performing an encrypted handshake protocol with an energy source. The identification and usage device is capable of identifying the cell necrosis apparatus, to prevent the use of unauthorized devices with the energy source, as well as controlling and causing a record to be made of a usage of the cell necrosis apparatus.
摘要翻译：描述细胞坏死装置。细胞坏死装置包括能够用能量来执行加密的握手协议的识别和使用装置。识别和使用装置能够识别细胞坏死装置，以防止使用具有能量源的未经授权的装置，以及控制并引起对细胞坏死装置的使用的记录。

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