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    • 3. 发明申请
    • Azetidinium modified polymers and fabric treatment composition
    • 氮杂环丁烷改性聚合物和织物处理组合物
    • US20050060812A1
    • 2005-03-24
    • US10501499
    • 2002-12-10
    • Stephen BatchelorPaul FindlayJoseph HunterAndrew ParkerStephen Rannard
    • Stephen BatchelorPaul FindlayJoseph HunterAndrew ParkerStephen Rannard
    • C08F8/00D06M10/00
    • C08F8/02C08F2800/10C08F2800/20C08F8/08C08F2220/281C08F220/34C08F2220/286
    • The invention relates to a fabric treatment composition which comprises a self-crosslinking polymer possessing pendant azetidinium groups. A first aspect of the invention comprises an azetidinium functionalised polymer containing primary or secondary amine groups. Cross-linking reactions between the azetidinium group and primary or secondary amine groups does not form quaternary groups and consequently does not result in a charged, cross-linked polymer. This lack of charge is believed to overcome the problems of stain fixing and dye adsorption. A second aspect of the present invention subsists in a azetidinium functionalized polymer of which the monomers comprise: an amino-acrylate and/or amino-alkacrylate monomer, and, optionally, further non-amino acrylate and/or alkacrylate monomer. A third aspect of the present invention provides a textile treatment composition which comprises a azetidinium functionalised polymer in accordance with the first or second aspect of the invention and a textile compatible carrier.
    • 本发明涉及一种织物处理组合物,其包含具有氮杂吖啶基侧基的自交联聚合物。 本发明的第一方面包括含有伯胺基或仲胺基团的氮杂环丁烷官能化聚合物。 氮杂环丁烷基与伯胺或仲胺基之间的交联反应不形成季基,因此不会导致带电的交联聚合物。 认为这种缺乏电荷可以克服染色剂固定和染料吸附的问题。 本发明的第二方面存在于氮杂环丁烷官能化聚合物中,其单体包括:氨基 - 丙烯酸酯和/或氨基 - 丙烯酸烷基酯单体,以及任选的其它非氨基丙烯酸酯和/或丙烯酸烷基酯单体。 本发明的第三方面提供一种纺织品处理组合物,其包含根据本发明的第一或第二方面的氮杂环丁烷官能化聚合物和纺织品相容的载体。
    • 6. 发明申请
    • Non Destructive Testing Apparatus and Method Using Ultrasound Imaging
    • 非破坏性测试仪器和使用超声成像的方法
    • US20140140167A1
    • 2014-05-22
    • US14130350
    • 2012-06-29
    • Alan Joseph HunterArno Willem Frederik Volker
    • Alan Joseph HunterArno Willem Frederik Volker
    • G01N29/07
    • G01N29/07G01N29/069G01N2291/044G01S7/52049G01S15/8915G01S15/8952
    • Improved imaging is provided for structures under test that have propagation direction dependent ultrasound propagation speed or position dependent ultrasound propagation speed due to fibrous, coarse grain or single crystalline material. A set reflection points is selected in the structure under test and ultrasound propagation time delays between the reflection point or points on one hand and the plurality of positions on the other hand that fit an observed time delay of the detected reflections are computed. This may be done by means of an iterative method. In the iterative method a synthetically focused ultrasound beam is realized by summing measurements after compensation for propagation time delay from different transmitting transducers to the reflection points. Time delays to receiving transducers are measured from the arrival time of reflections of this synthetically focused ultrasound beam, and the propagation time delay from different transmitting transducers is iteratively adapted until it matches time delays corresponding to the measured arrival times. Time delays to other points in the structure under test are interpolated between the selected reflection points and used in the computation of an image of reflections within the structure under test.
    • 针对具有传播方向依赖的超声波传播速度或由于纤维状,粗粒状或单晶材料引起的位置相关超声传播速度的结构,提供改进的成像。 在被测结构中选择设定的反射点,并且计算一方面的反射点或者点之间的超声波传播时间延迟,另一方面计算适合所检测的反射的观察时间延迟的多个位置。 这可以通过迭代方法来完成。 在迭代方法中,通过对从不同发射传感器到反射点的传播时间延迟进行补偿后的求和来实现合成聚焦超声波束。 从该合成聚焦超声波束的反射的到达时间测量接收换能器的时间延迟,并且迭代地适配来自不同发射换能器的传播时间延迟,直到它匹配对应于测量的到达时间的时间延迟。 在所选择的反射点之间插入被测结构中其他点的时间延迟,并用于计算被测结构内的反射图像。
    • 9. 发明授权
    • Methods for using 22045, a human cyclic nucleotide phosphodiesterase
    • 使用22045的人类环状核苷酸磷酸二酯酶的方法
    • US06673564B2
    • 2004-01-06
    • US09420190
    • 1999-10-18
    • Rosana Kapeller-LibermannJohn Joseph HunterMark Williamson
    • Rosana Kapeller-LibermannJohn Joseph HunterMark Williamson
    • C12Q144
    • C12N9/16A61K38/00
    • The present invention relates to methods for using a human cyclic nucleotide phosphodiesterase belonging to the superfamily of mammalian phosphodiesterases. The invention also relates to methods for using polynucleotides encoding the phosphodiesterase. The invention relates to methods using the phosphodiesterase polypeptides and polynucleotides as a target for diagnosis and treatment in phosphodiesterase-mediated or -related disorders. The invention further relates to drug-screening methods using the phosphodiesterase polypeptides and polynucleotides to identify agonists and antagonists for diagnosis and treatment. The invention further encompasses agonists and antagonists based on the phosphodiesterase polypeptides and polynucleotides. The invention further relates to agonists and antagonists identifiefd by drug screening methods with the phosphodiesterase polypeptides and polynucleotides as a target.
    • 本发明涉及使用属于哺乳动物磷酸二酯酶超家族的人环状核苷酸磷酸二酯酶的方法。 本发明还涉及使用编码磷酸二酯酶的多核苷酸的方法。 本发明涉及使用磷酸二酯酶多肽和多核苷酸作为磷酸二酯酶介导的或相关疾病中的诊断和治疗的靶标的方法。 本发明还涉及使用磷酸二酯酶多肽和多核苷酸鉴定用于诊断和治疗的激动剂和拮抗剂的药物筛选方法。 本发明还包括基于磷酸二酯酶多肽和多核苷酸的激动剂和拮抗剂。 本发明还涉及用磷酸二酯酶多肽和多核苷酸作为靶标的药物筛选方法鉴定的激动剂和拮抗剂。