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1. 发明申请

US20100032061A1 METHOD FOR MANUFACTURING A Ni-BASED ALLOY ARTICLE AND PRODUCT THEREFROM 审中-公开
标题翻译：制造镍基合金制品及其制品的方法
公开(公告)号：US20100032061A1
公开(公告)日：2010-02-11
申请号：US12538385
申请日：2009-08-10
申请人： Hiroyuki Anada , Shoji Kinomura , Noriaki Hirohata , Manabu Kanzaki , Kazuyuki Kitamura
发明人： Hiroyuki Anada , Shoji Kinomura , Noriaki Hirohata , Manabu Kanzaki , Kazuyuki Kitamura
IPC分类号： C23C8/10
CPC分类号： C23C8/10 , C23C8/16
摘要： A method for manufacturing a Ni-based alloy article which elutes little Ni even when used in a high-temperature water environment for a long period comprises heating the Ni-based alloy in a carbon dioxide-containing atmosphere for a set period of time at an elevated temperature to form an oxide film comprising chromium oxide on a surface thereof. Using carbon dioxide as an oxidizing gas produces an oxide film of generally uniform thickness along a length of the article being treated so that resistance to nickel elution is more uniform over the entire article.
摘要翻译：即使长时间在高温水环境中使用也可以洗脱少量Ni的Ni系合金制品的制造方法包括在含二氧化碳的气氛中将Ni系合金在一定时间内加热升高温度以在其表面上形成包含氧化铬的氧化物膜。使用二氧化碳作为氧化气体，沿着待处理的制品的长度产生大致均匀厚度的氧化膜，使得在整个制品上耐镍洗脱更均匀。

2. 发明授权

US5726148A Method of treating metabolic bone diseases with an IL-1 receptor 失效
标题翻译：用IL-1受体治疗代谢性骨疾病的方法
公开(公告)号：US5726148A
公开(公告)日：1998-03-10
申请号：US487646
申请日：1995-06-07
申请人： Masakazu Katoh , Kazuyuki Kitamura
发明人： Masakazu Katoh , Kazuyuki Kitamura
IPC分类号： A61K38/00 , A61K38/17 , A61P19/10 , A61P43/00 , A61K45/05
CPC分类号： A61K38/1793
摘要： A method of treating metabolic bone diseases comprising using a pharmaceutical composition which comprises as an active ingredient IL-1 receptor, a soluble fragment consisting of an extracellular domain of IL-1R or a fragment thereof derived from mammals. The composition has a bone resorption inhibiting activity and is useful for the therapy and prophylaxis of metabolic bone diseases.
摘要翻译：一种治疗代谢性骨疾病的方法，包括使用包含作为活性成分IL-1受体的由IL-1R的细胞外结构域或其衍生自哺乳动物的片段组成的可溶性片段的药物组合物。该组合物具有骨吸收抑制活性，可用于治疗和预防代谢性骨疾病。

3. 发明授权

US5169861A Benzothiophene compounds 失效
标题翻译：苯并噻吩化合物
公开(公告)号：US5169861A
公开(公告)日：1992-12-08
申请号：US645433
申请日：1991-01-24
申请人： Tameo Iwasaki , Masaki Sugiura , Yuzo Matsuoka , Mamoru Matsumoto , Kazuyuki Kitamura
发明人： Tameo Iwasaki , Masaki Sugiura , Yuzo Matsuoka , Mamoru Matsumoto , Kazuyuki Kitamura
IPC分类号： C07D493/04 , C07D495/04
CPC分类号： C07D493/04 , C07D495/04 , Y10S514/893 , Y10S514/894
摘要： A novel biphenyl derivative of the formula: ##STR1## wherein Ring A is a substituted or unsubstituted sulfur-containing or oxygen-containing heteromonocyclic ring; Ring B is a ring of the formula: ##STR2## each of R.sup.1 to R.sup.3 is hydrogen atom, a halogen atom or a lower alkoxy group, or R.sup.1 is hydrogen atom, and R.sup.2 and R.sup.3 are combined together to form a lower alkylenedioxy group; R.sup.4 is a lower alkyl group which may have a substituent selected from a lower alkoxy group and a lower alkoxycarbonyl group; Y is methylene group or carbonyl group, and a pharmaceutically acceptable salt thereof are disclosed. Said derivative and a pharmaceutically acceptable salt thereof are useful as a therapeutic or prophylactic agent for hepatic diseases.
摘要翻译：一种下式的新型联苯衍生物：其中环A是取代或未取代的含硫或含氧杂环; 环B是下式的环：R1至R3各自为氢原子，卤素原子或低级烷氧基，或R1为氢原子，R2和R3组合在一起形成低级亚烷基二氧基; R4是可以具有选自低级烷氧基和低级烷氧基羰基的取代基的低级烷基; Y是亚甲基或羰基，并且其药学上可接受的盐被公开。所述衍生物及其药学上可接受的盐可用作肝脏疾病的治疗或预防剂。

4. 发明申请

US20090123775A1 Method for producing Cr containing nickel-base alloy tube and Cr containing nickel-base alloy tube 审中-公开
标题翻译：含Cr的镍基合金管和含镍的镍基合金管的生产方法
公开(公告)号：US20090123775A1
公开(公告)日：2009-05-14
申请号：US12285644
申请日：2008-10-10
申请人： Manabu Kanzaki , Kazuyuki Kitamura , Noriaki Hirohata
发明人： Manabu Kanzaki , Kazuyuki Kitamura , Noriaki Hirohata
IPC分类号： B29D23/00 , B05D7/22 , B32B1/08
CPC分类号： C23C8/16 , C22C19/05 , C22F1/10 , F22B37/002 , F22B37/04 , Y10T428/12292
摘要： To form a chromium oxide film on the inner surface of a Cr containing nickel-base alloy tube inexpensively and uniformly, the Cr containing nickel-base alloy tube is heated in atmospheric gas of carbon dioxide gas and non-oxidation gas to form an oxide film consisting of chromium oxide having a thickness of 0.2 to 1.5 μm on the inner surface of the Cr containing nickel-base alloy tube. The atmospheric gas may contain oxygen gas of 5 vol % or less and/or water vapor of 7.5 vol % or less.
摘要翻译：为了廉价且均匀地在含Cr的镍基合金管的内表面上形成氧化铬膜，将含Cr的镍基合金管在二氧化碳气体和非氧化气体的大气中加热，形成氧化膜在含Cr的镍基合金管的内表面上由厚度为0.2-1.5μm的氧化铬组成。气氛气体可以含有5体积％以下的氧气和/或7.5体积％以下的水蒸汽。

5. 发明授权

US06702906B2 Ni-base heat resistant alloy and welded joint thereof 有权
标题翻译：镍基耐热合金及其焊接接头
公开(公告)号：US06702906B2
公开(公告)日：2004-03-09
申请号：US10192607
申请日：2002-07-11
申请人： Kazuhiro Ogawa , Kazuyuki Kitamura , Hirokazu Okada , Yoshitaka Nishiyama
发明人： Kazuhiro Ogawa , Kazuyuki Kitamura , Hirokazu Okada , Yoshitaka Nishiyama
IPC分类号： C22C1905
CPC分类号： C22C19/056 , B23K35/304 , C22C19/055
摘要： A Ni-base heat resistant alloy excellent in weldability and strength at elevated temperatures and suited for use in manufacturing cracking furnace tubes and reformer furnace tubes to be used in ethylene plants as well as a welded joint therefor is provided. The alloy of the invention is a Ni-base heat-resistant alloy, which comprises C: not more than 0.1%, Si: not more than 2%, Mn: not more than 2%, P: not more than 0.025%, S: not more than 0.005%, N: not more than 0.04%, Cr: 10 to 30%, Al: 2.1 to less than 4.5%, and Mo: 2.5 to 15% or W: 2.5 to 9% or Mo and W: 2.5 to 15% in total, and satisfies the relation (1) given below: (104Si+1980P+1980S+9Al+15Ti+11Nb+1.8W+11600B)≦{1.1(240−20000S−1900P−30Al−10Ti−9W+17000B) (1) In the welded joint of the invention, both of the base metal and weld metal are made of the alloy having the above composition, and the ST value of the weld metal as calculated according to the following formula (2) or (3) is larger by not less than 3 than the ST value of the base metal: in the case of Ti≦4C; ST=Mo+1.5W+100Ti (2) in the case of Ti>4C; ST=Mo+1.5W+400C (3).
摘要翻译：提供了一种耐高温焊接性和强度优异的镍基耐热合金，适用于制造用于乙烯装置的裂解炉管和重整炉管以及其焊接接头。本发明的合金是Ni基耐热合金，其包含C：不大于0.1％，Si：不大于2％，Mn：不大于2％，P：不大于0.025％，S ：不大于0.005％，N：不大于0.04％，Cr：10〜30％，Al：2.1〜小于4.5％，Mo：2.5〜15％或W：2.5〜9％或Mo和W： 2.5〜15％，满足下述关系式（1）：在本发明的焊接接头中，基体金属和焊接金属均由具有上述成分的合金构成，焊接的ST值根据下式（2）或（3）计算的金属比贱金属的ST值大3以上：

6. 发明授权

US5879799A Elastic polyurethane fibers and process for production thereof 失效
标题翻译：弹性聚氨酯纤维及其生产方法
公开(公告)号：US5879799A
公开(公告)日：1999-03-09
申请号：US981217
申请日：1997-12-19
申请人： Akihiko Yosizato , Kazuyuki Kitamura
发明人： Akihiko Yosizato , Kazuyuki Kitamura
IPC分类号： C08G18/10 , C08G18/48 , D01F6/70 , D02G3/00 , C08G18/30
CPC分类号： D01F6/70 , C08G18/10 , C08G18/4854 , Y10T428/2913
摘要： A polyurethane elastic fiber made from a polyurethane obtained from a copolymerized polyalkyleneether diol composed of different alkyleneethers containing 2-10 carbon atoms; the polyurethane comprises a urethane portion having a number average molecular weight of 6000-9500 and a urea portion having a number average molecular weight of 650-950. The polyurethane elastic fiber has improved elastic functions such as high elongation at break (elongation at break is 500%, or more), low modulus (300% modulus is 0.20 g/d, or less), excellent low temperature characteristics, and heat resistance; and, therefore, creation of highly excellent converted goods is made possible.The elastic fiber can be produced at a higher productivity by spinning the polyurethane prepared by reacting a copolymerized polyalkyleneether diol composed of different alkyleneethers containing 2-10 carbon atoms and 4,4'-diphenylmethane diisocyanate to form a fully isocyanate terminated prepolymer for forming the said urethane portion followed by an additional loading of said diisocyanate and reacting a bifunctional diamine such as ethylenediamine to form said urea portion.
摘要翻译： PCT No.PCT / JP96 / 01728 Sec。 371 1997年12月19日第 102（e）1997年12月19日PCT PCT 1996年6月21日PCT公布。公开号WO97 / 00982 日期1997年1月9日由由含有2-10个碳原子的不同亚烷基醚组成的共聚聚亚烷基二醇二醇得到的聚氨酯弹性纤维; 聚氨酯包括数均分子量为6000-9500的氨基甲酸酯部分和数均分子量为650-950的脲部分。聚氨酯弹性纤维具有改善的弹性功能，例如高断裂伸长率（断裂伸长率为500％以上），低模量（300％模量为0.20g / d以下），优异的低温特性和耐热性 ; 因此，可以实现高度优异的转换货物的创建。可以通过使由含有2-10个碳原子的不同亚烷基醚组成的共聚聚亚烷基醚二醇与4,4'-二苯基甲烷二异氰酸酯反应制得的聚氨酯纺丝，形成完全异氰酸酯封端的预聚物，从而以更高的生产率生产弹性纤维，形成所述氨基甲酸酯部分，然后另外加载所述二异氰酸酯，并使双官能二胺如乙二胺反应形成所述脲部分。

7. 发明授权

US5604263A Treating osteoporosis with humulones 失效
标题翻译：用肱骨头骨治疗骨质疏松症
公开(公告)号：US5604263A
公开(公告)日：1997-02-18
申请号：US420728
申请日：1995-04-10
申请人： Hiroyasu Tobe , Kazuyuki Kitamura
发明人： Hiroyasu Tobe , Kazuyuki Kitamura
IPC分类号： A61K31/12
CPC分类号： A61K31/12
摘要： A pharmaceutical composition for treating osteoporosis which comprises as an active ingredient an effective amount of one or more compounds selected from the-group comprising humulone, cohumulone, adhumulone, isohumulone, isocohumulone and isoadhumulone in combination with a pharmaceutically acceptable carrier or excipient. Humulone, cohumulone, adhumulone are the compounds belonging to .alpha. acids which are an ingredient extracted from hops, whilst isohumulone, isocohumulone and isoadhumulone are the compounds belonging to iso .alpha. acid derivatives which are isomers of .alpha. acids.The above described compounds have a bone resorption inhibiting activity and are useful for treating osteoporosis.
摘要翻译：一种用于治疗骨质疏松症的药物组合物，其包含有效量的一种或多种选自包含葎草酮，共聚葎草酮，异葎草酮，异葎草酮，异葎草酮和异葎草酮的化合物与药学上可接受的载体或赋形剂的组合。葎草酮，共葎草酮，异葎草酮是属于从啤酒花提取的成分的α-酸的化合物，而异葎草酮，异葎草酮和异葎草酮是属于α酸异构体的异α酸衍生物的化合物。上述化合物具有骨吸收抑制活性，可用于治疗骨质疏松症。

8. 发明授权

US4083894A Polyamide prepared in the presence of sulfopolyester 失效
标题翻译：在磺基聚酯存在下制备聚酰胺
公开(公告)号：US4083894A
公开(公告)日：1978-04-11
申请号：US536695
申请日：1974-12-26
申请人： Tetsuhiro Kusunose , Masataka Ideka , Kazuyuki Kitamura , Tsukasa Shima , Hiroshi Henmi
发明人： Tetsuhiro Kusunose , Masataka Ideka , Kazuyuki Kitamura , Tsukasa Shima , Hiroshi Henmi
IPC分类号： C08G69/00 , C08G63/00 , C08G63/688 , C08G69/04 , C08G69/36 , C08G69/42 , D01F6/90 , C08L77/00
CPC分类号： C08G69/36
摘要： A process for preparing polyamides which comprises polymerizing a polyamide-forming compound selected from the group consisting of .omega.-aminocarboxylic acids, .omega.-lactams and an equimolar mixture of a diamine and a dicarboxylic acid and modifying the polyamide formed in the polymerization by incorporating at least one compound of the formula (I) ##STR1## wherein M represents an alkali metal or an alkaline earth metal; n is an integer of 2 to 4; and m is an integer of 2 or more; before, during or after the polymerization.
摘要翻译：一种制备聚酰胺的方法，其包括聚合选自ω-氨基羧酸，ω-内酰胺和二胺和二羧酸的等摩尔混合物的聚酰胺形成化合物，并且通过至少并入至少引入聚合中形成的聚酰胺一种式（I）的化合物其中M表示碱金属或碱土金属; n为2〜4的整数， m为2以上的整数，在聚合之前，期间或之后。

9. 发明授权

US07037390B2 Method of heat treatment for Ni-base alloy tube 有权
标题翻译：镍基合金管热处理方法
公开(公告)号：US07037390B2
公开(公告)日：2006-05-02
申请号：US10681117
申请日：2003-10-09
申请人： Osamu Miyahara , Toshihiro Imoto , Hiroyuki Anada , Kazuyuki Kitamura
发明人： Osamu Miyahara , Toshihiro Imoto , Hiroyuki Anada , Kazuyuki Kitamura
IPC分类号： C22C1/10
CPC分类号： C22C19/058 , C21D1/74 , C21D9/08 , C22F1/02 , C22F1/10 , C23C8/10 , C23C8/16
摘要： A method of heat treatment for an efficient forming of two-layered oxide film on the inside surface of a Ni-base alloy tube. The oxide film suppresses the Ni release in a high-temperature water environment.At least two gas supplying devices are provided on the outlet side of a continuous heat treatment furnace; or one gas supplying device is provided respectively on the outlet side and the inlet side thereof. The tube is put into the furnace while supplying an atmospheric gas into the tube from the front end of the tube moving direction with one of these gas supplying devices and a gas introducing pipe, which is arranged inside the furnace, and this tube is maintained at 650 to 1200° C. for 1 to 1200 minutes. The atmospheric gas consists of hydrogen or a mixture of hydrogen and argon, whose dew point is in a range of from −60° C. to +20° C. After the front end of the Ni-base alloy tube reaches the outlet side of the furnace, the supply of atmospheric gas into the tube is switched to the supply from other gas supplying device. The operations are repeated.
摘要翻译：一种用于在Ni基合金管的内表面上有效形成双层氧化膜的热处理方法。该氧化物膜在高温水环境中抑制Ni释放。在连续热处理炉的出口侧设置至少两个供气装置; 或者在其出口侧和入口侧分别设置一个气体供给装置。将管放入炉中，同时从管移动方向的前端向气体供给装置和气体导入管中的一个供给大气气体，并将该管保持在炉内 650〜1200℃1〜1200分钟。气氛气体由氢气或氢气和氩气的混合物组成，其露点在-60℃至+ 20℃的范围内。在Ni基合金管的前端到达出口侧炉子中，将大气气体供应到管中被切换到来自其他气体供应装置的供应。重复操作。

10. 发明授权

US5733897A Imidobisphosphoric acids, and use therefor 失效
标题翻译：咪唑磷酸，并用于此
公开(公告)号：US5733897A
公开(公告)日：1998-03-31
申请号：US525104
申请日：1995-09-08
申请人： Christoph Naumann , Katsuhiro Yoshikawa , Kazuyuki Kitamura , Mizuho Inazu
发明人： Christoph Naumann , Katsuhiro Yoshikawa , Kazuyuki Kitamura , Mizuho Inazu
IPC分类号： A61K31/66 , A61P3/00 , A61P19/10 , A61P43/00 , C07F9/22 , C07F9/24 , C07F9/58 , C07F9/6533
CPC分类号： C07F9/222 , C07F9/2495 , C07F9/588 , C07F9/6533
摘要： Imidobisphosphoric acids, process for their preparation, and use thereof. There are described compounds of the formula I ##STR1## in which R.sup.1 is (C.sub.1 -C.sub.10)-alkyl, (C.sub.1 -C.sub.8)-alkanoyl, (C.sub.6 -C.sub.10)-aryl or Het, each of which can be substituted by halogen, --OH, --NH.sub.2, --NH--CO--R.sup.7, --O--CO--R.sup.7 and --N--(R.sup.8).sub.2 where R.sup.7 =(C.sub.1 -C.sub.6)-alkyl and R.sup.8, independently of one another, is hydrogen or (C.sub.1 -C.sub.4)-alkyl or in which R.sup.1 is the radical of the formula II ##STR2## in which n is an integer from 3 to 10, m is zero to 3, R.sup.6, independently of one another, is (C.sub.1 -C.sub.6)-alkyl which is optionally substituted by halogen or --NH--CO--R.sup.7, where R.sup.7 =(C.sub.1 -C.sub.6)-alkyl, and X is absent or is (C.sub.1 -C.sub.10)-alkyl, and R.sup.2, R.sup.3, R.sup.4 or R.sup.5, independently of one another, are hydrogen, (C.sub.1 -C.sub.5)-alkyl, lithium, sodium, potassium or Si(R), where R=(C.sub.1 -C.sub.5) -alkyl, and their physiologically tolerable salts, a process for preparation of these compounds of the formula I and their use as pharmaceuticals in the prophylaxis and treatment of osteoporosis and hypercalcemia.
摘要翻译：二异氰酸，其制备方法及其用途。描述了式I（I）的化合物，其中R 1是（C 1 -C 10） - 烷基，（C 1 -C 8） - 烷酰基，（C 6 -C 10） - 芳基或Het，其各自可以被取代通过卤素，-OH，-NH 2，-NH-CO-R 7，-O-CO-R 7和-N-（R 8）2，其中R 7 =（C 1 -C 6） - 烷基和R 8彼此独立地是氢或（C 1 -C 4） - 烷基，或其中R 1是式II的基团，其中n是3至10的整数，m是0-3，R6彼此独立地是任选被卤素或-NH-CO-R 7取代的（C 1 -C 6） - 烷基，其中R 7 =（C 1 -C 6） - 烷基，且X不存在或为（C 1 -C 10） - 烷基，且R 2，R 3 ，R 4或R 5彼此独立地为氢，（C 1 -C 5） - 烷基，锂，钠，钾或Si（R），其中R =（C 1 -C 5） - 烷基及其生理上可耐受的盐，制备这些式I化合物的方法及其作为药物用于预防和治疗骨质疏松症和高钙血症的用途。

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