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    • 1. 发明申请
    • Smart disposable plastic lab-on-a-chip for point-of-care testing
    • 智能一次性塑料实验室用于点护理测试
    • US20050130292A1
    • 2005-06-16
    • US10947577
    • 2004-09-22
    • Chong AhnJin-Woo ChoiGregory BeaucageJoseph Nevin
    • Chong AhnJin-Woo ChoiGregory BeaucageJoseph Nevin
    • A61M31/00C12M1/34C12Q1/68H01L21/00
    • A61B5/1495A61B5/14532A61B5/1486
    • Disclosed herein is a fully-integrated, disposable biochip for point-of-care testing of clinically relevant parameters. Specifically, in accordance with an embodiment of the present invention, the biochip is designed for POCT (point-of-care-testing) of an array of metabolic parameters including partial pressure of oxygen, Glucose, and Lactate concentration from venous blood samples. The biochip is fabricated on a low-cost plastic substrate using mass manufacturing compatible fabrication processes. Furthermore, the biochip contains a fully-integrated metallic micro-needle for blood sampling. The biochip also uses smart passive microfluidics in conjunction with low-power functional on-chip pressure generators for microfluidic sequencing. The design, configuration, assembly and operation of the biochip are ideally suited for a disposable biochip specifically targeted towards POCT applications.
    • 本文公开了一种完全集成的一次性生物芯片,用于临床相关参数的护理点测试。 具体地,根据本发明的实施例,生物芯片被设计用于代谢参数阵列的POCT(点护理测试),包括来自静脉血样品的氧分压,葡萄糖和乳酸盐浓度。 使用大规模制造兼容的制造工艺,在低成本塑料基板上制造生物芯片。 此外,生物芯片包含用于血液取样的完全集成的金属微针。 生物芯片还使用智能无源微流体结合低功耗片上压力发生器进行微流控测序。 生物芯片的设计,配置,组装和操作非常适合专门针对POCT应用的一次性生物芯片。
    • 2. 发明授权
    • Smart disposable plastic lab-on-a-chip for point-of-care testing
    • 智能一次性塑料实验室用于点护理测试
    • US07524464B2
    • 2009-04-28
    • US10947577
    • 2004-09-22
    • Chong H. AhnJin-Woo ChoiGregory BeaucageJoseph Nevin
    • Chong H. AhnJin-Woo ChoiGregory BeaucageJoseph Nevin
    • C12M1/68C12M1/34H01L21/00
    • A61B5/1495A61B5/14532A61B5/1486
    • Disclosed herein is a fully-integrated, disposable biochip for point-of-care testing of clinically relevant parameters. Specifically, in accordance with an embodiment of the present invention, the biochip is designed for POCT (point-of-care-testing) of an array of metabolic parameters including partial pressure of oxygen, Glucose, and Lactate concentration from venous blood samples. The biochip is fabricated on a low-cost plastic substrate using mass manufacturing compatible fabrication processes. Furthermore, the biochip contains a fully-integrated metallic micro-needle for blood sampling. The biochip also uses smart passive microfluidics in conjunction with low-power functional on-chip pressure generators for microfluidic sequencing. The design, configuration, assembly and operation of the biochip are ideally suited for a disposable biochip specifically targeted towards POCT applications.
    • 本文公开了一种完全集成的一次性生物芯片,用于临床相关参数的护理点测试。 具体地,根据本发明的实施例,生物芯片被设计用于代谢参数阵列的POCT(点护理测试),包括来自静脉血样品的氧分压,葡萄糖和乳酸盐浓度。 使用大规模制造兼容的制造工艺,在低成本塑料基板上制造生物芯片。 此外,生物芯片包含用于血液取样的完全集成的金属微针。 生物芯片还使用智能无源微流体结合低功耗片上压力发生器进行微流控测序。 生物芯片的设计,配置,组装和操作非常适合专门针对POCT应用的一次性生物芯片。