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1. 发明授权

US07820289B2 Inorganic-organic melt-extruded hybrid yarns and fibrous composite medical devices thereof 有权
标题翻译：无机 - 有机熔融挤出混合纱线及其纤维复合医疗装置
公开(公告)号：US07820289B2
公开(公告)日：2010-10-26
申请号：US12456826
申请日：2009-06-23
申请人： Shalaby W Shalaby , Kimberly A Carpenter , Kenneth W Clinkscales
发明人： Shalaby W Shalaby , Kimberly A Carpenter , Kenneth W Clinkscales
IPC分类号： D02G3/00 , B32B25/02
CPC分类号： D01F1/10 , A61F2/0063 , A61L17/005 , A61L17/10 , A61L17/145 , A61L31/127 , A61L31/128 , A61L31/148 , A61L31/16 , A61L31/18 , A61L2300/622 , A61L2300/624 , D01F6/62 , D01F6/625 , D01F6/64 , D01F6/86 , D02G3/04 , D02G3/38 , D02G3/448 , Y10T428/249938 , Y10T428/29 , Y10T428/2913 , Y10T428/2915 , Y10T428/2931 , Y10T428/298 , Y10T442/105 , Y10T442/3146 , Y10T442/3154 , Y10T442/3171 , Y10T442/3301 , Y10T442/425 , Y10T442/431 , Y10T442/438 , Y10T442/444
摘要： Composite fibrous constructs are made of combinations of inorganic-organic hybrid monofilament or multifilament yarns containing at least 6 weight percent of inorganic micro-/nanoparticles and organic monofilament or multifilament yarn with typical examples of the hybrid yarn matrix made of absorbable or non-absorbable thermoplastic polymers and final constructs being in the form of knitted or woven meshes and braided ligatures intended to perform under specific mechanically, biologically, and/or radiologically related functions.
摘要翻译：复合纤维构造物由含有至少6重量％的无机微/纳米颗粒和有机单丝或多丝纱的无机 - 有机杂化单丝或复丝纱的组合制成，具有由可吸收或不可吸收的热塑性塑料制成的混合纱线基质的典型实例聚合物和最终构造物是针织或梭织网格和编织结扎的形式，旨在在特定的机械，生物学和/或放射学相关功能下进行。

2. 发明授权

US07632765B2 Inorganic-organic melt-extruded hybrid yarns and fibrous composite medical devices thereof 有权
公开(公告)号：US07632765B2
公开(公告)日：2009-12-15
申请号：US11880993
申请日：2007-07-25
申请人： Shalaby W Shalaby , Kenneth W Clinkscales , Kimberly A. Carpenter
发明人： Shalaby W Shalaby , Kenneth W Clinkscales , Kimberly A. Carpenter
IPC分类号： D03D15/00 , B32B5/08 , D04B21/14
CPC分类号： D01F1/10 , A61F2/0063 , A61L17/005 , A61L17/10 , A61L17/145 , A61L31/127 , A61L31/128 , A61L31/148 , A61L31/16 , A61L31/18 , A61L2300/622 , A61L2300/624 , D01F6/62 , D01F6/625 , D01F6/64 , D01F6/86 , D02G3/04 , D02G3/38 , D02G3/448 , Y10T428/249938 , Y10T428/29 , Y10T428/2913 , Y10T428/2915 , Y10T428/2931 , Y10T428/298 , Y10T442/105 , Y10T442/3146 , Y10T442/3154 , Y10T442/3171 , Y10T442/3301 , Y10T442/425 , Y10T442/431 , Y10T442/438 , Y10T442/444
摘要： Composite fibrous constructs are made of combinations of inorganic-organic hybrid monofilament or multifilament yarns containing at least 6 weight percent of inorganic micro-/nanoparticles and organic monofilament or multifilament yarn with typical examples of the hybrid yarn matrix made of absorbable or non-absorbable thermoplastic polymers and final constructs being in the form of knitted or woven meshes and braided ligatures intended to perform under specific mechanically, biologically, and/or radiologically related functions.

3. 发明申请

US20090287228A1 Inorganic-organic melt-extruded hybrid yarns and fibrous composite medical devices thereof 有权
标题翻译：无机 - 有机熔融挤出混合纱线及其纤维复合医疗装置
公开(公告)号：US20090287228A1
公开(公告)日：2009-11-19
申请号：US12456826
申请日：2009-06-23
申请人： Shalaby W Shalaby , Kimberly A Carpenter , Kenneth W Clinkscales
发明人： Shalaby W Shalaby , Kimberly A Carpenter , Kenneth W Clinkscales
IPC分类号： A61B17/03 , A61K9/70 , A61L17/00
CPC分类号： D01F1/10 , A61F2/0063 , A61L17/005 , A61L17/10 , A61L17/145 , A61L31/127 , A61L31/128 , A61L31/148 , A61L31/16 , A61L31/18 , A61L2300/622 , A61L2300/624 , D01F6/62 , D01F6/625 , D01F6/64 , D01F6/86 , D02G3/04 , D02G3/38 , D02G3/448 , Y10T428/249938 , Y10T428/29 , Y10T428/2913 , Y10T428/2915 , Y10T428/2931 , Y10T428/298 , Y10T442/105 , Y10T442/3146 , Y10T442/3154 , Y10T442/3171 , Y10T442/3301 , Y10T442/425 , Y10T442/431 , Y10T442/438 , Y10T442/444
摘要： Composite fibrous constructs are made of combinations of inorganic-organic hybrid monofilament or multifilament yarns containing at least 6 weight percent of inorganic micro-/nanoparticles and organic monofilament or multifilament yarn with typical examples of the hybrid yarn matrix made of absorbable or non-absorbable thermoplastic polymers and final constructs being in the form of knitted or woven meshes and braided ligatures intended to perform under specific mechanically, biologically, and/or radiologically related functions.
摘要翻译：复合纤维构造物由含有至少6重量％的无机微/纳米颗粒和有机单丝或多丝纱的无机 - 有机杂化单丝或复丝纱的组合制成，具有由可吸收或不可吸收的热塑性塑料制成的混合纱线基质的典型实例聚合物和最终构造物是针织或梭织网格和编织结扎的形式，旨在在特定的机械，生物学和/或放射学相关功能下进行。

4. 发明申请

US20080183208A1 Inorganic-organic melt-extruded hybrid yarns and fibrous composite medical devices thereof 有权
标题翻译：无机 - 有机熔融挤出混合纱线及其纤维复合医疗装置
公开(公告)号：US20080183208A1
公开(公告)日：2008-07-31
申请号：US11880993
申请日：2007-07-25
申请人： Shalaby W. Shalaby , Kenneth W. Clinkscales , Kimberly A. Carpenter
发明人： Shalaby W. Shalaby , Kenneth W. Clinkscales , Kimberly A. Carpenter
IPC分类号： A61L17/00 , D02G3/04 , D03D15/00
CPC分类号： D01F1/10 , A61F2/0063 , A61L17/005 , A61L17/10 , A61L17/145 , A61L31/127 , A61L31/128 , A61L31/148 , A61L31/16 , A61L31/18 , A61L2300/622 , A61L2300/624 , D01F6/62 , D01F6/625 , D01F6/64 , D01F6/86 , D02G3/04 , D02G3/38 , D02G3/448 , Y10T428/249938 , Y10T428/29 , Y10T428/2913 , Y10T428/2915 , Y10T428/2931 , Y10T428/298 , Y10T442/105 , Y10T442/3146 , Y10T442/3154 , Y10T442/3171 , Y10T442/3301 , Y10T442/425 , Y10T442/431 , Y10T442/438 , Y10T442/444
摘要： Composite fibrous constructs are made of combinations of inorganic-organic hybrid monofilament or multifilament yarns containing at least 6 weight percent of inorganic micro-/nanoparticles and organic monofilament or multifilament yarn with typical examples of the hybrid yarn matrix made of absorbable or non-absorbable thermoplastic polymers and final constructs being in the form of knitted or woven meshes and braided ligatures intended to perform under specific mechanically, biologically, and/or radiologically related functions.
摘要翻译：复合纤维构造物由含有至少6重量％的无机微/纳米颗粒和有机单丝或多丝纱的无机 - 有机杂化单丝或复丝纱的组合制成，具有由可吸收或不可吸收的热塑性塑料制成的混合纱线基质的典型实例聚合物和最终构造物是针织或梭织网格和编织结扎的形式，旨在在特定的机械，生物学和/或放射学相关功能下进行。

5. 发明授权

US09011439B2 Selectively absorbable/biodegradable, fibrous composite constructs and applications thereof 有权
标题翻译：选择性吸收/可生物降解的纤维复合结构及其应用
公开(公告)号：US09011439B2
公开(公告)日：2015-04-21
申请号：US11983321
申请日：2007-11-08
申请人： Shalaby W. Shalaby , Shawn Peniston , Kimberly A. Carpenter
发明人： Shalaby W. Shalaby , Shawn Peniston , Kimberly A. Carpenter
IPC分类号： A61B17/04 , A61B17/56 , A61L27/48 , A61L27/58 , C08L23/06
CPC分类号： A61L27/48 , A61L27/54 , A61L27/58 , C08L23/06 , C08L2203/12 , C08L67/04
摘要： A family of selectively absorbable/biodegradable, fibrous composite constructs includes different combinations of biostable and absorbable/biodegradable yarns assembled as initially interdependent, load-bearing components, transitioning to exhibit independent functional properties during in vivo end-use. The family of constructs consists of two groups, one group is made of fiber-reinforced composites of high compliance, absorbable matrices of segmented polyaxial copolyesters reinforced with multifilament yarn constructs, which are combinations of ultrahigh molecular weight polyethylene fibers and at least one absorbable/biodegradable fiber selected from silk fibers and multifilament yarns made from linear segmented, l-lactide copolyesters and poly (3-hydroxyalkanoates, are useful in orthopedic, maxillofacial, urological, vascular, hernial repair and tissue engineering applications. The second group is made of coated and uncoated, warp-knitted mesh constructs for use in hernial, vascular, and urological tissue repair and tissue engineering.
摘要翻译：一系列可选择性吸收/可生物降解的纤维复合材料构造包括生物稳定和可吸收/可生物降解的纱线的不同组合，其组装为最初相互依赖的承载组分，在体内最终用途中转变为显示独立的功能特性。构建体组由两组组成，一组由高柔顺性的纤维增强复合材料制成，由多丝纱构造物增强的分段多轴共聚酯的可吸收基质，其是超高分子量聚乙烯纤维和至少一种可吸收/可生物降解的组合纤维选自由线性分段的丙交酯共聚酯和聚（3-羟基链烷酸酯）制成的丝纤维和复丝纱，可用于矫形，颌面，泌尿，血管，疝修补和组织工程应用中，第二组由涂层和用于疝，血管和泌尿组织修复和组织工程的无涂层，经编网眼构造物。

6. 发明申请

US20080119848A1 Selectively absorbable/biodegradable, fibrous composite constructs and applications thereof 有权
标题翻译：选择性吸收/可生物降解的纤维复合结构及其应用
公开(公告)号：US20080119848A1
公开(公告)日：2008-05-22
申请号：US11983321
申请日：2007-11-08
申请人： Shalaby W. Shalaby , Shawn Peniston , Kimberly A. Carpenter
发明人： Shalaby W. Shalaby , Shawn Peniston , Kimberly A. Carpenter
IPC分类号： A61B17/04 , A61B17/56
CPC分类号： A61L27/48 , A61L27/54 , A61L27/58 , C08L23/06 , C08L2203/12 , C08L67/04
摘要： A family of selectively absorbable/biodegradable, fibrous composite constructs includes different combinations of biostable and absorbable/biodegradable yarns assembled as initially interdependent, load-bearing components, transitioning to exhibit independent functional properties during in vivo end-use. The family of constructs consists of two groups, one group is made of fiber-reinforced composites of high compliance, absorbable matrices of segmented polyaxial copolyesters reinforced with multifilament yarn constructs, which are combinations of ultrahigh molecular weight polyethylene fibers and at least one absorbable/biodegradable fiber selected from silk fibers and multifilament yarns made from linear segmented, l-lactide copolyesters and poly (3-hydroxyalkanoates, are useful in orthopedic, maxillofacial, urological, vascular, hernial repair and tissue engineering applications. The second group is made of coated and uncoated, warp-knitted mesh constructs for use in hernial, vascular, and urological tissue repair and tissue engineering.
摘要翻译：一系列可选择性吸收/可生物降解的纤维复合材料构造包括生物稳定和可吸收/可生物降解的纱线的不同组合，其组装为最初相互依赖的承载组分，在体内最终用途中转变为显示独立的功能特性。构建体组由两组组成，一组由高柔顺性的纤维增强复合材料制成，由多丝纱构造物增强的分段多轴共聚酯的可吸收基质，其是超高分子量聚乙烯纤维和至少一种可吸收/可生物降解的组合纤维选自由线性分段的丙交酯共聚酯和聚（3-羟基链烷酸酯）制成的丝纤维和复丝纱，可用于矫形，颌面，泌尿，血管，疝修补和组织工程应用中，第二组由涂层和用于疝，血管和泌尿组织修复和组织工程的无涂层，经编网眼构造物。

7. 发明授权

US07465489B2 Inorganic-organic melted-extruded hybrid filaments and medical applications thereof 有权
标题翻译：无机 - 有机熔融挤出杂化丝及其医疗应用
公开(公告)号：US07465489B2
公开(公告)日：2008-12-16
申请号：US11599691
申请日：2006-11-15
申请人： Shalaby W Shalaby , Kenneth W Clinkscales , Kimberly A. Carpenter
发明人： Shalaby W Shalaby , Kenneth W Clinkscales , Kimberly A. Carpenter
IPC分类号： B32B25/02 , C04B32/33
CPC分类号： D01F1/10 , A61L17/10 , A61L31/128 , A61L31/18 , Y10T428/249938 , Y10T428/2913 , Y10T428/2927 , Y10T428/298
摘要： This invention deals with a family of inorganic-organic hybrid, melt-extruded filaments having variable cross-sectional geometry with a cross-sectional area ranging between 100 μ2 and 4 mm2, wherein the inorganic component comprises at least 10 weight percent of the total system and is present as dispersed micro-/nanoparticles in an organic absorbable or non-absorbable matrix representing no more than 90 weight percent. Hybrid filaments are particularly useful for the production of absorbable/disintegratable coil components of an absorbable/disintegratable endoureteral stent and radiopaque surgical markers or sutures.
摘要翻译：本发明涉及一种无机 - 有机杂化物，具有横截面积可变的横截面几何形状的熔体挤出长丝，横截面积在100平方毫米至4平方毫米之间，其中无机成分占总体系的至少10重量％并且作为分散的微/纳米颗粒存在于不超过90重量％的有机可吸收或不可吸收的基质中。混合细丝特别可用于生产可吸收/可分解的输尿管支架和不透射线外科标记物或缝合线的可吸收/可分解的线圈组件。

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