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1. 发明授权

US5654322A Biphenylmethane derivatives and pharmaceuticals containing the same 失效
标题翻译：联苯甲烷衍生物和含有它们的药物
公开(公告)号：US5654322A
公开(公告)日：1997-08-05
申请号：US386649
申请日：1995-02-10
申请人： Terukage Hirata , Nobuya Sakae , Koichi Tamura , Masayasu Okuhira , Hirotaka Amano , Masaharu Yokomoto , Jun Nomiyama
发明人： Terukage Hirata , Nobuya Sakae , Koichi Tamura , Masayasu Okuhira , Hirotaka Amano , Masaharu Yokomoto , Jun Nomiyama
IPC分类号： C07D261/14 , C07D263/48 , C07D277/42 , C07D277/82 , C07D285/08 , C07D417/10 , A61K31/41
CPC分类号： C07D285/08 , C07D261/14 , C07D263/48 , C07D277/42 , C07D277/82 , C07D417/10
摘要： This invention relates to a biphenylmethane derivative represented by the formula (1): ##STR1## wherein A represents a group ##STR2## in which R.sup.1, X, Y, Z and B are as defined in the Specification. The compounds have potent angiotensin II antagonist activity and anti-hypertensive effect. They have therapeutic utility for circulatory diseases such as hypertension, heart diseases and cerebral apoplexy.
摘要翻译：本发明涉及由式（1）表示的联苯甲烷衍生物：其中A表示基团，其中R 1，X，Y，Z和B如本说明书中所定义。该化合物具有有效的血管紧张素II拮抗剂活性和抗高血压作用。它们具有循环系统疾病如高血压，心脏病和脑中风的治疗效用。

2. 发明授权

US06776495B2 Chemiluminescent device 失效
标题翻译：化学发光装置
公开(公告)号：US06776495B2
公开(公告)日：2004-08-17
申请号：US10315951
申请日：2002-12-11
申请人： Jun Nomiyama
发明人： Jun Nomiyama
IPC分类号： F21K206
CPC分类号： F21K2/06
摘要： The chemiluminescent device has a luminous body capable of generating light through a chemiluminescent reaction, and an outer layer for covering the luminous body. The outer layer is made of closed-cell plastic foam having a forming ratio in the range of 3 to 50%, preferably in the range of 20 to 30%. Closed-cell foamed polyethylene having no adverse environmental effect may be advantageously used as the closed-cell plastic foam. The chemiluminescent device having the outer layer made of closed-cell plastic foam provides increased luminous area, unsusceptibility to ambient temperature, and enhanced softness and shock-absorbability to achieve satisfactory luminescent effect, safety and reliability. The outer layer may have an outer surface formed with an irregularity to provide further enhanced luminescent effect.
摘要翻译：化学发光装置具有能够通过化学发光反应产生光的发光体和用于覆盖发光体的外层。外层由闭孔塑料泡沫制成，其成型比例在3-50％范围内，优选在20-30％范围内。可以有利地使用不具有不利环境影响的闭孔泡沫聚乙烯泡沫塑料泡沫。具有由闭孔塑料泡沫制成的外层的化学发光装置提供增加的发光面积，对环境温度的不可接受性，以及增强的柔软性和冲击吸收性，以获得令人满意的发光效果，安全性和可靠性。外层可以具有形成为不规则的外表面以提供进一步增强的发光效果。

3. 发明授权

US5026856A Isoindoline derivative 失效
标题翻译：异二氢吲哚衍生物
公开(公告)号：US5026856A
公开(公告)日：1991-06-25
申请号：US356059
申请日：1989-05-23
申请人： Takashi Yatsunami , Akira Yazaki , Satoshi Inoue , Hitoshi Yamamoto , Masaharu Yokomoto , Jun Nomiyama , Shuichiro Noda
发明人： Takashi Yatsunami , Akira Yazaki , Satoshi Inoue , Hitoshi Yamamoto , Masaharu Yokomoto , Jun Nomiyama , Shuichiro Noda
IPC分类号： A23L3/3544 , A01N43/90 , A61K31/47 , A61K31/535 , A61P31/04 , C07D401/04 , C07D471/04 , C07D498/06
CPC分类号： C07D401/04 , C07D471/04 , Y02P20/55
摘要： Isoindoline derivatives represented by the formula (I) and their salts are disclosed. ##STR1## There are many varieties for the compound depending on the types of residues R.sup.1 -R.sup.9 and X. The compounds can be prepared from quinoline derivatives of the formula (II) and an isoindoline derivatives of the formula (III). The compounds of formula (I) and their salts have excellent antibacterial activities against both gram positive and gram negative microorganisms. They can be used as a medicine, an agrichemical, and a food preservative.

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