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    • 4. 发明申请
    • EXPANDABLE VEIN LIGATOR CATHETER HAVING MULTIPLE ELECTRODE LEADS, AND METHOD
    • 具有多个电极引线的可扩展的导管引线和方法
    • US20090137998A1
    • 2009-05-28
    • US12181277
    • 2008-07-28
    • Arthur W. ZikorusMark P. ParkerChristopher S. JonesDouglas M. PettyBrian E. FarleyJoseph M. Tartaglia
    • Arthur W. ZikorusMark P. ParkerChristopher S. JonesDouglas M. PettyBrian E. FarleyJoseph M. Tartaglia
    • A61B18/18
    • A61B18/1492A61B2017/00084A61B2017/22038A61B2017/22051A61B2018/00214A61B2018/0022A61B2018/00404A61B2018/124A61B2018/1253A61B2018/126A61B2018/1475A61B2090/3782A61B2218/002
    • A catheter includes a plurality of primary leads to deliver energy for ligating a hollow anatomical structure. Each of the primary leads includes an electrode located at the working end of the catheter. Separation is maintained between the primary leads such that each primary lead can individually receive power of selected polarity. The primary leads are constructed to expand outwardly to place the electrodes into apposition with an anatomical structure. High frequency energy can be applied from the leads to create a heating effect in the surrounding tissue of the anatomical structure. The diameter of the hollow anatomical structure is reduced by the heating effect, and the electrodes of the primary leads are moved closer to one another. Where the hollow anatomical structure is a vein, energy is applied until the diameter of the vein is reduced to the point where the vein is occluded. In one embodiment, a secondary lead is surrounded by the primary leads, and extends beyond the primary leads. The secondary lead includes an electrode at the working end of the catheter. The secondary lead can have a polarity opposite to the polarity of the primary leads in a bipolar configuration. The polarity of the leads can be switched and the catheter can be moved during treatment to ligate an extended length of the vein. The catheter can include a lumen to accommodate a guide wire or to allow fluid delivery.
    • 导管包括多个主引线以传递用于结扎中空解剖结构的能量。 每个主引线包括位于导管工作端的电极。 在主引线之间保持分离,使得每个主引线可以分别接收所选极性的功率。 主引线被构造成向外扩展以使电极与解剖结构相配合。 可以从引线施加高频能量以在解剖结构的周围组织中产生加热效果。 中空解剖结构的直径由于加热效应而降低,并且主引线的电极彼此靠近地移动。 当中空解剖结构为静脉时,施加能量直到静脉的直径减小到静脉闭塞的位置。 在一个实施例中,次级引线被主引线包围,并且延伸超出主引线。 次级引线包括在导管的工作端的电极。 次级引线可以具有与双极配置中的主引线的极性相反的极性。 可以切换引线的极性,并且可以在治疗期间移动导管以连接延长的静脉长度。 导管可以包括用于容纳导丝或者允许流体输送的内腔。
    • 5. 发明授权
    • Endoscope with guiding apparatus
    • 带引导装置的内窥镜
    • US06800056B2
    • 2004-10-05
    • US10087100
    • 2002-03-01
    • Joseph M. TartagliaAmir BelsonRobert Matthew Ohline
    • Joseph M. TartagliaAmir BelsonRobert Matthew Ohline
    • A61B100
    • A61B1/31A61B1/00078A61B1/00082A61B1/0053A61B1/0055A61B1/01A61B1/07A61B5/065A61B2034/301
    • An endoscope with guiding apparatus is described herein. A steerable endoscope is described having an elongate body with a manually or selectively steerable distal portion, an automatically controlled portion, a flexible and passively manipulated proximal portion, and an externally controlled and manipulatable tracking rod or guide. The tracking rod or guide is positioned within a guide channel within the endoscope and slides relative to the endoscope. When the guide is in a flexible state, it can conform to a curve or path defined by the steerable distal portion and the automatically controlled portion. The guide can then be selectively rigidized to assume that curve or path. Once set, the endoscope can be advanced over the rigidized guide in a monorail or “piggy-back” fashion so that the flexible proximal portion follows the curve held by the guide until the endoscope reaches a next point of curvature within a body lumen.
    • 本文描述了具有引导装置的内窥镜。 描述了一种可操纵的内窥镜,其具有带有手动或选择性可操纵的远端部分的细长主体,自动控制部分,柔性和被动操纵的近端部分以及外部控制和可操纵的跟踪杆或引导件。 跟踪杆或引导件位于内窥镜内的引导通道内并相对于内窥镜滑动。 当引导件处于柔性状态时,其可以符合由可转向远端部分和自动控制部分限定的曲线或路径。 然后,引导件可以选择性地刚性化以假定该曲线或路径。 一旦设定,内窥镜可以以单轨或“背部”的方式前进在刚性引导件上,使得柔性近端部分遵循由引导件保持的曲线,直到内窥镜到达体腔内的下一个曲率点。
    • 6. 发明授权
    • Expandable vein ligator catheter having multiple electrode leads
    • 具有多个电极引线的可扩展静脉结扎器导管
    • US06200312B1
    • 2001-03-13
    • US08927251
    • 1997-09-11
    • Arthur W. ZikorusMark P. ParkerChristopher S. JonesDouglas M. PettyBrian E. FarleyJoseph M. Tartaglia
    • Arthur W. ZikorusMark P. ParkerChristopher S. JonesDouglas M. PettyBrian E. FarleyJoseph M. Tartaglia
    • A61B1738
    • A61B18/1492A61B2017/00084A61B2017/22038A61B2017/22051A61B2018/00214A61B2018/0022A61B2018/00404A61B2018/124A61B2018/1253A61B2018/126A61B2018/1475A61B2090/3782A61B2218/002
    • A catheter includes a plurality of primary leads to deliver energy for ligating a hollow anatomical structure. Each of the primary leads includes an electrode located at the working end of the catheter. Separation is maintained between the primary leads such that each primary lead can individually receive power of selected polarity. The primary leads are constructed to expand outwardly to place the electrodes into apposition with an anatomical structure. High frequency energy can be applied from the leads to create a heating effect in the surrounding tissue of the anatomical structure. The diameter of the hollow anatomical structure is reduced by the heating effect, and the electrodes of the primary leads are moved closer to one another. Where the hollow anatomical structure is a vein, energy is applied until the diameter of the vein is reduced to the point where the vein is occluded. In one embodiment, a secondary lead is surrounded by the primary leads, and extends beyond the primary leads. The secondary lead includes an electrode at the working end of the catheter. The secondary lead can have a polarity opposite to the polarity of the primary leads in a bipolar configuration. The polarity of the leads can be switched and the catheter can be moved during treatment to ligate an extended length of the vein. The catheter can include a lumen to accommodate a guide wire or to allow fluid delivery.
    • 导管包括多个主引线以传递用于结扎中空解剖结构的能量。 每个主引线包括位于导管工作端的电极。 在主引线之间保持分离,使得每个主引线可以分别接收所选极性的功率。 主引线被构造成向外扩展以使电极与解剖结构相配合。 可以从引线施加高频能量以在解剖结构的周围组织中产生加热效果。 中空解剖结构的直径由于加热效应而降低,并且主引线的电极彼此靠近地移动。 当中空解剖结构为静脉时,施加能量直到静脉的直径减小到静脉闭塞的位置。 在一个实施例中,次级引线被主引线包围,并且延伸超出主引线。 次级引线包括在导管的工作端的电极。 次级引线可以具有与双极配置中的主引线的极性相反的极性。 可以切换引线的极性,并且可以在治疗期间移动导管以连接延长的静脉长度。 导管可以包括用于容纳导丝或者允许流体输送的内腔。
    • 9. 发明授权
    • Polymer film for wrapping a stent structure
    • 用于包裹支架结构的聚合物膜
    • US5637113A
    • 1997-06-10
    • US355402
    • 1994-12-13
    • Joseph M. TartagliaJoseph P. LoefflerTodd H. Turnlund
    • Joseph M. TartagliaJoseph P. LoefflerTodd H. Turnlund
    • A61M31/00A61F2/00A61F2/82A61F2/92A61L27/00A61L31/00A61F2/06
    • A61F2/82A61F2/07A61F2/92A61F2/915A61F2002/075A61F2220/005A61F2250/0067
    • The drug loaded stent includes an expandable stent structural member, and a planar sheet of polymeric material attached to the outside of the expandable stent structural member. The polymeric material is preferably bioabsorbable, and loaded or coated with a therapeutic agent or drug to reduce or prevent restenosis in the vessel being treated. The polymer material can be attached to the metal stent at one or more points, and wrapped in a coil around the stent in an unexpanded state, to uncoil and expand in diameter to substantially match the expanded diameter of the metal stent; or can be wrapped tightly around the stent structural member and attached to itself, to stretch radially when the stent structural member is expanded. In another currently preferred embodiment, a combination of a stent structural member and a polymeric film wrapping can be provided with a coating of lubricious material. The lubricious material can be polyethylene oxide, polyethylene glycol, polyethylene acetate, polyvinyl pyrrolidone, polyvinyl alcohol, polyacrylamide, hydrophilic soft segment urethanes, some natural gums, polyanhydrides or other similar hydrophilic polymers, and combinations thereof. The layer of lubricious material protects the stent from the guide or the body lumen in which the stent is inserted by providing a low friction surface over the stent.
    • 药物负载支架包括可扩张的支架结构构件和附接到可扩张支架结构构件的外侧的聚合物材料的平面片。 聚合物材料优选是生物可吸收的,并且加载或涂覆有治疗剂或药物以减少或预防待治疗血管中的再狭窄。 聚合物材料可以以一个或多个点附着到金属支架上,并且以未膨胀的状态包裹在支架周围的线圈中,以直径展开和膨胀以与金属支架的扩张直径基本匹配; 或者可以紧紧地包裹在支架结构构件上并且附接到其自身,以在支架结构构件膨胀时径向拉伸。 在另一个目前优选的实施方案中,支架结构构件和聚合物膜包裹物的组合可以提供有润滑材料的涂层。 润滑材料可以是聚环氧乙烷,聚乙二醇,聚乙酸乙烯酯,聚乙烯吡咯烷酮,聚乙烯醇,聚丙烯酰胺,亲水性软链段聚氨酯,一些天然树胶,聚酐或其它类似的亲水聚合物,及其组合。 光滑材料层通过在支架上提供低摩擦表面来保护支架免于插入支架的引导件或体腔。
    • 10. 发明授权
    • Expandable vein ligator catheter having multiple electrode leads, and method
    • 具有多个电极引线的可扩展静脉结扎器导管及方法
    • US08679110B2
    • 2014-03-25
    • US12181277
    • 2008-07-28
    • Arthur W. ZikorusMark P. ParkerChristopher S. JonesDouglas M. PettyBrian E. FarleyJoseph M. Tartaglia
    • Arthur W. ZikorusMark P. ParkerChristopher S. JonesDouglas M. PettyBrian E. FarleyJoseph M. Tartaglia
    • A61F5/56A61B18/18A61B18/20
    • A61B18/1492A61B2017/00084A61B2017/22038A61B2017/22051A61B2018/00214A61B2018/0022A61B2018/00404A61B2018/124A61B2018/1253A61B2018/126A61B2018/1475A61B2090/3782A61B2218/002
    • A catheter includes a plurality of primary leads to deliver energy for ligating a hollow anatomical structure. Each of the primary leads includes an electrode located at the working end of the catheter. Separation is maintained between the primary leads such that each primary lead can individually receive power of selected polarity. The primary leads are constructed to expand outwardly to place the electrodes into apposition with an anatomical structure. High frequency energy can be applied from the leads to create a heating effect in the surrounding tissue of the anatomical structure. The diameter of the hollow anatomical structure is reduced by the heating effect, and the electrodes of the primary leads are moved closer to one another. Where the hollow anatomical structure is a vein, energy is applied until the diameter of the vein is reduced to the point where the vein is occluded. In one embodiment, a secondary lead is surrounded by the primary leads, and extends beyond the primary leads. The secondary lead includes an electrode at the working end of the catheter. The secondary lead can have a polarity opposite to the polarity of the primary leads in a bipolar configuration. The polarity of the leads can be switched and the catheter can be moved during treatment to ligate an extended length of the vein. The catheter can include a lumen to accommodate a guide wire or to allow fluid delivery.
    • 导管包括多个主引线以传递用于结扎中空解剖结构的能量。 每个主引线包括位于导管工作端的电极。 在主引线之间保持分离,使得每个主引线可以分别接收所选极性的功率。 主引线被构造成向外扩展以使电极与解剖结构相配合。 可以从引线施加高频能量以在解剖结构的周围组织中产生加热效果。 中空解剖结构的直径由于加热效应而降低,并且主引线的电极彼此靠近地移动。 当中空解剖结构为静脉时,施加能量直到静脉的直径减小到静脉闭塞的位置。 在一个实施例中,次级引线被主引线包围,并且延伸超出主引线。 次级引线包括在导管的工作端的电极。 次级引线可以具有与双极配置中的主引线的极性相反的极性。 可以切换引线的极性,并且可以在治疗期间移动导管以连接延长的静脉长度。 导管可以包括用于容纳导丝或者允许流体输送的内腔。