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    • 3. 发明申请
    • Method of preparing immunoregulatory dendritic cells and the use thereof
    • 免疫调节性树突状细胞的制备方法及其用途
    • US20040235162A1
    • 2004-11-25
    • US10740834
    • 2003-12-22
    • KIRIN BEER KABUSHIKI KAISHAKatsuaki SATO
    • Katsuaki Sato
    • C12N005/08
    • C12N5/064A61K2035/122A61K2035/124C12N2501/15C12N2501/23
    • This invention provides: a therapeutic agent for graft rejection, graft-versus-host disease, autoimmune disease, allergic disease, or other diseases comprising dendritic cells (DCs) induced under culture conditions comprising both IL-10 and TGF-null or DCs prepared by adding inflammatory stimulation (e.g., TNF-null or LPS) to the aforementioned DCs and, if necessary, an antigen associated with a target disease; a method of inducing human immunoregulatory dendritic cells by culturing human dendritic cells or their precursor cells in vitro with cytokines comprising at least IL-10 and TGF-null; human immunoregulatory dendritic cells obtained by such method; and a pharmaceutical composition comprising such human immunoregulatory dendritic cells.
    • 本发明提供:用于移植排斥,移植物抗宿主病,自身免疫性疾病,过敏性疾病或包括在包含IL-10和TGF-β或DC的培养条件下诱导的树突细胞(DC)的其它疾病的治疗剂,所述培养条件由 向上述DC加入炎症刺激(如TNF-α或LPS),如有必要,加入与目标疾病相关的抗原; 通过在体外用包含至少IL-10和TGF-β的细胞因子培养人树突状细胞或其前体细胞来诱导人免疫调节性树突状细胞的方法; 通过这种方法获得的人免疫调节性树突状细胞; 和包含这种人免疫调节性树突状细胞的药物组合物。
    • 10. 发明授权
    • Embossed carrier tape and embossed carrier taping method
    • 压纹载带和压花载带胶带方法
    • US6105783A
    • 2000-08-22
    • US280861
    • 1999-03-30
    • Katsuaki Sato
    • Katsuaki Sato
    • B65B15/04B65D73/02H05K13/00
    • H05K13/0084B65D73/02
    • In order to solve the aforementioned problems, the present invention provides an embossed carrier tape comprising a plurality of device holes defined in an embossed carrier tape material at predetermined intervals so as to hold electronic devices therein, and protective ribs provided between the adjacent device holes respectively. Another invention provides a taping method for an embossed carrier tape with electronic devices held therein, comprising the following steps of accommodating the electronic devices in a plurality of device holes defined in the embossed carrier tape respectively, and winding the embossed carrier tape around a tape reel with predetermined spaces respectively defined between lower surfaces of the overlapping one device holes and upper surfaces of the overlapping other device holes upon successively winding the same therearound.
    • 为了解决上述问题,本发明提供了一种压纹载带,其包括以预定间隔限定在压花载带材料中的多个装置孔,以便将电子装置保持在其中,以及分别设置在相邻的装置孔之间的保护肋 。 另一个发明提供了一种用于其上保存有电子器件的压纹载带的带状方法,包括以下步骤:分别将电子器件容纳在限定在压花载带中的多个器件孔中,并将压花载带卷绕在带卷轴 其中分别限定在重叠的一个装置孔的下表面和重叠的另一个装置孔的上表面之间的预定空间,并在其周围连续缠绕。