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1. 发明申请

US20200221902A1 Platform Having Multiple Adjustable Work Areas 审中-公开
公开(公告)号：US20200221902A1
公开(公告)日：2020-07-16
申请号：US16833941
申请日：2020-03-30
申请人： JOHN WATSON, JR.
发明人： JOHN WATSON, JR.
IPC分类号： A47J37/07 , B62D63/08 , F24B1/20
摘要： A platform having adjustable working areas that can be repositioned from a stored position to an operational position on the platform wherein each of the work areas are horizontally adjustable to allow each of the work areas to be independently adjustable.

2. 发明授权

US08939308B2 Full aperture beverage end 有权
标题翻译：全口径饮料端
公开(公告)号：US08939308B2
公开(公告)日：2015-01-27
申请号：US12797171
申请日：2010-06-09
申请人： Christopher Paul Ramsey , Garry Richard Chant , Andrew Robert Lockley , Brian Fields , Martin John Watson , Eleanor Rachel Ann Hyde
发明人： Christopher Paul Ramsey , Garry Richard Chant , Andrew Robert Lockley , Brian Fields , Martin John Watson , Eleanor Rachel Ann Hyde
IPC分类号： B65D17/353 , B65D17/347 , B65D17/34 , B65D17/00
CPC分类号： B65D17/4012 , B65D1/12 , B65D17/4011 , B65D17/404 , B65D2517/0013
摘要： A full aperture beverage end has a center panel, a countersink surrounding the center panel, a main score arranged in proximity to the countersink to define a removable aperture panel and a vent score. The beverage end is adapted for use with products that are pressurized to over 30 psi (200 kPa) when opened, and during opening the vent score is adapted to sever first, controlling the pressure differential between the external surface and internal surface of the center panel, thereby allowing the main score to tear in a controlled and reliable manner.
摘要翻译：全孔饮料端部具有中心面板，围绕中心面板的沉孔，布置在锪孔附近的主要刻痕，以限定可移除孔径面板和排气口分数。饮料端适用于打开时被加压至超过30psi（200kPa）的产品，并且在打开期间，排气分数首先被切断，控制中心面板的外表面和内表面之间的压力差，从而允许主分数以受控和可靠的方式撕裂。

3. 发明申请

US20140018725A1 DRUG DELIVERY TECHNOLOGY 审中-公开
标题翻译：药物递送技术
公开(公告)号：US20140018725A1
公开(公告)日：2014-01-16
申请号：US13980723
申请日：2012-01-20
申请人： Charles Potter , John Watson
发明人： Charles Potter , John Watson
IPC分类号： A61M37/00
CPC分类号： A61M37/0069 , A61B17/3468 , A61M31/007 , A61M2005/005
摘要： The present invention relates to novel drug delivery technology in the form of solid dose injection devices and methods which utilise a blade that is pushed into the skin to a predetermined depth before the before a solid drug formulation is pushed into the cut made by the blade. Thus the present invention also relates to delivering a therapeutic compound to a human or animal in the form of a solid dose injection comprising: providing an injection device comprising a casing; an actuation mechanism capable of ei generating a force, a blade, a solid drug formulation; and a means for pushing said solid drug formulation; wherein the blade is inser ted to a predetermined depth in the skin and, following insertion of the blade, the device is actuated such that the actuation mechanism capable of generating a force acts on the means for pushing to push the solid drug formulation out of the casing and into the human or animal body.
摘要翻译：本发明涉及以固体剂量注射装置和方法形式的新型药物递送技术，其利用在固体药物制剂被推入由刀片制成的切口之前被推入皮肤中的刀片达预定深度。因此，本发明还涉及以固体剂量注射的形式将治疗性化合物递送至人或动物，其包括：提供包括壳体的注射装置; 能够产生力的致动机构，叶片，固体药物制剂; 以及推动所述固体药物制剂的方法; 其中所述刀片插入到所述皮肤中的预定深度，并且在所述刀片插入之后，所述装置被致动，使得能够产生力的所述致动机构作用于推动所述固体药物制剂的装置套管并进入人体或动物体内。

4. 发明授权

US08318674B2 Local treatment of bone defects 有权
标题翻译：局部治疗骨缺损
公开(公告)号：US08318674B2
公开(公告)日：2012-11-27
申请号：US11326924
申请日：2006-01-06
申请人： Jason Schense , John Watson , Isabelle Arrighi
发明人： Jason Schense , John Watson , Isabelle Arrighi
IPC分类号： A61K38/29 , A61K38/00 , C07K14/635 , A61P19/08 , A61P19/10 , A61P5/18 , C12N15/00
CPC分类号： A61K38/39 , A61K38/1875 , A61K38/29 , A61K38/4833 , A61L27/225 , A61L27/227 , A61L2400/06 , A61L2430/02 , A61K2300/00
摘要： A method of local treatment of specific bone defects such as osteoporosis or bone cysts comprises the step of local administration of a formulation comprising a fusion peptide containing a first domain comprising PTH or BMP 2 or BMP 7, and a second domain comprising a covalently crosslinkable substrate domain; and a material suitable of forming a biodegradable matrix suitable for cellular growth or in-growth, wherein the fusion peptide is covalently linked to the matrix. In one embodiment, the matrix contains one or more contrast agents, and is preferably formed in the absence of a growth factor. The matrix may be used in the treatment of fluid-filled cysts such as Tarlov cysts, ovarian cysts, arachnoid cysts, aneurysmal bone cysts or hepatic cysts.
摘要翻译：局部治疗特定骨缺损如骨质疏松症或骨囊肿的方法包括局部施用包含含有包含PTH或BMP 2或BMP 7的第一结构域的融合肽的制剂的步骤，以及包含共价可交联底物的第二结构域域; 以及适于形成适于细胞生长或生长的可生物降解的基质的材料，其中所述融合肽与所述基质共价连接。在一个实施方案中，基质含有一种或多种造影剂，优选在不存在生长因子的情况下形成。该基质可用于治疗流体充满囊肿如Tarlov囊肿，卵巢囊肿，蛛网膜囊肿，动脉瘤性骨囊肿或肝囊肿。

5. 发明申请

US20120136191A1 CATALYST AND PROCESS 审中-公开
标题翻译：催化剂和工艺
公开(公告)号：US20120136191A1
公开(公告)日：2012-05-31
申请号：US13376301
申请日：2010-06-04
申请人： Edmund Hugh Stitt , Michael John Watson , Lynn Gladden , James McGregor
发明人： Edmund Hugh Stitt , Michael John Watson , Lynn Gladden , James McGregor
IPC分类号： C07C5/333 , B82Y30/00
CPC分类号： B01J21/185 , B01J23/22 , B01J23/745 , B01J35/1014 , B01J35/1019 , B01J37/0201 , B01J37/084 , B82Y30/00 , C07C5/333 , C07C5/3332 , C07C5/3335 , C07C5/3337 , C07C2521/18 , C07C2523/22 , C07C2523/26 , C07C2523/28 , C07C2523/34 , C07C2523/36 , C07C2523/42 , C07C2523/44 , C07C2523/46 , C07C2523/52 , C07C2523/745 , C07C2523/75 , C07C2523/76 , C07C11/00
摘要： The invention is a method of dehydrogenating a hydrocarbon, especially an alkane, to form an unsaturated compound, especially an alkene, by contacting the alkane with a catalyst comprising a form of carbon which is catalytically active for the dehydrogenation reaction. The catalyst may be formed by passing a hydrocarbon over a metal compound at a temperature greater than 650° C.
摘要翻译：本发明是通过使烷烃与包含对于脱氢反应具有催化活性的碳形式的催化剂接触来使烃，特别是烷烃脱氢以形成不饱和化合物，特别是烯烃的方法。催化剂可以通过在大于650℃的温度下使烃在金属化合物上通过而形成。

6. 发明申请

US20110311643A1 SUPPLEMENTED MATRICES FOR THE REPAIR OF BONE FRACTURES 有权
标题翻译：骨折修复的补充基准
公开(公告)号：US20110311643A1
公开(公告)日：2011-12-22
申请号：US13167488
申请日：2011-06-23
申请人： Jason Schense , John Watson , Isabelle Arrighi
发明人： Jason Schense , John Watson , Isabelle Arrighi
IPC分类号： A61K38/29 , A61K33/06 , A61P19/08 , A61K33/42
CPC分类号： A61K38/29 , A61L27/225 , A61L27/427 , A61L27/46 , A61L27/54 , A61L2300/252 , A61L2300/43 , A61L2430/02 , C07K14/635 , C07K2319/00
摘要： Supplemented matrices comprising a PTH releasably incorporated therein, optionally containing a granular material, which are used to heal bone fractures, particularly bone fractures with a risk of becoming delayed unions or non-unions, are described herein. The PTH is incorporated either through covalent linkage to the matrix or through non-covalent interaction with the matrix and/or the granules. These supplemented matrices decrease the time of healing compared to autograft and or trigger healing of bone fractures which otherwise would not heal. The matrices are biocompatible, preferably biodegradable, and can be formed in vitro or in vivo, at the time of implantation. The PTH may be a part of a fusion peptide. PTH can be incorporated into the matrices with full retention of its bioactivity. PTH can be releasably incorporated in the matrix.
摘要翻译：本文描述了包含可释放地并入其中的PTH的补充基质，任选地含有颗粒材料，其用于治疗骨折，特别是具有变为延迟联合或非联合的风险的骨折。通过共价连接到基质中或通过与基质和/或颗粒的非共价相互作用掺入PTH。与自体移植相比，这些补充的基质减少愈合时间和/或触发骨折的愈合，否则不会愈合。基质是生物相容的，优选可生物降解的，并且可以在植入时在体外或体内形成。 PTH可能是融合肽的一部分。 PTH可以并入到具有完全保留其生物活性的基质中。 PTH可以可释放地并入基质中。

7. 发明申请

US20090325555A1 System For Adapting Device Standars After Manufacture 审中-公开
标题翻译：制造后适应设备标准的系统
公开(公告)号：US20090325555A1
公开(公告)日：2009-12-31
申请号：US12554402
申请日：2009-09-04
申请人： Paul L. Master , John Watson
发明人： Paul L. Master , John Watson
IPC分类号： H04M3/42 , G06Q30/00 , G06Q50/00
CPC分类号： G06Q30/02
摘要： A system for efficient sale of devices that comply with licensed standards. A preferred embodiment of the invention uses a generic, or highly adaptable, hardware device. The device can be adapted to adhere to a specific standard, e.g., code-division multiple access, time-division multiple access, etc., after manufacture such as at the point-of-sale to an end user, prior to distribution, or at some other point in a distribution and sales network. This allows manufacturers, retailers and end users to benefit from more competitive selection of standardized communication, data and other formats. Reduction of manufacturing costs and elimination of shipping, or other transfer and storage costs, is also realized.
摘要翻译：一种高效销售符合许可标准的设备的系统。本发明的优选实施例使用通用或高适应性的硬件设备。该设备可以在分发之前适应于遵守特定标准，例如在制造之后的码分多址，时分多路访问等，在销售点到最终用户，或者在分销和销售网络的其他一点。这允许制造商，零售商和最终用户从更具竞争力的标准化通信，数据和其他格式的选择中受益。降低制造成本和消除运输，或其他转运和储存成本也得以实现。

8. 发明授权

US07521124B2 Silicones having improved chemical resistance and curable silicone compositions having improved migration resistance 有权
标题翻译：具有改善的耐化学性的硅酮和具有改善的耐迁移性的可固化的有机硅组合物
公开(公告)号：US07521124B2
公开(公告)日：2009-04-21
申请号：US11180456
申请日：2005-07-13
申请人： Dongchan Ahn , Pamela Jean Huey , Nick Evan Shephard , Michael John Watson
发明人： Dongchan Ahn , Pamela Jean Huey , Nick Evan Shephard , Michael John Watson
IPC分类号： C08G77/24
CPC分类号： C08L83/04 , C08G77/12 , C08G77/16 , C08G77/18 , C08G77/20 , C08G77/24 , C08G77/80 , C08L83/00 , C08L83/08 , C09D183/04 , C09D183/08 , C09J183/04 , H01L23/293 , H01L23/3114 , H01L23/3128 , H01L24/48 , H01L24/73 , H01L2224/32145 , H01L2224/32225 , H01L2224/48091 , H01L2224/48227 , H01L2224/73265 , H01L2924/00014 , H01L2924/01004 , H01L2924/01012 , H01L2924/01019 , H01L2924/0102 , H01L2924/01046 , H01L2924/01057 , H01L2924/01077 , H01L2924/01078 , H01L2924/01079 , H01L2924/12044 , H01L2924/15311 , H01L2924/181 , Y10T428/31663 , H01L2924/00 , H01L2924/00012 , H01L2224/45099 , H01L2224/45015 , H01L2924/207
摘要： A composition is prepared by mixing components including: (I) a polyorganosiloxane having an average of at least two unsaturated organic groups per molecule, with the proviso that component (I) is free of fluorine atoms; optionally (II) an organohydrogenpolysiloxane having an average of at least two silicon-bonded hydrogen atoms per molecule, with the proviso that component (II) is free of fluorine atoms; (III) a hydrosilylation catalyst; (IV) a fluoroorganosilicone, with the provisos that (1) component (IV) has at least one functional group reactive with component (I), component (II), or both, (2) when component (II) is not present, then component (IV) has an average of at least two silicon-bonded hydrogen atoms per molecule, and (3) component (IV) is added to the composition in an amount sufficient to provide chemical resistance to a cured product of the composition; and (V) an adhesion promoter.
摘要翻译：通过混合组分制备组合物，其包括：（I）每分子平均具有至少两个不饱和有机基团的聚有机硅氧烷，条件是组分（I）不含氟原子; 任选地（II）每分子平均具有至少两个与硅键合的氢原子的有机氢聚硅氧烷，条件是组分（II）不含氟原子; （III）氢化硅烷化催化剂; （IV）有机硅氧烷，条件是（1）组分（IV）具有至少一个与组分（I），组分（II）或两者反应的官能团，（2）当组分（II）不存在时，那么组分（Ⅳ）每分子具有平均至少两个与硅键合的氢原子，并且（3）组分（Ⅳ）以足以对组合物的固化产物提供耐化学性的量加入组合物中; 和（V）粘合促进剂。

9. 发明申请

US20080296970A1 Multiple Prime Power Source Locomotive Control 有权
标题翻译：多重电力机车控制
公开(公告)号：US20080296970A1
公开(公告)日：2008-12-04
申请号：US11912389
申请日：2006-04-25
申请人： Frank Donnelly , Andrew Tarnow , Bruce Wolff , John Watson
发明人： Frank Donnelly , Andrew Tarnow , Bruce Wolff , John Watson
IPC分类号： B60L15/20 , B61C3/00
CPC分类号： B60L11/123 , B60L7/06 , B60L7/14 , B60L7/22 , B60L9/00 , B60L9/16 , B60L11/005 , B60L11/12 , B60L11/16 , B60L2200/26 , B60L2220/12 , B60L2220/14 , B60L2220/18 , B60L2260/165 , B60L2260/167 , B61C7/04 , F02D25/04 , F02D29/06 , F02N7/10 , F02N11/04 , H02M2003/1552 , H02P9/305 , H02P25/16 , H02P2201/09 , Y02T10/6217 , Y02T10/7022 , Y02T10/7258 , Y02T30/16
摘要： The present invention is directed to a control strategy for operating a plurality of prune power sources (101-1 to 101-3) during propulsion, idling and braking and is applicable to large systems such as trucks, ships, cranes and locomotives utilizing diesel engines, gas turbine engines, other types of internal combustion engines, fuel cells or combinations of these that require substantial power and low emissions utilizing multiple power plant combinations The present invention is directed at a general control strategy for a multi-engine systems (101-1, 101-2) where the power systems need not be of the same type or power rating and may even use different fuels The invention is based on a common DC bus (103) electrical architecture so that prime power sources need not be synchronized
摘要翻译：本发明涉及一种用于在推进，空转和制动期间操作多个修剪动力源（101-1至101-3）的控制策略，并且适用于使用柴油发动机的大型系统如卡车，船舶，起重机和机车，燃气涡轮发动机，其他类型的内燃机，燃料电池或这些的组合，其需要使用多个发电厂组合的大量功率和低排放本发明涉及用于多发动机系统（101-1）的一般控制策略，101-2），其中电力系统不需要具有相同类型或额定功率并且甚至可以使用不同的燃料。本发明基于公共DC总线（103）电气架构，使得主电源不需要同步

10. 发明申请

US20080045257A1 Hands-Free Mode for a Half-Duplex Communications System 有权
标题翻译：半双工通信系统的免提模式
公开(公告)号：US20080045257A1
公开(公告)日：2008-02-21
申请号：US11573880
申请日：2005-08-17
申请人： John Watson
发明人： John Watson
IPC分类号： H04Q7/28
CPC分类号： H04W4/10 , H04L65/1016 , H04L65/4061 , H04W76/45 , H04W84/08
摘要： A half-duplex communication system is embodied in a push-to-talk cellular system such as a GPRS system. The system includes two or more terminals (10) one or more of which can operate in a hands-free mode. When in hands-free mode, a terminal (10) is offered the right-to-speak by the system without the need for a talk request from a user. This allows a hands-free user to participate safely in a call.
摘要翻译：半双工通信系统体现在诸如GPRS系统的即按即说蜂窝系统中。该系统包括两个或更多个终端（10），其中一个或多个可以在免提模式下操作。当在免提模式下，终端（10）被提供给系统的发言权，而不需要来自用户的通话请求。这允许免提用户安全地参与呼叫。

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